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Journal of Neurogastroenterology and Motility

Beom Jin Kim, Braden Kuo
Gastroparesis and functional dyspepsia are 2 of the most common gastric neuromuscular disorders. These disorders are usually confused, having both similarities and differences. The pathophysiology of these disorders involves abnormal gastric motility, visceral hypersensitivity, mucosal inflammation, and various cellular changes. Both disorders have similar symptoms such as epigastric pain or discomfort, early satiety, and bloating. If patients suspected of having either gastroparesis or functional dyspepsia present with upper gastrointestinal symptoms, they should undergo upper endoscopy to exclude an alternative organic cause...
December 3, 2018: Journal of Neurogastroenterology and Motility
Rapat Pittayanon, Somchai Leelakusolvong, Ratha-Korn Vilaichone, Jarin Rojborwonwitaya, Sombat Treeprasertsuk, Pisaln Mairiang, Supphamat Chirnaksorn, Taned Chitapanarux, Uayporn Kaosombatwattana, Jaksin Sottisuporn, Inchaya Sansak, Pochamana Phisalprapa, Chalermrat Bunchorntavakul, Surapon Chuenrattanakul, Suriya Chakkaphak, Rattana Boonsirichan, Olarn Wiwattanachang, Monthira Maneerattanaporn, Wanich Piyanirun, Varocha Mahachai
The management of dyspepsia in limited-resource areas has not been established. In 2017, key opinion leaders throughout Thailand gathered to review and evaluate the current clinical evidence regarding dyspepsia and to develop consensus statements, rationales, levels of evidence, and grades of recommendation for dyspepsia management in daily clinical practice based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. This guideline is mainly focused on the following four topics: (1) evaluation of patients with dyspepsia, (2) management, (3) special issues (overlapping gastroesophageal reflux disease/irritable bowel syndrome and non-steroidal anti-inflammatory drug/aspirin use), and (4) long-term follow-up and management to provide guidance for physicians in Thailand and other limited-resource areas managing such patients...
November 23, 2018: Journal of Neurogastroenterology and Motility
Ju Yup Lee, Sung Kook Kim, Kwang Bum Cho, Kyung Sik Park, Joong Goo Kwon, Jin Tae Jung, Eun Young Kim, Byung Ik Jang, Si Hyung Lee
The original version of this article contains one mistake. The term "protein pump inhibitors (PPIs)" in the Introduction of page 219 should have been written as "proton pump inhibitors (PPIs)."
January 31, 2019: Journal of Neurogastroenterology and Motility
Oya Balcı Sezer, Taner Sezer
Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer."
January 31, 2019: Journal of Neurogastroenterology and Motility
Ram Dickman, Carla Maradey-Romero, Rachel Gingold-Belfer, Ronnie Fass
The original version of this article contains one mistake. The term "protein pump inhibitor" in the Abstract should have been written as "proton pump inhibitor."
January 31, 2019: Journal of Neurogastroenterology and Motility
Yong Sung Kim, Seong Hoon Park, Eul-Sig Choi, Suck Chei Choi
No abstract text is available yet for this article.
January 31, 2019: Journal of Neurogastroenterology and Motility
Bernhard Widmann, Christian Galata, Rene Warschkow, Ulrich Beutner, Önder Ögredici, Franc H Hetzer, Bruno M Schmied, Stefan Post, Lukas Marti
Background/Aims: The aim of this study was to evaluate the sustainability of sacral neuromodulation (SNM) success in patients with fecal incontinence (FI) and/or constipation. Methods: This is a retrospective analysis of a prospective database of patients who received SNM therapy for FI and/or constipation between 2006 and 2015. Success rates, complications and reintervention rates were assessed after up to 10 years of follow-up. Results: Electrodes for test stimulation were implanted in 101 patients, of whom 79 (78...
