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Tuberculosis and Respiratory Diseases

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https://read.qxmd.com/read/30574692/is-cross-reactivity-with-nontuberculous-mycobacteria-a-systematic-problem-in-the-xpert-mtb-rif-assay
#1
Hee Jae Huh, Dong Joon Song, Chang Seok Ki, Nam Yong Lee
No abstract text is available yet for this article.
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30574691/high-flow-nasal-cannula-oxygen-delivery-during-bronchoalveolar-lavage-a-question-of-methodology-influence
#2
Subrata Kumar Singha, Antonio M Esquinas
No abstract text is available yet for this article.
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30574690/expression-of-muscarinic-receptors-and-the-effect-of-tiotropium-bromide-in-aged-mouse-model-of-chronic-asthma
#3
Ji Young Kang, In Kyoung Kim, Jung Hur, Seok Chan Kim, Sook Young Lee, Soon Seog Kwon, Young Kyoon Kim
BACKGROUND: Efficacy and safety of tiotropium bromide, a muscarinic receptor antagonist, in treatment of asthma have been reported. However, its effect on airway remodeling in chronic asthma of the elderly has not been clearly verified. The objective of this study was to investigate the effect of tiotropium and expression of muscarinic receptors as its related mechanism in an aged mouse model of chronic asthma with airway remodeling. METHODS: BALB/c female mice age 6 weeks, 9 and 15 months were sensitized and challenged with ovalbumin (OVA) for three months...
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30574689/clinical-phenotype-of-a-first-unprovoked-acute-pulmonary-embolism-associated-with-antiphospholipid-antibody-syndrome
#4
Yong Sub Na, Seongsoo Jang, Seokchan Hong, Yeon Mok Oh, Sang Do Lee, Jae Seung Lee
BACKGROUND: Antiphospholipid antibody syndrome (APS), an important cause of acquired thrombophilia, is diagnosed when vascular thrombosis or pregnancy morbidity occurs with persistently positive antiphospholipid antibodies (aPL). APS is a risk factor for unprovoked recurrence of pulmonary embolism (PE). Performing laboratory testing for aPL after a first unprovoked acute PE is controversial. We investigated if a specific phenotype existed in patients with unprovoked with acute PE, suggesting the need to evaluate them for APS...
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30574688/factors-associated-with-indacaterol-response-in-tuberculosis-destroyed-lung-with-airflow-limitation
#5
Tae Hoon Kim, Chin Kook Rhee, Yeon Mok Oh
BACKGROUND: Pulmonary tuberculosis can result in anatomical sequelae, and cause airflow limitation. However, there are no treatment guidelines for patients with a tuberculosis-destroyed lung. Recently, indacaterol effectiveness in chronic obstructive pulmonary disease (COPD) patients with Tuberculosis history (INFINITY) study revealed indacaterol provided bronchodilation and symptom improvement in COPD patients with a tuberculosis-destroyed lung. METHODS: We conducted a post-hoc subgroup analysis of the randomized controlled trial, the INFINITY study, to determine factors associated with indacaterol response in a tuberculosis-destroyed lung with airflow limitation...
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30574687/treatment-of-mycobacterium-avium-complex-pulmonary-disease
#6
REVIEW
Yong Soo Kwon, Won Jung Koh, Charles L Daley
The pathogen Mycobacterium avium complex (MAC) is the most common cause of nontuberculous mycobacterial pulmonary disease worldwide. The decision to initiate long-term antibiotic treatment is difficult for the physician due to inconsistent disease progression and adverse effects associated with the antibiotic treatment. The prognostic factors for the progression of MAC pulmonary disease are low body mass index, poor nutritional status, presence of cavitary lesion(s), extensive disease, and a positive acid-fast bacilli smear...
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30302954/sepsis-early-recognition-and-optimized-treatment
#7
REVIEW
Hwan Il Kim, Sunghoon Park
Sepsis is a life-threatening condition caused by infection and represents a substantial global health burden. Recent epidemiological studies showed that sepsis mortality rates have decreased, but that the incidence has continued to increase. Although a mortality benefit from early-goal directed therapy (EGDT) in patients with severe sepsis or septic shock was reported in 2001, three subsequent multicenter randomized studies showed no benefits of EGDT versus usual care. Nonetheless, the early administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis...
