Journals Journal of Infection and Publi...

Journal of Infection and Public Health
Zhaohui Su, Barry L Bentley, Dean McDonnell, Ali Cheshmehzangi, Junaid Ahmad, Sabina Šegalo, Claudimar Pereira da Veiga, Yu-Tao Xiang
BACKGROUND: When it comes to pandemic response, preparation can be the key. Between 2020 and 2024, the fast-paced development of COVID-19-often compounded by pubic policies' failures to reflect the latest reality and the public's divergent reactions to the pandemic and the policies-means that society should prepare for exit strategies that can reflect the reality of the pandemic and the interests of the people. Yet oftentimes societies only have one exit strategy with limited scope. This paper investigates the dangers of having only one pandemic exit strategy for pandemics like COVID-19...
April 16, 2024: Journal of Infection and Public Health
Turky J Arbaein, Khulud K Alharbi, Afrah A Alfahmi, Khawlah O Alharthi, Sarah S Monshi, Ali M Alzahrani, Sanaa Alkabi
BACKGROUND: The global COVID-19 crisis has underscored the critical role of effective decision-making in healthcare systems. Saudi Arabia has shown resilience by implementing comprehensive testing, tracing, and vaccination measures. Given the unique cultural and religious characteristics of Makkah, specific challenges have prompted efforts to uncover local pandemic responses. This qualitative assessment aims to delineate the challenges faced by decision-makers during COVID-19 in Makkah and identify key interventions implemented by the Makkah healthcare cluster to manage and coordinate care...
April 16, 2024: Journal of Infection and Public Health
Giuseppina Caggiano, Simona Fioriti, Gianluca Morroni, Francesca Apollonio, Francesco Triggiano, Gloria D'Achille, Pasquale Stefanizzi, Lidia Dalfino, Luigi Ronga, Adriana Mosca, Eleonora Sparapano, Carmela De Carlo, Fabio Signorile, Salvatore Grasso, Francesco Barchiesi, Maria Teresa Montagna
BACKGROUND: Candidemia is the most common healthcare associated invasive fungal infection. Over the last few decades, candidemia caused by Candida species other than Candida albicans, particularly the Candida parapsilosis complex, has emerged worldwide. The aims of this study were: to analyze the genotypic and phenotypic characteristics of C. parapsilosis strains isolated from blood cultures and the environment in a hospital in southern Italy, to study the possible source of infection and to correlate the isolated strains...
April 12, 2024: Journal of Infection and Public Health
Syed Mohammed Basheeruddin Asdaq, Sultan Alshehri, Sarah Abdulrahman Alajlan, Fadah Hasan Hasino, Shatha Khalid Alhammad, Taraf Shati Al Anazi, Reham Mansour Alasfr, Munirah Fahad Al Otaibi
BACKGROUND: Disability is a serious health issue that can have a significant impact on both physical and mental health. This study attempted to investigate the relationship between depression, quality of life (QOL), and COVID-19 challenges faced by people with disabilities (PwD) from Saudi Arabia. METHODS: A structured interview questionnaire to measure QOL (WHOQOL-BREF) and depression (PHQ-9) was used to conduct a cross-sectional study among PwDs in Saudi Arabia...
April 10, 2024: Journal of Infection and Public Health
Álvaro Tamayo-Velasco, Rocío López-Herrero, Lara María Gómez-García, Laura Sánchez-de Prada, Gerardo Aguilar-Monserrate, Marta Martín-Fernández, Miguel Bardají-Carrillo, Alejandro Álvaro-Meca, Eduardo Tamayo, Salvador Resino, José Pablo Miramontes-González, María Jesús Peñarrubia-Ponce
BACKGROUND: COVID-19-associated pulmonary aspergillosis (CAPA) has emerged as a relatively common complication. Multiple studies described this relationship in critical patients, however its incidence and outcome in other risk groups such as immunosuppressed patients remains unknown. In this sense, we aimed to evaluate the rates and outcomes of CAPA in hematological patients and according to the different hematological malignances, comparing to invasive pulmonary aspergillosis (IPA) in non-COVID-19 ones...
April 10, 2024: Journal of Infection and Public Health
Bayan Dubaie, Abdulaziz Aldayel, Shehana Alwethinani, Raghad Alhuthil, Fatimah Alhamlan, Salem Alghamdi, Mohammed Alsuhaibani, Suliman Aljumaah, Ohoud AlYabes, Esam AlBanyan, Sami Al-Hajjar
BACKGROUND: The actual burden of the Omicron variants remains unclear. Therefore, this study aims to analyze the epidemiological and clinical features of Omicron-infected patients and investigate factors influencing hospital admission. METHODS: This retrospective single-center study included individuals with positive SARS-CoV-2 infection, specifically the Omicron variants (XBB, EG or JN), identified through real-time reverse-transcriptase polymerase chain reaction assays from January 2022 to December 2023...
