Domenico Dell'edera, Annunziata Anna Epifania, Giusi Natalia Milazzo, Manuela Leo, Carmela Santacesaria, Arianna Allegretti, Eleonora Mazzone, Paolo Panetta, Giovanna Iammarino, Maria Giovanna Lupo, Rocchina Barbieri, Maria Brigida Lioi
INTRODUCTION: hemoglobinopathies constitute a major health problem worldwide. These disorders are characterized by a clinical and hematological phenotypic heterogeneity. The increase of HbA2 is an invaluable hematological marker of the beta-thalassemia heterozygosis and of double heterozygosis for the alleles of delta and alpha globin genes or for the alleles of delta and beta globin genes which can cause the increase of HbA2 up to normal or borderline values. CASE REPORT: we report the case of a 30-year-old woman (first pregnant) who was admitted to our Unit at 12 weeks for a screening for thalassemia...
October 2013: Journal of Prenatal Medicine