journal
https://read.qxmd.com/read/38883669/lung-abscess-the-non-conservative-management-a-narrative-review
#21
REVIEW
Walid Hadid, Giulia Maria Stella, Ashish P Maskey, Rabih I Bechara, Shaheen Islam
BACKGROUND AND OBJECTIVE: Systemic antibiotics are the best treatment options for lung abscesses. However, up to 37% of lung abscesses do not respond to antibiotics and may require additional interventions. Percutaneous transthoracic tube drainage (PTTD), endoscopic catheter drainage (ECD) and surgical resection are additional options available when first line therapy with systemic antibiotics are unsuccessful. In this narrative review, we summarize all available interventional procedures, techniques, complications, safety, and contraindications...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883668/analysis-of-related-factors-and-treatment-effect-of-chylothorax-after-lung-surgery
#22
JOURNAL ARTICLE
Xingyu Zhu, Xiangwei Feng, Zhengwei Huang, Wangjue Xu, Aotian Guo, Jingwei Xu, Zhao Chen, Tao Shen, Jiayu Zhou, Zhengfu He
BACKGROUND: Chylothorax is a seldom encountered complication following lung surgery. However, due to the widespread practice of lung surgery, postoperative complications have inevitably arisen. Chylothorax significantly affects a patient's discharge and recovery. This study investigates the risk factors for postoperative chylothorax at our center and analyzes various treatment modalities and prognostic outcomes. METHODS: A retrospective analysis was conducted on all postoperative lung resections performed between January 2018 to August 2021 that met the inclusion criteria...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883667/feasibility-of-the-modified-mini-bronchoalveolar-lavage-techniques-using-a-nasogastric-suction-catheter-and-polytetrafluoroethylene-bronchoscopic-suction-catheter-in-diagnosing-bilateral-pneumonia-a-pilot-study
#23
JOURNAL ARTICLE
Phongsaphat Pojpanichphong, Nadwipa Yuangtrakul
BACKGROUND: The adequacy of actual lower respiratory tract samples collected using the current collection technique is debated. Endotracheal aspiration is commonly insufficient and can be contaminated with colonization from the proximal airway. Diagnostic bronchoscopy is the standard method for collecting specimens from the lower respiratory tract. However, it is usually unavailable in resource-limited settings. At present, noninvasive methods with the mini-bronchoalveolar lavage (BAL) catheter are used to collect specimens from the lower respiratory tract...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883666/complement-activation-is-associated-with-right-ventricular-dysfunction-and-the-severity-of-pulmonary-embolism-links-with-prothrombotic-state
#24
JOURNAL ARTICLE
Paweł Rostoff, Michał Ząbczyk, Joanna Natorska, Anetta Undas
BACKGROUND: Little is known about the role of complement activation in acute pulmonary embolism (PE). We investigated whether complement activation is associated with the severity of acute PE, along with the associated prothrombotic state, systemic inflammation and neutrophil extracellular traps (NETs) formation. METHODS: We studied 109 normotensive, non-cancer PE patients (aged 58.1±15.0 years). On admission prior to initiation of anticoagulation, plasma soluble complement components, i...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883665/association-between-anion-gap-and-the-30-day-mortality-of-patients-with-ventilator-associated-pneumonia-a-study-of-the-mimic-iii-database
#25
JOURNAL ARTICLE
Hui Yu, Sheng Chen
BACKGROUND: Serum anion gap (AG) can potentially be applied to the diagnosis of various metabolic acidosis, and a recent study has reported the association of AG with the mortality of patients with coronavirus disease 2019 (COVID-19). However, the relationship of AG with the short-term mortality of patients with ventilator-associated pneumonia (VAP) is still unclear. Herein, we aimed to investigate the association between AG and the 30-day mortality of VAP patients, and construct and assess a multivariate predictive model for the 30-day mortality risk of VAP...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883664/clinical-outcomes-of-the-type-ii-hybrid-procedure-for-the-repair-of-extensive-aortic-arch-pathology
#26
JOURNAL ARTICLE
Yuan Xue, Yeting Lou, Xiaomeng Wang, Shipan Wang, Yue Shi, Duanduan Chen, Giovanni Mariscalco, Ioannis Dimarakis, Haiyang Li, Hongjia Zhang
BACKGROUND: Type II hybrid arch repair (HAR) has been used for the repair of extensive aortic arch pathology. The aim of this study was to retrospectively analyze single-stage hybrid treatment involving replacement of the ascending aorta, arch debranching, and zone 0 stent graft deployment. METHODS: We retrospectively analyzed clinical data from 41 patients with acute and chronic aortic disease who underwent a type II hybrid arch procedure at Beijing Anzhen Hospital and Beijing Chaoyang Hospital from January 2020 to August 2022...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883663/the-evolving-field-of-sublobar-resection-in-search-of-the-optimal-operation-or-the-optimal-definition
#27
EDITORIAL
Luis J Herrera, Kojo Dadzie
No abstract text is available yet for this article.
