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Journals Journal of Population Therapeu...

Journal of Population Therapeutics and Clinical Pharmacology

https://read.qxmd.com/read/36398597/the-effect-of-favipiravir-on-liver-enzyme-among-patients-with-mild-to-moderate-covid-19-infection-a-prospective-cohort-study
#21
JOURNAL ARTICLE
Ahmed Hamza Al-Shammari, Mohammed Abd Ali Shahadha
Teratogenicity and hyperuricemia are considered as the major adverse effects of favipiravir, but less is known about other possible side effects which includes drug-induced liver damage and renal injury. In the current research, assessment of favipiravir-induced liver injury was performed by evaluating liver enzymes among patients with mild to moderate COVID-19 infection. A prospective cohort study was conducted on 66 patients diagnosed with mild to moderate COVID-19 infection who were treated with favipiravir for 5 days...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36371649/update-on-overview-of-pterygium-and-its-surgical-management
#22
REVIEW
Mitra Akbari
Pterygium is a bulbar conjunctival fibrovascular growth that crosses the limbus and extends onto the peripheral cornea, and in some cases leads to significant visual complications. The prevalence of this disease has been reported to be from 1.2% to about 40% in different parts of the world. Although there are various risk factors for pterygium, which include ultraviolet (UV) radiation, viral infection, hereditary factors, immune factors, aseptic inflammation, and environmental irritation, the pathogenesis of pterygium is mainly related to exposure to UV light...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36308280/predictors-of-sirolimus-pharmacokinetic-variability-identified-using-a-nonlinear-mixed-effects-approach-a-systematic-review
#23
REVIEW
Janthima Methaneethorn, Premsuda Art-Arsa, Ramanya Kosiyaporn, Nattawut Leelakanok
Several sirolimus (SRL) population pharmacokinetics (PopPK) were conducted to explain its pharmacokinetic variability, and the results varied across studies. Thus, we conducted a systematic review to summarize significant predictors influencing SRL pharmacokinetic variability. Moreover, discrepancies in model methodologies across studies were also reviewed and discussed. Four databases (PubMed, CINAHL Complete, Science Direct, and Scopus) were systematically searched. The PICO framework was used to identify eligible studies conducted in humans and employ a nonlinear-mixed effects strategy...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36214453/hyponatremia-timing-incidence-and-associated-risk-factors-in-patients-treated-with-cisplatin-for-lung-cancer-a-retrospective-study
#24
JOURNAL ARTICLE
Sumiaki Ogawa, Junya Sato, Rei Tanaka, Tatsuya Sakakibara, Michihiro Shino
The incidence of cisplatin-derived hyponatremia remains unknown, although nausea, vomiting, and renal dysfunction are common adverse events of cisplatin, a platinum-based preparation. The factor contributing to hyponatremia is described but not well known. This study aimed to retrospectively investigate the incidence of hyponatremia, timing, and associated risk factors. This study surveyed patients with lung cancer who received cisplatin chemotherapy from August 2013 to July 2019 at Shizuoka Cancer Center. The severity of hyponatremia was evaluated based on Common Terminology Criteria for Adverse Events...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196948/human-development-index-and-innovation-capabilities-in-the-health-sector-of-uae
#25
JOURNAL ARTICLE
Sultan Mohamed Al-Marzooqi, Ashraf M Zedan Al Dulaimi, Asmuliadi Lubis, Norrodzoh Binti Hj Siren, Sayyid Buhar Kassim
Based on human capital theory, the goal of this study was to look into the role of innovation capabilities in the UAE healthcare sector's competitiveness. Following the qualitative research design, data were gathered through interviews with 90 experts and professionals working in the health industry in UAE. Furthermore, the study also analyzed the UAE's Human Development Index (HDI), innovation capacities, and human development competitiveness from 2014 to 2020 using the conceptual statistics of Key Performance Indicators (KPIs) obtained in the health sector...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196947/long-covid-19-prevalence-among-a-sample-of-infected-people-in-erbil-city
#26
JOURNAL ARTICLE
Ahmed Sabah Hawar, Ali Shakir Dauod
BACKGROUND: Long-term effects of the disease were founded and described as post-COVID-19 syndrome post-COVID syndrome are the symptoms that develop and last for four weeks or even months and cannot be explained by an alternative diagnosis; symptoms may remain for >3 months. The cause of persistent symptoms is unclear. Objectives: This study aimed to Estimate the prevalence of residual symptoms among a sample of people infected with COVID-19 who survived and recovered in Erbil city and to find out the relation between the severity of the disease and post-COVID-19 syndrome...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196946/comparison-of-the-proposed-dcnn-model-with-standard-cnn-architectures-for-retinal-diseases-classification
#27
JOURNAL ARTICLE
Ramya Mohan, Kirupa Ganapathy, Rama Arunmozhi
Deep learning in medical image analysis has indicated increasing interest in the classification of signs of abnormalities. In this study, a new convolutional neural network (CNN) architecture (MIDNet18) Medical Image Detection Network was proposed for the classification of retinal diseases using optical coherence tomography (OCT) images. The model consists of 14 convolutional layers, seven Max Pooling layers, four dense layers, and one classification layer. A multi-class classification layer in the MIDNet18 is used to classify the OCT images into either normal or any of the three abnormal types: Choroidal Neovascularization (CNV), Drusen, and Diabetic Macular Edema (DME)...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196945/innovation-of-new-surgical-technique-to-contour-the-missing-bone-in-the-face-of-survivors-of-traffic-and-war-injuries-by-new-modified-problast-painted-with-a-mixture-of-biocompatible-materials
#28
JOURNAL ARTICLE
Sabah Hassan
The bone grafts taken from the patient himself (Auto genius graft) to restore the contour of the lost facial bone lost is the ideal technique on the road to recovery from injuries of war or traffic accidents. This novel surgical procedure utilizes a new modified Problast painted with a mixture of a biocompatible materials to restore the lost parts of the zygomatic bones, due to traffic accidents, shell injuries, or bullet injuries.