January 2019: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30238719/corrigendum-an-increased-proportion-of-apoptosis-in-cd4-t-lymphocytes-isolated-from-the-peripheral-blood-in-patients-with-stable-chronic-obstructive-pulmonary-disease
#8
Jinyung Ju
This corrects the article on p. 132 in vol. 81, PMID: 29372631.
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30238718/corrigendum-effects-of-macrolide-and-corticosteroid-in-neutrophilic-asthma-mouse-model
#9
Tai Joon An, Chin Kook Rhee, Ji Hye Kim, Young Rong Lee, Jin Young Chon, Chan Kwon Park, Hyoung Kyu Yoon
This corrects the article on p. 80 in vol. 81, PMID: 29332324.
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30238717/corrigendum-elucidation-of-bacterial-pneumonia-causing-pathogens-in-patients-with-respiratory-viral-infection
#10
Hwa Sik Jung, Byung Ju Kang, Seung Won Ra, Kwang Won Seo, Yangjin Jegal, Jae Bum Jun, Jiwon Jung, Joseph Jeong, Hee Jeong Jeon, Jae Sung Ahn, Taehoon Lee, Jong Joon Ahn
This corrects the article on p. 358 in vol. 80, PMID: 28905531.
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30238716/old-friends-old-wine-and-old-copd-classification-are-best
#11
EDITORIAL
Chin Kook Rhee
No abstract text is available yet for this article.
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/30238715/the-prevalence-and-risk-factors-of-latent-tuberculosis-infection-among-health-care-workers-working-in-a-tertiary-hospital-in-south-korea
#12
Jae Seuk Park
BACKGROUND: The risk of tuberculosis (TB) infection among health care workers (HCWs) is higher than as noted among workers in the general population. The prevalence and risk factors of TB infection among HCWs were assessed in a tertiary hospital in South Korea, resulting in a conclusion of an intermediate TB burden within the country. METHODS: This cross-sectional study enrolled HCWs who underwent a QuantiFERON-TB Gold In-Tube (QFT-GIT) test to detect the presence of a latent TB infection (LTBI), in patients admitted to a tertiary hospital in South Korea in 2017...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29926557/clinical-characteristics-of-false-positive-lymph-node-on-chest-ct-or-pet-ct-confirmed-by-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-lung-cancer
#13
Jongmin Lee, Young Kyoon Kim, Ye Young Seo, Eun Kyoung Choi, Dong Soo Lee, Yeon Sil Kim, Sook Hee Hong, Jin Hyoung Kang, Kyo Young Lee, Jae Kil Park, Sook Whan Sung, Hyun Bin Kim, Mi Sun Park, Hyeon Woo Yim, Seung Joon Kim
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a standard procedure to evaluate suspicious lymph node involvement of lung cancer because computed tomography (CT) and 18F-fluorodeoxyglucose positron emission tomography-CT (PET-CT) have limitations in their sensitivity and specificity. There are a number of benign causes of false positive lymph node such as anthracosis or anthracofibrosis, pneumoconiosis, old or active tuberculosis, interstitial lung disease, and other infectious conditions including pneumonia...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29926554/revised-2018-copd-clinical-practice-guideline-of-the-korean-academy-of-tuberculosis-and-respiratory-disease-a-summary
#14
REVIEW
Yong Bum Park, Chin Kook Rhee, Hyoung Kyu Yoon, Yeon Mok Oh, Seong Yong Lim, Jin Hwa Lee, Kwang Ha Yoo, Joong Hyun Ahn
Chronic obstructive pulmonary disease (COPD) results in high morbidity and mortality among patients nationally and globally. The Korean clinical practice guideline for COPD was revised in 2018. The guideline was drafted by the members of the Korean Academy of Tuberculosis and Respiratory Diseases as well as the participating members of the Health Insurance Review and Assessment Service, Korean Physicians' Association, and Korea Respiration Trouble Association. The revised guideline encompasses a wide range of topics, including the epidemiology, diagnosis, assessment, monitoring, management, exacerbation, and comorbidities of COPD in Korea...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29926552/incidence-of-adverse-effects-and-discontinuation-rate-between-patients-receiving-250-micrograms-and-500-micrograms-of-roflumilast-a-comparative-study
#15
Hyonsoo Joo, Deokjae Han, Jae Ha Lee, Chin Kook Rhee
