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Case Reports in Ophthalmology

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https://read.qxmd.com/read/30687074/acute-onset-optic-neuropathy-in-wilson-s-disease
#1
Liyung Tiffany Chou, Derek Horkey, Mark Slabaugh
Wilson's disease (WD), also known as hepatolenticular degeneration, is a rare autosomal recessive condition of excess copper accumulation that is most commonly associated with hepatic, neurologic, psychiatric, and ocular manifestations. While Kayser-Fleischer rings and sunflower cataracts are well known in WD, visual impairment is very rare. We report the case of a 20-year-old female who presented with acute liver failure and associated monocular vision loss. WD was found to be a cause of her liver disease and decreased vision...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30687073/diffuse-large-b-cell-lymphoma-of-the-lacrimal-sac-in-a-japanese-patient
#2
Satoshi Kakutani, Yasuhiro Takahashi, Ma Regina Paula Valencia, Hirohiko Kakizaki
Purpose: To report a Japanese patient with diffuse large B-cell lymphoma (DLBCL) in the lacrimal sac. Methods: This is a case report of a 52-year-old Japanese woman who presented with a 3-month history of epiphora on the right side and a 1-month history of swelling on the right medial canthal area. Lacrimal sac irrigation showed patency of the lacrimal drainage system. Imaging studies revealed a lacrimal sac mass with involvement of the nasolacrimal duct. Results: Histopathology and immunohistochemistry of the biopsy specimen revealed DLBCL...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30687072/a-5-year-old-case-of-choroidal-neovascularization-in-enhanced-s-cone-syndrome-treated-with-ranibizumab
#3
Federica Bertoli, Silvia Pignatto, Francesca Rizzetto, Paolo Lanzetta
Introduction: We describe the youngest case of enhanced S-cone syndrome (ESCS) associated with choroidal neovascularization (CNV) successfully treated with intravitreal ranibizumab injections. Case Report: A 5-year-old boy presented with round-shaped fibrotic subretinal lesions in both eyes with surrounding subretinal fluid and progressive visual deterioration in the right eye. Fine foci of increased autofluorescence were observed along the arcades in both eyes...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30687071/exudative-type-3-retinal-arteriovenous-malformation-in-a-pediatric-patient
#4
Helena Dens, Ingele Casteels
We describe a 7-year-old girl who developed exudation nasally to the right optic disc due to retinal arteriovenous malformation. Fluorescein angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography were performed. We give an overview of the different imaging techniques and discuss the differential diagnosis. Since there was no visual impairment, no treatment was started. A spontaneous decrease in edema and exudation was noted after 6 months.
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30687070/successful-certolizumab-pegol-treatment-of-chronic-anterior-uveitis-associated-with-psoriasis-vulgaris
#5
Keiko Yamaguchi, Takaaki Hayashi, Genichiro Takahashi, Mami Momose, Akihiko Asahina, Tadashi Nakano
This report presents details on a 45-year-old male Japanese patient with chronic and refractory anterior uveitis associated with psoriasis vulgaris who was administered certolizumab pegol (CZP), which is an anti-tumor necrosis factor alpha (TNF-α) monoclonal antibody. Although CZP has only been formally approved for rheumatoid arthritis treatment in Japan, a clinical trial allowed us to assess CZP effectiveness in this patient. The grade 3+ anterior chamber inflammation (for both the cells and flare) observed at baseline improved to grade 0 at 3 months post-treatment...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30687069/ocular-complications-from-retained-intraocular-ointment-discovered-33-months-after-cataract-surgery
#6
Riley N Sanders, David B Warner, Lindsey R Adams, Ahmed A Sallam, Sami H Uwaydat
Topical antibiotic and steroid ointments are sometimes used topically at the conclusion of intraocular surgery, and inadvertent entry into the eye has been reported. Dispersed ointment droplets or consolidated globules in the anterior chamber (AC) can sometimes be visualized on exam. Occasionally, intraocular ointment is found incidentally without apparent toxic effect, but retained ointment usually presents with early or delayed intraocular inflammation, pressure rise, macular edema, or corneal edema. The usual treatment for toxicity from retained ointment is removal of the ointment...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30631277/multimodal-imaging-in-a-case-of-idiopathic-neuroretinitis
#7
Yuya Esaki, Yoshio Hirano, Yusuke Yasuda, Taneto Tomiyasu, Norihiro Suzuki, Tsutomu Yasukawa, Yuichiro Ogura
A 37-year-old woman presented with painful visual loss in the left eye for 2 weeks. The best-corrected visual acuity was 20/200. Ophthalmic examination of the left eye revealed vitreous cells, optic disc swelling, serous retinal detachment, and macular star-figure hard exudates. Swept-source optical coherence tomography showed both inner and outer retinas were swollen, the choroid was thickened, and the corresponding retinal pigment epithelium was elevated. Wide-field indocyanine green angiography disclosed multiple hypofluorescent spots in the mid-periphery...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30631276/postoperative-late-onset-endophthalmitis-caused-by-leishmania-donovani-a-case-report
#8
Bojan Kozomara, Ernesta Potkonjak, Ratimir Lazic, Sanja Savicic, Nikica Gabric
Leishmania donovani is a human blood parasite that belongs to the genus Leishmania . We would like to present a case of late Leishmania donovani endophthalmitis in one eye of a patient that underwent simultaneous bilateral grade 3 cataract surgery.
