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Cardiology Research and Practice

Guiling Ma, Xuejiao Wu, Lijun Zeng, Jiawei Jin, Xingpeng Liu, Jianjun Zhang, Lin Zhang
Objectives: To investigate the association of serum autoantibodies against M2-muscarinic acetylcholine receptor (anti-M2-R) with atrial fibrosis in long-standing persistent atrial fibrillation (AF) patients. Methods: Twenty-four long-standing persistent AF patients, scheduled to undergo hybrid ablation surgery, were enrolled in the study. Twenty-six patients with sinus rhythm, scheduled to undergo coronary artery bypass grafting surgery, were enrolled into the non-AF group...
2019: Cardiology Research and Practice
Robby Singh, Marcel Zughaib
Background: As the number of procedures using contrast media continues to rise, the ensuing complications place an ever increasing burden on the healthcare system. Contrast-induced nephropathy (CIN) is a common postprocedural complication after cardiac catheterization. Objectives: The purpose of our study was to evaluate the impact of physician behavioral modification on reducing the amount of contrast used during the procedure. Methods: All patients who underwent procedures in the cardiac catheterization laboratory from January 2013 to August 2016 were identified in addition to the total contrast used during the procedure, the type of procedure performed, and the operator performing the procedure...
2019: Cardiology Research and Practice
Florah Tshepo Moshapa, Kirsten Riches-Suman, Timothy Martin Palmer
Type 2 diabetes mellitus (T2DM) is increasing worldwide, and it is associated with increased risk of coronary artery disease (CAD). For T2DM patients, the main surgical intervention for CAD is autologous saphenous vein grafting. However, T2DM patients have increased risk of saphenous vein graft failure (SVGF). While the mechanisms underlying increased risk of vascular disease in T2DM are not fully understood, hyperglycaemia, insulin resistance, and hyperinsulinaemia have been shown to contribute to microvascular damage, whereas clinical trials have reported limited effects of intensive glycaemic control in the management of macrovascular complications...
2019: Cardiology Research and Practice
Ozlem Elkiran, Cemsit Karakurt, Gulendam Kocak, Cagatay Taskapan
Introduction: There is a concern about release of nickel and titanium after implantation of nitinol-containing devices. Objective: To evaluate serum nickel and titanium release after implantation of Amplatzer occluder. Materials and methods: In 38 pediatric patients with no history of nickel sensitivity, blood samples were drawn 24 hours before and 24 hours, 1, 3, 6, and 12 months after implantation. Nickel and titanium concentrations were measured by atomic absorption spectrophotometry...
2019: Cardiology Research and Practice
Xue-Rong Sun, Ying Tian, Ashok Shah, Xian-Dong Yin, Liang Shi, Yan-Jiang Wang, Xiao-Qing Liu, Meleze Hocini, Michel Haissaguerre, Xin-Chun Yang, Xing-Peng Liu
Background: In patients with persistent atrial fibrillation (AF), the procedural and clinical outcomes of ablation combined with infusion of antiarrhythmic drug are unknown. Objectives: To determine the impact of low-dose ibutilide after circumferential pulmonary vein isolation (CPVI) and/or left atrial (LA) substrate modification on acute procedural and clinical outcome of persistent AF. Methods: In a prospective cohort of 135 consecutive patients with persistent AF, intravenous 0...
2019: Cardiology Research and Practice
Jinlong Zhao, Feng Li, Yueli Zhang, Zhongyun Zhuang, Man Wang, Liang Fu, Yinkai Ni, Zhexin Lu, Zonghui Chen, Cheng Zhang
Aims: To investigate a new method of left atrial appendage occlusion without fluoroscopy. Methods and Results: We performed left atrial appendage occlusion for 14 patients with atrial fibrillation in our hospital. All of the surgeries were completed in a general surgery setting, avoiding fluoroscopy, and in each case, the entire procedure was guided by transesophageal echocardiography (TEE). All of the surgeries were performed through the femoral vein pathway. All operations went smoothly with no serious complications...
2019: Cardiology Research and Practice
Dou Yuan, Ping Zheng, Chen Tan, Si Hui Huang, Dan Li, Jian Huang
Background: Elucidation of mechanisms underlying continuous training-related atrial fibrillation (AF) may inform formulation of novel therapeutic approaches and training method selection. This study was aimed at assessing mechanisms underlying continuous training-induced AF in an animal model. Methods: Healthy New Zealand rabbits were divided into three groups ( n =8 each), namely, control (C), and moderate intensity (M), and high intensity (H) continuous training according to treadmill speed...