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196944/accuracy-of-office-hysteroscopy-in-diagnosis-of-endometrial-pathologies-compared-to-ultrasound-and-histopathology-in-baghdad-teaching-hospital
#29
JOURNAL ARTICLE
Farah Abdul Hussein Salih Al-Asadi, Shaymaa Kadhim Jasim
BACKGROUND: Menstrual problems with all manifestations ranging from life-threatening bleeding to amenorrhea are considered patterns of abnormal uterine bleeding (AUB), which is until now a popular reason for referral to the gynaecologic clinic and requires a special diagnostic tool. OBJECTIVE: To assess the accuracy of hysteroscopy in diagnosing endometrial pathologies and to compare it with sonographic and histopathologic reports. PATIENTS AND METHODS: A prospective study conducted in the Baghdad Teaching Hospital on 60 Iraqi females having varying complaints from abnormal uterine bleeding in pre- and post-menopausal women, infertility, and chronic pelvic pain with normal or abnormal ultrasound findings...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196943/formulation-development-and-evaluation-of-anti-inflammatory-and-antimicrobial-effects-of-a-novel-polyherbal-mouthwash-an-in-vitro-study
#30
JOURNAL ARTICLE
Bhavana Garapati, Jaiganesh Ramamurthy, Rajeshkumar Shanmugam
AIM: The aim of this study was to prepare a polyherbal mouthwash and evaluate its antimicrobial and anti-inflammatory efficacy against commercially available herbal mouthwash. The objective was to signify whether the novel herbal combination (extracts of Zingiber officinale [ginger], Curcuma longa [turmeric], and Syzygium aromaticum [clove] 5% v/w) could be a better alternative to commercially available herbal mouthwashes. MATERIALS AND METHODS: An in vitro study was undertaken in which extracts of Z...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196942/clinical-classification-of-torus-and-effectiveness-of-two-layer-bases-in-removable-dentures
#31
JOURNAL ARTICLE
Nurmukhamet Ruzuddinov, Saurbek Ruzuddinov, Igor Voronov, Kubeisin Altynbekov, Kalamkas Ruzuddinova
AIM: To study and systematize the complaints of patients with removable prostheses, paying attention to the clinical manifestation of the torus and its sensitivity, and to determine the effectiveness of the use of two-layer bases in removable prosthetics. METHODS: In the clinic of orthopedic dentistry, 104 people were examined and received orthopedic treatment, including 37 patients in the comparison group. The main number of patients up to 55.3, complained of poor fixation and violation of the chewing process...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196941/peculiarities-of-personality-adaption-to-psychological-traumas-in-neurotic-disorders
#32
JOURNAL ARTICLE
Dina R Timutsa, Vladimir D Mendelevich
BACKGROUND AND AIM: It is known that anticipatory processes play a leading role in the regulation of behavior. These processes act as a leading mechanism of the link in the mental regulation of behavior and activity. Violation of processes anticipates to a mismatch in the work of the adaption system, and, as a result, to maladaptive behavior. However, many issues related to the detection of anticipation disorders in various manifestations of diseases have been insufficiently studied. The features of individual prognosis depending on diseases are studied here...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196940/evaluation-of-dental-health-of-the-adult-population-of-kazakhstan-and-solutions-for-improving-removable-prosthetics
#33
JOURNAL ARTICLE
Nurmukhamet Ruzuddinov, Saurbek Ruzuddinov, Shayakhmetova Meiramkul Kozhakhmetovna, Turetay Ruzuddinov, Kamiyeva Naziya Amerbekkyzy
Screening studies on dental morbidity of elderly people in the urban and rural population of the Republic of Kazakhstan were conducted. Three age groups were investigated in the districts of Almaty and Almaty oblast: middle-aged (45-59 years old), elderly (60-79 years old) and the oldest (80 years and above). A high loss of teeth was revealed, which was 79.3% in the urban and 90.6% in the rural population of the Republic of Kazakhstan, respectively. Complete absence of teeth on the upper jaw was most common in rural and city dwellers in the oldest and elderly age groups...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196939/impact-of-the-coronavirus-pandemic-on-children-s-oral-health-and-caregiver-s-attitude-towards-teledentistry-a-kuwait-based-survey
#34
JOURNAL ARTICLE
Wasmiya A AlHayyan, Khalid Khalaf Alshamrani, Abdullah Mubarak Rasheed, Saed S H H Alenezi
OBJECTIVE: To evaluate the impact of the coronavirus pandemic on children's oral health and caregiver's attitude towards teledentistry. MATERIAL AND METHOD: A questionnaire was distributed to 583 caregivers of children aged between 3 and 10 years through electronic messages, which consisted of nine multiple choice questions divided into three parts. The first part included demographic data (age, gender, and educational level); the second part addressed the assessment of oral health of children by their caregivers during the lockdown, the reason and influence of the pandemic on the oral health of children; and the third part was related to caregiver's attitude towards healthcare system and teledentistry...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196938/modern-modified-aerosol-box-isolation-aid-for-oral-health-care-professionals-during-dental-procedures
#35
REVIEW
Hawazen A Radwan, Afnan I Alsaleem, Abdullah Alassaf, Basim Almulhim, Sara Ayid Alghamdi, Sreekanth Kumar Mallineni
COVID-19 affected healthcare professionals globally, especially dentists, which is airborne and transmitted through contact. Most dental procedures are aerosol generated and these aerosols in dental practice tend to transmit acute respiratory infections like COVID-19. Recently, a few authors recommended using the aerosol box to reduce the aerosol count in a dental setting. However, the study aims to describe and recommend a reformed aerosol box desand to practice safe dentistry.