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30631275/corneal-toxicity-induced-by-abt-414-therapy-for-glioblastoma-multiforme-a-case-report
#9
Hamoon Eshraghi, Dimosthenis Mantopoulos, Leejee H Suh, Francisco Zaldana, Howard F Fine
Background: To describe a case of corneal toxicity associated with the use of the epidermal growth factor receptor (EGFR) inhibitor ABT-414 in the treatment of glioblastoma multiforme. Case Presentation: Case report of a 56-year-old male with glioblastoma multiforme who developed mild painless blurred vision after systemic treatment with the investigational EGFR inhibitor ABT-414. The patient had best corrected visual acuity of 20/60 right eye and 20/50 left eye...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30631274/microvascular-capillary-plexus-findings-of-commotio-retinae-on-optical-coherence-tomography-angiography
#10
Ahmad M Mansour, Carol L Shields
Optical coherence tomography (OCT) and histopathology features of commotio retinae (CR) have been established, but alterations of the microvascular macular capillary plexus on OCT angiography (OCTA) has not been previously studied. We present a 46-year-old man who sustained a tennis ball injury to the right eye with visual acuity reduction to 20/30 and grey-white deep macular discoloration, suggestive of CR. Spectral-domain OCT (SD-OCT) showed increased reflectivity and thickness of the ellipsoid zone (junction of photoreceptor inner and outer segments)...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30519183/off-label-use-of-phakic-intraocular-lens-with-a-piggyback-technique
#11
Tadgh Schempf, Hoon C Jung
Purpose: We report a case of a highly myopic pseudophakic patient who received off-label placement of a phakic intraocular lens (pIOL) via a "piggyback" technique, allowing the placement of an intraocular lens (IOL) in his fellow eye, resulting in improved visual acuity and emmetropia. Case Report: A 66-year-old, highly myopic, pseudophakic male with an IOL implant in his left eye was referred for second opinion for surgical options for his phakic right eye...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30519182/diagnosis-clinical-trend-and-treatment-of-diffuse-lamellar-keratitis-after-femtosecond-laser-assisted-in-situ-keratomileusis-a-case-report
#12
Angelo Balestrazzi, Alessandra Balestrazzi, Maria Ilaria Giannico, Paolo Michieletto, Emilio Balestrazzi
We report a severe case of diffuse lamellar keratitis (DLK) following femtosecond laser-assisted in situ keratomileusis (femto-LASIK). A 25-year-old man was submitted to 150 kHz iFS® IntraLase-assisted LASIK in both eyes for compound myopic astigmatism. The day after surgery, clinical examination showed a diffuse whitish granular cell reaction particularly in the right eye. High-dose dexamethasone eyedrops with topical antibiotic and artificial tears were prescribed. Five days after surgery, a central corneal opacity with convergent striae was detected at biomicroscopy...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30483110/iris-morphological-features-in-patients-with-360%C3%A2-angle-closure-neovascular-glaucoma-an-anterior-segment-optical-coherence-tomography-study
#13
Yui Kobayashi, Shunsuke Nakakura, Etsuko Terao, Yuki Fujio, Kanae Matsuya, Hitoshi Tabuchi, Yasuhiro Takahashi, Yoshiaki Kiuchi
Purpose: To investigate iris morphological features in 360° angle-closure neovascular glaucoma (NVG) by swept-source anterior segment optical coherence tomography (ASOCT). Patients and Methods: In this retrospective, clinic-based, comparative study, 14 patients with 360° angle-closure NVG and 14 healthy age-matched control subjects were enrolled. All patients enrolled had no prior glaucoma surgery but underwent cataract surgery with intraocular lens implantation...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30483109/bilateral-spontaneous-hyphemas-in-a-patient-with-aplastic-anemia
#14
Mohammad Z Siddiqui, Grant Gebhard, Alice Behrens, Ahmed Sallam, Sami Uwaydat
Bilateral spontaneous hyphemas are a rare ophthalmic event. Aplastic anemia is a hematologic condition with well-documented manifestations in the posterior segment but not the anterior segment. We present a patient with aplastic anemia without obvious risk factors for hyphema who developed bilateral spontaneous hyphemas. To our knowledge, this is the first reported case of bilateral spontaneous hyphemas in a patient with aplastic anemia.