BACKGROUND: Roflumilast is the only approved oral phosphodiesterase-4 inhibitor for the treatment of severe chronic obstructive pulmonary disease (COPD) in patients with chronic bronchitis and a history of frequent exacerbations. The purpose of this study was to examine the incidence of adverse effects associated with roflumilast treatment in a real-world setting. Further, we compared the incidence of adverse effects and the discontinuation rate among patients receiving different doses...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29926547/ct-guided-percutaneous-transthoracic-needle-biopsy-using-the-additional-laser-guidance-system-by-a-pulmonologist-with-2-years-of-experience-in-ct-guided-percutaneous-transthoracic-needle-biopsy
#16
Min Cheol Jeon, Ju Ock Kim, Sung Soo Jung, Hee Sun Park, Jeong Eun Lee, Jae Young Moon, Chae Uk Chung, Da Hyun Kang, Dong Il Park
BACKGROUND: We developed an additional laser guidance system to improve the efficacy and safety of conventional computed tomography (CT)-guided percutaneous transthoracic needle biopsy (PTNB), and we conducted this study to evaluate the efficacy and safety of our system. METHODS: We retrospectively analyzed the medical records of 244 patients who underwent CT-guided PTNB using our additional laser guidance system from July 1, 2015, to January 20, 2016. RESULTS: There were nine false-negative results among the 238 total cases...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29926546/effectiveness-and-safety-of-high-flow-nasal-cannula-oxygen-delivery-during-bronchoalveolar-lavage-in-acute-respiratory-failure-patients
#17
Eun Jin Kim, Chi Young Jung, Kyung Chan Kim
BACKGROUND: Bronchoalveolar lavage (BAL) is a necessary procedure for diagnosis of various lung diseases. High-flow nasal cannula (HFNC) oxygen delivery was recently introduced. This study aimed to investigate the safety and effectiveness of HFNC oxygen supply during BAL procedure in patients with acute respiratory failure (ARF). METHODS: Patients who underwent BAL while using HFNC at a partial pressure of oxygen in arterial blood/fraction of inspired oxygen (PaO₂/FiO₂; PF) ratio of 300 or below among patients who had been admitted from March 2013 to May 2017 were retrospectively investigated...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29926539/body-mass-index-as-a-predictor-of-acute-kidney-injury-in-critically-ill-patients-a-retrospective-single-center-study
#18
Sunmi Ju, Tae Won Lee, Jung Wan Yoo, Seung Jun Lee, Yu Ji Cho, Yi Yeong Jeong, Jong Deog Lee, Ju Young Kim, Gi Dong Lee, Ho Cheol Kim
BACKGROUND: The aim of this study was to examine the influence of body mass index (BMI) on the development of acute kidney injury (AKI) in critically ill patients in intensive care unit (ICU). METHODS: Data of patients admitted to medical ICU from December 2011 to May 2014 were retrospectively analyzed. Patients were classified into three groups according to their BMI: underweight (<18.5 kg/m²), normal (18.5-24.9 kg/m²), and overweight (≥25 kg/m²). The incidence of AKI was compared among these groups and factors associated with the development of AKI were analyzed...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29527845/the-comparison-of-clinical-variables-in-two-classifications-gold-2017-combined-assessment-and-spirometric-stage-of-chronic-obstructive-pulmonary-disease
#19
Ipek Candemir, Pinar Ergun, Dicle Kaymaz, Filiz Tasdemir, Nurcan Egesel
BACKGROUND: There are limited number of studies that investigate clinical variables instead of chronic obstructive lung disease (COPD) management according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 classification. The aim of the study was to investigate whether there was a difference between GOLD 2017 classification and spirometric stage in clinical variables in patients with COPD. The data of 427 male patients with stable COPD were investigated retrospectively...
October 2018: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/29527840/increased-risk-of-exacerbation-in-asthma-predominant-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome
#20
Jisoo Park, Eun Kyung Kim, Mi Ae Kim, Tae Hyung Kim, Jung Hyun Chang, Yon Ju Ryu, Sei Won Lee, Yeon Mok Oh, Suk Joong Yong, Won Il Choi, Kwang Ha Yoo, Ji Hyun Lee
BACKGROUND: Obstructive airway disease patients with increased variability of airflow and incompletely reversible airflow obstruction are often categorized as having asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS). ACOS is heterogeneous with two sub-phenotypes: asthma-ACOS and COPD-ACOS. The objective of this study was to determine the difference in risk of exacerbation between the two sub-phenotypes of ACOS. METHODS: A total of 223 patients exhibiting incompletely reversible airflow obstruction with increased variability (spirometrically defined ACOS) were enrolled...
October 2018: Tuberculosis and Respiratory Diseases
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