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Circulation. Cardiovascular Quality and Outcomes

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https://read.qxmd.com/read/30950652/racial-ethnic-and-socioeconomic-inequities-in-the-prescription-of-direct-oral-anticoagulants-in-patients-with-venous-thromboembolism-in-the-united-states
#1
Ashwin S Nathan, Zhi Geng, Elias J Dayoub, Sameed Ahmed M Khatana, Lauren A Eberly, Taisei Kobayashi, Steven C Pugliese, Srinath Adusumalli, Jay Giri, Peter W Groeneveld
BACKGROUND: Beginning in 2012, direct oral anticoagulants (DOACs) were approved for treatment and prevention of venous thromboembolism. Prior investigations have demonstrated slow rates of adoption of novel therapeutics for black patients. We assessed the association of racial/ethnic and socioeconomic factors with DOAC use among commercially insured venous thromboembolism patients. METHODS AND RESULTS: We performed a retrospective cohort analysis of adult patients with an incident diagnosis of venous thromboembolism between January 2010 and December 2016 using OptumInsight's Clinformatics Data Mart...
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30950651/cardiovascular-disease-risk-factors-and-myocardial-infarction-in-the-transgender-population
#2
Talal Alzahrani, Tran Nguyen, Angela Ryan, Ahmad Dwairy, James McCaffrey, Raza Yunus, Joseph Forgione, Joseph Krepp, Christian Nagy, Ramesh Mazhari, Jonathan Reiner
BACKGROUND: As of 2016, ≈1.4 million people in the United States identify as transgender. Despite their growing number and increasing specific medical needs, there has been a lack of research on cardiovascular disease (CVD) and CVD risk factors in this population. Recent studies have reported that the transgender population had a significantly higher rate of CVD risk factors without a significant increase in overall CVD morbidity and mortality. These studies are limited by their small sample sizes and their predominant focus on younger transgender populations...
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30950650/association-of-long-term-exposure-to-particulate-matter-and-ozone-with-health-status-and-mortality-in-patients-after-myocardial-infarction
#3
Ali O Malik, Philip G Jones, Paul S Chan, Poghni A Peri-Okonny, Vittal Hejjaji, John A Spertus
BACKGROUND: Long-term exposure to particulate matter <2.5 µm in diameter (PM2.5 ) and ozone has been associated with the development and progression of cardiovascular disease and, in the case of PM2.5 , higher cardiovascular mortality. Whether exposure to PM2.5 and ozone is associated with patients' health status and quality of life is unknown. We used data from 2 prospective myocardial infarction (MI) registries to assess the relationship between long-term PM2.5 and ozone exposure with health status outcomes 1 year after an MI...
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30950649/invisible-gender-in-medical-research
#4
EDITORIAL
Paul S Chan
No abstract text is available yet for this article.
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30939922/rationale-and-design-of-empower-a-pragmatic-randomized-trial-of-automated-hovering-in-patients-with-congestive-heart-failure
#5
Shivan J Mehta, Kevin G Volpp, David A Asch, Lee R Goldberg, Louise B Russell, Laurie A Norton, Lauren G Iannotte, Andrea B Troxel
BACKGROUND: Congestive heart failure is a major cause of morbidity, mortality, and cost. Disease management programs have shown promise but lack firm evidence of effectiveness and scalability. We describe the motivation, design, and planned analyses of EMPOWER (Electronic Monitoring of Patients Offers Ways to Enhance Recovery), a randomized clinical trial of an innovative intervention incorporating behavioral economic principles with remote monitoring technology embedded within a healthcare system...
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30917685/tackling-the-burden-of-cardiovascular-diseases-in-india
#6
Ahmad A Abdul-Aziz, Prabha Desikan, Dorairaj Prabhakaran, Lee F Schroeder
No abstract text is available yet for this article.
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30909730/ignored-in-plain-sight
#7
EDITORIAL
Michelle A Albert
No abstract text is available yet for this article.
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30909729/stress-resilience-and-cardiovascular-disease-risk-among-black-women
#8
Ashley S Felix, Amy Lehman, Timiya S Nolan, Shawnita Sealy-Jefferson, Khadijah Breathett, Darryl B Hood, Daniel Addison, Cindy M Anderson, Crystal W Cené, Barbara J Warren, Rebecca D Jackson, Karen Patricia Williams
BACKGROUND: Empirical data on the link between stress and cardiovascular disease (CVD) risk among black women is limited. We examined associations of stressful life events and social strain with incident CVD among black women and tested for effect modification by resilience. METHODS AND RESULTS: Our analysis included 10 785 black women enrolled in the Women's Health Initiative Observational Study and Clinical Trials cohort. Participants were followed for CVD for up to 23 years (mean, 12...
