Sunny P Orathel, Ronnie Thomas, N Chandramohanakumar, Joy Job Kulavelil, Krishnapillai Girish Kumar, Vadayath Usha Menon, P Jayaprakash, Sajitha Krishnan, P S Manju, Shaiju Param, M G Rajamanickam, U G Unnikrishnan, Joe Thomas, Ponnu Jose
Background: Perchlorate is an anion that occurs as a contaminant in groundwater. It originates from the improper disposal of ammonium perchlorate, a component of rocket fuel. The objective of this study was to explore whether the exposure to perchlorate in drinking water had an impact on the thyroid function of the population residing near an ammonium perchlorate plant in Kerala. Methodology . Using an ecological study design, we compared the serum levels of thyroid-stimulating hormone, thyroxine, and thyroid peroxidase antibodies among a representative sample of 289 study subjects from the area surrounding the ammonium perchlorate enrichment plant to 281 study subjects in a control area...
2020: Journal of Thyroid Research