Fatih Ceran, Ozgur Pilanci, Asuman Ozel, Gul Ilbay, Rukiye Karabacak, Mehmet Kanter, Konuralp Ilbay, Samet Vasfi Kuvat
BACKGROUND: In patients with nerve tissue defects, the use of autologous nerve grafts is the standard method of treatment. Alternatives to autologous, nerve grafts have attracted the attention of reconstructive surgeons. In this study, the results of nerve repairs using acellular dermal matrix (ADM) in an experimental rat sciatic nerve defect model are presented. METHODS: Thirty-six Sprague-Dawley rats were randomized into 5 groups: Group 1: control group, Group 2: negative control group ( n = 6), Group 3: autologous nerve graft group ( n = 10), Group 4: donor site entubulated with ADM group ( n = 10); and Group 5: nerve graft entubulated with ADM group ( n = 10)...
December 8, 2022: Journal of Plastic Surgery and Hand Surgery