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JOURNAL ARTICLE
Sven Baasen, Manuel Stern, Patricia Wischmann, Johanna Schremmer, Roberto Sansone, Maximilian Spieker, Georg Wolff, Florian Bönner, Christine Quast, Christian Heiss, Malte Kelm, Lucas Busch
BACKGROUND: Recent research indicates that there is a high prevalence of heart failure with preserved ejection fraction in patients with peripheral artery disease. We hypothesized that endovascular treatment (EVT) of flow-limiting peripheral stenosis improves left ventricular (LV) diastolic function. METHODS: Thirty patients with symptomatic peripheral artery disease and heart failure with preserved ejection fraction according to Heart Failure Association-preserved ejection fraction score who were scheduled for EVT or angiography were investigated at baseline, the day after EVT (n=25) or angiography (control, n=5), and at 4 months follow-up...
September 9, 2024: Circulation. Heart Failure
#2
EDITORIAL
Guillaume Goudot, Marie Denise Gerhard-Herman
No abstract text is available yet for this article.
September 9, 2024: Circulation. Heart Failure
#3
LETTER
João Almeida-Coelho, André M Leite-Moreira, Vasco Sequeira, Nazha Hamdani, André P Lourenço, Inês Falcão-Pires, Adelino F Leite-Moreira
No abstract text is available yet for this article.
September 6, 2024: Circulation. Heart Failure
#4
JOURNAL ARTICLE
Kieran F Docherty, Ruben Buendia Lopez, Folke Folkvaljon, Rudolf A De Boer, Martin R Cowie, Ann Hammarstedt, Dalane W Kitzman, Mikhail N Kosiborod, Anna Maria Langkilde, Barry Reicher, Michele Senni, Sanjiv J Shah, Subodh Verma, Scott D Solomon, John J V McMurray
Background: Wearable accelerometers can quantify the frequency and intensity of physical activity during everyday life and may provide complementary data to established functional outcome measures on the effect of heart failure therapies on functional limitations. Methods: In a voluntary substudy of the DETERMINE (Dapagliflozin EffecT on ExeRcise capacity using a 6-MINutE walk test in patients with HF) trials, patients wore a waist-worn tri-axial accelerometer for as long as possible (ideally for 24 hours/day for 7 days) at 3 points during the trial; between the screening visit and randomization (baseline data), and during weeks 8 and 14-16...
August 30, 2024: Circulation. Heart Failure
#5
JOURNAL ARTICLE
Henri Lu, Safia Chatur, Sahmin Lee, Riccardo M Inciardi, Martin Abanda, Finnian R Mc Causland, Arzu Kalayci, Kimia Karimi Taheri, Amil M Shah, Maja Cikes, Brian L Claggett, Narayana Prasad, Carolyn S P Lam, Eileen O'Meara, Xiaowen Wang, John J V McMurray, Marc A Pfeffer, Sheila M Hegde, Scott D Solomon, Hicham Skali
BACKGROUND: Renal dysfunction is common and associated with a poor prognosis in patients with heart failure. However, the association of cardiac structure and function with decline in kidney function in this population is unknown. We aimed to assess the association between individual measures of cardiac structure and function with changes in renal function and renal outcomes in patients with heart failure with preserved ejection fraction. METHODS: Patients enrolled in the PARAGON-HF (Prospective Comparison of Angiotensin Receptor-Neprilysin Inhibitor With Angiotensin-Receptor Blockers Global Outcomes in Heart Failure With Preserved Ejection Fraction) echocardiographic substudy were included...
August 30, 2024: Circulation. Heart Failure
#6
JOURNAL ARTICLE
Nael Aldweib, Payam Deghani, Craig S Broberg, Alexandra van Dissel, Ahmad Altibi, Joshua Wong, David Baker, Salil Gindi, Paul Khairy, Ahmad Alitibi, Alexander R Opotowsky, Sangeeta Shah, Anthony Magalski, Jonathan Cramer, Robert M Kauling, Mikael Dellborg, Eric V Krieger, Elizabeth Yeung, Jolien Roos-Hesselink, Jamil Aboulhosn, Jeremy Nicolarsen, Luke Masha, Pastora Gallego, David S Celermajer, Joseph Kay, Isabelle Vonder Muhll, Susan M Jameson, Clare O'Donnell, Flavia Fusco, Anitha S John, Conrad Macon, Petra Antonova, Timothy Cotts, Berardo Sarubbi, Fred Rodriguez, Christopher DeZorzi, Pavithra S Jayadeva, Marissa Kuo, Shelby Kutty, Tripti Gupta, Luke J Burchill, Carla P Rodriguez Monserrate, Adam M Lubert, Jasmine Grewal, Stephen Pylypchuk, Michael Belkin, William M Wilson
BACKGROUND: Patients with transposition of the great arteries (TGA) and systemic right ventricle often confront significant adverse cardiac events. The prognostic significance of invasive hemodynamic parameters in this context remains uncertain. Our hypothesis is that the aortic pulsatility index and hemodynamic profiling utilizing invasive measures provide prognostic insights for patients with TGA and a systemic right ventricle. METHODS: This retrospective multicenter cohort study encompasses adults with TGA and a systemic right ventricle who underwent cardiac catheterization...
