journal
https://read.qxmd.com/read/37775837/correction-clinical-indicators-that-influence-a-clinician-s-decision-to-start-l-thyroxine-treatment-in-prematurity-with-transient-hypothyroxinemia
#1
Aslan Yilmaz, Yavuz Ozer, Nesrin Kaya, Aydilek Dagdeviren Cakir, Hazal Cansu Culpan, Yildiz Perk, Mehmet Vural, Olcay Evliyaoglu
No abstract text is available yet for this article.
September 29, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37775784/leading-reasons-for-antibiotic-prescriptions-in-pediatric-respiratory-infections-influence-of-fever-in-a-primary-care-setting
#2
JOURNAL ARTICLE
Marina Picca, Romeo Carrozzo, Gregorio Paolo Milani, Antonio Corsello, Marina Macchi, Roberto Buzzetti, Paola Marchisio, Chiara Mameli
BACKGROUND: Antibiotic overuse in children is a significant public health concern, as it can lead to the emergence and spread of antibiotic-resistant bacteria. Although respiratory infections account for most antibiotic prescriptions in children, many of these infections are viral and do not require antibiotics. In this study, we aimed to investigate the use of antibiotics in children with respiratory infections in a primary care setting and to explore the possible role of fever on antibiotic prescription...
September 29, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37775763/neck-stiffness-and-bone-osteolytic-lesion-in-a-3-years-old-child-a-case-report
#3
JOURNAL ARTICLE
Carolina Carraro, Marco Rabusin, Flora Maria Murru, Lydie Ammar, Egidio Barbi, Alessandro Amaddeo, Giorgio Cozzi
BACKGROUND: Neuroblastoma is the most frequent extracranial solid tumor occurring in childhood, representing approximately 28% of all cancers diagnosed in infants. Signs and symptoms of neuroblastoma vary with the site of development of the tumor and can mimic other diseases due to its extreme clinical variability. However, torticollis is not reported in the medical literature as a leading symptom of neuroblastoma. CASE PRESENTATION: Here we report the case of a 3 years-old girl with fever and neck stiffness...
September 29, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37773131/when-two-z-scores-meet-analysis-of-exercise-capacity-of-children-and-adolescents-with-kawasaki-disease-by-a-new-z-score-model-of-coronary-artery-and-a-new-z-score-evaluating-peak-oxygen-consumption-coronary-artery-z-score-and-peakvo2-z-score-in-kd
#4
JOURNAL ARTICLE
Sheng-Hui Tuan, Jin-Hui Chung, Guan-Bo Chen, Shu-Fen Sun, I-Hsiu Liou, Chien-Hui Li, Yi-Ju Tsai
BACKGROUND: Coronary artery (CA) Z-score system is widely used to define CA aneurysm (CAA). Children and adolescents after acute stage of Kawasaki disease (KD-CA) have a higher risk of developing CAAs if their CA Z-score ≥ 2.5. Z-score system of peak oxygen consumption (Peak VO2 Z-score) allows comparisons across ages and sex, regardless of body size and puberty. We aimed to compare the exercise capacity (EC) indicated by peak VO2 Z-score during cardiopulmonary exercise testing (CPET) directly between KD-CA with different CA Z-score...
September 29, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37770981/year-2022-exploring-covid-19-pandemic-in%C3%A2-children
#5
REVIEW
Elena Bozzola, Carlo Caffarelli, Francesca Santamaria, Giovanni Corsello
COVID-19 pandemics is rapidly changing. In this article, we review progresses published in the Italian Journal of Pediatrics in 2022. More data on clinical pictures, prevention strategies and active management in children have been provided. The continued evolution of knowledge has driven transformations in the clinical approach to the disease and allowed key advancements in the care of children with COVID-19.
September 29, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37749617/predictors-and-a-novel-predictive-model-for-intravascular-immunoglobulin-resistance-in-kawasaki-disease
#6
JOURNAL ARTICLE
Junjie Wang, Xiaohui Huang, Donghao Guo
BACKGROUND: Early identification of intravenous immunoglobulin (IVIG) resistance contributes to better management of Kawasaki disease (KD). This study aims to establish an effective prediction model for IVIG resistance in the Chinese population. METHODS: A total of 658 eligible patients diagnosed with KD were enrolled in this study, with 461 in the training cohort and 197 in the validation cohort. The demographic characteristics and potential risk factors were compared between IVIG-responsive and resistant groups...
