journal
https://read.qxmd.com/read/37732523/barriers-related-to-oral-cancer-screening-diagnosis-and-treatment-in-karnataka-india
#21
JOURNAL ARTICLE
Vijay C R, Ramesh C, P Sridhar, C Ramachandra, Madhu Kumar
BACKGROUND: The most predominant cancer in India is Oral cancer. Annually 130,000 people yield to oral cancer in India, which translates into about 14 deaths per hour and 60-80% of patients present with advanced disease as compared to 40% in developed countries. AIM: To decide factors associated with primary, secondary and tertiary delays and identify reasons for a lack of follow-up. MATERIALS AND METHODS: This study was conducted at the Kidwai Memorial Institute of Oncology, Bengaluru...
September 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37732522/comparison-of-effectiveness-of-moringa-oleifera-leaves-extract-gel-2-with-retino-a-0-1-cream-for-treatment-of-oral-leukoplakia-double-blinded-randomized-control-trial
#22
JOURNAL ARTICLE
Sulem Ansari, Shivayogi Charantimath, Anabelle Fernandes, Jayraj B Malik, Prashanth Panta
AIM: The study aims to evaluate and compare the efficacy of Moringa oleifera leaf extract gel (2%) & Retino A cream (0.1%) in reducing the size of lesions in oral leukoplakia. OBJECTIVES: The present study aimed to evaluate the efficacy of two interventions, Moringa oleifera mucoadhesive gel and Retino-A cream, in reducing the size of lesions in patients with oral leukoplakia. Specifically, the objectives were: (1) to assess the efficacy of Moringa oleifera mucoadhesive gel in determining the reduction in lesion size, (2) to assess the efficacy of Retino-A cream in determining the reduction in lesion size, and (3) to compare the efficacy of Moringa oleifera mucoadhesive gel (2%) in determining the change in lesion size in oral leukoplakia patients...
September 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37732521/outcomes-of-breast-intraoperative-electron-beam-radiotherapy-ioert-case-series-of-single-institute-experience-in-saudi-arabia
#23
JOURNAL ARTICLE
Abdullah Alsuhaibani, Abdul Rahman Alqahtani, Abdulaziz Alsaif, Areej Bokhari, Basel AlMefleh, Yara Aldigi, Tareq Salah
INTRODUCTION: 85-90% of local recurrences after breastconserving surgery occurs within the index quadrant. Intraoperative radiotherapy may be a good alternative for eligible patients avoiding long course of adjuvant radiation. PATIENTS AND METHODS: Eligible patients were early stage node negative at least 50 years at time of inclusion, unicentric less than 30mm in diameter any hormone receptor status. 21 Gy was delivered intraoperatively, biologically equivalent to 58 to 60 Gy in standard fractionation using electron beam to 90% isodose line...
September 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283265/a-rare-tumor-in-adulthood-extrapancreatic-pancreatoblastoma
#24
JOURNAL ARTICLE
Ugur Topal, Begüm Çalım Gürbüz, Hasan Bektaş
Pancreatoblastoma is a rare malignant epithelial neoplasm of the pancreas. It primarily occurs in the pediatric population and is extremely uncommon in adults. A 64-year-old male patient with no known systemic disease presented to our clinic with abdominal pain and dyspeptic complaints. On physical examination, a tender epigastric mass was palpated. The patient was operated on with a preliminary diagnosis of gastrointestinal stromal tumor. Enbloc resection of the mass was performed. The transverse colon was segmentally resected with wedge resection of the gastric corpus...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283264/metastatic-small-cell-carcinoma-of-a-male-breast-a-case-report-and-review-of-the-literature
#25
JOURNAL ARTICLE
Nadin Shawar Al Tamimi, Yousra Bennouna, Mohammed El Fadli, Rhizlane Belbaraka
Neuroendocrine breast cancers are rare tumors that were recognized as a distinct entity by WHO classification in 2003. It is much rarer in male breast cancer. Diagnosis is based on immunochemical analysis in which the expression of at least one neuroendocrine marker is required, associated with the exclusion of another primary site of the tumor. These tumors have a worse long-term outcome compared to other breast cancers. Small cell carcinoma of the breast is a high-grade subtype, presents with more advanced disease, and has a poorer prognosis compared with other neuroendocrine breast subtypes...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283263/treatment-process-of-primary-prostate-leiomyosarcoma-a-rare-case-report
