journal
https://read.qxmd.com/read/38464882/targeted-augmented-reality-guided-transperineal-prostate-biopsies-study-initial-experience
#1
JOURNAL ARTICLE
Shenthiuiyan Theivendrampillai, Bob Yang, Mark Little, Christopher Blick
BACKGROUND: Transperineal biopsy of magnetic resonance imaging (MRI)-detected prostate lesions is now the established technique used in prostate cancer (CaP) diagnostics. Virtual Surgery Intelligence (VSI) Holomedicine by Apoqlar (Hamburg, Germany) is a mixed reality (MR)/augmented reality (AR) software platform that runs on the HoloLens II system (Microsoft, Redford, USA). Multiparametric prostate MRI images were converted into 3D holograms and added into a MR space, enabling visualization of a 3D hologram and image-assisted prostate biopsy...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38434237/the-incidence-pathogenesis-and-management-of-non-clear-cell-renal-cell-carcinoma
#2
REVIEW
Priyanka Naik, Harshitha Dudipala, Yu-Wei Chen, Brent Rose, Aditya Bagrodia, Rana R McKay
Renal cell carcinoma (RCC) is the most common type of kidney cancer and is divided into two distinct subtypes, clear cell renal cell carcinoma (ccRCC) and non-clear cell renal cell carcinoma (nccRCC). Although many treatments exist for RCC, these are largely based on clinical trials performed in ccRCC and there are limited studies on the management of nccRCC. Non-clear cell RCC consists of multiple histological subtypes: papillary, chromophobe, translocation, medullary, collecting duct, unclassified, and other rare histologies...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38425504/carboplatin-in-metastatic-castration-resistant-prostate-cancer-patients-with-molecular-alterations-of-the-dna-damage-repair-pathway-the-pro-carbo-phase-ii-trial
#3
JOURNAL ARTICLE
Elodie Coquan, Nicolas Penel, Justine Lequesne, Raphaël Leman, Pernelle Lavaud, Zoé Neviere, Pierre-Emmanuel Brachet, Emeline Meriaux, Aurélien Carnot, Jérémy Boutrois, Marie Castera, Nicolas Goardon, Etienne Muller, Alexandra Leconte, Antoine Thiery-Vuillemin, Bénédicte Clarisse, Florence Joly
INTRODUCTION: DNA damage repair genes are altered in 20-35% of metastatic castration-resistant prostate cancer (mCRPC). Poly-ADP (Adénosine Diphosphate)-ribose polymerase inhibitors (PARPi) showed significant activity for these selected tumors, especially with homologous recombination repair (HRR) deficiency. These alterations could also predict platinum sensitivity. Although carboplatin was inconclusive in unselected mCRPC, the literature suggests an anti-tumoral activity in mCRPC with HHR gene alterations...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38405422/formation-of-vesicovaginal-fistula-after-modified-mcdonald-cerclage-placement-a-case-report-with-literature-review
#4
Deama AlGhamdi, Samera F AlBasri
Cervical cerclage is a common procedure employed to prevent preterm birth in women with cervical insufficiency. Complications such as injuries to the cervix and bladder, and premature membrane rupture are well-documented, while genitourinary fistulas are a rare occurrence. This article reports a rare case of vesicovaginal fistula (VVF) formation in a 27-year-old woman following the placement of a McDonald cervical cerclage. The patient presented with continuous watery vaginal leakage, which began during the last 2 months of her pregnancy...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38405421/is-suction-the-future-of-endourology-overview-from-eau-section-of-urolithiasis
#5
EDITORIAL
Victoria Jahrreiss, Carlotta Nedbal, Daniele Castellani, Vineet Gauhar, Christian Seitz, Guohua Zeng, Patrick Juliebø-Jones, Etienne Keller, Lazaros Tzelves, Rob Geraghty, Karan Rangarajan, Olivier Traxer, Joe Philip, Andreas Skolarikos, Panagiotis Kallidonis, Ewa Bres-Niewada, Bhaskar Somani
No abstract text is available yet for this article.