January 31, 2019: Journal of Neurogastroenterology and Motility
Shanbin Chen, Yangwenshan Ou, Liang Zhao, Yang Li, Zhenxing Qiao, Yanling Hao, Fazheng Ren
Background/Aims: Probiotics are expected to confer benefits on patients with constipation, but how probiotics act on constipated patients with variable stool consistencies remains unclear. We investigated the effect of Lactobacillus casei strain Shirota (LcS) on constipation-related symptoms, especially stool consistency, of constipated patients. Methods: Constipated patients meeting the Rome III criteria were divided into 3 groups according to the Bristol Stool Form Scale (BSFS): hard (hard stool [HS], BSFS < 3), normal (normal stool [NS], ≤ 3 BSFS ≤ 4), and soft (soft stool [SS], 4 < BSFS ≤ 5) stools...
January 31, 2019: Journal of Neurogastroenterology and Motility
Eun Mi Song, Jong Wook Kim, Sun-Ho Lee, Kiju Chang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Wook Jung, Byong Duk Ye, Jeong-Sik Byeon, Suk-Kyun Yang, Hyo Jeong Lee, Chang Sik Yu, Chan Wook Kim, Seong Ho Park, Jihun Kim, Seung-Jae Myung
Background/Aims: Previous studies from Korea have described chronic intestinal pseudo-obstruction (CIPO) patients with transition zone (TZ) in the colon. In this study, we evaluated the pathological characteristics and their association with long-term outcomes in Korean colonic pseudo-obstruction (CPO) patients with TZ. Methods: We enrolled 39 CPO patients who were refractory to medical treatment and underwent colectomy between November 1989 and April 2016 (median age at symptoms onset: 45 [interquartile range, 29-57] years, males 46...
January 31, 2019: Journal of Neurogastroenterology and Motility
Prashant Singh, Yoonjin Seo, Sarah Ballou, Andrew Ludwig, William Hirsch, Vikram Rangan, Johanna Iturrino, Anthony Lembo, Judy W Nee
Background/Aims: Although symptoms related to the pelvic floor, such as pelvic organ prolapse (POP) and lower urinary tract symptoms (LUTS), are common in patients with chronic constipation (CC), its impact is not clear. Our aims were to investigate the following (1) compare pelvic floor symptom related dysfunction in irritable bowel syndrome with constipation (IBS-C) and functional constipation (FC), and (2) symptom correlation with findings on anorectal manometry (ARM) and balloon expulsion test...
January 31, 2019: Journal of Neurogastroenterology and Motility
Marina Russo, Caterina Strisciuglio, Elena Scarpato, Dario Bruzzese, Marianna Casertano, Annamaria Staiano
Background/Aims: Functional constipation (FC) is aa frequent functional gastrointestinal disorder, diagnosed according to the Rome criteria. In this study, we compared Rome III and Rome IV criteria for the diagnosis of FC, and determined the prevalence of FC according to these criteria. Methods: Consecutive children between infancy and 17 years old were recruited for the study, excluding those with a known organic gastrointestinal disease. A prospective longitudinal design has beenused...
January 31, 2019: Journal of Neurogastroenterology and Motility
Giorgos Chouliaras, Christina Kondyli, Ilias Bouzios, Nick Spyropoulos, George P Chrousos, Eleftheria Roma-Giannikou
Background/Aims: The abdominal pain-related functional gastrointestinal disorders (AP-FGIDs) affect a significant proportion of the pediatric population and consist 1 of the most frequent causes for seeking medical advice. In this study, we aimed to assess the relation of dietary habits with the likelihood of AP-FGIDs. Methods: This was a school-based, cross-sectional study approved by the Greek Government authorities, after obtaining informed consent by the legal representatives of the children...
January 31, 2019: Journal of Neurogastroenterology and Motility
Jason R Baker, Joseph R Dickens, Mark Koenigsknecht, Ann Frances, Allen A Lee, Kerby A Shedden, James G Brasseur, Gordon L Amidon, Duxin Sun, William L Hasler
Background/Aims: High-resolution methods have advanced esophageal and anorectal manometry interpretation but are incompletely established for intestinal manometry. We characterized normal fasting duodeno-jejunal manometry parameters not measurable by standard techniques using clustered closely-spaced recordings. Methods: Ten fasting recordings were performed in 8 healthy controls using catheters with 3-4 gastrointestinal manometry clusters with 1-2 cm channel spacing...