#26
JOURNAL ARTICLE
Denis Cetin, Mustafa Murat Mıdık, Mustafa Mustafayev, Burcak Karaca
Prostate sarcoma is an extremely rare malignancy that accounts for only %0.1 of all neoplasms of the prostate gland. Primary prostate leiomyosarcoma (PLSOP) is the most common subtype in adults. Due to the fact that it is an extremely rare malignancy, case reports have been reported frequently and several publications in the form of case series. The number of case reports in the world is less than 200. Our opinion is that publishing such rare diseases and bringing them to the literature will have positive benefits both scientifically and for the patients...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283262/peptic-ulcer-disease-and-its-treatments-and-risk-of-pancreatic-cancer-a-meta-analysis
#27
JOURNAL ARTICLE
Nasser Alkhushaym, Goot Albuainain, Tuqa A AbuShaheen, Mohammed Y Alshami, Ali S Almutairi, Ayman Ahmed Sakr, Ayat S Almuhayshi
BACKGROUND AND OBJECTIVE: Pancreatic cancer (PC) is the seventh leading cause of death among cancers mortality. Pancreatic carcinogenesis remains poorly understood. There is still an urge to allocate other related risk factors that may help in better recognition of this pathogenesis. There is increasing evidence suggested that peptic ulcer disease (PUD), and its treatment might affect the development of PC however, studies findings reported conflicting results. Our meta-analysis aimed to study the association between PUD and its treatments (proton pump inhibitors [PPIs] and histamine-2 receptor antagonists [H2RAs]) and risk of PC...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283261/does-the-nightmare-of-distressing-complications-of-groin-dissection-over-with-river-flow-incision-experience-of-240-dissections-from-tertiary-referral-oncology-centre-india
#28
JOURNAL ARTICLE
M D Ray, J R Jeena Josephin, Premanand N
OBJECTIVE: Groin dissection has been a nightmare for many surgeons due to its higher morbidity especially flap necrosis. Various modifications in incisions have been described in the literature to reduce the complications but with variable outcomes. By our novel "River Flow" incision technique, we have significantly reduced the procedure related complications without compromising onco surgical principles. METHODS: A prospective longitudinal clinical observational study was designed after Institutional Ethical Committee clearance, aiming to minimize the rate of complications, especially flap necrosis...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283260/egfr-expression-in-gallbladder-carcinoma-in-north-indian-population
#29
JOURNAL ARTICLE
Vikash, Vikas Kailashiya, Mohan Kumar, Puneet
OBJECTIVE: Gallbladder carcinoma is the most frequent biliary tract carcinoma with over all very poor prognosis. Epidermal growth factor receptor (EGFR) is known to be involved in carcinogenesis and overexpressed in various malignancies including head and neck, breast, lung and colon carcinomas. This study was done to explore the expression of EGFR in gallbladder carcinoma cases in the north Indian population so that it may be used as a therapeutic target in these patients. MATERIALS AND METHODS: 59 cases of gallbladder carcinoma diagnosed by histopathological examination were included in study...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283259/study-of-efficacy-and-toxicity-of-capecitabine-maintenance-after-response-to-docetaxel-cisplatin-and-5-fluracil-based-chemotherapy-in-advanced-carcinoma-stomach
#30
JOURNAL ARTICLE
Udip Maheshwari, Pankaj Goyal, Varun Goel, Nivedita Patnaik, Venkata Pradeep Babu Koyyala, Krushna Chaudhari, D C Doval, Vineet Talwar
BACKGROUND: Advanced gastric cancer is associated with poor survival despite chemotherapy. Maintenance chemotherapy has been successfully tried in lung cancer and colorectal cancers however there is scarce literature on maintenance therapy in advanced gastric cancer. We report a prospective non-randomized single-arm trial of capecitabine maintenance after response to docetaxel, cisplatin, and 5-Flurouracil-based chemotherapy. METHODS: 50 patients with advanced gastric cancer, who had achieved response or had stable disease after 6 cycles of Docetaxel, Cisplatin, and 5-Flurouracil (D 75 mg/m2, C 75 mg/m2, FU 750 mg/m2/d d1-d5, q3 weeks) chemotherapy were prospectively selected to receive maintenance chemotherapy with capecitabine (1000mg/ m2 bid d1-d14 q21 days) until progression...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283258/variants-of-human-mucin-genes-in-clear-cell-renal-cell-carcinoma-and-their-potential-prognostic-and-predictive-values
