journal
https://read.qxmd.com/read/38859924/enhancing-visual-communication-through-representation-learning
#1
JOURNAL ARTICLE
YuHan Wei, ChangWook Lee, SeokWon Han, Anna Kim
INTRODUCTION: This research aims to address the challenges in model construction for the Extended Mind for the Design of the Human Environment. Specifically, we employ the ResNet-50, LSTM, and Object Tracking Algorithms approaches to achieve collaborative construction of high-quality virtual assets, image optimization, and intelligent agents, providing users with a virtual universe experience in the context of visual communication. METHODS: Firstly, we utilize ResNet-50 as a convolutional neural network model for generating virtual assets, including objects, characters, and environments...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38859923/case-report-primary-familial-brain-calcification-associated-with-a-rare-pdgfrb-variant-coexisting-with-nontraumatic-osteonecrosis-of-the-femoral-head
#2
JOURNAL ARTICLE
Conghui Cao, Jing Luo, Xiaoli Wang
Primary familial brain calcification (PFBC) is a rare genetic neurodegenerative disorder characterized by bilateral calcifications in the brain. PFBC may manifest with a broad spectrum of motor, cognitive, and neuropsychiatric symptoms. Several causal genes have been identified in PFBC, which are inherited as both autosomal dominant and autosomal recessive traits. Herein, we present the case of a Chinese family diagnosed with PFBC. The family members carry a rare heterozygous variant (p. R334Q) in exon 7 of platelet-derived growth factor receptor β ( PDGFRB ) gene...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38859922/exploring-the-role-of-underrepresented-populations-in-polygenic-risk-scores-for-neurodegenerative-disease-risk-prediction
#3
JOURNAL ARTICLE
Kathryn Step, Carene Anne Alene Ndong Sima, Ignacio Mata, Soraya Bardien
No abstract text is available yet for this article.
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38855443/editorial-human-in-the-loop-system-design-and-control-adaptation-for-behavior-assistant-robots
#4
EDITORIAL
Bi Zhang, Yuquan Leng, Benyan Huo, Ningbo Yu, Xu Jin
No abstract text is available yet for this article.
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38855442/causal-links-between-gut-microbiomes-cytokines-and-risk-of-different-subtypes-of-epilepsy-a-mendelian-randomization-study
#5
JOURNAL ARTICLE
Youjia Qiu, Bingyi Song, Minjia Xie, Yuchen Tao, Ziqian Yin, Menghan Wang, Chao Ma, Zhouqing Chen, Zhong Wang
OBJECTIVE: Recent research suggests a potential link between the gut microbiome (GM) and epilepsy. We undertook a Mendelian randomization (MR) study to determine the possible causal influence of GM on epilepsy and its various subtypes, and explore whether cytokines act as mediators. METHODS: We utilized Genome-Wide Association Study (GWAS) summary statistics to examine the causal relationships between GM, cytokines, and four epilepsy subtypes. Furthermore, we assessed whether cytokines mediate the relationship between GM and epilepsy...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38855441/binocularly-suppressed-stimuli-induce-brain-activities-related-to-aesthetic-emotions
#6
JOURNAL ARTICLE
Hideyuki Hoshi, Akira Ishii, Yoshihito Shigihara, Takahiro Yoshikawa
INTRODUCTION: Aesthetic emotions are a class of emotions aroused by evaluating aesthetically appealing objects or events. While evolutionary aesthetics suggests the adaptive roles of these emotions, empirical assessments are lacking. Previous neuroscientific studies have demonstrated that visual stimuli carrying evolutionarily important information induce neural responses even when presented non-consciously. To examine the evolutionary importance of aesthetic emotions, we conducted a neuroscientific study using magnetoencephalography (MEG) to measure induced neural responses to non-consciously presented portrait paintings categorised as biological and non-biological and examined associations between the induced responses and aesthetic ratings...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38855440/rich-club-organization-of-whole-brain-spatio-temporal-multilayer-functional-connectivity-networks
#7
JOURNAL ARTICLE
Jianhui Zheng, Yuhao Cheng, Xi Wu, Xiaojie Li, Ying Fu, Zhipeng Yang
OBJECTIVE: In this work, we propose a novel method for constructing whole-brain spatio-temporal multilayer functional connectivity networks (FCNs) and four innovative rich-club metrics. METHODS: Spatio-temporal multilayer FCNs achieve a high-order representation of the spatio-temporal dynamic characteristics of brain networks by combining the sliding time window method with graph theory and hypergraph theory. The four proposed rich-club scales are based on the dynamic changes in rich-club node identity, providing a parameterized description of the topological dynamic characteristics of brain networks from both temporal and spatial perspectives...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38846718/sparse-blind-spherical-deconvolution-of-diffusion-weighted-mri
#8
JOURNAL ARTICLE
Clément Fuchs, Quentin Dessain, Nicolas Delinte, Manon Dausort, Benoît Macq