September 25, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37749604/beckwith-wiedemann-syndrome-and-twinning-case-report-and-brief-review-of-literature
#7
REVIEW
Pierandrea Elefante, Beatrice Spedicati, Flavio Faletra, Laura Pignata, Flavia Cerrato, Andrea Riccio, Egidio Barbi, Luigi Memo, Laura Travan
BACKGROUND: Beckwith-Wiedemann syndrome (BWS, OMIM #130,650) is a pediatric overgrowth disorder involving a predisposition to tumor development. Although the clinical management of affected patients is well established, it is less clear how to handle with the cases of siblings of affected patients, since the prevalence of the condition in twins (1:1000) is ten times higher than in singletones (1:10000). CASE PRESENTATION: We report the case of a premature twin patient who during her follow-up develops a clinical phenotype compatible with BWS, genetically confirmed in blood...
September 25, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37740208/predictive-value-of-chemokines-ccl-2-in-bronchoalveolar-lavage-fluid-for-refractory-mycoplasma-pneumonia-in-children
#8
JOURNAL ARTICLE
Jiangwei Zhu, Xue Liu, Xiaowen Zhan, Mengzhu Wang, Yuling Zhang, Li Na, Shujun Li
BACKGROUND: There are relatively few studies investigating C-C motif chemokine ligand 2 (CCL2) level in bronchoalveolar lavage fluid (BALF) in children with Mycoplasma pneumoniae pneumonia (MPP), and the relationship between CCL2 level in BALF and refractory mycoplasma pneumoniae pneumonia (RMPP) is unclear. This study aims to explore the relationship between chemokine CCL2 level in BALF and clinical characteristics and clinical outcome in children with MPP. METHODS: A total of 51 children with confirmed acute MPP and requiring bronchoalveolar lavage in Department of Pediatrics, Huanghe Sanmenxia Hospital and The First Clinical College of Xinxiang Medical University from October 2021 to February 2023 were selected as the study group...
September 23, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37726782/report-and-follow-up-on-two-new-patients-with-congenital-mesoblastic-nephroma
#9
JOURNAL ARTICLE
Gregorio Serra, Marcello Cimador, Mario Giuffrè, Vincenzo Insinga, Claudio Montante, Marco Pensabene, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz, Giovanni Corsello
BACKGROUND: Tumors are rare in neonatal age. Congenital mesoblastic nephroma (CMN) is a usually benign renal tumor observed at birth, or in the first months of life. It may also be identified prenatally and associated with polyhydramnios leading to preterm delivery. Effective treatment is surgical in most cases, consisting in total nephrectomy. In literature, very few studies report on the neonatal management of such a rare disease, and even less are those describing its uncommon complications...
September 19, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37726761/bronchiolitis-guidelines-what-about-the-italian-situation-in-a-primary-care-setting
#10
REVIEW
Federica Porcaro, Renato Cutrera, Anna Chiara Vittucci, Alberto Villani
Acute viral bronchiolitis is the most common cause of hospitalization in children under 12 months of age. The variable clinical presentation and the potential for sudden deterioration of the clinical conditions require a close monitoring by healthcare professionals.In Italy, first access care for children is provided by primary care physicians (PCPs) who often must face to a heterogeneous disease presentation that, in some cases, make the management of patient with bronchiolitis challenging. Consequently, Italian studies report poor adherence to national and international guidelines processed to guide the clinicians in decision making in acute viral bronchiolitis...
September 19, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37710275/sudden-onset-headaches-in-paediatric-emergency-departments-diagnosis-and-management
#11
REVIEW
Léa Lenglart, Cécile Monteil, Eugenia Spreafico, Thomas Moulding, Luigi Titomanlio
Headache is one of the most common pain syndromes in the paediatric population. Headaches are classified as primary (migraine, tension-type headaches, trigeminal autonomic cephalalgia and other primary headaches) or secondary (e.g. post-traumatic). Non-febrile, non-traumatic headaches represent 1% of all paediatric emergency departments (PED) visits. Many patients present with an acute, moderate to severe pain, sometimes with a sudden onset. Sudden onset headache can be the main symptom of life-threatening neurological conditions as well as a sign of primary headaches such as thunderclap or stabbing headaches...
