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Journal of Cancer Epidemiology

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https://read.qxmd.com/read/30936917/stagnation-in-decreasing-gastric-cancer-incidence-and-mortality-in-quito-time-trend-analysis-1985-2013
#1
Wilmer Tarupi, Esther de Vries, Patricia Cueva, José Yépez
Background: Despite the significant global decline in mortality and incidence, gastric cancer (GC) remains a very common cause of illness and death in the Latin American region. This article seeks to describe, in depth, the time trend of incidence and mortality of GC in the city of Quito, from 1985 to 2013. Methods: Using data from the Quito Cancer Registry, annual sex-specific age-standardized incidence and mortality rates were calculated. The analysis included all types of GC together, as well as by histological subtype...
2019: Journal of Cancer Epidemiology
https://read.qxmd.com/read/30804999/use-of-mastectomy-for-overdiagnosed-breast-cancer-in-the-united-states-analysis-of-the-seer-9-cancer-registries
#2
C Harding, F Pompei, D Burmistrov, R Wilson
Aim: We investigated use of mastectomy as treatment for early breast cancer in the US and applied the resulting information to estimate the minimum and maximum rates at which mastectomy could plausibly be undergone by patients with overdiagnosed breast cancer. Little is currently known about overtreatments undergone by overdiagnosed patients. Methods: In the US, screening is often recommended at ages ≥40. The study population was women age ≥40 diagnosed with breast cancer in the US SEER 9 cancer registries during 2013 (n=26,017)...
2019: Journal of Cancer Epidemiology
https://read.qxmd.com/read/30733803/hpv-chlamydial-coinfection-prevalence-and-association-with-cervical-intraepithelial-lesions-a-pilot-study-at-mbarara-regional-referral-hospital
#3
Frank Ssedyabane, Diaz Anaya Amnia, Ronald Mayanja, Aisagbonhi Omonigho, Charles Ssuuna, Josephine Nambi Najjuma, Bwanga Freddie
Background: Human Pappilloma Virus (HPV) is the necessary cause of cervical cancer. A number of risk factors are believed to influence the role of HPV in the development of cervical cancer. This is so because majority of HPV infections are cleared and only a few are able to result into cancer. Chlamydia trachomatis (CT) is considered a potential cofactor in the development of cervical intraepithelial neoplasia (CIN), although different studies have produced contradicting information (Silins et al ...
2019: Journal of Cancer Epidemiology
https://read.qxmd.com/read/30713554/a-community-based-assessment-of-knowledge-and-practice-of-breast-self-examination-and-prevalence-of-breast-disease-in-southwest-cameroon
#4
Kareen Azemfac, S Ariane Christie, Melissa M Carvalho, Theophile Nana, Ahmed N Fonje, Gregory Halle-Ekane, Rochelle Dicker, Alain Chichom-Mefire, Catherine Juillard
Introduction: Despite the rising trend in breast cancer incidence and mortality across Sub-Saharan Africa, there remains a critical knowledge gap about the burden and patterns of breast disease and breast cancer screening practices at the population level. This study aimed to identify socioeconomic factors associated with knowledge and practice of breast self-examination (BSE) as well as assess the prevalence of breast disease symptoms among a mixed urban-rural population of women in the Southwest region of Cameroon...
2019: Journal of Cancer Epidemiology
https://read.qxmd.com/read/30675163/trends-in-incidence-of-two-major-subtypes-of-liver-and-bile-duct-cancer-hepatocellular-carcinoma-and-cholangiocarcinoma-in-songkhla-southern-thailand-1989-2030
#5
Seesai Yeesoonsang, Edward McNeil, Shama Virani, Surichai Bilheem, Chakrarat Pittayawonganon, Chuleeporn Jiraphongsa, Hutcha Sriplung
Background: The incidence of liver and bile duct cancer continues to rise, especially in Thailand. We aimed to project the trends in incidence of this rare but lethal cancer in southern Thailand in order to determine its future disease burden. Methods: Gender-specific trends in age-standardized incidence rates per 100,000 person-years for hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) cases in Songkhla province of southern Thailand diagnosed between 1989 and 2013 were estimated and projected up to year 2030 using three different modeling techniques: a joinpoint model, an age-period-cohort model, and a modified age-period-cohort model...
