Farima Dalaei, Amar Bucan, Alexander Wiinholt, Mads Gustaf Jørgensen, Christian Rønn Hansen, Christina Baun, Svend Hvidsten, Eva Kildall Hejbøl, Henrik Daa Schrøder, Jens Ahm Sørensen
Lymphedema is a common complication following breast cancer treatment with axillary lymphadenectomy and radiotherapy. Currently, there is no curative treatment for this disease, hence there is a need for new therapeutic suggestions. The aim of this study was to investigate the effect of hyaluronidase (HYAL) injections after inducing hindlimb lymphedema in 36 female C57BL/6 mice. HYAL injections were administered every second day for 14 days in three groups: (1) HYAL for 1 week followed by saline for 1 week, (2) HYAL for 2 weeks, and (3) saline injections for 2 weeks...
June 20, 2023: Journal of Plastic Surgery and Hand Surgery