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International Journal of General Medicine

Abdullah Abdulfattah Mashat, Ahmed Hussein Subki, Moaz Abdulrahman Bakhaider, Wejdan Mohammad Baabdullah, Jawaher Badr Walid, Abdulrahman Hatim Alobudi, Maged Mazen Fakeeh, Anas Jamal Algethmi, Wesam Awad Alhejily
Introduction: Atrial fibrillation (AF) is the most common type of cardiac arrhythmia worldwide and carries significant risk of morbidity and mortality. The prevalence of AF is high in significant parts of the world, but not much is known from countries, such as Saudi Arabia. Aims: To study the risk factors, etiologies, comorbidities, and outcome of AF in Saudi Arabia. Patients and methods: A retrospective study was conducted in King Abdul-Aziz Hospital in Jeddah during the period 2010-2017...
2019: International Journal of General Medicine
Mohammed Ali Almalki, Maram Nader AlJishi, Maie Abdulrhman Khayat, Hotoun Fayez Bokhari, Ahmed Hussein Subki, Abdulrahman Mousa Alzahrani, Wesam Awad Alhejily
Background: Coronary artery disease (CAD) is a serious cardiovascular disorder affecting middle-aged individuals. It is a major cause of death among adults over the age of 35 years. In Saudi Arabia, CAD is associated with higher mortality rate, and Saudi patients are reported to have significantly higher prevalence of risk factors for CAD than the Western population. Furthermore, as, to date, there is no definite cure for CAD, prevention of the disease and tight control of the known risk factors are the cornerstones for reducing CAD-associated mortality...
2019: International Journal of General Medicine
Ahmed Hussein Subki, Mahmoud Ghaleb Bakhaidar, Moaz Abdulrahman Bakhaider, Ali Abdulrahman Alkhowaiter, Rakan Salah Al-Harbi, Mohammed Ali Almalki, Khalid Abdullah Alzahrani, Maged Mazen Fakeeh, Siham Hussein Subki, Wesam Awad Alhejily
Background: Mitral valve prolapse (MVP) is the most common cardiac valvular abnormality in developed countries and it is associated with considerable morbidity and mortality. Aim of work: To study the clinical presentations, risk factors, and echocardiographic features of patients with MVP in Jeddah, Saudi Arabia. Materials and methods: A retrospective chart review study was conducted in King Abdulaziz teaching hospital in Jeddah, Saudi Arabia, from 2007 to 2017...
2019: International Journal of General Medicine
Abdulrahman Ibrahim Mufti Alsadiqi, Ahmed Hussein Subki, Rami Hussam Abushanab, Mohammed Rashid Ocheltree, Hattan Ahmed Bajahmom, Yosef Ibrahim Mufti Alsadiqi, Wesam Awad Alhejily
Background: Peripheral artery disease (PAD) is a major health problem in Saudi Arabia with considerable implications for morbidity and mortality. Many risk factors have been established for developing PAD, but the prevalence of these risk factors is variable from one country to another. Aim: To identify the risk factors for PAD and study their prevalence in Jeddah, Saudi Arabia. Methods: A retrospective chart review study was conducted in a tertiary center in Jeddah from July 2012 to September 2015...
2019: International Journal of General Medicine
Maenia Scarpino, Giovanni Lanzo, Francesco Lolli, Antonello Grippo
Cerebral fat embolism (CFE) is an uncommon incomplete type of fat embolism syndrome (FES), characterized by purely cerebral involvement. It usually occurs 12-72 hours after the initial trigger, mainly represented by closed, long-bone multiple fractures of the lower extremities. Neurological manifestations are mainly characterized by headache, confusion, seizures, focal deficit, and alteration of the consciousness state up to coma onset. It represents a diagnostic challenge, above all when secondary to uncommon nontraumatic causes, because neurological signs and symptoms are variable and nonspecific, not satisfying the Gurd and Wilson's criteria, the diagnostic features most widely used today for FES diagnosis...
2019: International Journal of General Medicine
Mira Adhikari Baral
Purpose: Dry powder inhalation is a cornerstone of treatment in patients with COPD. This study was undertaken to study the knowledge and practice of dry powder inhalation among such patients. Patients and methods: The current study was a cross-sectional study conducted in Western Regional Hospital, Pokhara, Nepal. The study was conducted among 204 COPD patients (outpatients and inpatients) aged ≥20 years who had been using rotahaler, a dry powder inhaler device, and a purposive sampling technique was used...
2019: International Journal of General Medicine
Manar Al-Lawama, Haitham Alkhatib, Zaid Wakileh, Randa Elqaisi, Ghada AlMassad, Eman Badran, Tyler Hartman
Purpose: Bubble continuous positive airway pressure (bCPAP), a noninvasive respiratory support modality used to manage newborns with respiratory distress, provides continuous pressure that helps prevent derecruitment of alveoli, increasing the lungs' functional residual capacity, and thus decreasing the work of breathing. bCPAP can be used to manage various respiratory conditions in the newborn. In this prospective study, we describe our experience using bCPAP therapy as the primary respiratory support in a level III neonatal unit in Amman, Jordan...
