Gulf Journal of Oncology

INTRODUCTION OR BACKGROUND: Clear cell meningioma is a rare WHO grade 2 tumour and runs an aggressive course. Tyrosine crystals are very uncommon in meningioma. CASE PRESENTATION: We present a case of a 43-year female with right middle and posterior cranial fossa space occupying lesion (SOL) diagnosed as clear cell meningioma with presence of numerous tyrosine crystals. DISCUSSION AND CONCLUSION: Whether these crystals are incidentally noted or if there is an actual relationship of these crystals with tumour environment must be found as they are seen in many other conditions too...

Artificial intelligence (AI) has truly revolutionized many fields, including healthcare. In radiation oncology, AI has emerged as a powerful tool for improving the speed, accuracy and overall quality of radiotherapy treatments. The radiotherapy workflow involves complex processes that require coordination between healthcare professionals with diverse skills. AI and deep learning methods offer unprecedented potential to transform this workflow by leveraging imaging modalities, digital data processing and advanced software algorithms...

BACKGROUND: Prostate cancer (PC) is the second most common cancer in men worldwide. It's the second leading cause cancer men in death. Prognostic tests based on molecular and biomarker analysis of tumor tissue may improve risk stratification of prostate cancer 2. MATERIALS AND METHODS: After a search on Pubmed for PC biomarkers, 72 papers responded to the objectives and will be included in the review. RESULTS: A plethora of biomarkers are predictive for the prognosis of PC and its response to certain therapies, while others, once thought to be indicative of prognosis in PC, were not...

BACKGROUND: Stereotactic radiosurgery is a well-known and influential management option for meningioma. This article aims to highlight the most cited publications on this topic. METHODS: All Scopus articles published in English under Stereotactic radiosurgery and meningioma were sorted according to the number of citations. The keywords used were: "Stereotactic radiosurgery, SRS, Meningioma, Intracranial meningioma". The top 100 cited articles meeting the criteria were included...

BACKGROUND: Cancer is a medical condition where some cells of the body reproduce uncontrollably and metastasize to other parts of the body. This study attempts to review the effect of physiotherapy application on head and neck, lung and breast cancer survivors on important clinical outcomes such as pain, strength, fatigability, coordination, balance, activities of daily living (ADLs), psychosocial aspects, cognitive aspects, and quality of life (QoL) Methods: A systematic review was conducted following PRISMA guidelines...

INTRODUCTION: Several studies evaluated the outcomes of cancer patients treated with septic shock in intensive care units (ICUs), but limited data is available on the long-term outcomes of this patient population. In this report, we aimed to evaluate the one-year mortality in cancer patients who were discharged alive following their intensive care unit (ICU) admission for septic shock. PATIENTS AND METHODS: A retrospective study that was conducted at an oncologic ICU of a comprehensive cancer center...

INTRODUCTION: We assessed the effectiveness of URS-SM procedure for ureteral stones located in different parts of ureter and to determine outcomes in terms of success rate, complications, and operation time. METHODS: After obtaining approval of the Institutional Clinical Board of urology, we reviewed data of consecutive 102 patients treated at our Urology Department with URSSM procedure in cohort study January 2023-May 2023. RESULTS: There were 44 (43,2%) men and 58 (56,8%) women with a mean age of 43...

BACKGROUND: Radiation therapy in Head and neck cancers often leads to xerostomia which often leads to a decline in quality of life. The aim of the study was to compare xerostomia among cancer patients undergoing IMRT and VMAT techniques for head and neck malignancies and follow them up via quality of life assessment. METHODOLOGY: It was a hospital based prospective study with follow up at 0, 3 and 6 months among total 80 patients divided in 2 groups of VMAT and IMRT respectively...

BACKGROUND: Dentists play a key role in and the management of oral cancer treatment complications. This study aimed to evaluate the general and specialist dentists' knowledge and practice regarding the dental management of such patients. METHODS: This cross-sectional analytic study was conducted among 370 general and specialist dentists in Isfahan, Iran 2020. A self-administrative questionnaire was designed and validated. The questionnaire had 18 questions in Knowledge section, 10 questions to measure performance, and 3 questions to evaluate dentist's opinion toward their management ability...

INTRODUCTION: Breast cancer is the most frequent cancer among Emirati women and is the second leading cause of death among women in the UAE. To date, published studies regarding breast cancer in the UAE have investigated a mixed population of different ethnicities with a low percentage of UAE nationals. This is the first study to highlight the clinical and pathological data of a large cohort of exclusively Emirati national breast cancer patients diagnosed at a tertiary care medical facility...

