Zuhir Bodalal, Nino Bogveradze, Leon C Ter Beek, Jose G van den Berg, Joyce Sanders, Ingrid Hofland, Stefano Trebeschi, Kevin B W Groot Lipman, Koen Storck, Eun Kyoung Hong, Natalya Lebedyeva, Monique Maas, Regina G H Beets-Tan, Fernando M Gomez, Ieva Kurilova
BACKGROUND: Tumour hypoxia is a negative predictive and prognostic biomarker in colorectal cancer typically assessed by invasive sampling methods, which suffer from many shortcomings. This retrospective proof-of-principle study explores the potential of MRI-derived imaging markers in predicting tumour hypoxia non-invasively in patients with colorectal liver metastases (CLM). METHODS: A single-centre cohort of 146 CLMs from 112 patients were segmented on preoperative T2-weighted (T2W) images and diffusion-weighted imaging (DWI)...
July 21, 2023: Insights Into Imaging