Read by QxMD icon Read

Journal of Clinical and Aesthetic Dermatology

Jolie Krooks, Angela Weatherall, Stuart Markowitz
A 70-year-old, immunocompetent male presented with mildly painful and pruritic erythematous patches and vesicles on the right dorsal aspect of the distal middle finger present for four weeks. Other skin lesions or systemic symptoms were notably absent. The patient failed to respond to valacyclovir, topical triamcinolone acetonide ointment, trimethoprim-sulfamethoxazole, and cephalexin for presumptive diagnoses of recurrent herpetic whitlow, dyshidrotic eczema, and blistering distal dactylitis, respectively...
December 2018: Journal of Clinical and Aesthetic Dermatology
Monica Janeczek, Lauren Moy, Eden P Lake, James Swan
Background: Due to the emerging trend of alternative medicine, patients inquire about natural remedies to alleviate their symptoms. Dermatologists should be aware of the efficacy and safety of topical botanical treatments available on the market. Mahonia aquifolium, native to the United States, has been recently shown to have anti-inflammatory properties useful in cutaneous disorders. Objective: Our aim was to review clinical trials that assess the efficacy and safety of Mahonia aquifolium in cutaneous disorders...
December 2018: Journal of Clinical and Aesthetic Dermatology
Jordan V Wang, Nazanin Saedi
Dermatology is a medical specialty that is favorable to operating in private practice settings. Without the administrative oversight from a larger organization, there are greater responsibilities for business administration, including risk identification and management. Here, we discuss salient examples from major categories of enterprise risk in order to introduce a framework that clinicians can utilize. Implementing a comprehensive risk management plan can help to prevent and reduce losses in a private practice dermatology clinic...
December 2018: Journal of Clinical and Aesthetic Dermatology
Joan Vandeputte
Objective: Hyaluronic acid (HA) volumizer injection into subcutaneous and deep tissue layers is increasingly used for nonsurgical volume loss correction. Information on optimal techniques, safety, and medium- to long-term satisfaction is limited. This study evaluated cohesive polydensified matrix® HA volumizer CPM-26 (Modélis® Shape or Belotero® Volume) across different indications. Design: This study was a retrospective chart review and included a patient questionnaire given at six months posttreatment and during long-term assessment (mean: 3...
December 2018: Journal of Clinical and Aesthetic Dermatology
Ruri D Pamela
Background: Chronic exposure to solar ultraviolet irradiation can result in facial fine lines and wrinkles, poor texture, and sagging skin. Growth factors are polypeptides or proteins that play a key role in the regulation of a number of physiological processes. Topical application of growth factors also reduces signs of photoaging, promotes fibroblast and keratinocyte proliferation, and induces extracellular matrix formation. Objective: This study evaluated the efficacy of topical growth factor after microneedling treatment for the reduction of visual signs of facial photoaging in Fitzpatrick skin types III to IV...
December 2018: Journal of Clinical and Aesthetic Dermatology
Abrahem Kazemi, Olabola Awosika, Cheryl Burgess
A 77-year-old African American woman presented to the dermatologist with two pruritic lumps in her right breast. She reported traveling to Mexico on a cruise ship two years prior to the onset of her lesions, but denied a history of previous breast masses or malignancy. Despite former radiographic evaluation by her internist revealing benign growths, and despite dermatologic treatment with intralesional steroid injections, a third new, firm nodule developed in her right breast. One such nodule eventually formed into an ulcer, and a punch biopsy revealed thin-walled vascular channels in loose inflamed stroma, coarse fibrosis, calcareous corpuscles, and an elongated parasite...
December 2018: Journal of Clinical and Aesthetic Dermatology
Lily Jiang, Peter D Hino, Ashish Bhatia, Thomas J Stephens, Felipe Jimenez
Background: Melasma is a common, persistent disorder of hyperpigmented facial skin predominantly attributed to ultraviolet light exposure, hormonal influences, and genetic predisposition. Objectives: This double-blind, placebo-controlled, randomized clinical trial was conducted to assess the efficacy and tolerance of a multimodality night cream when used over a course of 24 weeks followed by a four-week regression in female subjects with moderate to severe melasma, presence of solar lentigines, and periocular lines and wrinkles...