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30483108/detection-of-candida-endophthalmitis-in-a-newborn-using-handheld-spectral-domain-optical-coherence-tomography
#15
Carlos M Dulanto-Reinoso, Maria Ana Martinez-Castellanos
In a newborn with candidemia, two retinal lesions were seen without external inflammatory signs or reaction in the anterior chamber or vitreous. However, handheld spectral domain-optical coherence tomography (HH SD-OCT) images show that one of the retinal lesions had a "firework display" projecting to the vitreous that was not identified in indirect ophthalmoscopy. This finding suggested a Candida endophthalmitis. HH SD-OCT findings allowed us to make an accurate diagnosis and, therefore, modified the decision-making process in the treatment of the pathology...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30483107/development-of-a-donor-tissue-holding-technique-for-descemet-s-membrane-endothelial-keratoplasty-using-a-25-gauge-graft-manipulator
#16
Akira Kobayashi, Hideaki Yokogawa, Natsuko Mori, Toshinori Masaki, Kazuhisa Sugiyama
Purpose: To report a modified surgical technique called the "donor tissue holding technique for Descemet's membrane endothelial keratoplasty (DMEK)" using a newly developed 25-gauge graft manipulator. Methods: Six consecutive patients exhibiting endothelial dysfunction were enrolled and treated by DMEK. In brief, after insertion of a DMEK donor into the anterior chamber, the edge of the roll was grasped using a graft manipulator and this grasp was maintained throughout the centering and opening of the roll (holding technique)...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30386228/lipemia-retinalis-macular-edema-and-vision-loss-in-a-diabetic-patient-with-a-history-of-type-iv-hypertriglyceridemia-and-pancreatitis
#17
John W Hinkle, Nidhi Relhan, Harry W Flynn
Background: Lipemia retinalis is a rare but known complication of elevated serum triglycerides. This case describes the clinical course of a diabetic patient who presented with lipemia retinalis and macular edema, which responded to systemic and local treatments. Case Report: A 40-year-old female with a history of type II diabetes mellitus, hypertriglyceridemia, and pancreatitis presented with decreased vision in the left eye. She had peripapillary and macular edema, intraretinal hemorrhages, and prominent exudates in the setting of lipemia retinalis due to type IV hypertriglyceridemia...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30323760/corneal-blood-staining-after-complicated-cataract-surgery
#18
Mark Krauthammer, Jorje Mandelblum, Oriel Spierer
Purpose: To report the case of a patient with corneal blood staining after a complicated cataract surgery. Observations: We report on a 68-year-old woman who developed corneal blood staining secondary to hyphema after cataract surgery, despite the fact that intraocular pressure was not increased for a prolonged time. The corneal staining spontaneously cleared from the periphery towards the center. It was fully resolved after 2.5 years of follow-up. Conclusions and Importance: In case of hyphema induced by cataract surgery, performance of early anterior chamber washout should be considered to prevent corneal blood staining and poor visual outcome...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30323759/development-of-central-serous-chorioretinopathy-following-chalazion-removal-with-intralesional-triamcinolone-injection-a-case-report
#19
Luca Rosignoli, Stephen Myles Potter, Andres Gonzalez, Sarina Amin, Syed G Khurshid
We report a case of central serous chorioretinopathy (CSC) that developed 1 month after an intralesional injection of triamcinolone acetonide that was administered during removal of a chalazion. The subretinal fluid and ipsilateral visual acuity (VA) worsened with initial observation. The edema resolved with verteporfin photodynamic therapy (PDT) 1 month after diagnosis, but VA did not improve during short-term follow-up. We conclude that CSC can occur as a complication of low-dose intrapalpebral corticosteroid administration and provide another example of the therapeutic role of PDT in the management of this disease...
September 2018: Case Reports in Ophthalmology
https://read.qxmd.com/read/30283328/blood-in-a-haab-stria
#20
Vânia Lages, João Coelho, Carolina Abreu, Maria João Menéres, Irene Barbosa
We describe a case of an asymptomatic and spontaneous intracorneal hemorrhage in an adult with congenital glaucoma and blood collected in a Haab stria.
May 2018: Case Reports in Ophthalmology
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