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883662/multimodal-prehabilitation-in-patients-with-non-small-cell-lung-cancer-a-feasibility-study
#28
JOURNAL ARTICLE
David W G Ten Cate, Rosaline van den Berg, Maaike Scholten-Bakker, Charlotte J L Molenaar, Erik M von Meyenfeldt, Gerrit D Slooter, Frank J C van den Broek, Geertruid M H Marres
BACKGROUND: Anatomic pulmonary resection is the preferred curative treatment in operable non-small cell lung cancer (NSCLC) but is associated with postoperative complications and inevitable compromise in functional capacity. Preoperative enhancement of functional capacity can be achieved with prehabilitation, yet the window of opportunity in NSCLC patients is small because patients are required to undergo surgery within 3 weeks from diagnosis. The goal of this study was to assess the feasibility of a prehabilitation programme in NSCLC within a 3-week timeframe and its effect on functional capacity-although the study was not powered to confirm improvements in functional capacity...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883661/intraprocedural-computed-tomography-guided-navigation-with-ventilatory-strategy-for-atelectasis-icnva-a-modified-electromagnetic-navigation-bronchoscopy
#29
JOURNAL ARTICLE
Shaohua Dai, Guoqiu Xu, Zhiguo Chen, Jian Tang
BACKGROUND: Computed tomography (CT)-body divergence limits the accuracy of electromagnetic navigation bronchoscopy (ENB) in peripheral lung lesions diagnosis. We developed intraprocedural CT-guided navigation with ventilatory strategy for atelectasis (ICNVA) ENB for patients with peripheral lung lesions. METHODS: Retrospective observational study in which ten consecutive patients with pulmonary lesions (without bronchial direct connection) underwent ICNVA-ENB was conducted...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883660/post-thoracotomy-pain-syndrome-in-the-era-of-minimally-invasive-thoracic-surgery
#30
REVIEW
Takuro Miyazaki, Ryoichiro Doi, Keitaro Matsumoto
Post-thoracotomy pain syndrome (PTPS) is defined as pain around the wound that persists for more than 2 months after surgery. Persistent pain not only increases the use of analgesics and their side effects but also causes many social problems, such as decreased activities of daily living, decreased quality of life, and increased medical costs. In particular, thoracic surgery is associated with a higher frequency and severity of chronic pain than is surgery for other diseases. The basic principles of postoperative pain treatment, not limited to thoracic surgery, are multimodal analgesic methods (using combinations of several drugs to minimize opioid use) and around-the-clock treatment (administering analgesics at a fixed time and in sufficient doses)...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883659/somatic-kmt2d-loss-of-function-mutations-in-lung-squamous-cell-carcinoma-a-single-center-cohort-study
#31
JOURNAL ARTICLE
Zekui Fang, Xiping Wu, Li Xiao, Chunli Wang, Yanyan Zhao, Qingchao Zhang, Paola Anna Jablonska, Alonso La Rosa, Wolfram C M Dempke, Muhammad Furqan, Huizhen Fan
BACKGROUND: The significant progress has been made in targeted therapy for lung adenocarcinoma (LUAD) in the past decade. Only few targeted therapeutics have yet been approved for the treatment of lung squamous cell carcinoma (LUSC). Several higher frequency of gene alterations are identified as potentially actionable in LUSC. Our work aimed to explore the complex interplay of multiple genetic alterations and pathways contributing to the pathogenesis of LUSC, with a very low frequency of a single driver molecular alterations to develop more effective therapeutic strategies in the future...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883658/thoracic-cavity-remodeling-and-pulmonary-function-change-after-chest-wall-resection
