Mi Luo, Abdul Rehman, Soha Haque, Saba Izhar, Fauzia Perveen, Muhammad Haris, Mostafa A Abdel-Maksoud, Ibrahim A Saleh, Naser Zomot, Abdul Malik, Abdulaziz Alamri, Ahmad S Kodous, Mohammed Aufy, Mohamed Y Zaky, Muhammad Zaeem, Yasir Hameed, Junwei Li
OBJECTIVES: To elucidate the expression levels and prognostic value of the Lipoyltransferase 2 (LIPT2) gene in a pan-cancer view. METHODOLOGY: Our study comprehensively investigated the role of LIPT2 in pan-cancer, combining bioinformatics analyses with experimental validations. RESULTS: Analysis of LIPT2 mRNA expression across various cancers revealed a significant up-regulation in 18 tumor types and down-regulation in 8 types, indicating its diverse involvement...
2024: American Journal of Translational Research