journal
https://read.qxmd.com/read/36910122/anatomic-lung-resection-after-immune-checkpoint-inhibitors-for-initially-unresectable-advanced-staged-non-small-cell-lung-cancer-a-retrospective-cohort-analysis
#1
JOURNAL ARTICLE
Harry Etienne, Ludovic Fournel, Pierre Mordant, Bertrand Richard Delatour, Karel Pfeuty, Gil Frey, Agathe Seguin-Givelet, Alex Fourdrain, Christophe Lancelin, Pascal Berna, Antoine Legras, Marco Alifano, Patrick Bagan, Jalal Assouad
BACKGROUND: Patients with initially unresectable advanced non-small cell lung cancer (NSCLC) might experience prolonged responses under immune checkpoint inhibitors (ICIs). In this setting, Multidisciplinary Tumor Board (MTB) seldomly suggest surgical resection of the primary tumor with the ultimate goal to eradicate macroscopic residual disease. Our objective was to report the perioperative outcomes of patients who underwent anatomic lung resection in these infrequent circumstances. METHODS: We set a retrospective multicentric single arm study, including all patients with advanced-staged initially unresectable NSCLC (stage IIIB to IVB) who received systemic therapy including ICIs and eventually anatomical resection of the primary tumor in 10 French thoracic surgery units from January 2016 to December 2020...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910121/medical-thoracoscopy-effective-cheap-and-safe-for-empyema
#2
COMMENT
Vinod Govindasaami
No abstract text is available yet for this article.
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910120/opioid-sparing-opportunities-in-the-thoracic-surgery-pathway
#3
EDITORIAL
Genevieve F Gilson, Sandeep J Khandhar
No abstract text is available yet for this article.
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910119/erratum-to-the-effects-of-hydrogen-treatment-in-a-cigarette-smoke-solution-induced-chronic-obstructive-pulmonary-disease-like-changes-in-an-animal-model
#4
(no author information available yet)
[This corrects the article DOI: 10.21037/jtd-22-324.].
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910118/the-effect-of-a-change-from-face-to-face-to-remote-positive-airway-pressure-education-for-patients-with-sleep-apnoea-during-the-coronavirus-disease-2019-pandemic-a-prospective-cohort-study
#5
JOURNAL ARTICLE
Imran Johan Meurling, Adam Birdseye, Rohan Gell, Eliza Sany, Richard Brown, Sean Higgins, Rexford Muza, David O'Regan, Guy Leschziner, Joerg Steier, Ivana Rosenzweig, Panagis Drakatos
BACKGROUND: The coronavirus disease-2019 (COVID-19) pandemic and national lockdowns necessitated a change in service delivery including positive airway pressure (PAP) education protocols, with no data on how this may impact subsequent PAP adherence. We aim to quantify adherence of PAP initiated during the COVID-19 pandemic and compare the effects of remote versus face-to-face (FTF) education in patients with obstructive sleep apnoea (OSA). METHODS: This prospective cohort study in a tertiary National Health Service (NHS) hospital sleep disorders centre in London, United Kingdom, included 141 patients aged >18 years with newly diagnosed OSA initiating PAP during the COVID-19 pandemic; 71 patients receiving standard FTF education compared to 70 patients educated on PAP remotely at the start of lockdown...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910117/immune-related-thyroid-dysfunction-is-associated-with-improved-long-term-prognosis-in-patients-with-non-small-cell-lung-cancer-treated-with-immunotherapy-a-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Zhengjun Li, Ying Xia, Mozhu Xia, Chang Liu, Tao Wang, Yongyu Liu, Yi Ren
BACKGROUND: Immunotherapy has changed the treatment landscape of lung cancer (LC), but its prognosis is still poor. Whether immunorelated thyroid dysfunction associated with the prognosis of LC patients remains controversial. We aimed to summarize the scientific evidence on whether thyroid dysfunction associated with immunotherapy for LC has a beneficial outcome on the survival of LC patients. METHODS: We searched the databases of MEDLINE and Embase for articles published until 31 December 2021 that quantified the impact on non-small cell lung cancer (NSCLC) patients' survival of immune-related thyroid dysfunction...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910116/suggested-robotic-assisted-thoracic-surgery-training-curriculum
#7
REVIEW
Muteb Al Zaidi, Gavin M Wright, Kazuhiro Yasufuku
Robotic-assisted surgery, a technological advancement in the field of surgery, has become increasingly popular among surgeons of many specialties over time. Robotic-assisted thoracic surgery (RATS) is comparable to video-assisted thoracic surgery (VATS) in terms of patient care outcomes; however, the perception of increased operative time and a lack of cost-effectiveness have led to controversy regarding its alleged benefits. Nevertheless, robotic surgery is one of the preferred options for minimally invasive surgery by some thoracic surgeon over VATS, due to its ability to provide 3-D vision, precise wrist movements, enhanced magnification, and instrument stability and articulation...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910115/laboratory-blood-test-profiling-reveals-distinct-biochemical-and-hemocyte-features-of-kras-mutated-non-small-cell-lung-cancer
#8
JOURNAL ARTICLE
Limin Ou, Xiuyu Cai, Wenchuang Zeng, Liyan Huang, Qiuhua Deng, Hailing Tang, Zhuxing Chen, Huan Zhou, Yongping Lin, Liping Liu, Wenhua Liang
BACKGROUND: The testing for capability of some routine blood test parameters to reflect the biology of non-small cell lung carcinoma with different driver mutations is of great interest and practice significance. We aim to screen these variables and, if allowed, develop a novel predictive model based on results of these routine blood tests commonly performed in clinical practice to inform which can help doctors assess the patient's genetic mutation status as early as possible before surgery...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910114/a-brief-appraisal-on-the-grade-methodology-and-the-development-of-recommendations-on-the-management-of-prolonged-air-leaks-by-the-palas-study-group
#9
EDITORIAL
Francesco Zaraca, Luca Bertolaccini
No abstract text is available yet for this article.
