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Arthritis Care & Research

Marie Holmqvist
I appreciate the interesting review of corticosteroids and their impact on risk of venous thromboembolic events provided by Dr Parperis and associates. Corticosteroid use and its impact on comorbidities should definitely be closely followed in clinical practice. This article is protected by copyright. All rights reserved.
February 15, 2019: Arthritis Care & Research
Aimée Wattiaux, Brittany Bettendorf, Laura Block, Andrea Gilmore-Bykovskyi, Edmond Ramly, Megan E Piper, Ann Rosenthal, Jane Sadusky, Elizabeth Cox, Betty Chewning, Christie M Bartels
OBJECTIVE: Although smoking is a risk factor for cardiovascular and rheumatic disease severity, only 10% of rheumatology visits document cessation counseling. After implementing a rheumatology clinic protocol that increased tobacco quitline referrals 20-fold, current objectives were to 1) examine patients' barriers and facilitators to smoking cessation based on prior rheumatology experiences, 2) solicit reactions to the new cessation protocol, and 3) identify patient-centered outcomes or "signs of cessation progress" following improved care...
February 15, 2019: Arthritis Care & Research
Konstantinos Parperis
I read with great interest the article by Antovic et al, recently published in Arthritis Care & Research (1). In a population-based study, the investigators demonstrated an increased risk of venous thromboembolic events (VTE) in patients with idiopathic inflammatory myopathy (IIM), compared with the general population. Strikingly, the hazard ratio for VTE was 26.6 (95% CI 10.4, 68.0) the first year of diagnosis. The authors reported that 34.8% of patients with IIM versus 0.9% in the control group were taking glucocorticoids, however further data analysis might have been contacted in order to evaluate for possible association of glucocorticoid exposure and increased risk of VTE...
February 14, 2019: Arthritis Care & Research
Monique A M Gignac, Emma Irvin, Kim Cullen, Dwayne Van Eerd, Dorcas E Beaton, Quenby Mahood, Chris McLeod, Catherine L Backman
OBJECTIVE: To systematically review the evidence for an increased risk of osteoarthritis in the hip, knee, hand, wrist, finger, ankle, foot, shoulder, neck and spine related to men and women's diverse occupational activities and to examine dose response information related to the frequency, intensity, and duration of work exposures and the risk of OA. METHODS: Established guidelines for systematic reviews in occupational health and safety studies were followed. MEDLINE, EMBASE, CINAHL and Cochrane Library were searched from inception to December 2017...
February 14, 2019: Arthritis Care & Research
Brooke E Patterson, Adam G Culvenor, Christian J Barton, Ali Guermazi, Joshua J Stefanik, Kay M Crossley
OBJECTIVE: Persistent symptoms and poor quality of life (QoL) are common following anterior cruciate ligament reconstruction (ACLR). We aimed to determine the influence of a combined ACL injury (i.e., concomitant meniscectomy and/or arthroscopic chondral defect at the time of ACLR and/or secondary injury/surgery to ACLR knee) and MRI-defined cartilage defects, bone marrow lesions (BMLs) and meniscal lesions on patient-reported outcomes (PROs) 1- to 5-years post-ACLR METHODS: 80 participants (50 men) aged 32±14 years completed the Knee injury and OA Outcome Score (KOOS) and International Knee Documentation Committee (IKDC) questionnaire, and 3T MRI assessment at 1- and 5-years post-ACLR...
February 14, 2019: Arthritis Care & Research
Sizheng Zhao, Kazuki Yoshida, Gareth T Jones, David M Hughes, Sara K Tedeschi, Houchen Lyu, Robert J Moots, Daniel H Solomon, Nicola J Goodson
OBJECTIVE: Observational data facilitate examination of treatment-effect heterogeneity, but the risk of bias is substantial. We highlight methodological considerations through an analysis of whether smoking affects response to TNF inhibitors (TNFi) in axial spondyloarthritis (axSpA). METHODS: We used longitudinal data from the British Society for Rheumatology Biologics Register for Ankylosing Spondylitis. Participants fulfilling the ASAS criteria for axSpA, who started their first TNFi were eligible for analysis...
February 14, 2019: Arthritis Care & Research
Ernest R Vina, Michael J Hannon, Leslie R M Hausmann, Said A Ibrahim, Jazmin Dagnino, Andrea Arellano, C Kent Kwoh
OBJECTIVES: To determine the extent of ethnic differences in using exercise for therapy and Identify relevant modifiable determinants of exercise use among knee/hip osteoarthritis (OA) patients METHODS: Knee/hip OA study participants were identified. Surveys were administered to collect patient socio-demographics, clinical information, and beliefs and attitudes about providers and treatments. Final multivariable logistic regression models were created using a fully conditional method...
