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American Journal of Rhinology & Allergy

https://read.qxmd.com/read/38462932/head-down-topical-sinus-rinses-cut-your-way-to-success
#1
LETTER
Arthur William Wu, Dennis Mansfield Tang, Gene C Liu
No abstract text is available yet for this article.
March 11, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38456692/quantification-of-budesonide-retained-in-the-sinonasal-cavity-after-high-volume-saline-irrigation-in-post-operative-chronic-rhinosinusitis
#2
JOURNAL ARTICLE
Paige A Shipman, Bhuvanesh Yathavan, Amarbir S Gill, Chelsea E Pollard, Venkata Yelleppedi, Hamidreza Ghandehari, Jeremiah A Alt, Abigail Pulsipher, Kristine A Smith
BACKGROUND: Budesonide high-volume saline irrigations (HVSIs) are routinely used to treat chronic rhinosinusitis (CRS) due to improved sinonasal delivery and efficacy compared to intranasal corticosteroid sprays. The off-label use of budesonide is assumed to be safe, with several studies suggesting the systemically absorbed dose of budesonide HVSI is low. However, the actual budesonide dose retained in the sinonasal cavity following HVSI is unknown. The objective of this study was to quantify the retained dose of budesonide after HVSI...
March 8, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38454786/biofilm-producing-bacteria-and-quality-of-life-after-endoscopic-sinus-surgery-in-patients-with-chronic-rhinosinusitis-with-nasal-polyposis
#3
JOURNAL ARTICLE
Jovica Milovanović, Dragana D Božić, Bojan Pavlović, Ana Jotić, Snežana Brkić, Ivana Ćirković
BACKGROUND: Chronic rhinosinusitis (CRS) is one of the most common health disorders in humans and has a major impact on health-related quality of life (HRQoL). Of the many factors contributing to the etiology of CRS, less is known about the correlation between CRS and bacterial biofilms and their impact on HRQoL. OBJECTIVE: The aim of this prospective study was to investigate the relationship between biofilm-producing bacteria and patients' objective findings and HRQoL...
March 7, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38444220/early-endonasal-dacryocystorhinostomy-for-acute-dacryocystitis-a-systematic-review-and-meta-analysis
#4
REVIEW
Jia Li, Jihong Wang, Changling Sun
OBJECTIVE: The aim of this meta-analysis is to compare the outcomes of early endonasal dacryocystorhinostomy (DCR) with delayed DCR in the treatment of acute dacryocystitis (AD). METHODS: A comprehensive electronic search of PubMed, Embase, Web of Science, and the Cochrane Library databases was conducted up to November 11, 2023. Data synthesis was performed using Review Manager 5.4, and forest plots were generated for each outcome measure. Potential publication bias was assessed using funnel plots and Egger's test...
March 5, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38444214/endoscopic-and-radiologic-central-compartment-disease-as-predictors-of-perennial-inhalant-allergen-sensitization-in-chronic-rhinosinusitis
#5
JOURNAL ARTICLE
Linus Lau, Terese Low, Yew Kwang Ong, Xu Xinni
BACKGROUND: Central compartment atopic disease (CCAD) is a recently described variant of chronic rhinosinusitis (CRS) strongly associated with atopy. The association between central compartment disease (CCD) and inhalant allergy is not well established in South-East Asia, where perennial allergic rhinitis is common. OBJECTIVES: The primary objective was to evaluate endoscopic and radiologic CCD as predictors of perennial allergen sensitization in primary CRS. The secondary objective was to compare clinical characteristics of CCAD with other CRS subtypes (CRSwNP and CRSsNP)...
March 5, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38378005/expression-of-nmu-and-nmur1-in-tryptase-positive-mast-cells-and-pbls-in-allergic-rhinitis-patients-nasal-mucosa
#6
JOURNAL ARTICLE
Wei Zhao, Yunfang An, Fengli Cheng, Changqing Zhao
BACKGROUND: The neuropeptide U (NMU) has been proven to elicit the release of mediators from mast cells (MCs) through its receptor NMUR1 in allergic inflammatory models. However, little is known about the correlations between NMU and MCs in human allergic rhinitis (AR). OBJECTIVE: The objective of this study is to investigate the expressions of NMU and NMUR1 in the tryptase  +  MCs and the peripheral blood leukocytes (PBLs) in human nasal mucosa with AR...
February 20, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38332587/the-surprising-effect-of-priming-on-snot-22-results
#7
JOURNAL ARTICLE
Ibtisam Mohammad, Taylor Stack, Meghan Norris, Sulgi Kim, Meredith Lamb, Brian D Thorp, Christine Klatt-Cromwell, Charles S Ebert, Adam J Kimple, Brent A Senior
BACKGROUND: Priming is a psychological phenomenon where subconscious cues in the environment impact our behavioral responses in certain situations. Well studied in the worlds of business, marketing, and even politics, it is unclear how the priming phenomenon impacts patient perception of their own disease state nor how they report that perception using tools like the Sinonasal Outcomes Test (SNOT-22), used to measure that perception in chronic rhinosinusitis. OBJECTIVE: To determine the impact of positive or negative priming on self-reported patient perception of their chronic rhinosinusitis disease using the SNOT-22 disease-specific quality of life instrument...
