Lele Ye, Xuyang Yao, Binbing Xu, Wenwen Chen, Han Lou, Xinya Tong, Su Fang, Ruanmin Zou, Yingying Hu, Zhibin Wang, Dan Xiang, Qiaoai Lin, Shiyu Feng, Xiangyang Xue, Gangqiang Guo
Ovarian cancer (OC) is the most common female cancer worldwide. Patients with OC have high mortality because of its complex and poorly understood pathogenesis. RNA epigenetic modifications, such as m6 A, m1 A, and m5 C, are closely associated with the occurrence and development of OC. RNA modifications can affect the stability of mRNA transcripts, nuclear export of RNAs, translation efficiency, and decoding accuracy. However, there are few overviews that summarize the link between m6 A RNA modification and OC...
February 21, 2023: Wiley Interdisciplinary Reviews. RNA