2019: International Journal of General Medicine
Munirah Alsaleh, Zoe Leftley, Thomas A Barbera, Paiboon Sithithaworn, Narong Khuntikeo, Watcharin Loilome, Puangrat Yongvanit, I Jane Cox, Nittaya Chamodol, Richard Ra Syms, Ross H Andrews, Simon D Taylor-Robinson
Cholangiocarcinoma (CCA) is a tumor with increasing prevalence around the world. The prevalence of CCA is highest in East Asia and most significantly in the countries through which the Mekong River flows, owing to the presence of liver flukes, which are consumed in raw fish dishes. Outside Asia, the causes of bile duct cancers for the most part are unknown. In this review, we assess the current state of knowledge in both fluke-associated and sporadic CCA, from etiological, diagnostic, and treatment perspectives...
2019: International Journal of General Medicine
A Mohammadpour, H Keshavarz, M Mohebali, M Salimi, A Teimouri, S Shojaee
Background: Toxoplasma gondii is an intracellular protozoan parasite distributed worldwide. Although the infection is benign in immunocompetent individuals, it is life threatening and complicated in immunocompromised patients and fetuses of pregnant women who received their first exposure to T. gondii during the pregnancy. Prolactin (PRL) is a hormone that is secreted by the pituitary gland, and it is confirmed that it plays a role in the immune system. The present study was carried out to assess the possible relation between serum PRL levels and Toxoplasma infection frequency in human...
2019: International Journal of General Medicine
Ra Tuty Kuswardhani, Ketut Gede Wiradharma, Yenny Kandarini, Gde Raka Widiana, Elysanti Dwi Martadiani
Purpose: The aim of this study was to analyze the association of the carotid intima-media thickness (CIMT) with various parameters in patients on maintenance hemodialysis (mHD). Methods: A cross-sectional study was conducted, enrolling 68 subjects (41 men, 27 women) on mHD in the Hemodialysis Unit, Sanglah Hospital, Denpasar, Indonesia. CIMT was measured with B-mode ultrasonography using a USG Sonoace 8000 and a 7.5 MHz linear transducer. Results: CIMT was higher in subjects with cardiovascular disease (CVD) compared with those without CVD (0...
2019: International Journal of General Medicine
Henry Wamala, Leena Aggarwal, Anne Bernard, Ian A Scott
Introduction: We compared performance of nine risk scores for coronary heart disease (CHD) among patients presenting to an emergency department (ED) with undifferentiated chest pain of possible coronary origin. Methods: A retrospective study was undertaken of adult patients presenting with chest pain to atertiary hospital ED with no electrocardiographs or troponin results diagnostic of ischemic chest pain (ICP) or acute coronary syndrome at ED presentation, and no clearly evident noncoronary diagnosis...
2018: International Journal of General Medicine
Marwan A Albeshri, Mohammed S Alsallum, Sulafa Sindi, Mohammed Kadi, Abdullah Albishri, Hanadi Alhozali, Kamal Alghalayini
Introduction: Left ventricular dysfunction (LVD) is characterized as left ventricular ejection fraction (EF) below half of the systolic capacity of the left ventricle. Patients on hemodialysis have higher risk of developing LVD than the general population. Our aim was to assess hospitalization rate and outcomes in hemodialysis patients with LVD. Patients and methods: All patients ≥18 years old, who started hemodialysis therapy at King Abdulaziz University Hospital between January 2011 and December 2011, were identified using medical records of hemodialysis unit...
2018: International Journal of General Medicine
Anas Awad Alsolami, Khalid Z Alshali, Marwan Ahmad Albeshri, Shikih Hussain Alhassan, Abdalrhman Mohammed Qazli, Ahmed Saad Almalki, Marwan A Bakarman, Abdel Moniem Mukhtar
Objectives: Type 2 diabetes mellitus (DM-II) is highly prevalent in Saudi Arabia and only few studies have assessed it as a risk factor for hypothyroidism. This study aimed to examine the association between DM-II and hypothyroidism. Subjects and methods: We conducted a hospital-based case-control study. As cases, we included all adults admitted to King Abdulaziz University Hospital (KAUH) with laboratory-confirmed hypothyroidism. As controls, we drew a random sample of patients admitted to the orthopedic clinic at KAUH with laboratory-confirmed absence of hypothyroidism...
