Zhongmian Zhang, Weitian Yan, Xiyan Zhang, Jiaqi Wang, Zhonghan Zhang, Zili Lin, Lan Wang, Jiaqin Chen, Daming Liu, Wen Zhang, Zhihong Li
BACKGROUND: Peptic ulcer disease has been a major threat to the world's population, which remains a significant cause of hospitalization worldwide and healthcare resource utilization. OBJECTIVES: We aimed to describe the global burden, trends, and inequalities of peptic ulcer disease. DESIGN: An observational study was conducted. METHODS: In this secondary analysis of the Global Burden of Disease, Injuries, and Risk Factors Study 2019, we extracted data for age-standardized incidence rates (ASIRs), disability-adjusted life year rates (ASDRs), and mortality rates (ASMRs); then, we stratified by age, level of regionals, and country; subsequently, we calculated estimated annual percentage changes (EAPC) of ASIR, ASDR, ASMR, and quantified cross-country inequalities in peptic ulcer disease mortality...
2023: Therapeutic Advances in Gastroenterology