Gustavo Oliveira Campos, Alexandre Henrique Dos Reis Prado, Isabella Figueiredo de Assis Macedo, Isabella da Costa Ferreira, Gabriela da Costa Ferreira, Francine Benetti, Isabella Faria da Cunha Peixoto, Ana Cecília Diniz Viana
INTRODUCTION: Foraminal Enlargement (FE) is a cleaning performed in the apical-most region of the tooth, in order to optimize root disinfection. This systematic review evaluated the influence of FE during root canal treatment on bacterial reduction and repair of the periapical lesion. MATERIALS AND METHODS: Searches in PubMed/MEDLINE, Scopus, Cochrane Library, Web of Science, Embase, Scielo, Lilacs and OpenGrey were performed until January-2024. Ex vivo and in vivo studies evaluating the effects of FE in the bacterial reduction and repair of the periapical lesion were included, respectively, followed by risk of bias assessment (modified version of Joanna Briggs Institute's for ex vivo studies and Systematic Review Centre for Laboratory animal Experimentation's risk of bias tools for in vivo studies)...
2024: Iranian Endodontic Journal