February 14, 2019: Arthritis Care & Research
Mia Glerup, Veronika Rypdal, Ellen Dalen Arnstad, Maria Ekelund, Suvi Peltoniemi, Kristiina Aalto, Marite Rygg, Peter Toftedal, Susan Nielsen, Anders Fasth, Lillemor Berntson, Ellen Nordal, Troels Herlin
OBJECTIVES: This study assessed the long-term course, remission rate and disease burden in juvenile idiopathic arthritis (JIA) 18 years after disease onset in a population-based setting from the early biologic era. METHODS: A total of 510 consecutive cases of JIA with disease onset between 1997 and 2000 from defined geographic regions in Denmark, Norway, Sweden and Finland were prospectively included in this 18-year cohort study. At the follow-up visit, patient-reported, demographic and clinical data were collected...
February 14, 2019: Arthritis Care & Research
Dax G Rumsey, Jaime Guzman, Alan M Rosenberg, Adam M Huber, Rosie Scuccimarri, Natalie J Shiff, Alessandra Bruns, Brian M Feldman, Dean T Eurich
OBJECTIVE: To estimate the impact of enthesitis on patient-reported outcomes (PROs) in children with juvenile idiopathic arthritis (JIA), irrespective of JIA category. METHODS: Children in the Research in Arthritis in Canadian Children emphasizing Outcomes (ReACCh-Out) cohort were studied. Entheseal tenderness by physician examination in 33 defined locations, Juvenile Arthritis Quality of life Questionnaire (JAQQ), Quality of My Life questionnaire (QoML), Childhood Health Assessment Questionnaire (CHAQ), and a pain visual analogue scale (VAS) were completed at enrolment, every 6 months for 2 years, and then yearly up to 5 years...
February 11, 2019: Arthritis Care & Research
Michael D George, Joshua F Baker, Kevin Winthrop, Evo Alemao, Lang Chen, Sean Connolly, Jesse Y Hsu, Teresa A Simon, Qufei Wu, Fenglong Xie, Shuo Yang, Jeffrey R Curtis
OBJECTIVES: Guidelines recommend holding biologic therapies before hip and knee arthroplasty, yet evidence to inform optimal timing is limited. We aimed to determine whether holding abatacept infusions is associated with lower risk of adverse post-operative outcomes. METHODS: This retrospective cohort study using U.S. Medicare and Truven MarketScan administrative data from 2006-September 2015 evaluated adults with RA who received intravenous abatacept (precisely dated in claims data) within 6 months of elective primary or revision hip or knee arthroplasty...
February 11, 2019: Arthritis Care & Research
Devy Zisman, Aaida Samad, Stacy P Ardoin, Peter Chira, Patience White, Idit Lavi, Emily von Scheven, Erica F Lawson, Melinda Hing, Elizabeth D Mellins
OBJECTIVE: To assess the attitudes and common practices of adult rheumatologists in the United States regarding health care transition (HCT) for young adults with rheumatic diseases. METHODS: An anonymous online survey was sent to U.S. adult rheumatologist members of the American College of Rheumatology to collect demographic data and information on attitudes and common practices regarding the transition process. RESULTS: Of 4,064 contacted rheumatologists, 203 (5%) completed the survey...
February 11, 2019: Arthritis Care & Research
Laura Kuusalo, Tuulikki Sokka-Isler, Hannu Kautiainen, Päivi Ekman, Markku J Kauppi, Laura Pirilä, Tuomas Rannio, Toini Uutela, Timo Yli-Kerttula, Kari Puolakka
OBJECTIVE: Frequent monitoring of early rheumatoid arthritis (RA) patients is required for achieving good outcomes. We studied the influence of text message (SMS) enhanced monitoring on early RA outcomes. METHODS: We randomized 166 early, disease-modifying antirheumatic drug naive RA patients to SMS-enhanced follow-up or routine care. All patients attended visits at 0, 3, and 6 months, and a follow-up visit at 12 months. Treatment was at the physicians' discretion...
February 11, 2019: Arthritis Care & Research
Julie Gandrup, Jing Li, Zara Izadi, Milena Gianfrancesco, Torkell Ellingsen, Jinoos Yazdany, Gabriela Schmajuk
OBJECTIVE: Applying treat to target strategies in the care of patients with rheumatoid arthritis (RA) is critical for improving outcomes, yet electronic health records (EHRs) have few features to facilitate this strategy. We evaluated the effect of three health-IT initiatives on performance of RA disease activity measures and outcomes in an academic rheumatology clinic. METHODS: We implemented three initiatives designed to facilitate performance of the Clinical Disease Activity Index (CDAI): an EHR flowsheet to input scores, peer performance reports, and an EHR SmartForm including a CDAI calculator...
