journal
Journals International Journal of Gener...

International Journal of General Medicine

https://read.qxmd.com/read/38601196/microbial-disruptions-in-inflammatory-bowel-disease-a-comparative-analysis
#1
JOURNAL ARTICLE
Jianxia Ma, Ke Wang, Jun Wang, Qinlian Zeng, Kangwei Liu, Songbai Zheng, Yuanwen Chen, Jianfeng Yao
OBJECTIVE: The fecal microbiota was studied in patients with inflammatory bowel disease (IBD), and the characteristics of gut microbiota were compared among patients with different subtypes and stages of IBD, aiming to identify the gut microbiota associated with IBD. METHODS: Fecal samples were collected from 41 IBD patients (18 patients with ulcerative colitis [UC] and 23 patients with Crohn's disease [CD]) in the Department of Gastroenterology of East China Hospital, Fudan University between January 2021 and January 2022...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38601195/predictors-and-clinical-significance-of-myocardial-injury-in-elderly-patients-under-the-covid-19-pandemic
#2
JOURNAL ARTICLE
You Zhou, Jing Dong, Hao Lu
BACKGROUND: The elderly patients are at increased high risk of myocardial injury and mortality after the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aims to investigate the prevalence, predictors and prognostic implications of myocardial injury in the elderly patients with SARS-CoV-2 infection. METHODS: Patients aged over 65 years were consecutively recruited between April to May, 2022. Myocardial injury was assessed using the high-sensitivity cardiac troponin T (hs-cTnT) assay...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38596647/correlation-between-maternal-anxiety-during-mid-pregnancy-and-subsequent-infant-sleep-issues-letter
#3
JOURNAL ARTICLE
Azniah Syam, Hasta Handayani Idrus, Imelda Iskandar
No abstract text is available yet for this article.
2024: International Journal of General Medicine
https://read.qxmd.com/read/38596646/formula-feeding-practice-and-associated-factors-among-mothers-who-visited-health-facilities-for-their-infants-aged-below-6-months-in-bahir-dar-city-northwest-ethiopia-2020-letter
#4
JOURNAL ARTICLE
https://read.qxmd.com/read/38596645/laying-the-groundwork-a-pilot-study-exploring-improved-endometriosis-management-strategies-in-primary-healthcare
#5
JOURNAL ARTICLE
Maria Öberg Westin, Carl Wikberg, Cecilia Björkelund, Nashmil Ariai, Ann-Christine Lindahl, Dominique Hange
OBJECTIVE: To evaluate if a brief educational intervention for primary health care staff regarding endometriosis gives sustainable knowledge of endometriosis symptoms and if a brief questionnaire for women seeking care for common symptoms is feasible in the Swedish primary care context. DESIGN: Pilot study. SETTING: 3 primary care centres (PCCs) in Sweden. Exploring knowledge among staff about endometriosis at baseline and 3 months after an information workshop...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38596644/the-use-of-muscle-relaxants-after-chemotherapy-and-radiotherapy
#6
REVIEW
Paweł Radkowski, Michał Jacewicz, Iwona Podlińska, Maria Derkaczew
INTRODUCTION: Patients after chemotherapy and radiotherapy while being operated can suffer from different systemic problems, which may complicate the anesthetic management. Some interactions between muscle relaxants and chemotherapeutics can occur. AIM: This article aims to present the use of muscle relaxants in cancer patients who have undergone chemotherapy and radiotherapy. MATERIAL AND METHODS: Our work is based on the available literature and the authors' experience...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38596643/prevalence-and-patterns-of-congenital-heart-defects-and-other-major-non-syndromic-congenital-anomalies-among-down-syndrome-patients-a-retrospective-study
#7
JOURNAL ARTICLE
Biniam Endale Geleta, Girma Seyoum
BACKGROUND: Children with DS are at higher risk of developing congenital anomalies, particularly cardiac anomalies. METHODS: Medical records of 502 DS patients were reviewed. The logistic regression analyses were performed to determine independent predictors. RESULTS: Of the total 502 study subjects, 53.4% were males. Only 1.4% of the DS case diagnosis were confirmed by karyotyping. All cases were diagnosed postnatally. The median age at DS diagnosis was 5 months...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38591000/lack-of-physician-dentist-collaboration-in-aspiration-pneumonia-prevention
#8
JOURNAL ARTICLE
Taiju Miyagami, Satoshi Teranaka, Yuichiro Mine, Tomohiro Matsumoto, Yuki Yoshimatsu, Shinichi Matsumoto, Kohei Yamaguchi, Toru Morikawa
This opinion paper addresses the challenges and future directions for preventing aspiration pneumonia in Japan's rapidly aging population. It highlights the increasing proportion of elderly individuals and the associated rise in health issues like decreased swallowing function, a risk factor for aspiration pneumonia. The paper emphasizes the effectiveness of dentist-provided oral care in preventing this condition but notes the lack of collaboration between dentists and physicians in Japan's clinical practice...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38590999/he4-serum-levels-are-associated-with-poor-prognosis-in-patients-with-acute-heart-failure-combined-with-chronic-kidney-disease