September 14, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37705106/reduction-in-the-duration-of-postoperative-fever-following-nuss-surgery-during-the-covid-19-pandemic
#12
JOURNAL ARTICLE
An Jia, Wang Qiang, Deqin Zhuoga, Yu Di, Yang Zhaocong, Mo Xuming
BACKGROUND: Our study aimed to compare the prevalence of postoperative fever during the COVID-19 pandemic period with that of the preceding non-pandemic period. METHODS: A retrospective analysis was conducted on patients with pectus excavatum (PE) undergoing minimally invasive repair (also called NUSS procedure) at Nanjing Children's Hospital from January 1, 2017 to March 1, 2019 (Group 2019), and from January 1, 2020 to March 1, 2021 (Group 2021). Data from a total of 284 patients, consisting of 200 (70...
September 13, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37705091/peripheral-blood-micror-146a-and-micror-29c-expression-in-children-with-mycoplasma-pneumoniae-pneumonia-and-its-clinical-value
#13
JOURNAL ARTICLE
Jingcai Wang, Chunyan Guo, Lixin Yang, Peng Sun, Xiaoqing Jing
BACKGROUND: We investigated changes in microR-29c and microR-146a expression in the serum of children with Mycoplasma pneumoniae pneumonia, analysed their relationship with inflammatory factors and disease severity, and evaluated their diagnostic significance. METHODS: Fifty-six children with Mycoplasma pneumoniae pneumonia were enrolled as the Mycoplasma pneumoniae pneumonia group; 37 healthy children were enrolled as the control group. The microR-29c or microR-146a serum expression levels were determined using real-time quantitative reverse transcription polymerase chain reaction...
September 13, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37705032/influenza-viruses-circulation-in-a-tertiary-care-children-hospital-in-rome-a-comparison-between-2022-and-the-previous-5-years
#14
JOURNAL ARTICLE
Stefania Ranno, Luana Coltella, Giulia Linardos, Velia Chiara Di Maio, Luna Colagrossi, Leonarda Gentile, Eugenia Galeno, Marta Luisa Ciofi Degli Atti, Sebastian Cristaldi, Alberto Villani, Massimiliano Raponi, Carlo Federico Perno, Cristina Russo
BACKGROUND: Influenza surveillance aims to determine onset, duration and intensity of the seasonal Influence-like Illness (ILI); data collection begins in the week 42 of a year and ends in the week 17 of the following year. In this observational study, we report the experience of a tertiary care children hospital in Rome about Influenza viruses circulation during the calendar year 2022 (January-December) in comparison with the previous five years (2017-2021), with a special focus on the weeks 18-41, usually not under surveillance...
September 13, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37705014/exploring-changes-in-children-s-well-being-due-to-covid-19-restrictions-the-italian-epas-iss-study
#15
JOURNAL ARTICLE
Marco Giustini, Ilaria Luzi, Angela Spinelli, Silvia Andreozzi, Mauro Bucciarelli, Marta Buoncristiano, Paola Nardone, Silvia Ciardullo
BACKGROUND: While existing research has explored changes in health behaviours among adults and adolescents due to the COVID-19 outbreak, the impact of quarantine on young children's well-being is still less clear. Moreover, most of the published studies were carried out on small and non-representative samples. The aim of the EpaS-ISS study was to describe the impact of the COVID-19 pandemic on the habits and behaviours of a representative sample of school children aged mainly 8-9 years and their families living in Italy, exploring the changes in children's well-being during the COVID-19 pandemic compared to the immediately preceding time period...
