journal
https://read.qxmd.com/read/38550755/tlr3-agonist-amplifies-the-anti-inflammatory-potency-of-adscs-via-il-10-mediated-macrophage-polarization-in-acute-pancreatitis
#1
JOURNAL ARTICLE
Jianxing Liu, Wenjing Yan, Shanshan Chen, Yingjie Sun, Fangfang Zhang, Yue Yang, Liang Jin
The immunoregulatory role of mesenchymal stem cells (MSCs) in inflammation is heterogeneous and can exhibit anti-inflammatory or proinflammatory properties depending on the microenvironment. We herein observed that the activation of Toll-like receptor 3 (TLR3) by polyinosinic : polycytidylic acid (poly(I : C)) stimulation facilitated the transformation of adipose-derived stem cells (ADSCs) into an anti-inflammatory phenotype. The enhanced anti-inflammatory properties were assessed in a taurocholate-induced pancreatitis model...
2024: Stem Cells International
https://read.qxmd.com/read/38510207/stimulated-human-umbilical-cord-mesenchymal-stem-cells-enhance-the-osteogenesis-and-cranial-bone-regeneration-through-il-32-mediated-p38-signaling-pathway
#2
JOURNAL ARTICLE
Xiaru Zhang, Ying Zheng, Gang Wang, Yuanlin Liu, Yang Wang, Xueyi Jiang, Yueqing Liang, Xinfeng Zhao, Ping Li, Yi Zhang
OBJECTIVE: Our previous study found that it could significantly increase the expression of IL32 after stimulating the human umbilical cord mesenchymal stem cells (S-HuMSCs). However, its role on the osteogenesis and cranial bone regeneration is still largely unknown. Here, we investigated the possible mechanism of this effect. Material and Methods . A series of experiments, including single-cell sequencing, flow cytometry, quantitative real-time polymerase chain reaction, and western blotting, were carried out to evaluate the characteristic and adipogenic-osteogenic differentiation potential of IL-32 overexpression HuMSCs (IL-32high HuMSCs) through mediating the P38 signaling pathway...
2024: Stem Cells International
https://read.qxmd.com/read/38435089/periostin-is-a-candidate-regulator-of-the-host-microenvironment-in-regeneration-of-pulp-and-dentin-complex-and-periodontal-ligament-in-transplantation-with-stem-cell-conditioned-medium
#3
JOURNAL ARTICLE
Shintarou Sakatoku, Yuki Hayashi, Taku Futenma, Yoshihiko Sugita, Ryo Ishizaka, Hiroyuki Nawa, Koichiro Iohara
PURPOSE: The microenvironment is required for tissues to maintain their properties in vivo . This microenvironment encompasses the types and three-dimensional arrangement of cells forming the tissues, and their interactions with neighboring cells and extracellular matrices, as represented by the stem cell niche. Tissue regeneration depends not on the original tissue source of the transplanted cells, but on the microenvironment in which they are transplanted. We have previously reported pulp regeneration in a heterotopic root graft model by transplantation of conditioned medium alone, which suggests that host-derived cells expressing receptors for migration factors in conditioned medium migrate into the root canal and cause pulp regeneration...
2024: Stem Cells International
https://read.qxmd.com/read/38390035/different-levels-of-autophagy-activity-in-mesenchymal-stem-cells-are-involved-in-the-progression-of-idiopathic-pulmonary-fibrosis
#4
REVIEW
Hongxia Tao, Qin Lv, Jing Zhang, Lijuan Chen, Yang Yang, Wei Sun
Idiopathic pulmonary fibrosis (IPF) is an age-related lung interstitial disease that occurs predominantly in people over 65 years of age and for which there is a lack of effective therapeutic agents. It has demonstrated that mesenchymal stem cells (MSCs) including alveolar epithelial cells (AECs) can perform repair functions. However, MSCs lose their repair functions due to their distinctive aging characteristics, eventually leading to the progression of IPF. Recent breakthroughs have revealed that the degree of autophagic activity influences the renewal and aging of MSCs and determines the prognosis of IPF...
2024: Stem Cells International
https://read.qxmd.com/read/38343632/effects-of-extracellular-vesicles-derived-from-human-umbilical-cord-blood-mesenchymal-stem-cells-on-cell-immunity-in-nonobese-mice
#5
JOURNAL ARTICLE
Yang Ou, Yang Yang, Yan Wang, Heng Su, Yi-Kun Zhou
Autoimmune responses are the most important pathogenic mechanisms underlying type 1 diabetes (T1D). Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) have immunomodulatory effects. In this study, we investigated whether EVs derived from human umbilical cord MSCs (HucMSC-EVs) have treatment effects on nonobese diabetic (NOD) mice as model of T1D. HucMSC-EVs were isolated from human umbilical cord MSCs and characterized. NOD mice (aged 4 weeks) were administered with HucMSC-EVs or the same volume of phosphate-buffered saline (PBS) via caudal vein injection twice per week...
