Wouter S Hoogenboom, Todd G Rubin, Kenny Ye, Min-Hui Cui, Kelsey C Branch, Jinyuan Liu, Craig A Branch, Michael L Lipton
Mild traumatic brain injury (mTBI), also known as concussion, is a serious public health challenge. Although most patients recover, a substantial minority suffers chronic disability. The mechanisms underlying mTBI-related detrimental effects remain poorly understood. Although animal models contribute valuable preclinical information and improve our understanding of the underlying mechanisms following mTBI, only few studies have used diffusion tensor imaging (DTI) to study the evolution of axonal injury following mTBI in rodents...
2019: Journal of Experimental Neuroscience