April 6, 2024: Journal of Infection and Public Health
Yujin Kim, Green Kim, Gukhui Min, YoungMin Woo, Kyong Ran Peck, Jung Joo Hong, Sun Bean Kim
BACKGROUND: After the eradication of smallpox, there have been no specific public health measures for any Orthopoxviruses (OPXVs). Therefore, it is necessary to countermeasure OPXV infections after Mpox (formerly monkeypox) occurrences, such as the latest global outbreak in 2022-2023. This study aimed to provide crucial insights for the development of effective public health policy making against mpox in populations residing in regions where the virus is not prevalent. METHODS: This study used enzyme-linked immunosorbent assays (ELISA) to examine smallpox and mpox antibodies in Koreans with three different age groups...
April 5, 2024: Journal of Infection and Public Health
Ahmad A Alshehri, Ahmad Adebayo Irekeola
Alkhumra hemorrhagic fever virus (AHFV) has spread beyond the Middle East. However, the actual global prevalence of the virus is yet unknown. This systematic review and meta-analysis, thus, followed the standard reporting guidelines to provide comprehensive details on the prevalence of Alkhumra virus infection globally. The pooled prevalence of AHFV globally was estimated at 1.3% (95% CI: 0.3-6.3), with higher prevalence in humans (3.4%, 95% CI: 0.4-25.0) compared to animals (0.7%, 95% CI: 0.3-1.8). The prevalence in ticks and camels were 0...
April 4, 2024: Journal of Infection and Public Health
Zainab Khalid, Javed Muhammad, Hina Ali, Muhammad Suleman Rana, Muhammad Usman, Muhammad Masroor Alam, Riaz Ullah, Arif Ullah, Massab Umair, Ashfaq Ahmad, Muhammad Salman, Aamer Ikram, Amjad Khan, Ahmed Bari
BACKGROUND: Measles has been a significant public health concern in Pakistan, especially in the Khyber Pakhtunkhwa (KPK) province, where sporadic and silent epidemics continue to challenge existing control measures. This study aimed to estimate the prevalence and investigate the molecular epidemiology of the measles virus (MeV) in KPK and explore the vaccination status among the suspected individuals. METHODS: A cross-sectional study was conducted between February and October 2021...
March 29, 2024: Journal of Infection and Public Health
Ryo Kinoshita, Satoru Arai, Motoi Suzuki, Hiroshi Nishiura
BACKGROUND: Rubella remains a public health challenge in Japan, impeding the attainment of herd immunity. Despite vaccination efforts since 1976, persistent outbreaks reveal a susceptibility gap in male adults born before 1995. Seroepidemiological surveys are pivotal in evaluating population immunity and identifying at-risk groups. METHODS: This study aims to pinpoint high-risk areas for potential rubella outbreaks in Japan by merging seroepidemiological data from 2020 with population census information...
March 29, 2024: Journal of Infection and Public Health
Taweegrit Siripongboonsitti, Kriangkrai Tawinprai, Panisadee Avirutnan, Kunlakanya Jitobaom, Prasert Auewarakul
BACKGROUND: The efficacy of the viral clearance and clinical outcomes of favipiravir (FPV) in outpatients being treated for coronavirus disease 2019 (COVID-19) is unclear. Ivermectin (IVM), niclosamide (NCL), and FPV demonstrated synergistic effects in vitro for exceed 78% inhibiting severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) replication. METHODS: A phase 2, open-label, 1:1, randomized, controlled trial was conducted on Thai patients with mild-to-moderate COVID-19 who received either combination FPV/IVM/NCL therapy or FPV alone to assess the rate of viral clearance among individuals with mild-to-moderate COVID-19...
March 29, 2024: Journal of Infection and Public Health
W Frank Peacock, Abhay Dhand, Nancy M Albert, Zainab Shahid, Alfred Luk, Kathleen Vollman, Reagan B Schoppelrey, Cynthia Cadwell, Sanjeet Dadwal, Alpesh N Amin, Francesca J Torriani
The current standard of stethoscope hygiene doesn't eliminate the transmission of harmful pathogens, including multi-drug resistant organisms (MDROs). In the era of the increasing prevalence of MDRO infections, the use of new systems providing touch free barriers may improve patient safety versus traditional stethoscope cleaning practices with chemical agents. Our purpose was to provide a narrative literature review regarding barriers as an improvement over the current standard of care for stethoscope hygiene...
March 28, 2024: Journal of Infection and Public Health
Cristina Merla, Marina Ramus, Angela Kuka, Irene Mileto, Stefano Gaiarsa, Amelia Di Comite, Marta Corbella, Antonio Piralla, Marina Liliana Lanave, Alba Muzzi, Stefano Ghirardello, Fausto Baldanti, Patrizia Cambieri
Newborns admitted to neonatal intensive care units (NICU) are at increased risk of health care-associated infections. Serratia marcescens represent the third most common pathogen in NICU outbreaks. Here we present an outbreak investigation performed using Whole Genome Sequencing (WGS) analyses and the control measures implemented to limit the spread of S. marcescens in the NICU of an Italian hospital. In February 2023 S. marcescens was isolated from six newborns, when in 2022 this pathogen was isolated only from two samples in the same ward...