INTRODUCTION: Papillary squamotransitional cell carcinoma (PSTCC) arising from the uterine cervix is a distinctive histomorphological subtype of squamous cell carcinoma (SCC) not otherwise specified (NOS) of cervical epithelial tumors. AIM: The present study was undertaken to study the histopathological features and immunoexpression of CK7, CK20, p53 and Ki-67 in PSTCC of the cervix. MATERIALS AND METHODS: This study included 43 cases of PSTCC of cervix...

INTRODUCTION: CT information of the target undergoing motion/movement during its scanning has been questioned by many researchers for its preciseness as well as accuracy. The present study was taken with aim to validate the racimosa wood as lung equivalent and to assess the uncertainty in volume estimation during virtual simulation of non-static target of known dimension such as in lung cancer radiotherapy. MATERIALS AND METHODS: The racemosa wood was validated as lung equivalent material with the help of two methods...

Glioblastoma (GBM) with Primitive Neuroectodermal tumor (PNET) like features is an extremely rare tumor showing dual features of malignant glioma and primitive neuroectodermal tumour occurring mostly in adults. It poses diagnostics dilemma to the neuropathologist and treating oncologist team because of its rarity, tendency to spread to cerebrospinal fluid and dismal prognosis. We have described this tumor in a 11 years old male child in this case report. Keywords: glioma,glioblastoma,primitive neuroectodermal tumor, variant, pediatric...

INTRODUCTION: Scrotal cancer is a very rare disease, with the most common subtype being squamous cell carcinoma. Metastatic carcinoma to the scrotal wall is very rare. A histological finding of adenocarcinoma in a scrotal malignancy invariably suggests a metastasis from another primary cancer. We describe an enigmatic case of metastatic adenocarcinoma to the scrotum managed as metastatic adenocarcinoma of unknown origin. Attempts to identify a primary cancer were complicated by ambiguous diagnostic results...

Urinary tract hemangiomas are uncommon entity to urologists, despite their benign nature and course; they can cause significant patient's hemodynamic instability or distress if not recognized and managed properly. Here, we present a case of urethral hemangioma with its treatment, follow-up course and review of literature of similar cases. Introduction: Bloody urine or urethral bleeding can be the initial presentation of a number of different medical and surgical conditions, some of which are benign and others are malignant, when encountered, they are alarming and must be evaluated thoroughly...

The treatment of cancer has evolved as our understanding of the underlying biological processes has improved. Yet, the efficient delivery of cancer therapeutics remains a major challenge in the filed necessitating a multidisciplinary approach that integrates knowledge obtained from diverse fields, such as chemistry, biology, engineering, and medicine. Cancer treatment aims to remove all or most of the tumor as possible and to prevent the recurrence or spread of the primary tumor. Cancer treatment involves a careful examination of the available options, which may include a combination of the major treatment methods, such as surgery with chemotherapy and/or radiation therapy...

UNLABELLED: The effectiveness of radiotherapy treatment is influenced by the position of beam focal spot; therefore, it is important to verify the beam focal spot periodically. In this study the beam focal spot offset is measured using an electronic portal imaging (EPID) based technique and co- rotational penumbra modulation technique(CPM). MATERIALS AND METHODS: This method utilizes one set of jaws and the multileaf collimator (MLC) to form a symmetric field and then a 180o collimator rotation was utilized to determine the radiation isocenter defined by the jaws and the MLC, respectively...

INTRODUCTION: In the realm of oncology, the development of TIVAD (chemoport) has been a blessing for cancer patients, freeing them from having to undergo numerous recurrent venepunctures throughout their treatment. The External Jugular Vein cut-down has been the standard procedure for administering chemotherapy to cancer patients at our institution. Here, we discuss our experience with the External Jugular Vein cut-down Chemoport Insertion Technique and the outcomes it produced. MATERIALS AND METHODS: We performed a prospective observational study and included all patients who underwent the open External Jugular Vein cut-down technique of Chemoport Insertion from January 2019 to January 2022 in the Department of Surgical Oncology at our hospital...

BACKGROUND: Bladder cancer (BC) is the most common malignant tumor of the urinary tract and the 11th most frequent cancer worldwide. BC is the 2nd most common cancer in Lebanon in men and women. MATERIALS AND METHODS: After searching for patients records in the pathology and oncology database, we identified those who underwent a cystectomy between 2017 and 2019 in our hospital, Hotel Dieu de France - Beirut. We selected for the study the patients who have undergone a cystectomy for MIBC...

INTRODUCTION: The triple assessment, which combines a clinical examination, radiological imaging, and pathology, is used to assess the breast mass. The open excision of the suspicious lesion is the gold standard for breast biopsy techniques. However, because an excisional biopsy always results in a scar, many surgeons are considering less invasive, alternative methods due to the cost and morbidity of this operation. Image-guided percutaneous core-needle biopsy has recently gained popularity in identifying palpable and non-palpable breast lesions...