Hadi Zare-Zardini, Hossein Soltaninejad, Adel Ghorani-Azam, Mohammad Javad Forouzani-Moghaddam, Sima Mozafri, Zohreh Akhoundi-Meybodi, Farzad Ferdosian, Fatemeh Jabinian
Developing targeted and slow-release antibiotic delivery systems can effectively reduce drug overdose and side effects. This study aimed to investigate the antimicrobial activity of vancomycin-loaded soy protein nanoparticles (vancomycin-SPNs). For the preparation of SPNs, the desolvation method was applied in different concentrations of vancomycin and soy protein (15:5, 10:15, 6:20, 8:25, and 10:30 of vancomycin:soy protein). Scanning electron microscope (SEM), transmission electron microscopy (TEM), dynamic light scattering (DLS), and FTIR were used for nanoparticle characterization...
2022: Interdisciplinary Perspectives on Infectious Diseases