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Journal of Geriatric Oncology

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https://read.qxmd.com/read/30772191/potentially-inappropriate-medication-use-and-associated-healthcare-utilization-and-costs-among-older-adults-with-colorectal-breast-and-prostate-cancers
#1
Xue Feng, Gerald M Higa, Fnu Safarudin, Usha Sambamoorthi, Xi Tan
OBJECTIVES: To assess the association between Potentially Inappropriate Medication (PIM) use and healthcare utilization and costs among Medicare beneficiaries with breast, prostate, or colorectal cancer. MATERIALS AND METHODS: A retrospective cohort study was conducted using the SEER-Medicare linked database in older adults with breast (N = 17,630), prostate (N = N = 18,721), or colorectal cancer (female: N = 5652; male: N = 3768). PIM use was defined based on 2015 Beers Criteria and was measured using prescription claims...
February 13, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30765269/improving-cancer-research-in-older-adults-the-uk-national-cancer-research-institute-initiative
#2
EDITORIAL
Richard Simcock
No abstract text is available yet for this article.
February 11, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30765268/association-of-multidimensional-comorbidities-with-survival-toxicity-and-unplanned-hospitalizations-in-older-adults-with-metastatic-colorectal-cancer-treated-with-chemotherapy
#3
Ki Hyang Kim, Jae Jin Lee, Jongphil Kim, Jun-Min Zhou, Fabio Gomes, Marina Sehovic, Martine Extermann
BACKGROUND: Studies of older patients with colorectal cancer(CRC) have found inconsistent results about the correlation of various comorbidities with overall survival(OS) and treatment tolerance. To refine our understanding, we evaluated this correlation using the Cumulative Illness Rating Scale-Geriatric(CIRS-G) and heat maps to identify subgroups with the highest impact. METHODS: We retrospectively reviewed 153 patients aged 65 years and older with stage IV CRC undergoing chemotherapy...
February 11, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30745117/preoperative-geriatric-assessment-and-follow-up-of-patients-older-than-75-years-undergoing-elective-surgery-for-suspected-colorectal-cancer
#4
Katja Schubert Samuelsson, Monika Egenvall, Inga Klarin, Johan Lökk, Ulf Gunnarsson
OBJECTIVES: We investigated the predictive value of specific tools used in a Comprehensive Geriatric Assessment (CGA) with regard to postoperative outcome in patients 75 years and older undergoing elective colorectal cancer (CRC) surgery. Furthermore, recovery was followed over the first postoperative year using the same assessment tools. MATERIAL AND METHODS: Baseline clinical and CGA variables including functional and nutritional status, pressure sore risk, fall risk, cognition, depression, polypharmacy, comorbidity, and health-related quality-of-life (HRQoL) were prospectively recorded...
February 7, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30745116/from-clinical-trials-to-real-world-practice-immune-checkpoint-inhibitors-in-older-adults
#5
EDITORIAL
Kah Poh Loh, Melisa L Wong, Ronald Maggiore
No abstract text is available yet for this article.
February 7, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30733001/chronic-cardiovascular-toxicity-in-the-older-oncology-patient-population
#6
REVIEW
Simon G Findlay, Jason H Gill, Ruth Plummer, Carol DeSantis, Chris Plummer
Survivorship statistics demonstrate that the incidence of cancer continues to rise worldwide, with a further 60% increase in diagnoses predicted by 2030 attributed to lifestyle risk factors, screening programmes resulting in earlier diagnosis but also the changing demographics of the population. More than a third of new cancer diagnoses and almost half of cancer survivors are now aged 70 years or older. Despite this increasing incidence, worldwide five-year cancer survival rates have improved significantly over the past two decades...
February 5, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30718180/disparities-in-broad-based-genomic-sequencing-for-patients-with-advanced-non-small-cell-lung-cancer
#7
LETTER
Fauzia Riaz, Carolyn J Presley, Anne C Chiang, Janina A Longtine, Pamela R Soulos, Kerin B Adelson, Roy S Herbst, Nathan C Nussbaum, Rachael A Sorg, Amy P Abernethy, Vineeta Agarwala, Cary P Gross
No abstract text is available yet for this article.
