Suncheol Heo, Jae Yong Yu, Eun Ae Kang, Hyunah Shin, Kyeongmin Ryu, Chungsoo Kim, Yebin Chegal, Hyojung Jung, Suehyun Lee, Rae Woong Park, Kwangsoo Kim, Yul Hwangbo, Jae-Hyun Lee, Yu Rang Park
OBJECTIVES: The objective of this study was to develop and validate a multicenter-based, multi-model, time-series deep learning model for predicting drug-induced liver injury (DILI) in patients taking angiotensin receptor blockers (ARBs). The study leveraged a national-level multicenter approach, utilizing electronic health records (EHRs) from six hospitals in Korea. METHODS: A retrospective cohort analysis was conducted using EHRs from six hospitals in Korea, comprising a total of 10,852 patients whose data were converted to the Common Data Model...
July 2023: Healthcare Informatics Research