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Journal of Nutrition and Metabolism

Laila Meija, Guna Havensone, Aivars Lejnieks
Increasing evidence shows that whole grain consumption is protective against metabolic disorders. Protective bioactive substances of whole grains include fibre and antioxidants. Activation of grains can increase the amount of phenolic compounds and their bioavailability, but there is little evidence about their effect on glycaemic and insulinemic responses. Therefore, the aim of this study was to investigate glycaemic and insulinemic responses after consumption of flakes made from activated wheat and activated triticale grains...
2019: Journal of Nutrition and Metabolism
Harry Freitag Luglio Muhammad, Dian Caturini Sulistyoningrum, Emy Huriyati, Yi Yi Lee, Wan Abdul Manan Wan Muda
Background: Coffee is suggested as an alternative option for weight loss but the relationship between coffee consumption and adiposity in population-based studies is still controversial. Therefore, this study was aimed at evaluating the relationship between coffee intake and adiposity in adults and to test whether uncoupling protein 2 (UCP2) gene variation was able to affect this relationship. Methods: This was a cross-sectional study conducted in male and female adults living in the urban area of Yogyakarta, Indonesia...
2019: Journal of Nutrition and Metabolism
Mohd Jokha Yahya, Patimah Binti Ismail, Norshariza Binti Nordin, Abdah Binti Md Akim, Wan Shaariah Binti Md Yusuf, Noor Lita Binti Adam, Nurul Fasihah Zulkifli
Type 2 diabetes mellitus (T2DM) is associated with a high incidence of nephropathy. The aim of this study was to investigate the association of a genetic polymorphism of carnosinase ( CNDP1-D18S880 and - rs2346061 ), endothelial nitric oxide synthase ( NOS3-rs1799983 ), and manganese superoxide dismutase ( MnSOD-rs4880 ) genes with the development of diabetic nephropathy among Malaysian type 2 diabetic patients. A case-control association study was performed using 652 T2DM patients comprising 227 Malays (without nephropathy = 96 and nephropathy = 131), 203 Chinese (without nephropathy = 95 and nephropathy = 108), and 222 Indians (without nephropathy = 136 and nephropathy = 86)...
2019: Journal of Nutrition and Metabolism
Benjamin M Savasky, David P Mascotti, Naren Patel, Edgardo Rodriguez-Collazo
Oxidative damage is the causal link to a multitude of pathologies, such as diabetes, arthritis, neuropathy, heart disease, and asthma. These conditions affect hundreds of millions of people nationwide, and billions worldwide. Even in otherwise healthy individuals, oxidative stress is a natural byproduct of metabolism that is augmented in "healthy" activities such as athletics. In many disease states, the pharmacological agents used to treat these conditions can induce oxidative damage and vitamin depletion...
2018: Journal of Nutrition and Metabolism
Luz Adriana Sarmiento-Rubiano, José Armando Angarita Ruidiaz, Héctor Fernando Suarez Dávila, Alfonso Suarez Rodríguez, Roberto C Rebolledo-Cobos, Jimmy E Becerra
Background: Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels. For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD), mainly those related with metabolic syndrome. Objective: To assess the relationship between the serum vitamin D (25-OH-D) levels and the metabolic syndrome markers in postmenopausal women. Methods: This descriptive and cross-sectional study was conducted in 183 postmenopausal women of four municipalities from Colombian Caribbean...
2018: Journal of Nutrition and Metabolism
Carolinne Thaísa de Oliveira Fernandes Miranda, Victor Hugo Rezende Duarte, Marina Sampaio de Menezes Cruz, Mychelle Kytchia Rodrigues Nunes Duarte, Jéssica Nayara Góes de Araújo, Ayda Maria Quirino Silva Dos Santos, Juliana Marinho de Oliveira, Maria Sanali Moura Oliveira Paiva, Adriana Augusto Rezende, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata, Karla Danielly da Silva Ribeiro, André Ducati Luchessi, Vivian Nogueira Silbiger
Background and aims : Fat-soluble vitamins play an important role in the pathogenesis of cardiovascular disease and progression of atherosclerosis. This study aimed at investigating the relationship of the serum levels of alpha-tocopherol and retinol with the extent of coronary lesions in patients with coronary artery disease. Methods . Patients with coronary artery disease ( n =177) aged 30-74 years, who underwent their first coronary angiography, were enrolled. The extent of coronary lesions was assessed using the Friesinger index (FI)...
