Carlo Trompetto, Lucio Marinelli, Laura Mori, Nicola Bragazzi, Giulia Maggi, Filippo Cotellessa, Luca Puce, Lucilla Vestito, Franco Molteni, Giulio Gasperini, Nico Farina, Luciano Bissolotti, Francesco Sciarrini, Marzia Millevolte, Fabrizio Balestrieri, Domenico Antonio Restivo, Carmelo Chisari, Andrea Santamato, Alessandra Del Felice, Paolo Manganotti, Carlo Serrati, Antonio Currà
By blocking the release of neurotransmitters, botulinum toxin A (BoNT-A) is an effective treatment for muscle over-activity and pain in stroke patients. BoNT-A has also been reported to increase passive range of motion (p-ROM), the decrease of which is mainly due to muscle shortening (i.e., muscle contracture). Although the mechanism of action of BoNT-A on p-ROM is far from understood, pain relief may be hypothesized to play a role. To test this hypothesis, a retrospective investigation of p-ROM and pain was conducted in post-stroke patients treated with BoNT-A for upper limb hypertonia...
May 13, 2023: Toxins