journal
Journals Therapeutic Advances in Chroni...

Therapeutic Advances in Chronic Disease

https://read.qxmd.com/read/37928629/pyoderma-gangrenosum-in-ulcerative-colitis-patient-treated-with-vedolizumab-adsorptive-granulocyte-monocyte-apheresis-as-a-new-therapeutic-option-refractory-cases-a-case-report-and-literature-review
#21
Mauro Mastronardi, Elisabetta Cavalcanti, Nunzia Labarile, Raffaele Armentano, Francesco Gabriele, Margherita Curlo
Extraintestinal manifestations occur rather frequently in ulcerative colitis (UC) and Crohn's disease patients and are usually related to an exacerbation of the underlying intestinal bowel disease but sometimes may run a course independent of the inflammatory bowel diseases (IBD). About one-third of patients with IBD develop extraintestinal manifestations, such as pyoderma gangrenosum (PG). PG is an uncommon inflammatory skin disorder of unknown pathogenesis. There are no specific serological or histological markers, and diagnosis is predominantly clinical...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37928628/spleen-stiffness-determined-by-spleen-dedicated-device-accurately-predicted-esophageal-varices-in-cirrhosis-patients
#22
JOURNAL ARTICLE
Jiqing Liu, Hangfei Xu, Weiyuan Liu, Hongmei Zu, Huiguo Ding, Fankun Meng, Jing Zhang
BACKGROUND: The advantages of spleen stiffness in prediction of high-risk varices (HRV) in cirrhosis patients have been confirmed. Recently, a new device utilizing a 100 Hz probe dedicated to spleen stiffness measurement (SSM) was developed. OBJECTIVES: To validate the clinical applicability of SSM@100 Hz in predicting HRV by comparing it with other non-invasive tests (NITs). DESIGN: A prospective cohort study. METHODS: A total of 171 cirrhosis patients who underwent esophagogastroduodenoscopy (EGD) examination were included in this study...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37901688/comparative-short-term-risks-of-infection-and-serious-infection-in-patients-receiving-biologic-and-small-molecule-therapies-for-psoriasis-and-psoriatic-arthritis-a-systemic-review-and-network-meta-analysis-of-randomized-controlled-trials
#23
JOURNAL ARTICLE
Hsien-Yi Chiu, Yi-Teng Hung, Yu-Huei Huang
BACKGROUND: Infection events are a major concern for patients and physicians when making psoriasis treatment decisions. OBJECTIVE: To estimate the relative short-term risks of infection and serious infection for biologic and small molecule therapies in the treatment of moderate-to-severe plaque psoriasis (PsO) and psoriatic arthritis (PsA). DATA SOURCES AND METHODS: A systematic literature search of the PubMed, EMBASE, and Web of Science databases was conducted on 17 June 2022...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37854457/a-new-dual-function-dorsal-root-ganglion-stimulation-in-pain-management-a-technical-note-and-case-report
#24
Qiao Wang, Rui Han, Rong Hu, Qianxi Liu, Dong Huang, Haocheng Zhou
Sensitization of dorsal horn ganglion sensory neuron plays a crucial role in the maintenance of chronic pain disorder. Multiple interventions targeting dorsal horn ganglion can provide considerable relief of pain, including selective nerve root block, pulsed radiofrequency, and electrical nerve stimulation technique. It remains controversial about the superiority of neuromodulation mentioned above due to distinct pattern of analgesic mechanism. Here, we reported one 71-year-old male presenting at our pain clinic with severe, unilateral lower limb pain caused by postherpetic neuralgia...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37841213/complementary-and-alternative-medicine-for-long-covid-a-systematic-review-of-randomized-controlled-trials
#25
REVIEW
Juan Yang, Kia Hui Lim, Kia Teng Lim, Jeffrey T Woods, Arya B Mohabbat, Dietlind L Wahner-Roedler, Ravindra Ganesh, Brent A Bauer