August 29, 2024: Circulation. Heart Failure
#7
JOURNAL ARTICLE
Christopher R deFilippi, Palak Shah, Sanjiv J Shah, Wendimagegn Alemayehu, Carolyn S P Lam, Javed Butler, Lothar Roessig, Christopher M O'Connor, Cynthia M Westerhout, Paul W Armstrong
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that may emerge from overlapping systemic processes associated with comorbidities. We assessed whether unique clusters of circulating proteins are associated with specific clinical characteristics and functional status at baseline and follow-up in a well-phenotyped cohort of patients with HFpEF. METHODS: We evaluated 368 proteins associated with cardiovascular disease and inflammation in prerandomization blood samples from 763 VITALITY-HFpEF (Vericiguat to Improve Physical Functioning in Daily Living Activities of Patients With HFpEF) participants who had a left ventricular ejection fraction ≥45% and a heart failure decompensation event within 6 months...
August 29, 2024: Circulation. Heart Failure
#8
JOURNAL ARTICLE
Christos P Kyriakopoulos, Konstantinos Sideris, Iosif Taleb, Eleni Maneta, Rana Hamouche, Eleni Tseliou, Chong Zhang, Angela P Presson, Elizabeth Dranow, Kevin S Shah, Tara L Jones, James C Fang, Josef Stehlik, Craig H Selzman, Matthew L Goodwin, Joseph E Tonna, Thomas C Hanff, Stavros G Drakos
BACKGROUND: Cardiogenic shock (CS) can stem from multiple causes and portends poor prognosis. Prior studies have focused on acute myocardial infarction-CS; however, acute decompensated heart failure (ADHF)-CS accounts for most cases. We studied patients suffering ADHF-CS to identify clinical factors, early in their trajectory, associated with a higher probability of successful outcomes. METHODS: Consecutive patients with CS were evaluated (N=1162). We studied patients who developed ADHF-CS at our hospital (N=562)...
August 29, 2024: Circulation. Heart Failure
#9
EDITORIAL
Janet Wittes
No abstract text is available yet for this article.
August 28, 2024: Circulation. Heart Failure
#10
JOURNAL ARTICLE
Roger Winters, Alex Grubb, Ramon Eldermire, Erin McGuinn, Natasha Altman, William K Cornwell
No abstract text is available yet for this article.
August 28, 2024: Circulation. Heart Failure
#11
LETTER
Zhehao Dai, Toshiyuki Ko, Shunsuke Inoue, Seitaro Nomura, Kanna Fujita, Kenji Onoue, Yuki Kuramoto, Yoshihiro Asano, Manami Katoh, Shintaro Yamada, Mikako Katagiri, Bo Zhang, Takanobu Yamada, Tuolisi Heryed, Kosuke Sawami, Takahiro Jimba, Nanase Hori, Masayuki Kubota, Masamichi Ito, Eisuke Amiya, Masaru Hatano, Norifumi Takeda, Hiroyuki Morita, Yoshihiko Saito, Norihiko Takeda, Issei Komuro
No abstract text is available yet for this article.
August 28, 2024: Circulation. Heart Failure
#12
JOURNAL ARTICLE
Minjae Yoon, Wonse Kim, Woong Kook, Jin Joo Park, Barry Greenberg
BACKGROUND: The PARAGON-HF study (Prospective Comparison of ARNI With ARB Global Outcomes in Heart Failure With Preserved Ejection Fraction) investigated the effect of sacubitril-valsartan in heart failure (HF) with preserved ejection fraction. The results, which were analyzed using conventional statistical methods, did not find a significant reduction in the primary composite end point of cardiovascular death and total hospitalization for HF. Recent clinical trials used win ratio statistics that enable the incorporation of multiple outcome aspects into the primary end point and can detect positive outcomes with fewer patients...
August 28, 2024: Circulation. Heart Failure
#13
LETTER
Raziye Ecem Akdogan, Daniel Silverman, Michael Rofael, Sheng Fu, Elie Kozaily, Jessica Atkins, Gregory R Jackson, Chakradhari Inampudi, Jan M Griffin, Vishal N Rao, Mathew J Gregoski, Jennifer M Hajj, Jeffrey R Winterfield, Arman Kilic, Brian A Houston, Ryan J Tedford, Anthony P Carnicelli
No abstract text is available yet for this article.