2018: Cardiology Research and Practice
Brenda Kelly Souza Silveira, Thatianne Moreira Silva Oliveira, Patrícia Amaro Andrade, Helen Hermana Miranda Hermsdorff, Carla de Oliveira Barbosa Rosa, Sylvia do Carmo Castro Franceschini
[This corrects the article DOI: 10.1155/2018/4762575.].
2018: Cardiology Research and Practice
Wei Wang, Zhaolei Jiang, Rongxin Lu, Hao Liu, Nan Ma, Jie Cai, Min Tang, Ju Mei
Introduction: Catheter-based renal denervation (RDN) could reduce cardiac sympathetic nerve activity (SNA) and inhibit atrial fibrillation (AF). However, the reliability is uncertain, because the renal sympathetic nerves are mainly distributed in the adventitial surface of the renal artery. Objective: The aims of this study were to test the hypothesis that renal artery adventitial ablation (RAAA) definitely had the effects of RDN and to study the effects of RDN via renal artery adventitial cryoablation (RAAC) on AF and cardiac neural remodeling...
2018: Cardiology Research and Practice
Jiqiang Hu, Wu Kuang, Xiaoyun Cui, Yan Li, Yang Wu, Qian Lin, Xuan Wang
Introduction: A concealed pulmonary vein (PV) bigeminy (cPVB) may be found in some patients with atrial fibrillation (AF) during sinus rhythm (SR). The aim of this study was to investigate whether the presence of cPVB during SR is associated with a higher PV firing. Methods and Results: Seven hundred seventy-six PVs (excluding 5 right middle PVs and 8 left common trunks) were mapped in 198 patients with paroxysmal AF (PAF) who underwent circumferential PV isolation...
2018: Cardiology Research and Practice
Boldizsar Kovacs, Sven Reek, Nazmi Krasniqi, Urs Eriksson, Firat Duru
Background: Wearable cardioverter-defibrillators (WCD, LifeVest, ZOLL) can protect from sudden cardiac death bridging a vulnerable period until a decision on implantable cardioverter-defibrillator (ICD) implantation can be reached. WCD is commonly used for 3 months or less. It is unknown, which patients use WCD longer and which patients are most likely to benefit from it. Hypothesis: Extended use of WCD is reasonable in selected cases based on underlying heart disease and overall patient risk profile...
2018: Cardiology Research and Practice
Nixiao Zhang, Gary Tse, Shristi Dahal, Yajuan Yang, Mengqi Gong, Calista Zhuo Yi Chan, Enzhao Liu, Gang Xu, Konstantinos P Letsas, Panagiotis Korantzopoulos, Guangping Li, Tong Liu
Background: Use of amiodarone (AMIO) in atrial fibrillation (AF) has significant side effects over prolonged periods. Wenxin Keli (WXKL), a Chinese herb extract, has been shown to be effective in atrial-selective inhibiting peak I Na and hence beneficial in treating atrial arrhythmias, including atrial fibrillation. The aim of this randomized controlled trial was to evaluate potential effects of AMIO plus WXKL on conversion rate and time in patients with recent-onset AF. Methods: A total of 41 patients (71 ± 12 years, 44% male) with recent-onset (<48 h) AF eligible for conversion were randomized to receive either intravenous amiodarone (loading dose 5 mg/kg in 1 hour followed by 50 mg/h; n =21) or amiodarone with same dosage plus oral WXKL 18 g thrice daily ( n =20) for 24 hours...
2018: Cardiology Research and Practice
Xiao-Yu Liu, Hai-Feng Shi, Jie Zheng, Ku-Lin Li, Xiao-Xi Zhao, Shi-Peng Dang, Ying Wu, Yan Cheng, Xiao-Yan Li, Zhi-Ming Yu, Ru-Xing Wang
Objective: The objective of this study was to investigate the impact of left atrial (LA) size for the ablation of atrial fibrillation (AF) using remote magnetic navigation (RMN). Methods: A total of 165 patients with AF who underwent catheter ablation using RMN were included. The patients were divided into two groups based on LA diameter. Eighty-three patients had small LA (diameter <40 mm; Group A), and 82 patients had a large LA (diameter ≥40 mm; Group B)...
2018: Cardiology Research and Practice
Brenda Kelly Souza Silveira, Juliana Farias de Novaes, Nínive de Almeida Reis, Larissa Pereira Lourenço, Ana Helena Moretto Capobiango, Sarah Aparecida Vieira, Helen Hermana Miranda Hermsdorff
This study aimed at determining the dietary patterns and investigating their association with cardiometabolic risk markers in a brazilian population at risk. This transversal study was carried out with data of 265 patients ( n = 123 M/172 W, age 42 ± 16 years) of the Cardiovascular Health Care Program-PROCARDIO-UFV, Brazil-who had their first appointment between 2012 and 2017. A 24-hour recall was applied. The dietary patterns were determined by Principal Component Analysis. Anthropometric, clinical-metabolic, sociodemographic, and lifestyle data were collected through medical record analysis...