January 31, 2019: Journal of Neurogastroenterology and Motility
Eun Jeong Gong, Kee Wook Jung, Yang-Won Min, Kyoung Sup Hong, Hye-Kyung Jung, Hee Jung Son, Do Yeon Kim, Jungbok Lee, Oh Young Lee
Background/Aims: The Gastroesophageal Reflux Disease Questionnaire (GerdQ) has been developed and validated as a tool for the diagnosis of gastroesophageal reflux disease (GERD) in patients with gastrointestinal symptoms. However, the GerdQ and the cutoff value for determining GERD has not been validated in Korea. Methods: Patients with symptoms suggestive of GERD were consecutively recruited. The Korean version of GerdQ was developed through a forward-backward translation process according to the cross-cultural adaptation method...
January 31, 2019: Journal of Neurogastroenterology and Motility
Su Youn Nam, Bum Joon Park, Yeong-Ah Cho, Kum Hei Ryu
Background/Aims: The effect of dietary micronutrients on non-erosive reflux disease (NERD) and reflux esophagitis is unclear. We aim to evaluate the gender-specific effect of micronutrient on erosive esophagitis and NERD. Methods: A total of 11 690 participants underwent endoscopy and completed 3-day recordings for dietary intake and questionnaires for reflux symptoms from 2004 to 2008. To evaluate the effect of dietary micronutrients on NERD or erosive esophagitis, adjusted regression analysis with odds ratio (OR) and 95% confidence interval (CI) was used...
January 31, 2019: Journal of Neurogastroenterology and Motility
Byeong Geun Song, Yang Won Min, Hyuk Lee, Byung-Hoon Min, Jun Haeng Lee, Poong-Lyul Rhee, Jae J Kim
Background/Aims: Esophagogastric junction outflow obstruction (EGJOO) is a diagnostically heterogeneous group with variable clinical relevance. We studied whether evaluation of bolus transit by multichannel intraluminal impedance (MII) is useful for discriminating clinically relevant EGJOO. Methods: A total 169 patients diagnosed as having EGJOO between June 2011 and February 2018 were analyzed. All the patients received a combined MII and high-resolution manometry (CMII-HRM)...
January 31, 2019: Journal of Neurogastroenterology and Motility
Mentore Ribolsi, Dario Biasutto, Antonio Giordano, Paola Balestrieri, Michele Cicala
Background/Aims: The role of esophageal motility in determining gastroesophageal reflux disease (GERD) severity has not been completely evaluated. A few studies have investigated high-resolution manometry (HRM) patterns during solid swallows. The present study evaluates the HRM patterns of non-erosive reflux disease (NERD) patients during both liquid and solid swallows and their correlation with the severity of GERD. Methods: In 23 NERD patients and 15 healthy volunteers (HVs) HRM was performed during a standard solid meal in a seated position, followed by 24-hour impedance-pH monitoring...
January 31, 2019: Journal of Neurogastroenterology and Motility
Dan Wang, Xiu Wang, Yao Yu, Xiaowen Xu, Jing Wang, Yuting Jia, Hong Xu
Background/Aims: The distribution and esophageal motor characteristics of Chinese patients with esophageal dysphagia who exhibit no structural abnormalities on esophagogastroduodenoscopy remain unclear. Our aim is to assess the esophageal motor patterns using high-resolution manometry (HRM) and classify them according to the Chicago classification version 3.0 (CC v3.0). Furthermore, we compared the CC v3.0 and the previous version 2.0 (CC v2.0) for diagnosis of motor disorders. Methods: Two hundred thirty-six (mean age 48...
January 31, 2019: Journal of Neurogastroenterology and Motility
Karol Kowalski, Agata Mulak
Disturbances along the brain-gut-microbiota axis may significantly contribute to the pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent cause of dementia characterized by a progressive decline in cognitive function associated with the formation of amyloid beta (Aβ) plaques and neurofibrillary tangles. Alterations in the gut microbiota composition induce increased permeability of the gut barrier and immune activation leading to systemic inflammation, which in turn may impair the blood-brain barrier and promote neuroinflammation, neural injury, and ultimately neurodegeneration...
January 31, 2019: Journal of Neurogastroenterology and Motility
Yoo Jin Lee, Kyung Sik Park
No abstract text is available yet for this article.
January 31, 2019: Journal of Neurogastroenterology and Motility
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