August 22, 2024: Circulation. Heart Failure
#14
JOURNAL ARTICLE
Jef Van den Eynde, Pieter Martens, Jeroen Dauw, Petra Nijst, Evelyne Meekers, Jozine M Ter Maaten, Kevin Damman, Gerasimos Filippatos, Johan Lassus, Alexandre Mebazaa, Frank Ruschitzka, Matthias Dupont, Wilfried Mullens, Frederik H Verbrugge
BACKGROUND: Chloride plays a crucial role in renal salt sensing. This study investigates whether serum chloride is associated with clinical outcomes and decongestive response to acetazolamide in patients with acute decompensated heart failure. METHODS: This post hoc analysis includes all 519 patients from the ADVOR trial (Acetazolamide in Decompensated Heart Failure With Volume Overload), randomized to intravenous acetazolamide or matching placebo on top of intravenous loop diuretics...
August 22, 2024: Circulation. Heart Failure
#15
LETTER
Emanuele Monda, Giuseppe Limongelli
No abstract text is available yet for this article.
August 20, 2024: Circulation. Heart Failure
#16
LETTER
Koshiro Kanaoka, Kenji Onoue, Yoshihiko Saito
No abstract text is available yet for this article.
August 20, 2024: Circulation. Heart Failure
#17
JOURNAL ARTICLE
Arsalan Hamid, Wondwosen K Yimer, Adebamike A Oshunbade, Muhammad Shahzeb Khan, Daisuke Kamimura, Rodney K Kipchumba, Ambarish Pandey, Donald Clark Iii, Robert J Mentz, Ervin R Fox, Jarett D Berry, R Brandon Stacey, Amil Shah, Adolfo Correa, Salim S Virani, Javed Butler, Michael E Hall
BACKGROUND: Increased hsCRP (high-sensitivity C-reactive protein), a marker of inflammation, is associated with incident cardiovascular events. We aim to determine whether the baseline or trajectory of hsCRP levels over time predicts incident heart failure (HF) hospitalization. METHODS: JHS (Jackson Heart Study) participants' (n=3920 Black adults) hsCRP levels were measured over 3 visits (from 2000 to 2013). We assessed the association of hsCRP at baseline (visit 1) with incident HF hospitalization using Cox proportional hazards models...
August 9, 2024: Circulation. Heart Failure
#18
JOURNAL ARTICLE
W H Wilson Tang, Rozenn N Lemaitre, Paul N Jensen, Meng Wang, Zeneng Wang, Xinmin S Li, Ina Nemet, Yujin Lee, Heidi T M Lai, Marcia C de Oliveira Otto, Amanda M Fretts, Nona Sotoodehnia, Joseph A DiDonato, Fredrik Bäckhed, Bruce M Psaty, David S Siscovick, Matthew J Budoff, Dariush Mozaffarian, Stanley L Hazen
BACKGROUND: Growing evidence indicates that trimethylamine N -oxide, a gut microbial metabolite of dietary choline and carnitine, promotes both cardiovascular disease and chronic kidney disease risk. It remains unclear how circulating concentrations of trimethylamine N -oxide and its related dietary and gut microbe-derived metabolites (choline, betaine, carnitine, γ-butyrobetaine, and crotonobetaine) affect incident heart failure (HF). METHODS: We evaluated 11 768 participants from the Cardiovascular Health Study and the Multi-Ethnic Study of Atherosclerosis with serial measures of metabolites...
August 9, 2024: Circulation. Heart Failure
#19
JOURNAL ARTICLE
Signe Glargaard, Tania Deis, Annemette G Abild-Nielsen, Alexander Stark, Jakob H Thomsen, Søren L Kristensen, Kasper Rossing, Finn Gustafsson, Jens Jakob Thune
BACKGROUND: Pleural effusion is present in 50% to 80% of patients with acute heart failure, depending on image modality. We aim to describe the association between the presence and size of pleural effusion and central hemodynamics, including pulmonary capillary wedge pressure (PCWP) in an advanced heart failure population. METHODS: An observational, cross-sectional study in a cohort of patients with advanced heart failure (left ventricular ejection fraction ≤45%) who underwent right heart catheterization at The Department of Cardiology at Copenhagen University Hospital, Rigshospitalet, Denmark, between January 1, 2002 and October 31, 2020...
August 6, 2024: Circulation. Heart Failure
#20
EDITORIAL
Raymond C Parrish, Kai E Swenson
No abstract text is available yet for this article.
August 6, 2024: Circulation. Heart Failure
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