#32
JOURNAL ARTICLE
Seon Yong Bae, Ji Hyeon Park, Bubse Na, Kwon Joong Na, Samina Park, In Kyu Park, Chang Hyun Kang, Young Tae Kim
BACKGROUND: Chest wall resection (CWR) is an essential procedure for treating malignancies and infectious conditions of the chest wall. However, there are few studies on the pulmonary function and changes in thoracic cavity volume (TCV) related to CWR. This study aims to investigate the effects of CWR on long-term changes in TCV and pulmonary function. METHODS: Data of patients who underwent CWR between 2001 and 2021 were retrospectively reviewed. Patients who underwent single rib or lung resection rather than wedge resection were excluded...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883657/let-s-think-outside-of-the-box
#33
EDITORIAL
Paula Duarte D'Ambrosio, Juliana Ferreira, C Isabela Silva Muller, Paula Antonia Ugalde Figueroa
No abstract text is available yet for this article.
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883656/performance-verification-of-a-biochemical-detection-system-for-hydrothorax-and-ascites-and-clinical-diagnostic-accuracy-evaluation-of-exudate-and-tuberculous-effusion
#34
JOURNAL ARTICLE
Junyuan Huang, Pinning Feng, Yongjiang Chen, Xi Li, Iyare Izevbaye, Weiguo Lu, Yingchun Zhou
BACKGROUND: Lactate dehydrogenase (LDH), total protein (TP) and glucose (Glu) in pleural hydrothorax and ascites can be used in the diagnosis of exudate, and adenosine deaminase (ADA) can be used in the diagnosis of tuberculous effusion. However, the manufacturers do not claim that their biochemical reagents can be used to detect hydrothorax and ascites samples. Therefore, medical laboratories must conduct suitability studies on biochemical reagents for hydrothorax and ascites samples to comply with regulatory requirements for humor detection...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883655/development-of-neuromodulation-for-atrial-fibrillation-a-narrative-review
#35
REVIEW
Ning Yang, Yang Zou, Bohan Wen, Yingman Wang, Ju Mei, Zhaolei Jiang
BACKGROUND AND OBJECTIVE: Atrial fibrillation (AF) is a prevalent clinical arrhythmia with a high incidence of disability and mortality. Autonomic nervous system (ANS) plays a crucial role in the onset and persistence of AF, and can lead to electrophysiological changes and alterations in atrial structure. Both animal models and clinical findings suggest that parasympathetic and sympathetic activity within the cardiac ANS could induce atrial remodeling and AF. Remodeling of the cardiac autonomic nerves is a significant structural basis for promoting AF...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883654/value-of-computed-tomography-radiomics-combined-with-inflammation-indices-in-predicting-the-efficacy-of-immunotherapy-in-patients-with-locally-advanced-and-metastatic-non-small-cell-lung-cancer
#36
JOURNAL ARTICLE
Hancheng Shao, Jun Zhu, Liang Shi, Jie Yao, Yuxuan Wang, Chonggang Ma, Andrzej Swierniak, Bin Ni
BACKGROUND: Although immunotherapy has revolutionized the treatment landscape of lung cancer and improved the prognosis of this malignancy, many patients with lung cancer still are not able to benefit from it because of many different reasons. The expression of programmed death ligand-1 (PD-L1) in tumor cells has been approved for the prediction of immunotherapy efficacy; however, its clinical application has been limited by the invasiveness of PD-L1 determination and the heterogeneity of tumor cells...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883653/regional-trends-in-diagnosis-of-advanced-lung-cancer-in-michigan-over-33-years