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910113/lung-cancer-with-air-lucency-a-systematic-review-and-clinical-management-guide
#10
REVIEW
Frank C Detterbeck, Ulas Kumbasar, Andrew X Li, Ami N Rubinowitz, Leah Traube, Babina Gosangi, Brooks V Udelsman, Brett C Bade, Sora Ely, Gaspar Barreto, Lynn T Tanoue, Edith M Marom, M Patricia Rivera
BACKGROUND: Lung cancers with air lucency are poorly understood, often recognized only after substantial progression. METHODS: From a systematic review (PubMed and EMBASE, 2000-2022, terms related to cystic, cavitary, bulla, pseudocavitary, bubble-like, date 10-30-2022) 49 studies were selected using broad inclusion criteria (case series of ≥10 cases up to trials and reviews). There was no source of funding. Primary evidence relevant to clinical management issues was assembled...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910112/incidence-and-diagnostic-validity-of-difficult-airway-in-emergency-departments-in-china-a-cross-sectional-survey
#11
JOURNAL ARTICLE
Yili Dai, Joseph Harold Walline, Yao Wu, Huadong Zhu, Jun Xu, Xuezhong Yu
BACKGROUND: The difficult airway is a topic of concern for any physician performing intubation. Severe adverse events which can happen because of an unexpected difficult airway emphasize the importance of prediction. This study aimed to investigate the incidence of difficult airways in emergency departments in mainland China and ascertain the predictive value of common assessment formulas. METHODS: This study was a multicentral, cross-sectional investigation of patients intubated in emergency departments in mainland China between March 1-30, 2021...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910111/the-association-of-coagulation-indicators-with-in-hospital-acute-kidney-injury-and-malignant-events-of-patients-with-acute-aortic-dissection-a-retrospective-cohort-study
#12
JOURNAL ARTICLE
Shiyan Jiang, Yinhua Li, Chenlin Li, Zhouwu Shu, Shiwan Wu, Xiaojia Lu, Yue Liu, Yinlong Deng, Yequn Chen, Peiwei Cai, Bin Wang
BACKGROUND: Acute kidney injury (AKI) is a prevalent complication of acute aortic dissection (AAD) and is associated with poor outcomes. The onset of AAD may result in endothelial injury due to the formation of the false lumen, which can activate the coagulation pathway and lead to coagulation dysfunction. It serves as a valuable diagnostic and prognostic marker for AAD, but also plays a role in the pathological mechanisms underlying AKI. We aimed to investigate the potential value of coagulation indicators at admission for assessing in-hospital AKI and malignant events after AAD...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910110/polymorphisms-in-the-fcer2-gene-have-associations-with-asthma-and-chronic-obstructive-pulmonary-disease
#13
JOURNAL ARTICLE
Zhoude Zheng, Jia Li, Yi Liu, Lun Li, Tingting Huang, Yilin Huang, Siyao Song, Jinming Gao
BACKGROUND: Asthma and chronic obstructive pulmonary disease (COPD) are heterogenetic diseases and exhibit many similarities. Dutch hypothesis proposed that these two diseases may have common genetic origins. This study aims to investigate whether asthma and COPD share a common genetic background in Chinese patients. METHODS: In this case-control study, single nucleotide polymorphisms (SNPs) were genotyped using SNaPshot. Haplotype disease analysis and haplotype phenotype analysis were applied to assess the relationship between three polymorphisms of the FCER2 gene and the risk of COPD/asthma...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910109/neoadjuvant-therapy-with-immunoagent-nivolumab-or-placebo-plus-chemotherapy-followed-by-surgery-and-adjuvant-treatment-in-subjects-with-resectable-esophageal-squamous-cell-carcinoma-study-protocol-of-a-randomized-multicenter-double-blind-phase-ii-trial-nation
#14
JOURNAL ARTICLE
Jun Yin, Siyun Lin, Yong Fang, Heng Jiao, Zongwei Chen, Han Tang, Jianmin Gu, Shaoyuan Zhang, Linyi Sun, Yin Li, Yongtao Han, Qixun Chen, Haiquan Chen, Zhigang Li, Lijie Tan
BACKGROUND: Neoadjuvant chemotherapy (nCT) has been the recommended treatment for locally advanced esophageal squamous cell carcinoma (ESCC). The addition of programmed cell death protein 1 (PD-1) inhibitor to nCT may improve oncologic outcome and survival. However, high-level evidence of neoadjuvant immunotherapy (nIT) combined with nCT in locally advanced resectable ESCC patients are still lacking. Hence, we describe this randomized controlled trial in order to assess the efficacy and safety of neoadjuvant nivolumab in combination with chemotherapy for locally advanced (stage II-III) ESCC patients...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910108/uniportal-vs-multiportal-thoracoscopic-segmentectomy-a-north-american-study