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38348129/the-impact-of-prognostic-group-classification-on-prostate-cancer-progression-in-intermediate-risk-patients-according-to-the-european-association-of-urology-system-results-in-479-patients-treated-with-robot-assisted-radical-prostatectomy-at-a-single-tertiary
#6
JOURNAL ARTICLE
Antonio Benito Porcaro, Alberto Bianchi, Andrea Panunzio, Sebastian Gallina, Alessandro Tafuri, Emanuele Serafin, Rossella Orlando, Giovanni Mazzucato, Stefano Vidiri, Damiano D'Aietti, Francesca Montanaro, Giulia Marafioti Patuzzo, Francesco Artoni, Alberto Baielli, Francesco Ditonno, Riccardo Rizzetto, Alessandro Veccia, Alessandra Gozzo, Vincenzo De Marco, Matteo Brunelli, Maria Angela Cerruto, Alessandro Antonelli
BACKGROUND: Treatment outcomes in intermediate-risk prostate cancer (PCa) may be impaired by adverse pathology misclassification including tumor upgrading and upstaging. Clinical predictors of disease progression need to be improved in this category of patients. OBJECTIVES: To identify PCa prognostic factors to define prognostic groups in intermediate-risk patients treated with robot-assisted radical prostatectomy (RARP). DESIGN: Data from 1143 patients undergoing RARP from January 2013 to October 2020 were collected: 901 subjects had available follow-up, of whom 479 were at intermediate risk...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38333072/oncological-outcomes-in-robot-assisted-radical-prostatectomy-the-value-of-psa-density-as-a-preoperative-predictive-factor
#7
JOURNAL ARTICLE
Roser Vives Dilme, Juan Gómez Rivas, Laura Fernández Hernández, Irene De la Parra Sánchez, Rafael Sánchez Del Hoyo, María Isabel Galante Romo, Enrique Redondo González, José Luis Senovilla Pérez, Lorena Fernández Montarroso, Jesús Moreno Sierra
BACKGROUND: Pretreatment assessment of patients diagnosed with localized prostate cancer (PCa) is essential for therapeutic decision-making. Currently available staging systems based on prostate-specific antigen (PSA), Gleason score, and clinical stage allow for determining the prognostic characteristics of these patients. Several studies have evaluated the preoperative use of prostate-specific antigen density (PSAD) as a prognostic factor for further risk stratification. To date, the role of PSAD in this setting is still an object of debate...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38333071/current-role-of-intraoperative-cell-salvage-techniques-in-the-management-of-renal-tumors-with-level-iii-and-iv-inferior-vena-cava-thrombus-extension
#8
JOURNAL ARTICLE
Cristian Surcel, Robert Dotzauer, Cristian Mirvald, Calin Popa, Cosmin Olariu, Catalin Baston, Mihai Harza, Constantin Gangu, Igor Tsaur, Ioanel Sinescu
BACKGROUND: En bloc removal of the kidney with tumor thrombus excision in a multidisciplinary team remains the standard treatment for renal cell carcinoma (RCC) with tumor thrombus extension. In order to minimize the hemodynamic impact of the surgical blood loss, intraoperative cell salvage (IOCS) techniques can decrease the need for allogeneic blood and prevent blood transfusion related complications. OBJECTIVE: In this article, we evaluated the safety of IOCS during radical nephrectomy with inferior vena cava thrombectomy under cardiopulmonary bypass with or without deep hypothermic circulatory arrest...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38328552/randomized-trial-of-mechanotherapy-for-the-treatment-of-stress-urinary-incontinence-in-women
#9
JOURNAL ARTICLE
Nissrine Nakib, Suzette Sutherland, Kevin Hallman, Marcus Mianulli, David R Boulware
BACKGROUND: Stress urinary incontinence (SUI) presents as unintentional urine leakage associated with activities. It significantly affects quality of life (QoL) and is the most common type of incontinence in women. Current treatment options, particularly non-surgical therapies, are lacking. OBJECTIVE: To assess the efficacy of mechanotherapy provided by the Flyte® intra-vaginal device during pelvic floor muscle training (PFMT). DESIGN: This was a randomized, controlled, double-blinded trial...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38250697/successful-bladder-sparing-partial-cystectomy-for-muscle-invasive-domal-urothelial-carcinoma-with-sarcomatoid-differentiation-a-case-report
#10
Mark Sultan, Ahmad Abdelaziz, Muhammed A Hammad, Juan R Martinez, Shady A Ibrahim, Mahra Nourbakhsh, Ramy F Youssef