Diffusion-weighted magnetic resonance imaging provides invaluable insights into in-vivo neurological pathways. However, accurate and robust characterization of white matter fibers microstructure remains challenging. Widely used spherical deconvolution algorithms retrieve the fiber Orientation Distribution Function (ODF) by using an estimation of a response function, i.e., the signal arising from individual fascicles within a voxel. In this paper, an algorithm of blind spherical deconvolution is proposed, which only assumes the axial symmetry of the response function instead of its exact knowledge...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38846717/research-application-of-session-rpe-in-monitoring-the-training-load-of-elite-endurance-athletes
#9
JOURNAL ARTICLE
Shengjie Yang, Yiquan Yin, Zhaoyi Qiu, Qingjun Meng
PURPOSE: TRIMP and sRPE are both representative indicators of training load(TL), and the correlation between two has been widely demonstrated across various sports. The aim of this study was to investigate the reliability of sRPE-TRIMP correlation across different intensities/duration of training in cross-country skiing, and whether sRPE can serve as an validity supplement to TRIMP data in cases of lost heart rate data. METHOD: 10 athletes were used as the experimental objects...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38846716/advancements-and-challenges-in-amyotrophic-lateral-sclerosis
#10
REVIEW
David Bradford, Kathleen E Rodgers
Amyotrophic lateral sclerosis (ALS) continues to pose a significant challenge due to the disease complexity and heterogeneous manifestations. Despite recent drug approvals, there remains a critical need for the development of more effective therapies. This review explores the underlying mechanisms involved; including neuroinflammation, glutamate mediated excitotoxicity, mitochondrial dysfunction, and hypermetabolism, and how researchers are trying to develop novel drugs to target these pathways. While progress has been made, the unmet need of ALS patients highlights the urgency for continued research and resource allocation in the pursuit of effective treatments...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38846715/atrophy-patterns-in-hippocampal-subregions-and-their-relationship-with-cognitive-function-in-fibromyalgia-patients-with-mild-cognitive-impairment
#11
JOURNAL ARTICLE
Yingming Long, Xinyan Xie, Yingwei Wang, Jinping Xu, Ziyi Gao, Xiaokun Fang, Tong Xu, Nan Zhang, Dongling Lv, Ting Wu
OBJECTIVES: Fibromyalgia (FM) has been associated with decreased hippocampal volume; however, the atrophy patterns of hippocampal subregions have not yet been identified. We therefore aimed to evaluate the volumes of hippocampal subregions in FM patients with mild cognitive impairment (MCI), and to explore the relationship between different subregional alterations and cognitive function. METHODS: The study included 35 FM patients (21 with MCI and 14 without MCI) and 35 healthy subjects...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38846714/state-and-frequency-dependence-in-autonomic-rebalance-mediated-by-intradermal-auricular-electroacupuncture-stimulation
#12
JOURNAL ARTICLE
Sen Yang, Yu-Rui Wu, Zheng Zhan, Yan-Hong Pan, Jin-Feng Jiang
BACKGROUND: Vagus nerve stimulation (VNS) improves diseases such as refractory epilepsy and treatment-resistant depression, likely by rebalancing the autonomic nervous system (ANS). Intradermal auricular electro-acupuncture stimulation (iaES) produces similar effects. The aim of this study was to determine the effects of different iaES frequencies on the parasympathetic and sympathetic divisions in different states of ANS imbalance. METHODS: We measured heart rate variability (HRV) and heart rate (HR) of non-modeled (normal) rats with the treatment of various frequencies to determine the optimal iaES frequency...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38846713/the-role-of-cortical-structural-variance-in-deep-learning-based-prediction-of-fetal-brain-age
#13
JOURNAL ARTICLE
Hyeokjin Kwon, Sungmin You, Hyuk Jin Yun, Seungyoon Jeong, Anette Paulina De León Barba, Marisol Elizabeth Lemus Aguilar, Pablo Jaquez Vergara, Sofia Urosa Davila, P Ellen Grant, Jong-Min Lee, Kiho Im
BACKGROUND: Deep-learning-based brain age estimation using magnetic resonance imaging data has been proposed to identify abnormalities in brain development and the risk of adverse developmental outcomes in the fetal brain. Although saliency and attention activation maps have been used to understand the contribution of different brain regions in determining brain age, there has been no attempt to explain the influence of shape-related cortical structural features on the variance of predicted fetal brain age...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38841098/hidden-regulators-the-emerging-roles-of-lncrnas-in-brain-development-and-disease
#14
REVIEW
Farah Alammari, Ensaf M Al-Hujaily, Alaa Alshareeda, Nada Albarakati, Batla S Al-Sowayan