September 13, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37697419/antibiotic-prophylaxis-for-ophthalmia-neonatorum-in-italy-results-from-a-national-survey-and-the-italian-intersociety-new-position-statements
#16
JOURNAL ARTICLE
Vito Mondì, Chryssoula Tzialla, Salvatore Aversa, Daniele Merazzi, Stefano Martinelli, Gabriella Araimo, Luca Massenzi, Giacomo Cavallaro, Luigi Gagliardi, Fiammetta Piersigilli, Mario Giuffrè, Simona Lozzi, Paolo Manzoni, Fabio Mosca, Irene Cetin, Vito Trojano, Herbert Valensise, Nicola Colacurci, Luigi Orfeo, Cinzia Auriti
BACKGROUND: Ophthalmia neonatorum is an acute conjunctivitis that occurs in newborns within the first month of life. The most serious infections are due to Chlamydia trachomatis and Neisseria gonorrhoeae, that may cause permanent damages. The use of ophthalmic prophylaxis varies widely around the world, according to the different health and socio-economic contexts. To date in Italy there is no a clear legislation regarding ophthalmia neonatorum prophylaxis at birth. METHODS: We invited all birth centers in Italy to carry out a retrospective survey relating the last three years...
September 11, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37679850/advances-for-pediatricians-in-2022-allergy-anesthesiology-cardiology-dermatology-endocrinology-gastroenterology-genetics-global-health-infectious-diseases-metabolism-neonatology-neurology-oncology-pulmonology
#17
REVIEW
Carlo Caffarelli, Francesca Santamaria, Ettore Piro, Simona Basilicata, Lorenzo D'Antonio, Bertrand Tchana, Sergio Bernasconi, Giovanni Corsello
The last year saw intensive efforts to advance knowledge in pediatric medicine. This review highlights important publications that have been issued in the Italian Journal of Pediatrics in 2022. We have chosen papers in the fields of allergy, anesthesiology, cardiology, dermatology, endocrinology, gastroenterology, genetics, global health, infectious diseases, metabolism, neonatology, neurology, oncology, pulmonology. Novel valuable developments in epidemiology, pathophysiology, prevention, diagnosis and treatment that can rapidly change the approach to diseases in childhood have been included and discussed...
September 8, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37679848/tuberous-sclerosis-complex-a-case-report-and-literature-review
#18
REVIEW
Yanlin Li, Zhihua Si, Wei Zhao, Cong Xie, Xu Zhang, Ju Liu, Jinzhi Liu, Zhangyong Xia
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with different initial symptoms and complex clinical manifestations. A 14-year-old female patient presented with persistent fever and severe headache. Medical imaging examinations revealed multiple abnormal intracranial lesions. The patient had previously been misdiagnosed with "encephalitis and acute disseminated encephalomyelitis" after visiting numerous hospitals. Eventually, by combing the characteristics of the case and genetic testing results, the patient was diagnosed with TSC accompanied by Mycoplasma pneumoniae infection...
September 8, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37670391/nationwide-survey-on-the-management-of-pediatric-pharyngitis-in-italian-emergency-units
#19
JOURNAL ARTICLE
Gregorio P Milani, Claudio Rosa, Naz Tuzger, Ilaria Alberti, Chiara Ghizzi, Stefania Zampogna, Angela Amigoni, Carlo Agostoni, Diego Peroni, Paola Marchisio, Elena Chiappini
BACKGROUND: Acute pharyngitis is a frequent reason for primary care or emergency unit visits in children. Most available data on pharyngitis management come from primary care studies that demonstrate an underuse of microbiological tests, a tendency to over-prescribe antibiotics and a risk of antimicrobial resistance increase. However, a comprehensive understanding of acute pharyngitis management in emergency units is lacking. This study aimed to investigate the frequency of rapid antigen test use to diagnose acute pharyngitis, as well as other diagnostic approaches, the therapeutic attitude, and follow-up of children with this condition in the emergency units...
September 5, 2023: Italian Journal of Pediatrics
https://read.qxmd.com/read/37670325/decreased-vitamin-d-levels-in-the-pediatric-population-after-covid-19-lockdown
#20
JOURNAL ARTICLE
Paolo Cavarzere, Romina Pausilli, Lara Nicolussi Prinicpe, Rossella Gaudino, Alessandra Guzzo, Gaetano Cantalupo, Franco Antoniazzi
BACKGROUD: SARS-Cov2 infection began to spread worldwide since December 2019; on March 2020, the World Health Organization characterized its related disease, named COVID-19, as a pandemic. In Italy, to contain the spread of infection a severe lockdown in the spring 2020 was instituted. Other less severe restrictions were imposed in the winter 2020-2021 and in the spring 2021. The containment measures caused a series of consequences for the population and, in particular, for children and adolescents that presented psychophysical problems...
September 5, 2023: Italian Journal of Pediatrics
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