February 11, 2019: Arthritis Care & Research
Frederick Wolfe, Juan Schmukler, Shakeel Jamal, Isabel Castrejon, Kathryn A Gibson, Sachin Srinivasan, Winfried Häuser, Theodore Pincus
OBJECTIVE: Recent studies have suggested that fibromyalgia is inaccurately diagnosed in the community, and that ~75% of persons reporting a physician diagnosis of fibromyalgia would not satisfy published criteria. To investigate possible diagnostic misclassification, we compared expert physician diagnosis with published criteria. METHODS: In a university rheumatology clinic, 497 patients completed the Multidimensional Health Assessment Questionnaire (MD-HAQ) and the 2010 American College of Rheumatology preliminary diagnostic criteria modified for self-administration during their ordinary medical visits...
February 6, 2019: Arthritis Care & Research
Don L Goldenberg
No abstract text is available yet for this article.
February 6, 2019: Arthritis Care & Research
Jessica Neely, Craig S Long, Hugh Sturrock, Susan Kim
OBJECTIVE: Ultraviolet radiation (UVR) is considered to be an important environmental factor in the clinical course of children with JDM. We aimed to evaluate the association between UVR and severe disease outcomes in JDM. METHODS: This is a cross-sectional study of JDM subjects enrolled in the U.S. multi-center Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry from 2010-15. Mean UV index (mUVI) in the calendar month prior to symptom onset in each subject's zip code was calculated from daily satellite solar noon measurements...
February 4, 2019: Arthritis Care & Research
Erika Mosor, Michaela Stoffer-Marx, Günter Steiner, Karim Raza, Rebecca J Stack, Gwenda Simons, Marie Falahee, Di Skingle, Mircia Dobrin, Georg Schett, Matthias Englbrecht, Josef S Smolen, Ingvild Kjeken, Axel J Hueber, Tanja A Stamm
OBJECTIVE: Little is known about the experiences, values and needs of people without arthritis who undergo predictive biomarker testing for the development of rheumatoid arthritis (RA). Our study aimed to explore the perspectives of these individuals and describe their information needs. METHODS: A qualitative, multicenter interview study with a thematic analysis was conducted in Austria, Germany and the UK. Individuals who underwent predictive biomarker testing for RA and had a positive test result, but no diagnosis of any inflammatory joint disease, were interviewed...
February 2, 2019: Arthritis Care & Research
Daniel S Hammenfors, Valéria Valim, Blanca E R G Bica, Sandra G Pasoto, Vibke Lilleby, Juan Carlos Nieto-González, Clovis A Silva, Esther Mossel, Rosa M R Pereira, Aline Coelho, Hendrika Bootsma, Akaluck Thatayatikom, Johan G Brun, Malin V Jonsson
BACKGROUND/OBJECTIVES: Juvenile Sjögren's syndrome (jSS) is a rare, poorly defined and possibly underdiagnosed condition affecting children/adolescents. The aim of this study was to characterize symptoms and clinical findings of jSS, and to explore the clinical application of major salivary gland ultrasonography (SGUS) in patients with jSS. METHODS: A cross-sectional multicenter study recruited patients with disease onset until 18 years of age (n=67). Disease characteristics were recorded, unstimulated whole sialometry and SGUS examination of the parotid and submandibular salivary glands was performed...
January 30, 2019: Arthritis Care & Research
Yiu-Shing Lau, Mark Harrison, Matt Sutton
BACKGROUND: Patients experience discomfort and compromised quality of life whilst waiting for hip replacement. Symptom duration may affect quality of life attained following surgery, but no population-level evidence exists on the impact of symptom duration on pre- and post-surgical outcomes. METHODS: National observational data collected before and after hip replacement surgery in England between 2009 and 2016 was used to investigate determinants of symptom duration prior to surgery, and the relationship between symptom duration and pre- and post-surgical patient-reported outcomes...
January 25, 2019: Arthritis Care & Research
Dilek Solmaz, Sibel Bakirci, Gezmis Kimyon, Esen Kasapoglu Gunal, Atalay Dogru, Ozun Bayindir, Ediz Dalkilic, Cem Ozisler, Meryem Can, Servet Akar, Gozde Yildirim Cetin, Sule Yavuz, Levent Kilic, Emine Figen Tarhan, Orhan Kucuksahin, Ahmet Omma, Emel Gonullu, Fatih Yildiz, Emine Duygu Ersozlu, Muhammet Cinar, Atallah Onazi, Muge Aydin Tufan, Abdulsamet Erden, Sema Yilmaz, Seval Pehlevan, Umut Kalyoncu, Sibel Zehra Aydin
OBJECTIVE: Psoriatic arthritis (PsA) has a genetic background. Approximately 40% of patients have a family history of psoriasis or PsA, which may affect disease features. The aim of this study was to assess the effects of family history of psoriasis and PsA on disease phenotypes. METHODS: The data from 1393 patients recruited in the longitudinal, multicenter Psoriatic Arthritis-International Database (PsArt-ID) were analyzed. The effects of family history of psoriasis and/or PsA on characteristics of psoriasis and PsA were investigated using logistic regression...
January 25, 2019: Arthritis Care & Research
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