February 8, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38192070/microrna-125b-is-a-potential-predictor-of-surgical-outcomes-in-chronic-rhinosinusitis-with-nasal-polyps
#8
JOURNAL ARTICLE
Anda Gata, Daniel-Corneliu Leucuta, Liviuta Budisan, Lajos Raduly, Veronica E Trombitas, Ioana Berindan-Neagoe, Silviu Albu
BACKGROUND: Despite advances in surgical techniques, recurrence rates after endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP) remain high and difficult to predict. OBJECTIVE: This study aimed to evaluate the potential role of microRNA 125b (miR-125b) in predicting disease evolution following ESS. METHODS: We conducted a prospective study including patients undergoing first ESS for CRSwNP in our department between January 2020 and November 2021...
January 8, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38155492/treatment-management-and-otolaryngology-consultation-for-epistaxis-in-the-emergency-room-an-institutional-experience
#9
JOURNAL ARTICLE
Daniel Jacobs, Vickie J Wang, Janet R Chao, R Peter Manes, Yan H Lee
BACKGROUND: Epistaxis is a common reason for emergency department (ED) visits, accounting for approximately 1 of every 200 ED visits in the United States annually and up to one-third of all otolaryngology (ENT)-related ED encounters. OBJECTIVES: To detail reasons for ENT consultation for epistaxis in the ED, understand how consultation impacts patient care, assess follow-up patterns after emergency care, and study patient care after transfer or referral into the ED...
December 28, 2023: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38321778/-add-what-you-can-to-life
#10
EDITORIAL
Greg E Davis
No abstract text is available yet for this article.
March 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38225197/higher-risk-of-rheumatoid-arthritis-in-patients-with-chronic-rhinosinusitis-prospective-association-in-the-u-k-biobank-and-genetic-evidence-by-mendelian-randomization-analysis
#11
JOURNAL ARTICLE
Yimin Dong, Weizhong Ding, Kehan Song, Feng Li
BACKGROUND: Previous studies have shown that respiratory diseases are associated with an increased risk of rheumatoid arthritis (RA). However, whether there is a correlation between chronic rhinosinusitis (CRS) and RA is not known. Due to the high incidence of CRS, it remains to be clarified whether we should pay additional attention to RA risk in the huge population of CRS. METHODS: We used a 2-sample Mendelian randomization (MR) analysis to explore the causal effects of CRS on the incidence of RA...
March 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38055971/validation-of-minimal-clinically-important-difference-mcid-for-university-of-pennsylvania-smell-identification-test-upsit
#12
JOURNAL ARTICLE
Ashna Mahadev, Dorina Kallogjeri, Jay F Piccirillo
BACKGROUND: The University of Pennsylvania Smell Identification Test is widely used to measure change in olfactory function, but a minimal clinically important difference (MCID) has not been well-established. A study published in 1997 regarding patients with head trauma reported an MCID of 4 but did not detail the methods used in the calculation. OBJECTIVE: To validate the MCID for UPSIT in patients with postviral, sinusitis, and procedure-associated olfactory loss...
March 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38032249/you-do-not-rise-to-the-level-of-your-goals-you-fall-to-the-level-of-your-systems
#13
EDITORIAL
Ralph Abi Hachem
No abstract text is available yet for this article.
January 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/37908086/association-between-chronic-rhinosinusitis-and-reflux-diseases-in-adults-a-systematic-review-and-meta-analysis
#14
JOURNAL ARTICLE
Ahmad Aldajani, Fahad Alhussain, Tamer Mesallam, Mashal AbaAlkhail, Raed Alojayri, Hashem Bassam, Omar Alotaibi, Mohammed Alqahtani, Saad Alsaleh
BACKGROUND: Over the last few decades, reflux diseases, such as laryngopharyngeal reflux (LPR) and gastroesophageal reflux disease (GERD), have been identified as significant contributors to inflammatory upper aerodigestive tract diseases. Establishing a direct relationship between reflux disease and chronic rhinosinusitis (CRS) is challenging due to the high prevalence of both diseases and their potential for independent coexistence. OBJECTIVE: The purpose of this study is to review the existing literature and evaluate the evidence of an association between reflux diseases and CRS...
January 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/37817645/association-between-immune-related-disease-and-allergic-rhinitis-a-two-sample-mendelian-randomization-study
#15
JOURNAL ARTICLE
Jinming Zhao, Mengmeng Zhang, Zufei Li
BACKGROUND: Immune-related diseases can interact with each other, and growing evidence suggests that these diseases are associated with allergic rhinitis (AR). However, it is unclear whether previously observed associations reflect causal relationships. OBJECTIVE: This study estimated the genetic association between various immune-related diseases and AR using two-sample Mendelian randomization (MR). METHODS: Eight immune-related diseases were selected as exposure factors, and AR was selected as the outcome...