BACKGROUND: Complementary and alternative medicine (CAM) interventions are growing in popularity as possible treatments for long COVID symptoms. However, comprehensive analysis of current evidence in this setting is still lacking. OBJECTIVE: This study aims to review existing published studies on the use of CAM interventions for patients experiencing long COVID through a systematic review. DESIGN: Systematic review of randomized controlled trials (RCTs)...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37841212/comparison-of-the-profiles-of-first-line-pd-1-pd-l1-inhibitors-for-advanced-nsclc-lacking-driver-gene-mutations-a-systematic-review-and-bayesian-network-meta-analysis
#26
JOURNAL ARTICLE
Fu Wenfan, Xu Manman, Shi Xingyuan, Jiang Zeyong, Zhao Jian, Dai Lu
BACKGROUND: Numerous first-line immune checkpoint inhibitors (ICI) were developed for patients with advanced non-small cell lung cancer (NSCLC) lacking driver gene mutations. However, this group consists of a heterogeneous patient population, for whom the optimal therapeutic choice is yet to be confirmed. OBJECTIVE: To identify the best first-line immunotherapy regimen for overall advanced NSCLC patients and different subgroups. DESIGN: Systematic review and Bayesian network meta-analysis (NMA)...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37822769/medication-adherence-in-medicare-enrolled-older-adults-with-asthma-and-chronic-obstructive-pulmonary-disease-before-and-during-covid-19-pandemic
#27
JOURNAL ARTICLE
Ligang Liu, Armando Silva Almodóvar, Milap C Nahata
BACKGROUND: Medication adherence in Medicare-enrolled older adults with asthma and chronic obstructive pulmonary disease (COPD) before and during the coronavirus disease 2019 (COVID-19) pandemic is unknown. OBJECTIVES: To evaluate medication adherence and determinants of high adherence before and during the COVID-19 pandemic in this population. DESIGN: Retrospective cohort study. METHODS: The proportion of days covered (PDC) reflected medication adherence from January to July 2019 and from January to July 2020...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37790945/a-narrative-review-of-neuro-ophthalmologic-disease-in-african-americans-and-hispanics-with-multiple-sclerosis
#28
REVIEW
Lauren Tardo, Amber Salter, Melanie Truong-Le, Lindsay Horton, Kyle M Blackburn, Peter V Sguigna
Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, with vision loss in the disease representing the second largest contributor to disability. In particular, African-American patients with MS are noted to have lower vision than their Caucasian counterparts. In this review, we examine the disparities in eye diseases in the MS population with our gaps in knowledge and discuss the underlying nature of pathological disparities.
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37745816/relationship-between-vascular-access-and-angulation-of-vena-cava-filter-at-placement-and-retrieval-a-multicenter-retrospective-cohort-study
#29
JOURNAL ARTICLE
Maofeng Gong, Rui Jiang, Boxiang Zhao, Jie Kong, Zhengli Liu, Cheng Qian, Xu He, Jianping Gu
BACKGROUND: Inferior vena cava (IVC) filters are commonly used intravascular devices designed to prevent fatal pulmonary embolism (PE), maintaining the IVC filter as centered as possible is fundamental for achieving its filtration function. OBJECTIVE: This study aimed to characterize the tilt angles of IVC filter between the vascular access of internal jugular vein (IJV) and femoral vein (FV), as well as to identify factors associated with increased or decreased tilt angles between placement and retrieval...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37720595/corrigendum-to-air-pollution-and-mortality-in-patients-with-chronic-obstructive-pulmonary-disease-a-cohort-study-in-south-korea
#30
(no author information available yet)
[This corrects the article DOI: 10.1177/20406223231176175.].