April 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30879326/sex-specific-determinants-of-outcomes-after-transcatheter-aortic-valve-replacement
#9
Michele Pighi, Nicolo Piazza, Giuseppe Martucci, Kevin Lachapelle, Louis P Perrault, Anita W Asgar, Sandra Lauck, John G Webb, Jeffrey J Popma, Dae H Kim, Thierry Lefèvre, Marino Labinaz, Andre Lamy, Mark D Peterson, Rakesh C Arora, Nicolas Noiseux, Amanda Trnkus, Jonathan Afilalo
Background Women account for a large proportion of patients treated with transcatheter aortic valve replacement, yet there remain conflicting reports about the effect of sex on outcomes. Moreover, the sex-specific prevalence and prognostic impact of frailty has not been systematically studied in the context of transcatheter aortic valve replacement. Methods and Results A preplanned analysis of the FRAILTY-AVR study (Frailty Aortic Valve Replacement) was performed to analyze the determinants of outcomes in older women and men undergoing transcatheter aortic valve replacement...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30879325/do-not-resuscitate-status-and-risk-standardized-mortality-and-readmission-rates-following-acute-myocardial-infarction
#10
Jeffrey Bruckel, Brahmajee K Nallamothu, Frederick Ling, Erik H Howell, Charles J Lowenstein, Sabu Thomas, Steven M Bradley, Anuj Mehta, Allan J Walkey
Background Important administrative-based measures of hospital quality, including those used by Centers for Medicare and Medicaid Services, may not adequately account for patient illness and social factors that vary between hospitals and can strongly affect outcomes. Do-not-resuscitate (DNR) order on admission (within the first 24 hours) is one such factor that may reflect higher preadmission illness burden as well as patients' desire for less-intense therapeutic interventions and has been shown to vary widely between hospitals...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30879324/epidemiology-of-shock-in-contemporary-cardiac-intensive-care-units
#11
David D Berg, Erin A Bohula, Sean van Diepen, Jason N Katz, Carlos L Alviar, Vivian M Baird-Zars, Christopher F Barnett, Gregory W Barsness, James A Burke, Paul C Cremer, Jennifer Cruz, Lori B Daniels, Andrew P DeFilippis, Affan Haleem, Steven M Hollenberg, James M Horowitz, Norma Keller, Michael C Kontos, Patrick R Lawler, Venu Menon, Thomas S Metkus, Jason Ng, Ryan Orgel, Christopher B Overgaard, Jeong-Gun Park, Nicholas Phreaner, Robert O Roswell, Steven P Schulman, R Jeffrey Snell, Michael A Solomon, Bradley Ternus, Wayne Tymchak, Fnu Vikram, David A Morrow
Background Clinical investigations of shock in cardiac intensive care units (CICUs) have primarily focused on acute myocardial infarction (AMI) complicated by cardiogenic shock (AMICS). Few studies have evaluated the full spectrum of shock in contemporary CICUs. Methods and Results The Critical Care Cardiology Trials Network is a multicenter network of advanced CICUs in North America. Anytime between September 2017 and September 2018, each center (n=16) contributed a 2-month snap-shot of all consecutive medical admissions to the CICU...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30871376/aiming-for-perfection
#12
EDITORIAL
Samuel M Kim, Dmitriy N Feldman
No abstract text is available yet for this article.
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30871375/trends-in-performance-and-opportunities-for-improvement-on-a-composite-measure-of-acute-myocardial-infarction-care
#13
Nihar R Desai, Jacob A Udell, Yongfei Wang, Erica S Spatz, Kumar Dharmarajan, Tariq Ahmad, Howard M Julien, Amarnath Annapureddy, Abhinav Goyal, James A de Lemos, Frederick A Masoudi, Deepak L Bhatt, Karl E Minges, Harlan M Krumholz, Jeptha P Curtis
Background Despite improvements on individual process of care measures for acute myocardial infarction (AMI), little is known about performance on a composite measure of AMI care that assesses the delivery of many components of high-quality AMI care. We sought to examine trends in patient- and hospital-level performance on a composite defect-free care measure, identify disparities in the performance across sociodemographic groups, and identify opportunities to further improve quality and outcomes. Methods and Results We calculated the proportion of patients in the National Cardiovascular Data Registry-Acute Coronary Treatment and Intervention Outcomes Network Registry-Get With The Guidelines (now known as the Chest Pain - Myocardial Infarction Registry) between January 1, 2010, and December 31, 2017, receiving defect-free AMI care including guideline-recommended pharmacotherapy, timely provision of medical and reperfusion therapy, assessment of ventricular function, referral to cardiac rehabilitation, and smoking cessation counseling for patients with AMI...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30871374/upcoding-of-clinical-information-to-meet-appropriate-use-criteria-for-percutaneous-coronary-intervention
#14
Christopher A Rajkumar, William M Suh, Darrel P Francis
No abstract text is available yet for this article.
