John D Lee, Jakob Richter, Martin R Pfaller, Jason M Szafron, Karthik Menon, Andrea Zanoni, Michael R Ma, Jeffrey A Feinstein, Jacqueline Kreutzer, Alison L Marsden, Daniele E Schiavazzi
The substantial computational cost of high-fidelity models in numerical hemodynamics has, so far, relegated their use mainly to offline treatment planning. New breakthroughs in data-driven architectures and optimization techniques for fast surrogate modeling provide an exciting opportunity to overcome these limitations, enabling the use of such technology for time-critical decisions. We discuss an application to the repair of multiple stenosis in peripheral pulmonary artery disease through either transcatheter pulmonary artery rehabilitation or surgery, where it is of interest to achieve desired pressures and flows at specific locations in the pulmonary artery tree, while minimizing the risk for the patient...
March 27, 2024: International Journal for Numerical Methods in Biomedical Engineering