2018: Journal of Nutrition and Metabolism
Wissam Zam
Background: Turmeric is a spice that has recently received much interest and has been widely used in Ayurvedic medicine. Turmeric products are diarylheptanoids and have been characterized as safe. They are termed as curcuminoids that consists essentially of three major compounds: curcumin, demethoxycurcumin, and bisdemethoxycurcumin. Curcumin is a lipophilic polyphenol that has poor systemic bioavailability and suffers from biotransformation by human intestinal microflora to yield different metabolites that are easily conjugated to glucuronides and sulfate O-conjugated derivatives...
2018: Journal of Nutrition and Metabolism
Muluken Dubale Mamoro, Lolemo Kelbiso Hanfore
Background: Tetanus toxoid immunization is one of the proven strategies for eliminating maternal and neonatal tetanus. According to Ethiopian Demographic Health Survey of 2016, only 49% of mothers received two tetanus toxoid (TT) injections during their last pregnancy which is below the World Health Organization and Ethiopia Ministry of Health recommendation. Therefore, the aim of this study was to determine the status of TT immunization among mothers in Damboya Woreda, South Ethiopia...
2018: Journal of Nutrition and Metabolism
Muhammad Ibrahim, Maryam Abimbola Mikail, Idris Adewale Ahmed, Radiah Abdul Ghani
Purpose: Cardiovascular disease (CVD) is the leading and the most critical type of chronic disease. Atherosclerosis is the most common cause of CVD. Inflammation has been progressively acknowledged as a vital and central player in the pathophysiology of atherosclerosis. Baccaurea angulata is an underutilized fruit of the island of Borneo. It was obtained from Bau, Sarawak, Malaysia. In our previous studies, B. angulata did not only increase antioxidant enzyme activities, but also slowed the lipid peroxidation process in high-cholesterol-fed rabbits...
2018: Journal of Nutrition and Metabolism
Joyce Nankumbi, Tom Dennis Ngabirano, Gorrette Nalwadda
Maternal nutrition during pregnancy affects the health of the mother and baby. The objective of this paper is to describe the maternal nutrition education offered by midwives to women attending an antenatal clinic. The study also examined the resources, support, and the needs of the midwives in offering the nutrition education. Six in-depth interviews with the midwives, six direct structured observations of the group education, and 12 one-on-one interactions of midwife and pregnant women observations were completed...
2018: Journal of Nutrition and Metabolism
David Oscar Yawson, Michael Osei Adu, Benjamin Ason, Frederick Ato Armah, Emmanuel Boateng, Reggie Quansah
The World Health Organization (WHO) has highlighted the beneficial role of adequate intake of potassium (K) in combating the global burden of noncommunicable diseases (NCDs), mainly hypertension and cardiovascular diseases. Diets are the main source of K supply to humans and can contribute to both K deficiency (hypokalemia) and excess (hyperkalemia). While global attention is currently devoted to K deficiency, K excess can be even more dangerous and deserves equal attention. The objectives of this paper were to (i) estimate the K intake of Ghanaian population using food supply and food composition data and (ii) compare this estimate with the WHO-recommended requirement for K in order to assess if there is a risk of inadequate or excess K intake...
2018: Journal of Nutrition and Metabolism
Blake A Niccum, Daniel J Stein, Brian W Behm, R Ann Hays
Background: Fecal microbiota transplant (FMT) is an effective therapy for recurrent Clostridium difficile infection (CDI). However, in 12% of patients treated with FMT, CDI recurs within one month. Zinc deficiency predicts increased diarrheal frequency in malnourished children, but little is known about its association with FMT outcome. We hypothesized that zinc levels were an independent predictor of CDI recurrence after FMT. Methods: We performed a retrospective cohort study of 80 patients (mean age, 66; 59 women) receiving FMT for CDI from 9/2013-9/2016 at a tertiary care center...
2018: Journal of Nutrition and Metabolism
Amare Lisanu Mazengia, Gashaw Andargie Biks
Background: Stunting is a major public health problem in most developing countries, and it increases the risk of illness and death throughout childhood. It is also a major public health problem in Ethiopia. Most of the few studies done in Ethiopia were done in schools. However, the prevalence of stunting of school-age children at the community level is largely unknown. Objective: To assess prevalence and predictors of stunting among school-age children in Mecha District, Amhara Regional State, Ethiopia...
2018: Journal of Nutrition and Metabolism
Karen L Sweazea, Carol S Johnston, Brendan Miller, Eric Gumpricht
Nitric oxide (NO) is a primary vasodilatory factor released from endothelial cells of the peripheral vasculature. NO production is stimulated through enzymatic-dependent mechanisms via NO synthase and from dietary intake of nitrate-containing foods or supplements. We evaluated the efficacy of a nitrate-rich fruit and vegetable liquid supplement (FVS, AMPED NOx, Isagenix International LLC) versus a juice low in nitrates (prune juice, PRU) on circulating nitrates/nitrites as well as cardiovascular parameters in 45 healthy normotensive men (18-40 y)...