2018: Journal of Cancer Epidemiology
https://read.qxmd.com/read/30416523/the-epidemiology-and-trend-of-cancer-in-jordan-2000-2013
#6
Yousef S Khader, Ghazi F Sharkas, Kamal H Arkoub, Mahmoud A Alfaqih, Omar F Nimri, Albaraa M Khader
Objectives: This study aimed to determine the overall incidence, trend, and epidemiology of cancer among Jordanians from 2000 to 2013 using data extracted from Jordan's Cancer Registry (JCR). Methods: All cancer cases among Jordanians registered between 2000 and 2013 were analyzed using CanReg software and SPSS. The overall crude incidence rates (CIRs) and the age standardized rates (ASRs) of cancer per 100,000 were calculated. Results: A total of 58788 cancer cases were registered during the period 2000-2013...
2018: Journal of Cancer Epidemiology
https://read.qxmd.com/read/30105053/role-of-the-mechanisms-of-detection-in-the-increased-risk-of-thyroid-cancer-a-retrospective-cohort-study-in-an-hmo-in-buenos-aires
#7
María Fabiana Russo Picasso, Jimena Vicens, Carina Giuliani, Ana Del Valle Jaén, Carmen Cabezón, Marcelo Figari, Ana María Gómez Saldaño, Silvana Figar
Background: Two hypotheses attempt to explain the increase of thyroid cancer (TC) incidence: overdetection by excessive diagnostic scrutiny and a true increase in new cases brought about by environmental factors. Changes in the mechanism of detection and the risk of incidentally diagnosed TC could result in an increase of TC incidence. Methods: Retrospective cohort study. We identified incident cases of TC from the pathological reports of patients in a HMO and review of clinical records...
2018: Journal of Cancer Epidemiology
https://read.qxmd.com/read/29973955/effects-of-different-treatment-strategies-and-tumor-stage-on-survival-of-patients-with-advanced-laryngeal-carcinoma-a-15-year-cohort-study
#8
Nima Daneshi, Mohammad Fararouei, Mohammad Mohammadianpanah, Mohammad Zare-Bandamiri, Somayeh Parvin, Mostafa Dianatinasab
Background: Laryngeal cancer is the second most common cancer in the head and neck. Since laryngeal cancer management is a complex process, there is still no standard strategy to treat this disease in order to increase the survival rate of the patients especially among those with advanced form of the disease. Methods: A cohort study was undertaken to analyze factors predicting survival of the patients in advanced stage laryngeal cancer in the Southern Iran among all patients newly diagnosed with laryngeal cancer between 2000 and 2015...
2018: Journal of Cancer Epidemiology
https://read.qxmd.com/read/29861727/validity-of-administrative-databases-in-comparison-to-medical-charts-for-breast-cancer-treatment-data
#9
Ashini Weerasinghe, Courtney R Smith, Vicky Majpruz, Anjali Pandya, Kristina M Blackmore, Claire M B Holloway, Roanne Segal-Nadlere, Cathy Paroschy Harris, Ashley Hendry, Amanda Hey, Anat Kornecki, George Lougheed, Barbara-Anne Maier, Patricia Marchand, David McCready, Carol Rand, Simon Raphael, Neelu Sehgal, Anna M Chiarelli
Objective: Medical chart abstraction is the gold standard for collecting breast cancer treatment data for monitoring and research. A less costly alternative is the use of administrative databases. This study will evaluate administrative data in comparison to medical charts for breast cancer treatment information. Study Design and Setting: A retrospective cohort design identified 2,401 women in the Ontario Breast Screening Program diagnosed with invasive breast cancer from 2006 to 2009...