#37
JOURNAL ARTICLE
Hollis E Hutchings, Sue C Grady, Qiong Zhang, Erik Schwarze, Andrew Popoff, Kamil Khanipov, Ikenna C Okereke
BACKGROUND: Lung cancer is the most common cancer killer worldwide. Nearly 80 percent of lung cancers are diagnosed at advanced stages. Lack of access to medical care and undwerutilized lung cancer screening are key reasons for advanced diagnoses. We sought to understand the regional differences in presentation of lung cancer across Michigan. Utilizing a comprehensive cancer registry over 33 years, our goal was to examine associations between sociodemographic patient factors and diagnoses at advanced stages...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883652/intrapleural-minocycline-pleurodesis-for-bilateral-pneumothorax-due-to-septic-pulmonary-embolism-a-case-report
#38
JOURNAL ARTICLE
Masahiro Yanagiya, Yoshihiro Kazama, Shun-Mao Yang, Amos Lal, Debora Russo, Satoshi Watanabe, Ami Wada, Yoshiaki Furuhata, Jun Nakajima
BACKGROUND: Pneumothorax is a rare but serious complication of septic pulmonary embolism (SPE). SPE is a life-threatening disorder wherein infected thrombi bring infarction of the terminal and small caliber parts of the pulmonary vasculature and develop multiple nodular and cavitary lesions. Interventions other than conservative chest tube drainage for pneumothorax due to SPE have rarely been reported. Here, we present a case of bilateral pneumothorax due to SPE treated with intrapleural minocycline pleurodesis...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883651/indeterminate-pulmonary-nodules-and-prior-malignancy-survival-and-recurrence-after-surgery-in-newly-diagnosed-stage-i-non-small-cell-lung-cancer
#39
JOURNAL ARTICLE
José Franco, Genaro Galán, Elvira Bondía, Irene Pastor, Andrea Calderón, Amelia Insa, Miguel Á Mollá, Paloma Martín-Martorell, Juan A Carbonell, Jaime Signes-Costa
BACKGROUND: Surgical excision biopsy remains the only reliable option in most cases of indeterminate pulmonary nodules, particularly in cancer survivors for whom surgery provides local control of pulmonary metastasis and the best chance of cure for early-stage lung cancer. Nevertheless, unnecessary surgeries remain a concern and the prognosis of newly diagnosed lung cancer might be influenced by the history of previous malignancy. We aimed to analyze the outcomes of resected indeterminate pulmonary nodules in patients with and without previous malignancy, and the impact of prior cancer history on survival and recurrence in stage I non-small cell lung cancer (NSCLC) patients...
May 31, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38883650/interest-of-the-leicester-cough-questionnaire-in-predicting-postoperatives-complications-after-lung-resection-lcq-surge
#40
JOURNAL ARTICLE
Caroline Corbice, André Gillibert, François-Régis Sarhan, Mathieu Sarsam, Jean Selim, Benjamin Bottet, Jean-Marc Baste, Fairuz Boujibar
BACKGROUND: Postoperative complications may occur after major lung surgery for non-small cell lung cancer (NSCLC), with a high rate of morbidity and mortality. The main objective of this study was to assess the relevance of preoperative Leicester Cough Questionnaire (LCQ) to predict postoperative complications after major lung resection for any indication. METHODS: This was a retrospective cohort study conducted in the Thoracic Surgery Department of Rouen University Hospital from November 21st, 2022, to June 2nd, 2023...
May 31, 2024: Journal of Thoracic Disease
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