High-grade (HG) urothelial carcinoma (UC) with variant histology has historically been managed conservatively. The presented case details a solitary lesion of muscle-invasive bladder cancer (MIBC) with sarcomatoid variant (SV) histology treated by partial cystectomy (PC) and adjuvant chemotherapy. A 71-year-old male with a 15-pack year smoking history presented after outside transurethral resection of bladder tumor (TURBT). Computerized tomography imaging was negative for pelvic lymphadenopathy, a 2 cm broad-based papillary tumor at the bladder dome was identified on office cystoscopy...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38223525/the-natural-history-of-benign-prostatic-hyperplasia-related-voiding-symptoms-following-penile-prosthesis-implantation
#11
JOURNAL ARTICLE
Raevti Bole, Prajit Khooblall, Petar Bajic
BACKGROUND: There is a rising prevalence of benign prostatic hyperplasia (BPH)-related urinary symptoms along with erectile dysfunction in the aging male population. Therefore, assessment of lower urinary tract symptoms (LUTS) is advised before penile prosthesis surgery with some men requiring preoperative transurethral surgical management to reduce the risk of post-procedure complications. However, less is known about the natural history of men with uncomplicated LUTS who do not require surgical management for BPH before penile prosthesis...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38205393/risk-and-benefits-of-penile-length-preservation-techniques-during-penile-prosthesis-implantation-a-systematic-review-by-the-young-academic-urologists-sexual-and-reproductive-health-working-group
#12
REVIEW
Marco Falcone, Mirko Preto, Afonso Ribeiro Morgado, Ioannis Sokolakis, Selçuk Sarıkaya, Marco Capece, Paolo Capogrosso, Celeste Manfredi, Georgios Tsampoukas, Giorgio Russo
BACKGROUND: Penile shortening, frequently resulting from end-stage Peyronie's disease (PD), has a negative impact on patients' sexual activity and overall quality of life, especially when accompanied by Erectile dysfunction (ED). Various surgical techniques have been described to manage concomitant ED and penile shortening through penile prosthesis (PP) implantation. OBJECTIVES: To evaluate the benefits and risks of different penile length preservation techniques during PP implantation...
2024: Therapeutic Advances in Urology
https://read.qxmd.com/read/38152349/surgical-treatment-of-pelvic-lipomatosis-a-systematic-review-of-231-cases
#13
REVIEW
Mancheng Xia, Shengwei Xiong, Zhihua Li, Shubo Fan, Yuke Chen, Liqun Zhou, Kai Zhang, Xuesong Li
BACKGROUND: Pelvic lipomatosis (PL) is a rare condition that is characterized by excessive growth of fat in the pelvic cavity. Studies have yet to systematically review surgical treatments for PL. OBJECTIVES: To provide a reference for selecting reasonable surgical treatments for PL patients according to previous literature on the surgical treatment of PL. DESIGN AND METHODS: We conducted this systematic review in accordance with the Preferred Reporting Items for a Systematic Review and Meta-Analysis (PRISMA) of Individual Participant Data guidelines...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/38146488/challenges-and-options-for-management-of-stones-in-anomalous-kidneys-a-review-of-current-literature
#14
REVIEW
Mudassir Wani, Ahmed Haider Abdalla Mohamed, Gareth Brown, Seshadri Sriprasad, Sanjeev Madaan
INTRODUCTION: Congenital anomalies of the kidney and urinary tract (CAKUT) represent a wide range of disorders that result from developmental abnormalities of the kidneys, urinary collecting tract, and lower urinary tract. There has been extensive development in approaches to the management of stones in normal kidneys with the advent of retrograde intra-renal surgeries (RIRS)/ureteroscopies, extracorporeal shock wave lithotripsy (ESWL) percutaneous nephrolithotomy (PCNL), and minimally invasive surgery (laparoscopy/robotics)...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/38130371/isolated-renal-and-urinary-tract-aspergillosis-a-systematic-review
#15
REVIEW
Felix Bongomin, Bethan Morgan, Bassey E Ekeng, Martha F Mushi, Winnie Kibone, Ronald Olum, David B Meya, Davidson H Hamer, David W Denning
BACKGROUND: Aspergillosis localized to the kidneys and the urinary tract is uncommon. We conducted a comprehensive systematic review to evaluate risk factors and clinical outcomes of patients with isolated renal and genito-urinary tract aspergillosis. METHODS: We systematically searched Medline, CINAHL, Embase, African Journal Online, Google Scholar, and the Cochrane Library, covering the period from inception to August 2023 using the key terms 'renal' OR 'kidney*' OR 'prostate' OR 'urinary bladder' OR 'urinary tract*AND 'aspergillosis' OR 'aspergillus' OR 'aspergilloma' OR 'mycetoma'...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/38090352/the-mini-jupette-technique-for-climacturia-a-systematic-review