2018: Journal of Cancer Epidemiology
https://read.qxmd.com/read/29056966/endocrine-therapy-initiation-among-older-women-with-ductal-carcinoma-in-situ
#10
Chelsea Anderson, Aaron N Winn, Stacie B Dusetzina, Hazel B Nichols
BACKGROUND: Although treatment of ductal carcinoma in situ (DCIS) is controversial, national guidelines recommend considering endocrine therapy for women with estrogen receptor- (ER-) positive DCIS or those undergoing breast conserving surgery (BCS) without radiation. We evaluated uptake and predictors of endocrine therapy use among older women with DCIS. METHODS: In the SEER-Medicare database, we identified women aged 65+ years diagnosed with DCIS during 2007-2011...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28894467/racial-and-socioeconomic-disparities-are-more-pronounced-in-inflammatory-breast-cancer-than-other-breast-cancers
#11
Ryan A Denu, John M Hampton, Adam Currey, Roger T Anderson, Rosemary D Cress, Steven T Fleming, Joseph Lipscomb, Xiao-Cheng Wu, J Frank Wilson, Amy Trentham-Dietz
Inflammatory breast cancer (IBC) is a rare yet aggressive form of breast cancer. We examined differences in patient demographics and outcomes in IBC compared to locally advanced breast cancer (LABC) and all other breast cancer patients from the Breast and Prostate Cancer Data Quality and Patterns of Care Study (POC-BP), containing information from cancer registries in seven states. Out of 7,624 cases of invasive carcinoma, IBC and LABC accounted for 2.2% (N = 170) and 4.9% (N = 375), respectively. IBC patients were more likely to have a higher number (P = 0...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28744312/prevalence-of-egfr-mutations-in-lung-cancer-in-uruguayan-population
#12
Nora Berois, Diego Touya, Luis Ubillos, Bernardo Bertoni, Eduardo Osinaga, Mario Varangot
BACKGROUND: Incorporation of molecular analysis of the epidermal growth factor receptor (EGFR) gene into routine clinical practice represents a milestone for personalized therapy of the non-small-cell lung cancer (NSCLC). However, the genetic testing of EGFR mutations has not yet become a routine clinical practice in developing countries. In view of different prevalence of such mutations among different ethnicities and geographic regions, as well as the limited existing data from Latin America, our aim was to study the frequency of major types of activating mutations of the EGFR gene in NSCLC patients from Uruguay...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28702054/the-role-of-neighborhood-characteristics-in-late-stage-melanoma-diagnosis-among-hispanic-men-in-california-texas-and-florida-1996-2012
#13
Valerie M Harvey, Clinton W Enos, Jarvis T Chen, Hadiza Galadima, Karl Eschbach
BACKGROUND: Hispanics diagnosed with cutaneous melanoma are more likely to present at advanced stages but the reasons for this are unknown. We identify census tracts at high risk for late stage melanoma diagnosis (LSMD) and examine the contextual predictors of LSMD in California, Texas, and Florida. METHODS: We conducted a cross-sectional study using geocoded state cancer registry data. Using hierarchical multilevel logistic regression models we estimated ORs and 95% confidence intervals for the impact of socioeconomic, Hispanic ethnic concentration, index of dissimilarity, and health resource availability measures on LSMD...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28487737/insurance-status-is-related-to-receipt-of-therapy-and-survival-in-patients-with-early-stage-pancreatic-exocrine-carcinoma
#14
Emily Boevers, Bradley D McDowell, Sarah L Mott, Anna M Button, Charles F Lynch
Objectives. The study objective was to determine how insurance status relates to treatment receipt and overall survival for patients with early-stage pancreatic exocrine carcinoma. Methods. SEER data were evaluated for 17,234 patients diagnosed with Stage I/II pancreatic exocrine carcinoma. Multivariate regression models controlled for personal characteristics to determine whether insurance status was independently associated with overall survival and receipt of radiation/surgery. Results. Odds of receiving radiation were 1...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28484492/relationships-between-global-dna-methylation-in-circulating-white-blood-cells-and-breast-cancer-risk-factors
#15
REVIEW
Nayha Chopra-Tandon, Haotian Wu, Kathleen F Arcaro, Susan R Sturgeon
It is not yet clear whether white blood cell DNA global methylation is associated with breast cancer risk. In this review we examine the relationships between multiple breast cancer risk factors and three markers of global DNA methylation: LINE-1, 5-mdC, and Alu. A literature search was conducted using Pubmed up to April 1, 2016, using combinations of relevant outcomes such as "WBC methylation," "blood methylation," "blood LINE-1 methylation," and a comprehensive list of known and suspected breast cancer risk factors...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28321255/cancer-prevention-in-low-and-middle-income-countries
#16
EDITORIAL
Subhojit Dey, Preet K Dhillon, Preetha Rajaraman
No abstract text is available yet for this article.