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37720594/third-line-treatment-patterns-and-clinical-outcomes-for-metastatic-colorectal-cancer-a-retrospective-real-world-study
#31
JOURNAL ARTICLE
Ting Deng, Jingjing Duan, Ming Bai, Le Zhang, Hongli Li, Rui Liu, Tao Ning, Shaohua Ge, Xia Wang, Yuchong Yang, Zhi Ji, Feixue Wang, Yi Ba
BACKGROUND: There are multiple recommendations on the third-line therapy of metastatic colorectal cancer (mCRC); however, no consensus has been reached. OBJECTIVES: This study aimed to explore the patient demographics and the real-world third-line treatment landscape of mCRC. DESIGN: A retrospective real-world cohort study. METHODS: Electronic medical records of mCRC patients from Tianjin Medical University Cancer Institute and Hospital between 2013 and 2020 were collected...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37720593/impact-of-local-drug-delivery-and-natural-agents-as-new-target-strategies-against-periodontitis-new-challenges-for-personalized-therapeutic-approach
#32
REVIEW
Gaia Viglianisi, Simona Santonocito, Saturnino Marco Lupi, Mariacristina Amato, Gianrico Spagnuolo, Paolo Pesce, Gaetano Isola
Periodontitis is a persistent inflammation of the soft tissue around the teeth that affects 60% of the population in the globe. The self-maintenance of the inflammatory process can cause periodontal damage from the alveolar bone resorption to tooth loss in order to contrast the effects of periodontitis, the main therapy used is scaling and root planing (SRP). At the same time, studying the physiopathology of periodontitis has shown the possibility of using a local drug delivery system as an adjunctive therapy...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37720592/effect-of-postoperative-radiotherapy-on-survival-in-patients-with-completely-resected-and-pathologically-confirmed-stage-n2-non-small-cell-lung-cancer-a-systematic-review-and-meta-analysis
#33
JOURNAL ARTICLE
Lin Wang, Wenyu Chen, Xiaofei Xu, Wenbo Chen, Derong Bao, Ye Zhang, Yufen Xu
BACKGROUND: The role of postoperative radiotherapy (PORT) for patients with completely resected stage N2 non-small-cell lung cancer (NSCLC) has been controversial. This study aimed to investigate the efficacy of PORT and prognosis in these patients. OBJECTIVES: An updated meta-analysis was conducted in this study to investigate the efficacy of PORT and prognosis in patients with completely resected and pathologically confirmed stage N2 NSCLC. DESIGN: This study is a systematic review and meta-analysis...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37664176/high-normal-free-thyroxine-level-is-related-with-decreased-bone-mineral-density-in-nonobese-male-patients-with-type-2-diabetes-over-50%C3%A2-years-old
#34
JOURNAL ARTICLE
Hanxin Zhao, Dike Shi, Guoxing Wang, Yu Ruan, Xiaocheng Feng, ChengFang Jia, Qingqing Wang, Xuehong Dong
BACKGROUND: The prevalence of 'low bone mineral density (BMD)' in Type 2 diabetes (T2DM), especially stratified by body mass index, is seldom reported. The relation of the euthyroid range and low BMD in T2DM remains to be further elucidated. OBJECTIVES: We aim to investigate the thyroid hormones' impact on BMD among euthyroid patients with T2DM. DESIGN AND METHODS: A total of 1452 hospitalized T2DM patients with normal thyroid function (43...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37655266/recalcitrant-nodular-scabies-showing-excellent-response-to-tofacitinib-five-case-reports
#35
Yu-Kun Zhao, Jing-Fa Lu, Juan-Hua Liu, Hui-Hui Wu, Lu-Li Song, Chun-Lei Wan, Di-Qing Luo
Scabies is a contagious skin condition caused by Sarcoptes scabiei , and it is always associated with an intense, unbearable, nocturnal deteriorating itch. Its presentations include classic burrows, erythema, pruritic papules, pustules, vesicles, and inflammatory nodules, with diffuse or localized distribution on the finger webs, wrist flexors, elbows, axillae, buttocks, genitalia, and breasts. Nodular scabies is an uncommon clinical variant of scabies. Its management is still challenging for some patients up to date, although topical, intralesional or systemic corticosteroids, topical calcineurin inhibitors, and crotamiton as well as cryotherapy alone or in different combinations are used...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37637372/distinguishing-bronchoscopically-observed-anatomical-positions-of-airway-under-by-convolutional-neural-network