January 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/37750177/long-term-efficacy-of-dupilumab-for-eosinophilic-chronic-rhinosinusitis
#16
JOURNAL ARTICLE
Yasuhiro Tsunemi, Tsuguhisa Nakayama, Takashi Kashiwagi, Makoto Akutsu, Shota Saito, Shinichi Haruna
BACKGROUND: Eosinophilic chronic rhinosinusitis (eCRS) is a type 2 inflammatory disease that frequently recurs after surgery. In recent years, dupilumab has been available for the treatment of refractory chronic rhinosinusitis since 2020 in Japan. Although there are some reports of its usefulness, there are not enough reports of its clinical efficacy for longer than 1 year, especially for olfactory recovery. METHODS: Twenty patients with eCRS who had recurrence after surgery and had been receiving dupilumab were enrolled retrospectively...
January 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38105576/the-efficacy-of-sodium-phytate-as-a-natural-chelating-agent-in-reducing-elevated-calcium-levels-in-nasal-mucus-among-individuals-experiencing-olfactory-dysfunction-following-covid-19-a-prospective-randomized-double-controlled-clinical-trial
#17
JOURNAL ARTICLE
Abdullah H Altemani, Mansuor A Alanazi, Assem H Altemani, Adnan Alharbi, Saud Alsahali, Nawaf M Alotaib, Mohamed H Abdelazim
BACKGROUND: COVID-19 has been associated with olfactory disturbances in many infected patients. The increase in calcium levels in nasal secretions plays an essential role in the olfactory process with a desensitizing effect on olfactory receptor neurons and negative effects on odor transmission. Calcium chelating agents have the ability to bind calcium in nasal mucus and prevent the negative effects associated with calcium increase. OBJECTIVES: The aim of this work is to demonstrate the intra-nasal topical application of sodium phytate, an environmentally friendly, non-harmful calcium chelating agent, to reduce the adverse effects of calcium on olfactory function and improve olfactory dysfunction according to COVID-19...
December 17, 2023: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38093177/genetic-association-of-allergic-rhinitis-with-sleep-and-neuropsychological-disorders-a-mendelian-randomization-study
#18
JOURNAL ARTICLE
Chenxi Lin, Jia Li, Ye Deng, Xiongwen Li, Xiaofeng Wang, Jingcheng Lu
BACKGROUND: The genetic association of allergic rhinitis (AR) with other physiological systems throughout the human body remains unknown. OBJECTIVE: The aim of this Mendelian randomization (MR) study was to explore the association of this respiratory disorder with multiple common sleep and neuropsychological disorders at the genetic level. METHODS: Summary data for total AR and pollen AR were collected from the most updated FinnGen genome-wide association studies involving more than 340 000 European subjects...
December 13, 2023: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/37994027/the-effect-of-rosmarinic-acid-on-wound-healing-of-nasal-mucosa-in-the-rats
#19
JOURNAL ARTICLE
Arzu Erdal, Doğukan Özdemir, Şule Özdemir, Mustafa Bakırtaş, İbrahim Ağrı
BACKGROUND: The nose can be damaged by environmental pollutants and foreign bodies, as well as a result of trauma, infection or surgical interventions. Proper healing of the damaged nasal mucosa is important for health. OBJECTIVE: There is no study in the literature investigating the effects of rosmarinic acid on mucosal healing. The aim of this study was to investigate the effect of rosmarinic acid on nasal mucosal healing. METHODS: 21 male, adult Spraque Dawley albino rats were divided into three groups as the control group, the local treatment group in which rosmarinic acid was applied locally to the nasal mucosa, and the systemic treatment group in which rosmarinic acid was injected intraperitoneally...
November 22, 2023: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/37936308/the-impact-of-the-nasal-mucosal-flap-on-tissue-remodeling-after-sinus-bone-drilling-in-rabbit-models
#20
JOURNAL ARTICLE
Cao Lv, Cheng Li, Jing Qu, Yi Dong, Zhenxiao Huang, Yan Sun, Shunjiu Cui, Qian Huang, Bin Wang, Mingrui Huo, Bing Zhou
BACKGROUND: Frontal sinus surgery remained a challenge of restenosis or obliteration of the drainage pathway caused by the scarring and neo-osteogenesis after mucosal stripping and bone drill-out. The pedicled or free nasal mucosal flap is typically used to repair the exposed bone surface to avoid or reduce recurrence. OBJECTIVE: This study aimed to explore the histopathological mechanism of mucosal flaps repairing bare bone after mucosal resection and bone drill-out in the rabbit model...
November 7, 2023: American Journal of Rhinology & Allergy
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