Geoffrey Chern-Yee Tan, Ziying Wang, Ethel Siew Ee Tan, Rachel Jing Min Ong, Pei En Ooi, Danan Lee, Nikita Rane, Sheryl Yu Xuan Tey, Si Ying Chua, Nicole Goh, Glynis Weibin Lam, Atlanta Chakraborty, Anthony Khye Loong Yew, Sin Kee Ong, Jin Lin Kee, Xin Ying Lim, Nawal Hashim, Sharon Huixian Lu, Michael Meany, Serenella Tolomeo, Christopher Asplund Lee, Hong Ming Tan, Jussi Keppo
INTRODUCTION: The heterogeneity of depressive and anxiety disorders complicates clinical management as it may account for differences in trajectory and treatment response. Self-schemas, which can be determined by Self-Referential Judgements (SRJs), are heterogeneous yet stable. SRJs have been used to characterize personality in the general population and shown to be prognostic in depressive and anxiety disorders. METHODS: In this study, we used SRJs from a Self-Referential Encoding Task (SRET) to identify clusters from a clinical sample of 119 patients recruited from the Institute of Mental Health presenting with depressive or anxiety symptoms and a non-clinical sample of 115 healthy adults...
2023: Frontiers in Neuroinformatics