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196937/prevalence-and-risk-factors-of-early-childhood-caries-in-the-middle-east-region-a-systematic-review
#36
REVIEW
Sunil Babu Kotha
OBJECTIVE: The purpose of this systematic review was to assess the prevalence and risk factors of early childhood caries (ECC) in the Middle East region in the age group 0-6 years. METHODS: A systematic literature search was performed in three major databases, Web of Science, PubMed, and Cochrane database, from January 1, 1960 to December 31, 2020, to identify the published literature on the prevalence and risk factors of ECC. All preschool children of 0-6 years of age irrespective of gender and socioeconomic status from the selected geographics were included...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196936/measurement-of-patient-satisfaction-with-two-different-restorative-materials-in-non-aesthetic-zone-area-by-using-ohip5-prospective-study
#37
JOURNAL ARTICLE
Riyadh A Alzunaydi, Rehan S Alsalem, Sami D Aldhuwayhi
BACKGROUND: Many dental restorative materials are used in dental clinics, while in a new practice, many countries are trying to ban dental amalgam for many reasons. Dental mercury is the main issue for suspending the use of dental amalgam. Another restoration method, the composite restoration for posterior and anterior teeth for esthetic porous, became the alternative to amalgam. AIM: To measure patient satisfaction with two different materials based on multiple criteria using an oral health impact profile (OHIP) form...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196935/sirt1720-promotes-survival-of-corneal-epithelial-cells-via-the-p53-pathway
#38
JOURNAL ARTICLE
Hayder AbdulHasan Jalil, Basma Talib Al-Sudani, Ghaith Ali Jasim
PURPOSE: To investigate the protective role of SRT1720 (SIRT1 activator) against the oxidative stress caused by H2 O2 in the corneal cell line. METHODS: Human corneal (2.040 pRSV-T) cell lines were cultured and treated with SRT1720 (as SIRT1 activator) and nicotinamide (NAM, a SIRT1 inhibitor), and incubated with H2 O2 . The expression level of SIRT1, p53, and acetyl-p53 was measured by western blot. Propidium iodine/annexin V-FITC staining, and flow cytometry was used to evaluate apoptosis...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196934/alpha-fetoprotein-and-high-sensitive-c-reactive-protein-levels-in-iraqi-patients-with-liver-cirrhosis
#39
JOURNAL ARTICLE
Wassan Abdul Kareem Abbas
BACKGROUND: Liver-related death globally is caused mainly by cirrhosis. It is the final grade of extensive liver fibrosis, in which the hepatic architecture is modified. Cirrhosis is a common disease worldwide and can be the end stage for several reasons such as obesity, non-alcoholic fatty liver, alcoholism, viral infection such as viral hepatitis, immune disorders, bile duct obstruction, and metabolic diseases. Alpha-fetoprotein (AFP) is defined as a protein secreted by the germinal yolk sac and liver...
2022: Journal of Population Therapeutics and Clinical Pharmacology
https://read.qxmd.com/read/36196933/pharmacology-teaching-in-dental-education-in-india-time-for-a-reappraisal
#40
JOURNAL ARTICLE
Md Faiz Akram, Seema Manak, Deep Inder, Md Asad Khan, Mohd Tariq Salman
India has a unique position with its vast population and rapidly increasing healthcare demand. Dental health is integral to a holistic health care need, and a robust dental education system is necessary. Dental education in India is mainly regulated by the Dental Councilof India, setting broad guidelines. Universities having dental colleges and institutes develop fine curriculum development and evaluation details. General and Dental Pharmacology and Therapeuticsis a crucial subject taught to undergraduate dental students during the second year of a 4-year duration course...
2022: Journal of Population Therapeutics and Clinical Pharmacology
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