#36
JOURNAL ARTICLE
Chongxiang Chen, Felix Jf Herth, Yingnan Zuo, Hongjia Li, Xinyuan Liang, Yaqing Chen, Jiangtao Ren, Wenhua Jian, Changhao Zhong, Shiyue Li
BACKGROUND: Artificial intelligence (AI) technology has been used for finding lesions via gastrointestinal endoscopy. However, there were few AI-associated studies that discuss bronchoscopy. OBJECTIVES: To use convolutional neural network (CNN) to recognize the observed anatomical positions of the airway under bronchoscopy. DESIGN: We designed the study by comparing the imaging data of patients undergoing bronchoscopy from March 2022 to October 2022 by using EfficientNet (one of the CNNs) and U-Net...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37601039/association-between-serum-trace-elements-and-sleep-disturbance-in-patients-with-decompensated-cirrhosis
#37
JOURNAL ARTICLE
Ziyue Zhang, Yangyang Hui, Wanting Yang, Gaoyue Guo, Binxin Cui, Chaoqun Li, Xiaoyu Wang, Xiaofei Fan, Chao Sun
BACKGROUND: Sleep disturbance and trace elements imbalance are common features in patients with decompensated cirrhosis, partially sharing similar mechanistic contributors and linking to adverse outcomes. However, there is a paucity of data concerning their relationship. OBJECTIVES: To investigate the association between serum trace elements levels and sleep quality in the context of cirrhosis. DESIGN: Cross-sectional study. METHODS: We consecutively enrolled 160 patients with decompensated cirrhosis...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37601038/two-year-real-world-outcome-data-from-a-single-tertiary-centre-shows-reduced-ustekinumab-persistence-in-a-non-bio-na%C3%A3-ve-crohn-s-disease-cohort-with-penetrating-disease-ostomies-and-sarcopenia
#38
JOURNAL ARTICLE
Saskia Inniss, Konstantinos C Fragkos, Lisa Whitley, Rachel Wimpory, Eleanor Rebello, Ana Lisboa, Tanvi Khetan, Jasmine Hassan, Kate Simpson, Anisha Bhagwanani, Roser Vega, Ioanna Parisi, Paul Harrow, Edward Seward, Sara McCartney, Stuart Bloom, Andrew M Smith, Andrew Plumb, Farooq Z Rahman
BACKGROUND: Ustekinumab was approved in 2016 for the treatment of moderate-severe Crohn's disease (CD). Clinical trials and real-world studies have suggested ustekinumab to be a safe and effective treatment; however, studies to date infrequently use imaging techniques to predict response to biologics in CD. OBJECTIVES: We assessed the 2-year real-world effectiveness and safety of ustekinumab in a tertiary CD cohort with the use of novel imaging techniques. DESIGN: Retrospective cohort study...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37577106/the-use-of-complementary-and-alternative-medicine-for-the-treatment-of-gastrointestinal-symptoms-in-long-covid-a-systematic-review
#39
REVIEW
Brent Gawey, Juan Yang, Brent Bauer, Joanne Song, Xiao Jing Wang
BACKGROUND: Most people with coronavirus disease 2019 (COVID-19) experience resolution of symptoms within days to weeks following initial infection. In a subset of individuals, symptoms persist longer than 4 weeks, known as 'Long COVID'. Many gastrointestinal (GI) symptoms persist as part of this syndrome; yet, an approach to treatment remains unclear. Prior studies have demonstrated the efficacy of complementary and alternative medicine (CAM) for the treatment of acute COVID-19 infections, but little data exist regarding the potential use of CAM in the treatment of Long COVID...
2023: Therapeutic Advances in Chronic Disease
https://read.qxmd.com/read/37546700/hair-repigmentation-and-regrowth-in-a-dupilumab-treated-paediatric-patient-with-alopecia-areata-and-atopic-dermatitis-a-case-report
#40
Xin Yan, Munire Tayier, Sin Tong Cheang, Zhongmin Liao, Yi Dong, Yifeng Yang, Yanting Ye, Xingqi Zhang
Alopecia areata (AA) is a chronic inflammatory disease mainly involving Th1 immunoreaction, but Th2 is also involved. A 9-year-old girl presented to our clinic with severe alopecia for 2 months and pruritus-related rashes for 8 years. She was diagnosed with AA and atopic dermatitis (AD), and the Severity of Alopecia Tool (SALT) score was 98. She used a 0.05% halometasone cream (occlusive dressing) topically applied overnight (6 days weekly) for 10 months. After 2 months of treatment, she had regrowth of both black and white hair...
2023: Therapeutic Advances in Chronic Disease
journal
journal
43051
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.