2024: Stem Cells International
https://read.qxmd.com/read/38328463/retracted-effect-of-fas-and-bcl-2-dna-damages-response-expression-in-stem-cells-on-apoptosis-of-nucleus-pulposus-of-intervertebral-disc
#6
Stem Cells International
[This retracts the article DOI: 10.1155/2023/8103595.].
2024: Stem Cells International
https://read.qxmd.com/read/38328462/retracted-loading-gentamicin-and-zn-2-on-tio-2-nanotubes-to-improve-anticoagulation-endothelial-cell-growth-and-antibacterial-activities
#7
Stem Cells International
[This retracts the article DOI: 10.1155/2021/9993247.].
2024: Stem Cells International
https://read.qxmd.com/read/38328461/retracted-human-umbilical-mesenchymal-stem-cells-derived-microvesicles-attenuate-formation-of-hypertrophic-scar-through-multiple-mechanisms
#8
Stem Cells International
[This retracts the article DOI: 10.1155/2023/9125265.].
2024: Stem Cells International
https://read.qxmd.com/read/38323168/stem-cell-derived-organoids
#9
EDITORIAL
Yujing Li, Xuekun Li, Yunhee Kang, Shu Jiang
No abstract text is available yet for this article.
2024: Stem Cells International
https://read.qxmd.com/read/38298242/retracted-adipose-derived-mesenchymal-stem-cell-derived-extracellular-vesicles-rescue-tendon-injury-in-rat-via-the-mir-19-a-igfbp3-axis
#10
Stem Cells International
[This retracts the article DOI: 10.1155/2022/4197473.].
2024: Stem Cells International
https://read.qxmd.com/read/38298241/retracted-long-noncoding-rna-sammson-promotes-melanoma-progression-by-inhibiting-foxa2-expression
#11
Stem Cells International
[This retracts the article DOI: 10.1155/2023/8934210.].
2024: Stem Cells International
https://read.qxmd.com/read/38298240/retracted-the-role-of-tams-in-tumor-microenvironment-and-new-research-progress
#12
Stem Cells International
[This retracts the article DOI: 10.1155/2022/5775696.].
2024: Stem Cells International
https://read.qxmd.com/read/38298239/retracted-mfg-e8-exerts-neuroprotection-in-neural-stem-cells-induced-by-anesthetic-sevoflurane-via-regulating-the-pi3k-akt-pathways
#13
Stem Cells International
[This retracts the article DOI: 10.1155/2022/5609501.].
2024: Stem Cells International
https://read.qxmd.com/read/38298238/retracted-a-pan-cancer-analysis-of-the-role-of-pbrm1-in-human-tumors
#14
Stem Cells International
[This retracts the article DOI: 10.1155/2022/7676541.].
2024: Stem Cells International
https://read.qxmd.com/read/38298237/retracted-diminished-adipor1-appl1-interaction-mediates-reduced-cardioprotective-actions-of-adiponectin-against-myocardial-ischemia-reperfusion-injury-in-type-2-diabetic-mice
#15
https://read.qxmd.com/read/38298236/retracted-mir-141-3p-targeted-sirt1-to-inhibit-osteogenic-differentiation-of-bone-marrow-mesenchymal-stem-cells
#16
Stem Cells International
[This retracts the article DOI: 10.1155/2023/9094092.].
2024: Stem Cells International
https://read.qxmd.com/read/38298235/retracted-correlation-analysis-between-chronic-osteomyelitis-and-bacterial-biofilm
#17
Stem Cells International
[This retracts the article DOI: 10.1155/2022/9433847.].
2024: Stem Cells International
https://read.qxmd.com/read/38298234/retracted-usp21-promotes-the-progression-of-nasopharyngeal-carcinoma-by-regulating-foxm1
#18
Stem Cells International
[This retracts the article DOI: 10.1155/2023/9196583.].
2024: Stem Cells International
https://read.qxmd.com/read/38298233/retracted-extracellular-vesicles-derived-from-lung-cancer-cells-induce-transformation-of-normal-fibroblasts-into-lung-cancer-associated-fibroblasts-and-promote-metastasis-of-lung-cancer-by-delivering-lncrna-hotair
#19
https://read.qxmd.com/read/38298232/retracted-mir-125b-5p-stat3-axis-regulates-drug-resistance-in-osteosarcoma-cells-by-acting-on-abc-transporters
#20
Stem Cells International
[This retracts the article DOI: 10.1155/2023/9997676.].
2024: Stem Cells International
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