#31
JOURNAL ARTICLE
Jamal Zekri, Mohammed A Baghdadi, Abdelrazak Meliti, Turki M Sobahy, Saba Imtiaz
BACKGROUND: There is no reliable prognostic and predictive biomarkers for clear cell renal cell carcinoma (cc-RCC). METHODS: DNA from 47 cc-RCC tissue samples were sequenced using next generation sequencing and a customized gene panel testing for tumor-driver genes including 19 Mucin genes. RESULTS: Distinctive variants in 12 Mucin genes were present in all samples. These genes are: MUC2, MUC3A, MUC4, MUC5AC, MUC5B, MUC6, MUC7, MUC12, MUC16, MUC17, MUC19, and MUC22...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283257/survival-outcomes-of-post-mastectomy-breast-cancer-patients-treated-with-hypofractionated-radiation-treatment-compared-to-conventional-fractionation-a-retrospective-cohort-study
#32
JOURNAL ARTICLE
Ciniraj Raveendran, Suma Susan Meloot, I Yadev
INTRODUCTION: For post-mastectomy patients, radiation treatment with conventional fractionation with a treatment duration of five weeks was the frequently used regimen, whereas hypofractionated regimens are recently used in the adjuvant treatment, which has a shorter treatment time over three weeks. We determined to estimate the treatment outcome by survival analysis between these two fractionation schedules to determine if any difference exists between these two groups. METHODS: We retrospectively reviewed the data of 348 breast cancer patients who had received adjuvant radiation treatment to the breast from January 2010 to December 2013...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283256/prevalence-of-brca1-and-brca2-mutations-among-high-risk-bahraini-patients-with-breast-cancer
#33
JOURNAL ARTICLE
Zain Bukamal, Amal AlRayes
OBJECTIVE: The purpose is to study the prevalence of BRCA1 and BRCA2 mutations in high-risk Bahraini patients diagnosed with breast cancer, its relation to family history, and to determine the clinicopathologic features of breast cancer associated with these genetic mutations, over a period of 7 years. BACKGROUND: Breast cancer is the most common type of cancer occurring in women and the second most common type generally. Approximately 12% of women worldwide will develop carcinoma of the breast sometime during their life...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283255/tumor-stroma-ratio-in-er-her2-breast-cancer-is-it-a-tool-for-treatment-decision
#34
JOURNAL ARTICLE
Choukri Elmhadi, Mohammed Allaoui, Meryem Zerrik, Mohammed Oukabli, Rachid Tanz, Mohammed Ichou
PURPOSE: The primary aim of this study is to determine the relationship between tumor-stroma ratio (TSR) and traditional prognostic factors in luminal early breast cancer in women treated at the medical oncology department of the military hospital of Rabat in Morocco. METHODS: A retrospective study was performed on primary invasive ER+/HER2- breast cancer in the period from January 1st, 2019 to December 31st, 2019. Prognostic factors included age, tumour size, lymph nodes status, Scarff-Bloom-Richardson grading, lymphovascular invasion (LVI), Ki67 and the stage of the disease...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/37283254/identification-of-the-physiological-dimension-and-selfconcept-among-husbands-of-iranian-women-with-mastectomy-a-directed-content-analysis
#35
JOURNAL ARTICLE
Marzieh Beigom Bigdeli Shamloo, Nasrin Elahi, Marziyeh Asadi Zaker, Kourosh Zarea, Armin Zareiyan
BACKGROUND: Breast cancer, as the most prevalent cancer among females, exerts physical and mental impacts on both patients and their husbands. The present study aimed at investigating various dimensions of self-concept among husbands of Iranian women with mastectomy. METHODS: This study was conducted on 23 patients with mastectomy and their husbands and therapists using directed content analysis according to Callista-Roy adaptation model. The participants were interviewed regarding how they coped with cancer through video call, and 'physical dimensions' and 'self-concept' subcategories were identified...