2018: Cardiology Research and Practice
Tim Salinger, Kai Hu, Dan Liu, Scharoch Taleh, Sebastian Herrmann, Daniel Oder, Daniel Gensler, Jonas Müntze, Georg Ertl, Kristina Lorenz, Stefan Frantz, Frank Weidemann, Peter Nordbeck
Background: Fast progression of the transaortic mean gradient ( P mean ) is relevant for clinical decision making of valve replacement in patients with moderate and severe aortic stenosis (AS) patients. However, there is currently little knowledge regarding the determinants affecting progression of transvalvular gradient in AS patients. Methods: This monocentric retrospective study included consecutive patients presenting with at least two transthoracic echocardiography examinations covering a time interval of one year or more between April 2006 and February 2016 and diagnosed as moderate or severe aortic stenosis at the final echocardiographic examination...
2018: Cardiology Research and Practice
Robby Singh, Leon Varjabedian, Georgy Kaspar, Marcel Zughaib
Introduction: Congestive heart failure is a leading cause of cardiovascular morbidity and mortality that results in a significant financial burden on healthcare expenditure. Though various strategies have been employed to reduce hospital readmissions, one valuable tool that remains greatly underutilized is the CardioMEMS ( Abbott ), a remote pulmonary artery pressure-monitoring system, which has been shown to help reduce heart failure rehospitalizations in the CHAMPION (CardioMEMS Heart Sensor Allows Monitoring of Pressure to Improve Outcomes in NYHA Class III Heart Failure Patients) trial...
2018: Cardiology Research and Practice
Yu-Chuan Wang, Bo Huang, Kang Li, Peng-Kang He, Er-Dong Chen, Yu-Long Xia, Jie Jiang, Qin-Hui Sheng, Jing Zhou, Yan-Sheng Ding
Objectives: To identify optimal predefined criteria (OPC) for filters of the VisiTag™ module in the CARTO 3 system during pulmonary vein isolation (PVI). Methods: Thirty patients with atrial fibrillation (AF) who experienced PVI first were enrolled. PVI was accomplished by using a Thermocool SmartTouch catheter. Ablation lesions were tagged automatically as soon as predefined criteria of the VisiTag™ module were met. OPC should be that ablation with the setting resulting in the conduction gap (CG) as few as possible, while contiguous encircling ablation line (CEAL) without the tag gap (TG) on the 3D anatomic model as much as possible...
2018: Cardiology Research and Practice
Sandro Brusich, Ivan Zeljković, Nikola Pavlovic, Ante Anić, Zrinka Jurišić, David Židan, Marina Klasan, Zlatko Čubranić, Kenneth Dickstein, Cecilia Linde, Camilla Normand, Sime Manola
Aims: The Cardiac Resynchronization Therapy (CRT) Survey II was conducted between October 2015 and December 2016 and included data from 11088 CRT implantations from 42 countries. The survey's aim was to report on current European CRT practice. The aim of this study was to compare the Croatian national CRT practice with the European data. Methods: Five centres from Croatia recruited consecutive patients, in a 15-month period, who underwent CRT implantation, primary or an upgrade...
2018: Cardiology Research and Practice
Chi-Wei Chang, Kuo-Meng Liao, Yi-Ting Chang, Sheng-Hung Wang, Ying-Chun Chen, Gin-Chung Wang
Background: It has been reported that harmonics of radial pulse is related to coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM). It is still unclear whether or not the first harmonics of the radial pulse spectrum is an early independent predictor of silent coronary artery disease (SCAD) and adverse cardiac events (ACE). Objectives: To measure the risk of SCAD in patients with T2DM and also to survey whether or not an increment of the first harmonic ( C 1) of the radial pulse increases ACE...
2018: Cardiology Research and Practice
Christopher DeZorzi
As advances in medical technology arise and the availability of cancer treatment increases, an increased number of patients are receiving cancer treatment. Radiation therapy has evolved to become one of the cornerstones of treatment for various types of cancers. One of the long-term consequences of radiation therapy is radiation-induced coronary artery disease (RICAD). Although the pathophysiology of RICAD may be slightly different and more acute onset than the commonly seen "generic" coronary artery disease, it is common practice to treat RICAD in the same method as nonradiation-induced CAD...
2018: Cardiology Research and Practice
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