#15
JOURNAL ARTICLE
Ilitch Diaz-Gutierrez, Charles Antoine Menier, Félix H Savoie-White, Jesse E Doyle, Qi Wang, Rafael S Andrade, Paula Ugalde Figueroa
BACKGROUND: Uniportal video-assisted thoracoscopic surgery (VATS) segmentectomy is gaining worldwide acceptance, but experience in North America is still limited. We report a North American multicenter comparison of uniportal vs. multiportal VATS segmentectomy. METHODS: We performed an institutional review board-exempt retrospective chart review on prospectively collected databases at two North American centers, from January 2012 to December 2020. We included all VATS segmentectomy patients and excluded emergent cases (n=1), patients with incomplete records (n=2), and segmentectomy performed in conjunction with another type of lung resection (n=1)...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910107/beyond-the-limits-journey-to-feasible-and-safe-uniportal-vats-surgery-for-lung-cancer
#16
EDITORIAL
Mi Hyoung Moon
No abstract text is available yet for this article.
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910106/clinical-features-of-recurrent-spontaneous-pneumomediastinum
#17
JOURNAL ARTICLE
Hirotaka Kumeda, Gaku Saito, Takashi Eguchi, Daisuke Hara, Kimihiro Shimizu
BACKGROUND: Spontaneous pneumomediastinum recurrence is rare, and its clinical presentation is unclear. We investigated the clinical features of and predisposing factors for spontaneous pneumomediastinum recurrence. METHODS: We retrospectively investigated 30 consecutive patients treated for new-onset spontaneous pneumomediastinum at Shinshu Ueda Medical Center between 2012 and 2021. We evaluated the patient background characteristics, trigger activity, radiological findings, and clinical course of spontaneous pneumomediastinum, including those of recurrent cases...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910105/serum-vitamin-d-3-deficiency-can-affect-the-efficacy-of-sublingual-immunotherapy-in-children-with-allergic-rhinitis-a-retrospective-cohort-study
#18
JOURNAL ARTICLE
Liang Li, Xiaojian Cui, Xinjie Zhang, Lisheng Zheng, Xuyuan Sun, Cuihong Yang, Jianbo Shu, Guangping Liu
BACKGROUND: Sublingual immunotherapy (SLIT) is effective and convenient for many allergic patients but it is still ineffective for many children with allergic rhinitis (AR). In previous studies, most of the patients with poor efficacy of SLIT used the method of individualized adjustment of drug dosage. Currently, there are few reports on the relationship between serum vitamin D3 level and the efficacy of SLIT. METHODS: In this study, 153 patients with AR who received SLIT were selected as the study objects...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910104/lessons-learned-by-thoracic-surgeons-during-the-covid-19-pandemic
#19
JOURNAL ARTICLE
Helen J Madsen, Anne Lambert-Kerzner, Ellison Mucharsky, Joseph D Phillips, Elizabeth A David, David D Odell, Adam R Dyas, Robert A Meguid
BACKGROUND: The scale of the coronavirus disease 2019 (COVID-19) pandemic has necessitated healthcare systems to adapt and evolve, altering physician roles and expectations. Thoracic surgeons have seen practice changes from new COVID-19 consults to necessary delay and triage of elective care. The goal of this study was to understand the impact of COVID-19 on thoracic surgeon experiences in order to anticipate roles and changes in practice in future such circumstances. METHODS: Semi-structured, qualitative individual telephone interviews were conducted with thoracic surgeons...
February 28, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36910103/intrathoracic-vacuum-therapy-for-the-therapy-of-pleural-empyema-a-systematic-review-and-analysis-of-the-literature
#20
REVIEW
Björn-Ole Stüben, Gabriel A Plitzko, Matthias Reeh, Nathaniel Melling, Jakob R Izbicki, Kai Bachmann, Michael Tachezy
BACKGROUND: Pleural empyema is a serious and potentially deadly disease leading to a significant burden on health care systems. Conservative and surgical treatment results remain poor, with high morbidity and mortality rates. Patients with pleural empyema are often multimorbid and poor candidates for surgery. Therefore, it appears sensible to explore alternative, less invasive treatment options. Recently, the well-established vacuum sponge therapy has been adopted in the treatment of pleural infections...
February 28, 2023: Journal of Thoracic Disease
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