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30871373/policing-or-learning
#15
EDITORIAL
Sunil V Rao, Dennis T Ko, Brahmajee K Nallamothu
No abstract text is available yet for this article.
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30871337/association-between-hospital-recognition-for-resuscitation-guideline-adherence-and-rates-of-survival-for-in-hospital-cardiac-arrest
#16
Rohan Khera, Yuanyuan Tang, Mark S Link, Harlan M Krumholz, Saket Girotra, Paul S Chan
Background Hospitals participating in the national Get With The Guidelines-Resuscitation registry receive an award for high rates of adherence to quality metrics for in-hospital cardiac arrest. We sought to evaluate whether awards based on these quality metrics can be considered a proxy for performance on cardiac arrest survival. Methods and Results Among 195 hospitals with continuous participation in Get With The Guidelines-Resuscitation between 2012 and 2015, we identified 78 that received an award (Gold or Silver) for ≥85% compliance for all 4 metrics for in-hospital cardiac arrest-time to chest compressions, ≤1 minute; time to defibrillation, ≤2 minutes; device confirmation of endotracheal tube placement; and a monitored/witnessed arrest-for at least 12 consecutive months during 2014 to 2015...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30859852/disability-adjusted-life-years-following-adult-out-of-hospital-cardiac-arrest-in-the-united-states
#17
Ryan A Coute, Brian H Nathanson, Ashish R Panchal, Michael C Kurz, Nathan L Haas, Bryan McNally, Robert W Neumar, Timothy J Mader
Background Disability-adjusted life years (DALY) are a common public health metric used to consistently estimate and compare health loss because of both fatal and nonfatal disease burden. The annual number of DALY because of adult out-of-hospital cardiac arrest (OHCA) in the United States is unknown. Our objective was to estimate the DALY after adult nontraumatic, emergency medical services-treated OHCA, and to compare OHCA DALY to other leading causes of death and disability in the US. Methods and Results The DALY were calculated as the sum of years of life lost and years lived with disability...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30857413/detecting-anomalies-among-practice-sites-within-multicenter-trials
#18
Seth A Berkowitz, Kara E Rudolph, Sanjay Basu
BACKGROUND: Recent multisite trials reveal striking heterogeneities in results between trial sites. These may be because of population differences indicating different treatment benefits among different types of participants or site anomalies, such as failures to adhere to study protocols that could negatively affect study validity. We sought to determine whether a new data analysis strategy-transportability methods-could suggest site anomalies not readily identified through standard methods...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30857412/predicting-future-cardiovascular-events-in-patients-with-peripheral-artery-disease-using-electronic-health-record-data
#19
Elsie Gyang Ross, Kenneth Jung, Joel T Dudley, Li Li, Nicholas J Leeper, Nigam H Shah
BACKGROUND: Patients with peripheral artery disease (PAD) are at risk of major adverse cardiac and cerebrovascular events. There are no readily available risk scores that can accurately identify which patients are most likely to sustain an event, making it difficult to identify those who might benefit from more aggressive intervention. Thus, we aimed to develop a novel predictive model-using machine learning methods on electronic health record data-to identify which PAD patients are most likely to develop major adverse cardiac and cerebrovascular events...
March 2019: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/30857411/reducing-acute-kidney-injury-and-costs-of-percutaneous-coronary-intervention-by-patient-centered-evidence-based-contrast-use
#20
Amit P Amin, Patricia Crimmins-Reda, Samantha Miller, Brandon Rahn, Mary Caruso, Meghan Funk, Andrew Pierce, Howard I Kurz, John M Lasala, Alan Zajarias, Richard G Bach, Marc A Sintek, Nathan Frogge, Sudhir Jain, Hemant Kulkarni, Jasvindar Singh
No abstract text is available yet for this article.
March 2019: Circulation. Cardiovascular Quality and Outcomes
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