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Journals Nature Reviews. Gastroenterolo...

Nature Reviews. Gastroenterology & Hepatology

https://read.qxmd.com/read/38783126/positive-phase-iii-trials-for-ileal-bile-acid-transporter-inhibitors
#1
JOURNAL ARTICLE
Katrina Ray
No abstract text is available yet for this article.
May 23, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38778180/sex-and-ethnic-disparities-persist-in-hepatitis-b-management
#2
JOURNAL ARTICLE
Katrina Ray
No abstract text is available yet for this article.
May 22, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38773285/a-single-cell-multiomics-profile-of-fontan-associated-liver-disease
#3
JOURNAL ARTICLE
Katrina Ray
No abstract text is available yet for this article.
May 21, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38773284/microbiota-and-colorectal-cancer-controlling-for-confounders-challenges-associations
#4
JOURNAL ARTICLE
Katrina Ray
No abstract text is available yet for this article.
May 21, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38763974/pleasurable-and-problematic-receptive-anal-intercourse-and-diseases-of-the-colon-rectum-and-anus
#5
REVIEW
Daniel R Dickstein, Collin R Edwards, Catherine R Rowan, Bella Avanessian, Barbara M Chubak, Christopher W Wheldon, Priya K Simoes, Michael H Buckstein, Laurie A Keefer, Joshua D Safer, Keith Sigel, Karyn A Goodman, B R Simon Rosser, Stephen E Goldstone, Serre-Yu Wong, Deborah C Marshall
The ability to experience pleasurable sexual activity is important for human health. Receptive anal intercourse (RAI) is a common, though frequently stigmatized, pleasurable sexual activity. Little is known about how diseases of the colon, rectum, and anus and their treatments affect RAI. Engaging in RAI with gastrointestinal disease can be difficult due to the unpredictability of symptoms and treatment-related toxic effects. Patients might experience sphincter hypertonicity, gastrointestinal symptom-specific anxiety, altered pelvic blood flow from structural disorders, decreased sensation from cancer-directed therapies or body image issues from stoma creation...
May 19, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38750268/telemedicine-for-hepatitis-c-virus-treatment-in-opioid-treatment-programmes
#6
JOURNAL ARTICLE
Jordan Hindson
No abstract text is available yet for this article.
May 15, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38750267/development-of-mkk4-inhibitors-for-liver-regeneration
#7
JOURNAL ARTICLE
Jordan Hindson
No abstract text is available yet for this article.
May 15, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38744960/rhythmicity-of-infant-microbiota-and-dietary-effects
#8
JOURNAL ARTICLE
Jordan Hindson
No abstract text is available yet for this article.
May 14, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38744959/multi-omic-links-between-gut-microbiome-and-cardiovascular-disease
#9
JOURNAL ARTICLE
Jordan Hindson
No abstract text is available yet for this article.
May 14, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38740978/mitochondrial-function-and-gastrointestinal-diseases
#10
REVIEW
Parsa S Haque, Neeraj Kapur, Terrence A Barrett, Arianne L Theiss
Mitochondria are dynamic organelles that function in cellular energy metabolism, intracellular and extracellular signalling, cellular fate and stress responses. Mitochondria of the intestinal epithelium, the cellular interface between self and enteric microbiota, have emerged as crucial in intestinal health. Mitochondrial dysfunction occurs in gastrointestinal diseases, including inflammatory bowel diseases and colorectal cancer. In this Review, we provide an overview of the current understanding of intestinal epithelial cell mitochondrial metabolism, function and signalling to affect tissue homeostasis, including gut microbiota composition...
May 13, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38693299/transgender-health-care-in-the-united-states-legal-ethical-and-practical-concerns-for-gastroenterologists-in-a-changing-landscape
#11
JOURNAL ARTICLE
Sarah Singh, Nikki Duong, Laura Targownik, Sonali Paul, Christopher Vélez, Lauren D Feld
No abstract text is available yet for this article.