#16
REVIEW
Mykoniatis Ioannis, Tsiakaras Stavros, Savvides Eliophotos, Langas Georgios, Anastasiadis Anastasios, Koenraad van Renterghem, Andrianne Robert
BACKGROUND: The leakage of urine during sexual arousal, known as climacturia, is an under-recognized clinical condition often overshadowed by erectile dysfunction in men who have undergone radical prostatectomy. OBJECTIVES: This study aims to determine and evaluate the role of the Mini-Jupette technique and its alternatives in the treatment of climacturia. DATA SOURCES AND METHODS: We conducted a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for systematic reviews...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/38046941/current-evidence-of-robotic-assisted-surgery-use-in-functional-reconstructive-and-neuro-urology
#17
REVIEW
Hermione Tsoi, Sameh F Elnasharty, Mehmet Gokhan Culha, Sabrina De Cillis, Cyrille Guillot-Tantay, François Hervé, Tanja Hüesch, Nicholas Raison, Véronique Phé, Nadir I Osman
The use of robot-assisted technology has been widely adopted in urological oncological surgery and its benefits have been well established. In recent years, robotic technology has also been used in several functional reconstructive and neuro-urology (FRNU) procedures. The aim of this review was to evaluate the current evidence in the use of robotic technology in the field of FRNU. We performed a PubMed-based literature search between July and August 2022. The keywords we included were 'robotic assisted', 'ureteric reimplantation', 'cystoplasty', 'ileal conduit', 'neobladder', 'sacrocolpopexy', 'colposuspension', 'artificial urinary sphincter', 'genitourinary fistula' and 'posterior urethral stenoses'...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/38046940/regional-variation-in-urinary-catheter-use-in-the-netherlands-from-2012-to-2021-a-population-based-cohort
#18
JOURNAL ARTICLE
Felice E E van Veen, Jeroen R Scheepe, Bertil F M Blok
OBJECTIVES: Our aim was to evaluate trends and regional differences in the use of indwelling and intermittent urinary catheters in the community setting in the Netherlands from 2012 to 2021. DESIGN AND METHODS: For this population-based cohort study, data on catheter use was collected from the Drug and Medical Devices Information System of the National Healthcare Institute of the Netherlands. This database contains information on the Dutch insured population, which was 100% of the total population in 2018...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/38033708/association-of-obesity-and-different-metabolic-status-with-prognosis-in-patients-with-bladder-cancer-a-retrospective-cohort-study
#19
JOURNAL ARTICLE
Yingchun Dong, Yiping Cheng, Honglin Guo, Jiaxing Sun, Junming Han, Fang Zhong, Qihang Li, Dawei Wang, Wenbin Chen, Xiude Fan, Jiajun Zhao
BACKGROUND AND OBJECTIVES: Patients with bladder cancer (BC) are at high risk for recurrence rates and readmission costs. However, the evidence about obesity and metabolic abnormalities on the BC prognosis was inconsistent. Our primary aim was to determine the impact of obesity and different metabolic status on the readmission risk in patients with BC. DESIGN AND METHODS: We identified 16,649 patients with BC using the 2018 Nationwide Readmissions Database who were hospitalized from January to June 2018 and followed for 180 days...
2023: Therapeutic Advances in Urology
https://read.qxmd.com/read/37953973/co-2-laser-therapy-for-management-of-stress-urinary-incontinence-in-women-a-systematic-review-and-meta-analysis
#20
REVIEW
Bandr Hafidh, Saeed Baradwan, Hassan M Latifah, Abdulrahim Gari, Hussein Sabban, Hanin Hassan Abduljabbar, Afaf Tawfiq, Ghaidaa Farouk Hakeem, Alya Alkaff, Nabigah Alzawawi, Radiah Iskandarani, Kausar Khurshid, Kausar Aisha Syed, Ammar Y Alkhiary, Ibtihal Abdulaziz Bukhari, Maha Al Baalharith, Ahmed Abu-Zaid
BACKGROUND: Carbon dioxide (CO2 ) laser therapy is an emerging treatment for women with stress urinary incontinence (SUI). OBJECTIVES: To examine the efficacy of CO2 laser therapy for management of SUI-related symptoms in women. DESIGN: A systematic review and meta-analysis of randomized controlled trials and cohort studies. DATA SOURCES AND METHODS: Four databases were screened until January 2023. All efficacy continuous endpoints were assessed via subtraction of the posttreatment from pretreatment values...
2023: Therapeutic Advances in Urology
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