#9
JOURNAL ARTICLE
Yi Tang, Zhengqi Hu, Zhibin Liu, Siling Peng, Tiancheng Liu, Yaoyuan Xiao, Jianqiang Peng, Hongwei Pan, Zhaofen Zheng, Jin He
PURPOSE: The levels of human epididymis protein 4 (HE4) is associated not only with the prognosis of patients with acute heart failure (AHF), but also with chronic kidney disease (CKD). Our study aims to understand the prediction value of HE4 on prognosis in patients with AHF combined with CKD. PATIENTS AND METHODS: This study prospectively enrolled patients diagnosed with AHF combined with CKD at the Department of Cardiology of Hunan Provincial People's Hospital from March 2019 to December 2022...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38590998/the-prevalence-and-risk-factors-of-trichosporonosis-at-king-abdulaziz-university-hospital
#10
JOURNAL ARTICLE
Ghassan J Alboloshi, Asif A Jiman-Fatani, Dalya Attallah, Jawahir A Mokhtar, Nabeela Abdullah Al-Abdullah, Khalil Alkuwaity, Reham Kaki, Mohammed W Al-Rabia, Abdelbagi Alfadil, Karem Ibrahem, Addisu D Teklemariam, Steve Harakeh
BACKGROUND: Fungal infections, especially those caused have emerged as a significant medical concern over the past three decades, particularly among immunocompromised patients. However, recent studies have highlighted the increasing prevalence of fungal infections resembling yeast other than Candida , such as trichosporonosis, especially among immunosuppressed individuals worldwide. Trichosporon has been identified as a significant contributor to superficial and invasive infections. Invasive trichosporonosis, primarily affecting immunocompromised patients, poses a significant threat with high mortality rates...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38586577/awareness-attitude-and-fertility-desire-in-elective-oocyte-cryopreservation-of-adults-in-four-areas-of-china
#11
JOURNAL ARTICLE
Yijing Xie, Chenge Liao, Xiaomei Zhai
PURPOSE: Controversy exists on whether or not elective oocyte cryopreservation (eOC) can be conducted in public hospitals in China. Policymakers should take into account the benefits and risks in the Chinese population. This study explored basic data concerning the awareness, attitudes of eOC, and fertility desire of eOC in China to offer evidence for policy making. METHODS: A total of 442 people in four areas of China responded to a survey. The questionnaire was divided into three parts: awareness, attitude, and fertility desire of eOC...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38586576/association-between-family-history-in-patients-with-primary-gout-and-left-ventricular-diastolic-function-a-cross-sectional-study
#12
JOURNAL ARTICLE
Wen Wen, Ping Lei, Wantai Dang, Liwen Ma, Jing Hu, Jian Liu
OBJECTIVE: This study aimed to employ echocardiography for measuring the markers of left ventricular (LV) diastolic function to investigate the effects of family history of gout on the LV diastolic function in patients with primary gout. METHODS: Two hundred and eighty-four patients with primary gout who visited the Department of Rheumatology and Immunology of the First Affiliated Hospital of Chengdu Medical College from September 2020 to July 2022 were selected and their family history of gout, general information, and laboratory markers were recorded...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38577398/diagnostic-value-of-carotid-plaque-assessment-with-ais-based-on-quantitative-parameters-of-dual-layer-detector-spectral-ct
#13
JOURNAL ARTICLE
Xiaoying Meng, Fei Li, Wenpei Wu, Juncang Wu
PURPOSE: To investigate the quantitative assessment of carotid plaque by each parameter of dual-layer detector spectral CT and its diagnostic value in patients with acute cerebral infarction. PATIENTS AND METHODS: Eighty-three patients with carotid atherosclerotic plaques who underwent spectral CT scanning were retrospectively included. Forty-two patients with acute ischaemic stroke (AIS) were included in the study group, and 41 patients without AIS were included in the control group...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38566832/the-effects-of-budesonide-inhalation-treatment-on-the-expression-levels-of-serum-il-6-tgf-%C3%AE-1-and-ige-and-pulmonary-function-in-patients-with-cough-variant-asthma-and-an-evaluation-of-treatment-efficacy
#14
JOURNAL ARTICLE
Yueying Niu, Mengqing Cao, Shumin Li, Juanfen Mo, Ziyi Zhu, Haiqin Wang
OBJECTIVE: To retrospectively study the effects of budesonide inhalation combined with conventional symptomatic treatment on serum inflammatory factor expression levels and pulmonary function in patients with cough variant asthma (CVA) and to evaluate treatment efficacy. METHODS: This retrospective cohort study included 200 patients diagnosed with CVA at the Second Hospital of Jiaxing between January 2022 and June 2023 and given conventional symptomatic treatment plus budesonide inhalation were included in this study...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38562211/the-association-between-epidermal-growth-factor-rs3756261-a-g-gene-polymorphism-and-the-risk-of-ankylosing-spondylitis-in-a-chinese-han-population