Long non-coding RNAs (lncRNAs) have emerged as critical players in brain development and disease. These non-coding transcripts, which once considered as "transcriptional junk," are now known for their regulatory roles in gene expression. In brain development, lncRNAs participate in many processes, including neurogenesis, neuronal differentiation, and synaptogenesis. They employ their effect through a wide variety of transcriptional and post-transcriptional regulatory mechanisms through interactions with chromatin modifiers, transcription factors, and other regulatory molecules...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38841097/dti-alps-index-decreased-in-patients-with-type-2-diabetes-mellitus
#15
JOURNAL ARTICLE
Shuncheng Yu, Hongjun Jiang, Langxuan Yu, Tieli Liu, Chun Yang, Jiajun Cao, Qingwei Song, Yanwei Miao, Weiwei Wang
BACKGROUNDS: Type 2 Diabetes Mellitus (T2DM) has become a significant global public health issue, characterized by a rising prevalence and associated deficits across multiple organ systems. Our study aims to utilize the DTI-ALPS technique to assess the change of ALPS index in T2DM patients, and to explore whether such changes are correlated with cognition level and diffusion parameters. METHODS: The study involved 41 patients with T2DM (mean age, 60.49 ± 8...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38841096/deciphering-the-brain-gut-axis-elucidating-the-link-between-cerebral-cortex-structures-and-functional-gastrointestinal-disorders-via-integrated-mendelian-randomization
#16
JOURNAL ARTICLE
Zhiwei Xu, Fenglan Ning, Xuecheng Zhang, Qi Wang, Yimei Zhang, Yiting Guo, Hongling Jia
BACKGROUND: Observational studies have suggested associations between functional gastrointestinal disorders (FGIDs) and variations in the cerebral cortex. However, the causality of these relationships remains unclear, confounded by anxiety and depression. To clarify these causal relationships and explore the mediating roles of anxiety and depression, we applied univariate, multivariable, and mediation Mendelian randomization (MR) analyses. METHOD: We utilized genome-wide association study (GWAS) summary data from the FinnGen database and the ENIGMA consortium, identifying genetic variants associated with irritable bowel syndrome (IBS), functional dyspepsia (FD), and cerebral cortex structures...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38841095/effect-of-surface-electrode-recording-area-on-compound-muscle-action-potential-scan-processing-for-motor-unit-number-estimation
#17
JOURNAL ARTICLE
Dan Zhang, Zhiyuan Lu, Weijun Gong, Ping Zhou
INTRODUCTION: MScanFit is a model-based algorithm for motor unit number estimation (MUNE) from compound muscle action potential (CMAP) scan data. It is a clinically applicable tool because of its quick and automatic implementation. Electrodes with different recording areas were employed to record CMAP scan data in existing studies. However, the effect of electrode recording area on MScanFit MUNE and other CMAP scan parameters has not been studied. METHODS: CMAP scan was performed on the abductor pollicis brevis muscle of both hands on 14 healthy subjects using three different electrodes with recording areas of 10 mm × 10 mm, 11 mm × 14 mm, and 22 mm × 26 mm, respectively...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38841094/spatiotemporal-consistency-analysis-of-cerebral-small-vessel-disease-an-rs-fmri-study
#18
JOURNAL ARTICLE
Jie Yang, Rui Xiao, Yujian Liu, Chaoliang He, Limei Han, Xiaoya Xu, Meining Chen, Jianquan Zhong
INTRODUCTION: Cerebral small vessel disease (SVD) affects older adults, but traditional approaches have limited the understanding of the neural mechanisms of SVD. This study aimed to explore the effects of SVD on brain regions and its association with cognitive decline using the four-dimensional (spatiotemporal) consistency of local neural activity (FOCA) method. METHODS: Magnetic resonance imaging data from 42 patients with SVD and 38 healthy controls (HCs) were analyzed using the FOCA values...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38841093/short-latency-prepulse-inhibition-of-the-trigeminal-blink-reflex
#19
JOURNAL ARTICLE
Megumi Shingaki, Yasushi Itoh, Bayasgalan Borgil, Tetsuo Kida, Koji Inui
Prepulse inhibition (PPI) is a well-established phenomenon wherein a weak sensory stimulus attenuates the startle reflex triggered by a subsequent strong stimulus. Within the circuit, variations in target responses observed for PPI paradigms represent prepulse-induced excitability changes. However, little is known about the mechanism of PPI. Here, we focused on short-latency PPI of the trigeminal blink reflex R1 signal with an oligosynaptic reflex arc through the principal sensory trigeminal nucleus and the facial nucleus...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38835837/low-t3-syndrome-is-associated-with-the-severity-of-myelin-oligodendrocyte-glycoprotein-antibody-associated-disease-exacerbation
#20
JOURNAL ARTICLE
Yuqing Wu, Hao Zhou, Xiaojiao Ci, Jie Lu
BACKGROUND: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare autoimmune inflammatory disease of the central nervous system, (CNS) different from multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD). While numerous studies have delved into the involvement of thyroid antibodies (ATAbs) and thyroid function in NMOSD and MS. The objective of this study is to explore the clinical significance of thyroid dysfunction and ATAbs abnormalities in adult patients with MOGAD...
2024: Frontiers in Neuroscience
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