May 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/36804166/ghost-cell-odontogenic-carcinoma-with-sarcomatous-transformation-report-of-a-rare-case-with-review-of-literature
#36
REVIEW
Sithara Aravind, Jasmin Jose, Sangeetha K Nayanar, Sajith Babu T P
Ghost Cell Odontogenic Carcinoma is a rare malignant odontogenic tumor that can appear as "de novo " or arises from malignant transformation of preexisting benign calcifying odontogenic cysts or dentinogenic ghost cell tumors after multiple recurrences. Ghost cell odontogenic carcinoma is histopathologically characterized by ameloblast-like islands of epithelial cells with aberrant keratinization, simulating a ghost cell, with varying amounts of dysplastic dentine. This article reports an extremely rare case of ghost cell odontogenic carcinoma with foci of sarcomatous change, involving maxilla andnasal cavity which arose from a previously existing recurrent calcifying odontogenic cysts in a 54-year-old man and reviews the features of this unusual and rare tumor...
January 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/36804165/pilomatrix-carcinoma-rare-presentation-of-an-unusual-cutaneous-malignancy
#37
JOURNAL ARTICLE
Raja Anand, Malik Kanuj, Sundersingh Shirley
INTRODUCTION OR BACKGROUND: Pilomatrix carcinoma is a rare malignant neoplasm arising from the root of hair follicles, with only 150 cases described in the world literature. It is most commonly seen in the head and neck region. CASE PRESENTATION: We describe a case of malignant pilomatrix carcinoma in a 62-year-old gentleman presenting as a solitary globular mass over the right anterior chest wall along with a brief review of literature. DISCUSSION AND CONCLUSION: Surgical excision with a wide margin is the current standard of care for chest wall pilomatrix carcinoma and is associated with the least recurrence...
January 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/36804164/desmoid-tumor-of-the-rectus-abdominis-with-urinary-bladder-involvement-a-case-report-and-review-of-literature
#38
REVIEW
Moath Alfentoukh, Abdulwahab Salih, Mukhtar E Hassan, Osamah Alghamdi, Khadija A Alkhawaja, Mustafa A Ibrahim, Elsanousi Ibrahim Sabir
Desmoid tumors (DTs) account for 3% of all soft tissue tumors. They are benign and have no malignant potential with a favorable prognosis, and predominantly occur in young women. The pathogenesis and clinical behavior of DTs are still uncertain. In addition, most cases of DTs were associated with abdominal trauma (including surgery), while genitourinary involvement seemed to be quite rare. Up to now, there has been only one DT case with urinary bladder involvement reported in the literature. We, Hereby, report a 67-year-old male patient with left lower abdominal pain while micturition...
January 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/36804163/salivary-lactate-dehydrogenase-as-a-potential-biomarker-in-oral-potentially-malignant-disorders-and-head-neck-cancer-a-systematic-review-and-meta-analysis
#39
JOURNAL ARTICLE
Lokesh Kumar S, Zameera Naik, Vasanti Lagali-Jirge, Sridhar M, Arun Panwar, Vaishali Keluskar
BACKGROUND: The prognosis of head &neck cancer (HNC) depends on its early detection, diagnosis, and treatment, which has advocated a search for a simple, reliable, noninvasive, cost-effective tool to aid in the same. Salivary lactate dehydrogenase has gained interest in recent years, meeting the above requisite. OBJECTIVES: To evaluate the levels of salivary lactate dehydrogenase in patients with oral potentially malignant disorders (OPMD), HNC, and in the healthy control group (CG); to find the correlation, grade-wise and genderwise difference between them; and to assess whether it can be used as a potent biomarker in OPMD and HNC...
January 2023: Gulf Journal of Oncology
https://read.qxmd.com/read/36804162/association-of-clinical-staging-of-osmf-with-habit-of-smokeless-tobacco-consumption-hospital-based-cross-sectional-study
#40
JOURNAL ARTICLE
Ekta A Malvania, Shilpa J Parikh, Vaishanavi Pathak, Pranay B Nayi, Tadrushi A Gandhi, Nidhi N Patel
BACKGROUND: Oral submucous fibrosis (OSMF), a premalignant condition of oral cavity is associated with usage of smokeless tobacco. The growing prevalence and cultural acceptance of consumption of flavored arecanut and related products along with traditional smokeless tobacco products are confounding the scenario. OBJECTIVES: To find out clinical staging of OSMF and correlate it with consumption of smokeless tobacco usage related factors among subjects with oral sub mucous fibrosis in Ahmedabad city...
January 2023: Gulf Journal of Oncology
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