February 1, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30718179/special-issue-to-honor-and-remember-dr-arti-hurria-call-for-papers-for-the-journal-of-geriatric-oncology
#8
EDITORIAL
Supriya Gupta Mohile, William Dale, Siri Rostoft
No abstract text is available yet for this article.
February 1, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30709612/mortality-by-a-proxy-performance-status-as-defined-by-a-claims-based-measure-for-disability-status-in-older-patients-with-newly-diagnosed-multiple-myeloma-in-the-united-states
#9
Shuling Li, Tanya Natwick, Jiannong Liu, Vicki A Morrison, Sarah Vidito, Winifred Werther, Akeem A Yusuf, Saad Z Usmani
OBJECTIVES: We applied a claims-based definition of disability status as a proxy for performance status (PS) and examined associations between PS and mortality in a population-based cohort of older US adults with multiple myeloma (MM). MATERIALS AND METHODS: We identified older (≥66 years) Medicare beneficiaries diagnosed with MM January 1, 2008-December 31, 2011, who began first-line therapy in the study period (through December 31, 2012). We estimated predicted probability of poor PS for each patient at initiation of each line up to fourth-line therapy, classified as poor (predicted probability ≥0...
January 29, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30692020/survival-benefit-of-statins-in-older-patients-with-rectal-cancer-a-swedish-population-based-cohort-study
#10
Angeliki Kotti, Annica Holmqvist, Maria Albertsson, Xiao-Feng Sun
OBJECTIVES: Increasing evidence suggests that statins may have antitumor effects but their role in rectal cancer appears inconclusive. The aim of this study was to investigate whether statins may have an impact on survival of older and younger patients with rectal cancer. MATERIALS AND METHODS: This study included 238 patients ≥70 years and 227 patients <70 years old, from the Southeast Health Care Region of Sweden, who were diagnosed with rectal adenocarcinoma between 2004 and 2013...
January 25, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30686679/prevalence-of-pain-in-patients-with-cancer-aged-70-years-or-older-a-prospective-observational-study
#11
Antonella Brunello, Selma Ahcene-Djaballah, Annunziata Lettiero, Giuseppina Tierno, Pasquale Fiduccia, Irene Guglieri, Vincenzo Dadduzio, Marco Maruzzo, Stefania Schiavon, Sara Lonardi, Vittorina Zagonel
BACKGROUND: Pain is a common symptom among patients with cancer, yet pain prevalence and management in older cancer pts. are poorly known. METHODS: Patients aged ≥70 years referred to Istituto Oncologico Veneto IRCCS from January 2011 to December 2013 were evaluated with Comprehensive Geriatric Assessment (CGA). Pain was assessed by means of short form of McGill Pain Questionnaire (MPQ-sf), Brief Pain Inventory (BPI-sf), and numerical rating scale (NRS). Pts with completed CGA, no severe cognitive impairment and completed pain assessment were enrolled...
January 24, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30674419/challenges-of-treatment-selection-in-the-older-prostate-patient
#12
LETTER
Alberto Carretero González, María Cruz Martín, Marianne Luyo, Daniel Castellano, Guillermo de Velasco
No abstract text is available yet for this article.
January 20, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30665876/using-wearables-to-screen-motor-performance-deterioration-because-of-cancer-and-chemotherapy-induced-peripheral-neuropathy-cipn-in-adults-toward-an-early-diagnosis-of-cipn
#13
Mohsen Zahiri, Kevin M Chen, He Zhou, Hung Nguyen, Biruh T Workeneh, Sarvari V Yellapragada, Yvonne H Sada, Michael Schwenk, Bijan Najafi
OBJECTIVE: An essential component for optimizing quality of life in adults with cancer is determining the degree to which therapy may negatively impact motor-performance, so that patients can maintain their quality of life and independence. This study examined whether instrumented gait and balance could determine the magnitude of deterioration in motor-performance from chemotherapy-induced peripheral neuropathy (CIPN). METHODS: We recruited 84 adults with cancer (age = 71...
January 18, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30665875/secondary-hematologic-malignancies-with-poly-adenosine-diphosphate-ribose-polymerase-inhibitors-is-the-buzz-real-insights-from-a-meta-analysis-of-phase-3-randomized-controlled-trials
#14
LETTER
Somedeb Ball, Anita Sultan, Myo H Zaw, Kyaw Z Thein
No abstract text is available yet for this article.
