Veronika Jurakova, Veronika Farková, Jiri Kucera, Katerina Dadakova, Martina Zapletalova, Katerina Paskova, Roman Reminek, Zdenek Glatz, Lydie Izakovicova Holla, Filip Ruzicka, Jan Lochman, Petra Borilova Linhartova
Recent RNA sequencing studies have given us a deeper insight into the cariogenic impact of carbohydrate sources in the bacterium Streptococcus mutans, the principal microbial agent in dental caries etiopathogenesis. The process of dental caries development is facilitated by the ability of this bacterium to ferment some carbohydrates into organic acids contributing to a pH decrease in the oral cavity and the demineralization of the hard tissues of the tooth. Furthermore, in dental caries progression, biofilm formation, which starts and ends with free planktonic cells, plays an important role and has several unique properties called virulence factors...
July 13, 2023: Molecular Oral Microbiology