December 2018: Journal of Clinical and Aesthetic Dermatology
Francine Santoro, Sandrine Teissedre
Objective: We assessed whether Cetaphil Redness Control Night Cream (CRCNC; Galderma Laboratories, Fort Worth, Texas) improves electrical capacitance (EC) and transepidermal water loss (TEWL) in healthy subjects with dry skin and determined efficacy and tolerability in subjects with rosacea. Study design: The present study included two independent, open-label investigations: in the first, EC and TEWL were measured at baseline and at two, four, eight, and 24 hours after one application of CRCNC to dry skin; in the second, an evaluation of once-daily CRCNC application for 22 days using a chromameter, image analysis, and trained rater was performed, with patient evaluations at baseline and Days 1, 8, and 22 collected...
December 2018: Journal of Clinical and Aesthetic Dermatology
Taraneh Yazdanparast, Saman Ahmad Nasrollahi, Leila Izadi Firouzabadi, Alireza Firooz
Background: Contact dermatitis is a common skin condition observed by dermatologists, presenting a burden on healthcare systems. Recently, there has been a trend in producing skin-identical topical preparations for the repair of skin. However, there is a limited number of experimental studies to assess the safety and efficacy of this products. Objective: This study assessed the clinical efficacy and safety of a skin-identical ceramide complex cream (Dermalex Repair Contact Eczema; Omega Pharma, Nazareth, Belgium) in the treatment of contact dermatitis...
November 2018: Journal of Clinical and Aesthetic Dermatology
James Q Del Rosso, Neal Bhatia
In-vitro and in-vivo studies have supported antimicrobial, anti-inflammatory, and other biologic properties of hypochlorous acid (HOCl), which has led to its use in the treatment of skin wounds, pruritus, diabetic ulcers, and some inflammatory skin disorders. Research has also shown that the physiochemical properties of HOCl after application to skin are highly dependent on both pH and formulation stability. In this review, the authors discuss a core HOCI formulation (Microcyn® Technology, Sonoma Pharmaceuticals, Petaluma, California) that is stable for up to two years, noncytotoxic, and pH-neutralized to augment therapeutic activity, skin tolerability, and stability...
November 2018: Journal of Clinical and Aesthetic Dermatology
Andrew Alexis, James Q Del Rosso, Seemal R Desai, Jeanine B Downie, Zoe Diana Draelos, Christina Feser, Rion Forconi, Joseph F Fowler, Michael Gold, Joely Kaufman-Janette, Edward Lain, Mark Lee, Mark Ling, Ava T Shamban, Wm Philip Werschler, Annamarie Daniels
Background and objectives: Acne vulgaris is a highly prevalent and multifactorial skin disorder that can adversely impact health-related quality of life. Factors that contribute to the pathogenesis of acne include pilosebaceous proliferation of proinflammatory Propionibacterium acnes ( P. acnes ) bacteria, presence of circulating androgens, excess sebum production, abnormal follicular keratinization, and multiple inflammatory cascades. Oral tetracyclines-especially doxycycline and minocycline-are frequently prescribed for the treatment of moderate-to-severe acne, given their anti-inflammatory properties and their effect on P...
November 2018: Journal of Clinical and Aesthetic Dermatology
Celine Couteau, Eva Paparis, Laurence Coiffard
Background: In patients undergoing chemotherapy, the application of nail polish and/or a colorless base coat is recommended in order to prevent the adverse effects that can occur on the nails throughout treatment. Objective: In this study, the photoprotective effects of different clear nail polishes were examined. Methods: Twelve commercially available, colorless nail products were tested in vitro . Two layers of the product were applied, as recommended to patients, on polymethyl methacrylate (PMMA) plates...
November 2018: Journal of Clinical and Aesthetic Dermatology
Neal D Bhatia, David M Pariser, Leon Kircik, Tina Lin, Susan Harris, Lindsey Mathew, Radhakrishnan Pillai
Background: Topical corticosteroids (TCS) represent a mainstay of psoriasis treatment, though more potent formulations are not recommended for use for more than 2 to 4 weeks. Objective: We sought to investigate the safety and efficacy of once-daily halobetasol propionate 0.01%/tazarotene 0.045% (HP/TAZ) lotion and halobetasol propionate 0.05% cream in patients with moderate-to-severe plaque psoriasis. Methods: This was a multicenter, randomized, double-blind, parallel-group, vehicle-controlled Phase II study (n=154)...
