Chin Heng Fong, Nicholas Meti, Timothy Kruser, Jessica Weiss, Zhihui Amy Liu, Hirokazu Takami, Yoshitaka Narita, Fabio Ynoe de Moraes, Archya Dasgupta, Choo Khoon Ong, James C H Yang, Jih Hsiang Lee, Natalya Kosyak, Nicholas Pavlakis, Paul Kongkham, Mark Doherty, Natasha B Leighl, David B Shultz
BACKGROUND: The role for radiotherapy or surgery in the upfront management of brain metastases (BrM) in epidermal growth factor receptor mutant ( EGFR m) or anaplastic lymphoma kinase translocation positive ( ALK +) non-small cell lung cancer (NSCLC) is uncertain because of a lack of prospective evidence supporting tyrosine kinase inhibitor (TKI) monotherapy. Further understanding of practice heterogeneity is necessary to guide collaborative efforts in establishing guideline recommendations...
August 31, 2023: Journal of Thoracic Disease