2018: International Journal of General Medicine
Derek Matthews, Robert Atkinson, Adrian Shephard
Purpose: Pharyngitis is commonly caused by a self-limiting upper respiratory tract infection (URTI) and symptoms typically include sore throat. Antibiotics are often inappropriately used for the treatment of pharyngitis, which can contribute to antimicrobial resistance, therefore non-antibiotic treatments which have broad antiseptic effects may be more appropriate. Amylmetacresol (AMC) and 2,4-dichlorobenzyl alcohol (DCBA) are present in some antiseptic lozenges and have established benefits in providing symptomatic relief and some in vitro antiviral action...
2018: International Journal of General Medicine
Dahan da Cunha Nascimento, Samuel da Cunha Oliveira, Denis Cesar Leite Vieira, Silvana Schwerz Funghetto, Alessandro Oliveira Silva, Renato Valduga, Brad Jon Schoenfeld, Jonato Prestes
Objective: The objective of this study was to apply the newly standardized definition for sarcopenia from the Foundation for the National Institutes of Health (FNIH) and the current definition for obesity to 1) determine the prevalence of sarcopenic obesity (SO) in obese elderly women; 2) compare the muscle strength, lean body mass, and markers of inflammation between obese elderly women with SO and nonsarcopenic obesity (NSO), and 3) elucidate the relationship between appendicular lean mass adjusted for body mass index (aLM/BMI) with muscle strength, lean body mass, and obesity indices...
2018: International Journal of General Medicine
Ryan Choudhury
Hypoxia causes a cascade of activity from the level of the individual down to the regulation and function of the cell nucleus. Prolonged periods of low oxygen tension are a core feature of several disease states. Advances in the study of molecular biology have begun to bridge the gap between the cellular response to hypoxia and physiology. Hyperbaric oxygen therapy is a treatment for hypoxic- and inflammatory-driven conditions, in which patients are treated with 100% oxygen at pressures greater than atmospheric pressure...
2018: International Journal of General Medicine
Amal R Hubail, Roza K Belkharoeva, Natalya P Tepluk, Olga V Grabovskaya
Purpose: The aim of this study was to evaluate the progression of a case of a patient with epidermolysis bullosa (EB) since early age who survived to adulthood, presenting with recurrent skin blisters and disfiguring scars and disabling musculoskeletal deformities. Background: EB is a rare group of inherited diseases that affect the skin fragility causing it to blister in response to even minor trauma. Established novel treatments are limited in the literature due to its rarity, and more research is needed to set a global management approach...
2018: International Journal of General Medicine
Thang Thanh Phan, Toan Trong Ho, Hue Thi Nguyen, Hang Thuy Nguyen, Thu Bich Tran, Son Truong Nguyen
Purpose: To identify and clarify the roles of inflammatory markers in prognosis for advanced non-small cell lung cancer (NSCLC) patients treated with EGFR tyrosine kinase inhibitor (TKI). Patients and methods: One hundred and twelve adenocarcinoma, clinical stage IV, NSCLC patients with either EGFR exon 19 deletion (E19del) or EGFR exon 21 L858R substitution mutation (L858R) were selected for this study. The blood cell count at different stages of treatment was used to calculate the inflammatory markers...
2018: International Journal of General Medicine
Shunsuke Kojima, Eiji Hiraoka, Junya Arai, Yosuke Homma, Yasuhiro Norisue, Osamu Takahashi, Taihei Soma, Toshihiko Suzuki, Masahiko Noguchi, Kentaro Shibayama, Kotaro Obunai, Hiroyuki Watanabe
Background: A do-not-resuscitate (DNR) order is reportedly associated with a decrease in performance measures, but it should not be applied to noncardiopulmonary resuscitation procedures. Good performance measures are associated with improvement in heart failure outcomes. Aim: To analyze the influence of DNR order on performance measures of heart failure at our hospital, where lectures on DNR order are held every 3 months. Design: Retrospective cohort study...
2018: International Journal of General Medicine
Christoforos Kosmidis, Nikolaos Varsamis, Georgios Anthimidis, Sofia Baka, Dimitrios Valoukas, Triantafyllia Koletsa, Katerina Zarampouka, Georgios Koimtzis, Eleni Georgakoudi, Paul Zarogoulidis, Christoforos Efthymiadis
Introduction: Breast cancer is the most common malignancy in women worldwide. Long-term survivors among patients treated for breast cancer are at a high risk for developing a second primary malignancy. Hepatocellular carcinoma is the most frequent primary hepatic malignancy and should be ruled out in breast cancer patients who are diagnosed with solitary hepatic lesions. False diagnosis may lead to inappropriate oncologic staging and treatment of the disease. Case presentation: We present the case of a 73-year-old female patient who had been treated for invasive ductal breast cancer 7 years ago and was diagnosed with a solid hepatic lesion at segments VI and VII and a small, calcified lesion at the tail of the pancreas on follow-up with an abdominal computed tomography...
2018: International Journal of General Medicine
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