November 2018: Journal of Clinical and Aesthetic Dermatology
James G Ravin, Amit Om
No abstract text is available yet for this article.
November 2018: Journal of Clinical and Aesthetic Dermatology
Eftychia Platsidaki, Varvara Vasalou, Maria Gerodimou, Vasiliki Markantoni, Anargyros Kouris, Eleftheria Vryzaki, Stamatis Gregoriou, Dimitrios Rigopoulos, Georgios Kontochristopoulos
Background: Skin tags (STs) are benign skin lesions. Their definite etiology remains unknown. We aim to examine the association of obesity, diabetes mellitus, hyperlipidemia, thyroid abnormalities, acanthosis nigricans, and multiple STs in a Greek primary population. Methods: Phototype and body weight were recorded. Fasting serum blood samples were analyzed for cholesterol, low-density lipoprotein, high-density lipoprotein, triglycerides, glucose, and thyroid-stimulating hormone. Univariate ordinal logistic regression multivariate analysis was performed...
October 2018: Journal of Clinical and Aesthetic Dermatology
Feizollah Niazi, Seyed Hassan Hooshyar, Keshvad Hedayatyanfard, Seyed Ali Ziai, Farideh Doroodgar, Sana Niazi, Behnam Habibi, Ali Asadirad
Background: Keloid and hypertrophic scars (HTS) are formed by excessive collagen formation. Angiotensin II, through the AT1 receptor, plays an important role in extracellular matrix production. However, less is known about angiotensin II and AT1 receptor concentrations in HTS and keloid tissues. Objective: The purpose of this study was to determine the angiotensin II and AT1 receptor concentrations in keloid, HTS, and normal skin tissues. Methods: Skin biopsy samples from patients with HTS (n=26), keloid (n=20), and normal (n=30) skin tissues were evaluated for angiotensin II and AT1 receptor concentrations by use of the enzyme-linked immunosorbent assay technique...
October 2018: Journal of Clinical and Aesthetic Dermatology
Naser Owji, Behzad Khademi, Mohammadreza Khalili
Objectives: Topical onion extract gel is commonly used in commercial anti-scar medications. The purpose of this study was to evaluate the effectiveness of topical onion extract gel on the appearance of blepharoplasty scars and to compare the results of its use to those of petroleum jelly. Design: The participants enrolled in this prospective, double-blind study were randomly treated with either topical onion extract gel or petroleum jelly. The products were applied twice daily for two months following suture removal...
October 2018: Journal of Clinical and Aesthetic Dermatology
Thomas J Stephens, Michael Babcock, Vivian Bucay, Vincent Gotz
Background: The gold standard for the treatment of hyperpigmentation is hydroquinone (HQ), which has been available as a skin lightener for more than 50 years. Numerous clinical studies have proven its efficacy in various topical formulations. In the United States, HQ is available as a nonprescription product in 2% formulations and as a 4% prescription product. Objective: This study compared the safety and efficacy of a 2% hydroquinone multi-ingredient foam with a standard 4% hydroquinone cream on photodamaged facial skin...
October 2018: Journal of Clinical and Aesthetic Dermatology
Caroline Vinkel, Simon Francis Thomsen
Hidradenitis suppurativa (HS), a relatively common and chronic inflammatory skin disorder. HS can have debilitating consequences if not diagnosed and treated appropriately. Clinically defined by recurrent, inflamed nodules in intertriginous regions (i.e., axillary, inguinal, and perianal areas), HS can cause intense pain and, in severe disease stages, lead to the formation of fistulas, sinus tracts, and extensive scarring. Postpubertal onset and female preponderance further characterize HS. Numerous pathogenic mechanisms have been proposed in HS, including immune dysregulation, genetics, smoking, and obesity; however, the exact etiology remains to be elucidated...
October 2018: Journal of Clinical and Aesthetic Dermatology
(no author information available yet)
No abstract text is available yet for this article.
October 2018: Journal of Clinical and Aesthetic Dermatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"