#15
JOURNAL ARTICLE
Hui Zhang, Wei Jiang
BACKGROUND: Epidermal growth factor (EGF) is a potent pro-angiogenic molecule promoting the angiogenic phenotype of ankylosing spondylitis (AS). Studies demonstrated that EGF rs3756261 polymorphism was associated with the risk of inflammatory diseases, but not including AS. METHODS: To investigate the association between EGF rs3756261 polymorphism and the risk of AS, we genotyped the EGF rs3756261 polymorphism in 208 patients with AS and 412 controls in a Chinese Han population using a custom-by-design 48-Plex SNP scanTM Kit...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38562210/the-potential-of-foxp3-in-predicting-survival-and-treatment-response-in-breast-cancer
#16
JOURNAL ARTICLE
Luyao Liu, Wang Xiao, Chaojie Zhang, Peizhi Fan, Jie Zeng, Jianing Yi
BACKGROUND: Breast cancer (BC) continues to pose a substantial challenge to global health, necessitating an enhanced understanding of its fundamental mechanisms. Among its various pathological classifications, breast invasive carcinoma (BRCA) is the most prevalent. The role of the transcription factor forkhead box P3 ( FOXP3 ), associated with regulatory T cells, in BRCA's diagnosis and prognosis remains insufficiently explored, despite its recognized importance. METHODS: We examined the mRNA expression profile of FOXP3 in BRCA patients, assessing its correlation with disease detection, patient survival, immune checkpoint alterations, and response to anticancer drugs...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38562209/correlations-of-aflatoxin-exposure-from-cooking-oil-and-dietary-foods-during-pregnancy-with-birth-weight-and-gestational-age-at-birth-in-guangxi-china
#17
JOURNAL ARTICLE
Yanxu Zhong, Huan Lu, Xiaodan Lu, Zhini He, Yuyan Jiang, Jie Chen, Tippawan Liabsuetrakul
BACKGROUND: Cooking oil and dietary foods are easily contaminated by aflatoxins (AFs) in Guangxi, China where low birth weight and preterm birth were prevalent. However, there are no data on AF exposure in pregnant women or their impact on newborn birth outcomes. This study aims to measure the levels and correlations of AFs in cooking oil, estimated dietary intake (EDI) of AFs in dietary foods, and serum AFB1 albumin adducts (AFB1-alb) with newborn birthweight and gestational age at birth...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38562208/associations-between-abo-blood-groups-and-diseases-in-the-digestive-system-and-vein
#18
JOURNAL ARTICLE
Feiyu Jiang, Zhiwei Liu, Ying Zhang, Tiejun Song
PURPOSE: The ABO blood type system is crucial for human blood transfusions. However, the relationships between ABO blood groups and diseases in the digestive system and vein have not been elucidated. We investigated the relationships between ABO blood groups and diseases in the digestive system and vein in this study. PATIENTS AND METHODS: A retrospective study on a Chinese population, including 1432 Crohn's disease (CD), 416 ulcerative colitis (UC), 1140 stomach cancer (SC), 841 colorectal cancer (CRC), 384 pancreatic cancer (PC), 520 liver cancer (LC), and 563 venous thrombosis (VT) patients, was performed...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38559594/the-administration-of-lemborexant-at-admission-is-not-associated-with-inpatient-falls-a-multicenter-retrospective-observational-study
#19
JOURNAL ARTICLE
Risa Hirata, Naoko E Katsuki, Hitomi Shimada, Eiji Nakatani, Kiyoshi Shikino, Chihiro Saito, Kaori Amari, Yoshimasa Oda, Midori Tokushima, Masaki Tago
PURPOSE: There has been no large-scale investigation into the association between the use of lemborexant, suvorexant, and ramelteon and falls in a large population. This study, serving as a pilot investigation, was aimed at examining the relationship between inpatient falls and various prescribed hypnotic medications at admission. PATIENTS AND METHODS: This study was a sub-analysis of a multicenter retrospective observational study conducted over a period of 3 years...
2024: International Journal of General Medicine
https://read.qxmd.com/read/38559593/involvement-of-the-abcb1-c3435t-variant-but-not-the-mthfr-c677t-or-mthfr-a1298c-variant-in-high-dose-methotrexate-induced-toxicity-in-pediatric-acute-lymphoblastic-leukemia-patients-in-china
#20
JOURNAL ARTICLE
Qie Guo, Jia-Lin Sun, Ran Li, Xiao Li
PURPOSE: It remains unclear whether the MTHFR C677T, MTHFR A1298C and ABCB1 C3435T genetic variants are associated with methotrexate (MTX) elimination delay and high-dose MTX (HD-MTX) toxicities in the treatment of pediatric acute lymphoblastic leukemia (ALL). The aim of our study was to analyze the potential predictive role of MTHFR C677T, MTHFR A1298C and ABCB1 C3435T in toxicities and the relationship between these variants and MTX elimination delay during HD-MTX therapy in pediatric ALL patients...
2024: International Journal of General Medicine
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