2018: Journal of Nutrition and Metabolism
Shelly N Hester, Angela Mastaloudis, Russell Gray, Joseph M Antony, Mal Evans, Steven M Wood
Background: Anthocyanins and prebiotics impact overall health and wellness, likely through modulation of the microbiota and the intestinal ecosystem. Objectives: An 8-week open-label study in male and female volunteers with uncomplicated obesity was designed to study the efficacy of an anthocyanin and prebiotic blend in modulating intestinal microbiota and intestinal inflammation. Results: After 8 weeks of daily supplementation, participants had a significant decrease in Firmicutes ( p < 0...
2018: Journal of Nutrition and Metabolism
Ina Knerr, Laurie Bernstein, Ellen Crushell, Siobhan O'Sullivan, Jörn Oliver Sass
No abstract text is available yet for this article.
2018: Journal of Nutrition and Metabolism
Andréia Quatrin, Lisiane Conte, Dariane Trivisiol da Silva, Cassieli Gehlen Figueiredo, Sabrina Somacal, Miguel Roehrs, Cibele Ferreira Teixeira, Fernanda Barbisan, Paula Rossini Augusti, Mário Roberto Maróstica Júnior, Ivana Beatrice Mânica da Cruz, Tatiana Emanuelli
Jaboticaba peel powder (JPP) is rich in bioactive compounds, mainly soluble and insoluble polyphenols with great antioxidant properties. The aim of this study is to evaluate the effects of JPP supplementation on the oxidative stress and hepatic damage in a rat model of type 2 diabetes mellitus (T2DM). Diabetic rats received vehicle or JPP at 2.7 (JPP-I), 5.4 (JPP-II), or 10.8 (JPP-III) g/L in drinking water during 8 weeks. JPP-III attenuated hyperglycaemia and dyslipidemia increased by 86% the liver content of nonprotein thiol groups and by 90% the GSH/GSSG ratio by activating glutathione synthesis...
2018: Journal of Nutrition and Metabolism
Kulapong Jayanama, Supanee Putadechakun, Praopilad Srisuwarn, Sakda Arj-Ong Vallibhakara, Prapimporn Chattranukulchai Shantavasinkul, Chanika Sritara, Surasak Kantachuvesiri, Surat Komindr
Background: Body composition measurement is very important for early nutritional care in hemodialysis patients. Dual-energy X-ray absorptiometry (DXA) is a gold standard test, but clinically limited. Bioelectrical impedance analysis (BIA) with multifrequency technique is a practical and reliable tool. Objective: This cross-sectional study was aimed to compare the agreement of BIA with DXA in measurement of body composition in hemodialysis patients and to evaluate their associated factors...
2018: Journal of Nutrition and Metabolism
Naima Saeid, Mohammed Elmzibri, Abdeslam Hamrani, Qandoussi Latifa, Hakim Belghiti, Hicham El Berri, Kaoutar Benjeddou, Amina Bouziani, Hasnae Benkirane, Youness Taboz, Asmae Elhamdouchi, Khalid El Kari, Hassan Aguenaou
Background: The incidence of noncommunicable diseases (NCDs) has greatly increased, mainly due to high level of dietary sodium. Thus, reduction of sodium intake in population has been recognized as one of the most cost-effective strategies to reduce NCDs. The aim of this study was to estimate sodium and potassium consumption in a sample of Moroccan children as a baseline study to implement national strategy for salt intake reduction. Methods: The study was conducted on 131 children aged 6-18 years recruited from Rabat and its region...
2018: Journal of Nutrition and Metabolism
Fatima Barich, Fatima Ezzahra Zahrou, Fatima Zahra Laamiri, Nisrine El Mir, Manelle Rjimati, Amina Barkat, El Arbi Rjimati, Hassan Aguenaou
Worldwide, obesity is considered as an important public health problem. This study aims to explore the social and economic factors associated with overweight and obesity among women of childbearing age residing in the urban area of Morocco. This is a descriptive and analytical study conducted among women ( N =240), aged between 15 and 49 years. At recruitment, socioeconomic status (SES) of each participant was assessed, anthropometric parameters were recorded, and body mass index (BMI), waist circumference, and waist-to-hip ratio (WHR) were measured to assess overweight and obesity...
2018: Journal of Nutrition and Metabolism
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