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28239395/patterns-of-sociodemographic-and-clinicopathologic-characteristics-of-stages-ii-and-iii-colorectal-cancer-patients-by-age-examining-potential-mechanisms-of-young-onset-disease
#17
Caitlin C Murphy, Hanna K Sanoff, Karyn B Stitzenberg, John A Baron, Jennifer L Lund, Robert S Sandler
Background and Aims. As a first step toward understanding the increasing incidence of colorectal cancer (CRC) in younger (age < 50) populations, we examined demographic, clinicopathologic, and socioeconomic characteristics and treatment receipt in a population-based sample of patients newly diagnosed with stages II and III CRC. Methods. Patients were sampled from the National Cancer Institute's Patterns of Care studies in 1990/91, 1995, 2000, 2005, and 2010 (n = 6, 862). Tumor characteristics and treatment data were obtained through medical record review and physician verification...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28133481/a-case-control-study-of-risk-factors-for-salivary-gland-cancer-in-canada
#18
Sai Yi Pan, Margaret de Groh, Howard Morrison
Aim. To assess the effect of various lifestyle risk factors on the risk of salivary gland cancer in Canada using data from a population-based case-control study. Methods. Data from a population-based case-control study of 132 incident cases of salivary gland cancer and 3076 population controls were collected through self-administered questionnaire and analysed using unconditional logistic regression. Results. Four or more servings/week of processed meat product was associated with an adjusted odds ratio (OR) and corresponding 95% confidence interval (CI) of 1...
2017: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28070189/role-of-private-enterprise-in-cancer-control-in-low-to-middle-income-countries
#19
REVIEW
Chukwumere E Nwogu, Martin Mahoney, Ifeoma Okoye, Kenneth Ejiogu, Saby George, Grace Dy, Mutiu Jimoh, Omolola Salako, Oge Ilegbune, Bindiya Chugani, Emmanuel Ezeome, Abiodun O Popoola, Arthur M Michalek
Background. About 65% of cancer deaths globally occur in low to middle income countries (LMICs) where prioritization and allocation of resources to cancer care are often quite poor. In the absence of governmental focus on this problem, public-private partnerships may be an avenue to provide effective cancer control. Methods. This manuscript highlights the establishment of a nongovernmental organization (NGO) to stimulate the development of partnerships between oncology professionals, private enterprise, and academic institutions, both locally and internationally...
2016: Journal of Cancer Epidemiology
https://read.qxmd.com/read/28018431/genetic-and-clinical-features-of-medullary-thyroid-carcinoma-the-experience-of-a-single-center-in-costa-rica
#20
Javier Calvo, Gabriel Torrealba, Adriana Sáenz, Carlos Santamaría, Estela Morera, Silvia Alvarado, Yolanda Roa, Michelle González
Background. Activating mutations in the RET gene leads to medullary thyroid carcinoma (MTC). Guidelines encourage performing RET analysis in subjects with hereditary and sporadic disease. Materials and Methods. Design. Observational, case series report study. Patients. Subjects diagnosed with MTC, with a thyroidectomy performed in a single center in Costa Rica between the years 2006 and 2015. Diagnosis and Follow-Up. Pre- and postoperative calcitonin, RET mutation, and neck ultrasound and tomography were obtained...
2016: Journal of Cancer Epidemiology
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