January 18, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30661877/short-term-postoperative-physical-decline-and-patient-reported-recoveryin-people-aged-70-or-older-undergoing-abdominal-cancer-resection-a-prospective-cohort-study
#15
Emelie Karlsson, Erika Franzén, Malin Nygren-Bonnier, Mia Bergenmar, Elisabeth Rydwik
OBJECTIVES: Extensive physical deterioration as a consequence of both cancer and surgical treatment can lead to increased care needs and decreased well-being. Information on short-term physical decline and patient-reported recovery in older patients undergoing abdominal cancer surgery is still sparse. We aimed to describe the short-term changes and study the associations between preoperative physical performance and postoperative mobility, as well as patient-reported recovery in this patient group...
January 17, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30661876/long-term-survival-estimates-in-older-patients-with-pathological-stage-i-gastric-cancer-undergoing-gastrectomy-duocentric-analysis-of-simplified-scoring-system
#16
Katsunobu Sakurai, Naoshi Kubo, Yutaka Tamamori, Tatsuro Tamura, Takahiro Toyokawa, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kiyoshi Maeda, Yukio Nishiguchi, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: Our aim was to determine factors predictive of long-term post-gastrectomy outcomes in older adults with pathological stage I gastric cancer (GC). METHODS: A total of 175 patients with resected pathological stage I GC at two institutions were reviewed, each ≥75 years old at the time of gastrectomy and full participants in a 5-year follow-up program. The procedures were undertaken between January 2006 and December 2011. Patients were divided into two groups: survivors and non-survivors at postoperative Year 5...
January 17, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30661875/geriatric-hematology-research-presented-at-the-2018-american-society-of-hematology-annual-meeting-young-international-society-of-geriatric-oncology-perspective-paper
#17
Kah Poh Loh, Konstantinos Christofyllakis, Li-Wen Huang, Alice Mims
No abstract text is available yet for this article.
January 17, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30660501/perspectives-on-geriatric-oncology-research-presented-at-the-2018-san-antonio-breast-cancer-symposium
#18
Nicolò Matteo Luca Battisti, Allison Magnuson, Mina S Sedrak, Enrique Soto-Perez-de-Celis
No abstract text is available yet for this article.
January 16, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30639266/the-added-value-of-an-assessment-of-the-patient-s-hand-grip-strength-to-the-comprehensive-geriatric-assessment-in-g8-abnormal-older-patients-with-cancer-in-routine-practice
#19
Michelle Lycke, Lore Ketelaars, Evi Martens, Tessa Lefebvre, Hans Pottel, Koen Van Eygen, Lieselot Cool, Lies Pottel, Cindy Kenis, Patricia Schofield, Tom Boterberg, Philip R Debruyne
OBJECTIVES: A comprehensive geriatric assessment (CGA) is the key treatment approach to guide decisions in older patients with cancer. In this paper, the added value of an assessment of the patient's hand grip strength to predict survival in patients with an abnormal G8-questionnaire (G8) score is investigated. MATERIALS AND METHODS: Patients were screened by the G8, followed by a CGA in case of an abnormal screening (≤14.0). Hand grip strength was assessed by use of the JAMAR® hydraulic hand dynamometer...
January 10, 2019: Journal of Geriatric Oncology
https://read.qxmd.com/read/30639265/should-we-involve-patients-more-actively-perspectives-of-the-multidisciplinary-team-on-shared-decision-making-for-older-patients-with-metastatic-castration-resistant-prostate-cancer
#20
Isabel B de Angst, Paul J M Kil, Chris H Bangma, Johanna J M Takkenberg
OBJECTIVE: To evaluate perspectives of the multidisciplinary team concerning shared decision-making (SDM) in treatment decisions for older patients with metastatic castration-resistant prostate cancer (mCRPC). MATERIALS AND METHODS: A survey among Dutch healthcare providers was conducted to assess healthcare providers' perspectives on patient involvement in decision-making and the value of a decision aid (DA) in the decision-making process. Treatment recommendations were assessed using hypothetical cases in which providers were asked to evaluate their likelihood of pursuing listed treatment options...
January 10, 2019: Journal of Geriatric Oncology
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