March 28, 2024: Journal of Infection and Public Health
Yu-Shan Huang, Jia-Ling Yang, Jann-Tay Wang, Wang-Huei Sheng, Chia-Jui Yang, Yu-Chung Chuang, Shan-Chwen Chang
BACKGROUND: Carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a substantial healthcare challenge. This study assessed the in vitro efficacy of selected antibiotic combinations against CRKP infections. METHODS: Our research involved the evaluation of 40 clinical isolates of CRKP, with half expressing Klebsiella pneumoniae carbapenemase (KPC) and half producing Metallo-β-lactamase (MBL), two key enzymes contributing to carbapenem resistance. We determined the minimum inhibitory concentrations (MICs) of four antibiotics: eravacycline, tigecycline, polymyxin-B, and ceftazidime/avibactam...
March 27, 2024: Journal of Infection and Public Health
Muhammad Imran Nisar, Nadia Ansari, Mashal Amin, Farah Khalid, Shahira Shahid, Marvi Mahesar, Maryam Mansoor, Muhammad Farrukh Qazi, Aneeta Hotwani, Najeeb Rehman, Arslan Ashraf, Zahoor Ahmed, Ashfaque Ahmed, Arslan Memon, Fyezah Jehan
BACKGROUND: Households are considered ideal settings for studying the transmission dynamics of an infectious disease. METHODS: A prospective study was conducted, based on the World Health Organization FFX protocol from October 2020 to January,2021. Household contacts of laboratory-confirmed index cases were followed up for their symptomatic history, nasal swabs for RT-PCR,and blood samples for anti-SARS CoV-2 antibodies were collected at enrollment and days 7, 14 and 28...
March 27, 2024: Journal of Infection and Public Health
Fatou Samba Diouf, Maryam Tidjani Alou, Hubert Bassene, Sebastien Cortaredona, Georges Diatta, Didier Raoult, Cheikh Sokhna, Jean-Christophe Lagier
BACKGROUND: The surveillance of respiratory pathogens in rural areas of West Africa has, to date, largely been focussed on symptoms. In this prospective study conducted prior to the COVID-19 pandemic, we aimed to assess the asymptomatic prevalence of respiratory pathogen carriage in a group of individuals living in a rural area of Senegalese. METHODS: Longitudinal follow up was performed through monthly nasopharyngeal swabbing during the dry season and weekly swabbing during the rainy season...
March 26, 2024: Journal of Infection and Public Health
Torkel Engeness, Espen Henriksen
No abstract text is available yet for this article.
March 22, 2024: Journal of Infection and Public Health
Rabia Hayee, Mehwish Iqtedar, Norah A Albekairi, Abdulrahman Alshammari, Mauhammad Atif Makhdoom, Muhammad Islam, Nadeem Ahmed, Muhammad Fawad Rasool, Chen Li, Hamid Saeed
BACKGROUND: With the global increase in antibacterial resistance, the challenge faced by developing countries is to utilize the available antibiotics, alone or in combination, against resistant bacterial strains. We aimed to encapsulate the levofloxacin (LVX) into polymeric nanoparticles using biodegradable polymers i.e. Chitosan and PLGA, estimating their physicochemical characteristics followed by functional assessment as nanocarriers of levofloxacin against the different resistant strains of bacteria isolated from biological samples collected from tertiary care hospital in Lahore, Pakistan...
March 22, 2024: Journal of Infection and Public Health
Abdel Hadi Shmoury, Wael Hanna, Johnny Zakhour, Nada Kara Zahreddine, Souha S Kanj
BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) are the most common device-associated healthcare-acquired infections and pose a significant burden on patients and healthcare systems worldwide. However, there is a paucity of data on CAUTI epidemiology and microbiology in the Middle East and North Africa (MENA) region, including Lebanon. METHODS: This 14-year retrospective cohort study was conducted at a tertiary care center in Lebanon. It analyzed data on all adult patients diagnosed with CAUTI between January 2009 and December 2022 in intensive care units (ICUs) and between June 2011 and December 2022 in regular units...
March 22, 2024: Journal of Infection and Public Health
Sukbin Jang, Minji Jeon, Seok Jun Mun, Si-Ho Kim
BACKGROUND: Pyometra is a disease characterized by the collection of pus in the uterus. The clinical characteristics and etiology of pyometra have not been sufficiently described. In this study, we investigated the clinical characteristics, epidemiology, outcomes, and risk factors of septic shock in patients with pyometra. METHODS: Patients with pyometra admitted to one of four university-affiliated hospitals between January 2010 to August 2022 were enrolled. Pyometra cases associated with peripartum infection and surgical site infection were excluded...
March 20, 2024: Journal of Infection and Public Health
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