May 1, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38664536/pouchitis-pathophysiology-and-management
#12
REVIEW
Bo Shen
Pouchitis is an acute or chronic inflammatory disease of the ileal reservoir. It is common after restorative proctocolectomy with ileal pouch-anal anastomosis, and treatment of chronic antibiotic-refractory pouchitis has proven challenging. Most cases of acute pouchitis evolve into chronic pouchitis. The aetiology of acute pouchitis is likely to be partly related to the gut microbiota, whereas the pathophysiology of chronic pouchitis involves abnormal interactions between genetic disposition, faecal stasis, the gut microbiota, dysregulated host immunity, surgical techniques, ischaemia and mesentery-related factors...
April 25, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38654090/spatial-genomics-mapping-human-steatotic-liver-disease
#13
REVIEW
Kylie P Matchett, Jasmin Paris, Sarah A Teichmann, Neil C Henderson
Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as non-alcoholic fatty liver disease) is a leading cause of chronic liver disease worldwide. MASLD can progress to metabolic dysfunction-associated steatohepatitis (MASH, formerly known as non-alcoholic steatohepatitis) with subsequent liver cirrhosis and hepatocellular carcinoma formation. The advent of current technologies such as single-cell and single-nuclei RNA sequencing have transformed our understanding of the liver in homeostasis and disease...
April 23, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38627537/artificial-intelligence-in-liver-cancer-new-tools-for-research-and-patient-management
#14
REVIEW
Julien Calderaro, Laura Žigutytė, Daniel Truhn, Ariel Jaffe, Jakob Nikolas Kather
Liver cancer has high incidence and mortality globally. Artificial intelligence (AI) has advanced rapidly, influencing cancer care. AI systems are already approved for clinical use in some tumour types (for example, colorectal cancer screening). Crucially, research demonstrates that AI can analyse histopathology, radiology and natural language in liver cancer, and can replace manual tasks and access hidden information in routinely available clinical data. However, for liver cancer, few of these applications have translated into large-scale clinical trials or clinically approved products...
April 16, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38627536/a-crucial-fusobacterium-nucleatum-clade-in-colorectal-cancer
#15
JOURNAL ARTICLE
Katrina Ray
No abstract text is available yet for this article.
April 16, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38580787/promoting-allyship-to-support-and-uplift-the-lgbtqia-community
#16
JOURNAL ARTICLE
Daniel J Huynh, Sonali Paul, Nikki Duong
No abstract text is available yet for this article.
April 5, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38575683/publisher-correction-gastrointestinal-and-brain-barriers-unlocking-gates-of-communication-across-the-microbiota-gut-brain-axis
#17
María R Aburto, John F Cryan
No abstract text is available yet for this article.
April 4, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38575682/the-changing-metabolic-landscape-of-bile-acids-keys-to-metabolism-and-immune-regulation
#18
REVIEW
Ipsita Mohanty, Celeste Allaband, Helena Mannochio-Russo, Yasin El Abiead, Lee R Hagey, Rob Knight, Pieter C Dorrestein
Bile acids regulate nutrient absorption and mitochondrial function, they establish and maintain gut microbial community composition and mediate inflammation, and they serve as signalling molecules that regulate appetite and energy homeostasis. The observation that there are hundreds of bile acids, especially many amidated bile acids, necessitates a revision of many of the classical descriptions of bile acids and bile acid enzyme functions. For example, bile salt hydrolases also have transferase activity. There are now hundreds of known modifications to bile acids and thousands of bile acid-associated genes, especially when including the microbiome, distributed throughout the human body (for example, there are >2,400 bile salt hydrolases alone)...
April 4, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38565649/improving-culturally-safe-engagement-with-sexual-and-gender-minority-populations
#19
JOURNAL ARTICLE
Newsha Nikzad, Nikki Duong, Sonali Paul
No abstract text is available yet for this article.
April 2, 2024: Nature Reviews. Gastroenterology & Hepatology
https://read.qxmd.com/read/38565648/new-understanding-of-hepatobiliary-mri
#20
JOURNAL ARTICLE
Catherine M Pastor, Valérie Vilgrain
No abstract text is available yet for this article.
April 2, 2024: Nature Reviews. Gastroenterology & Hepatology
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