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Deutsches Ärzteblatt International

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https://read.qxmd.com/read/30722840/hematological-malignancies-in-adults-with-a-family-predisposition
#1
Tilmann Bochtler, Georg-Martin Haag, Sarah Schott, Matthias Kloor, Alwin Krämer, Carsten Müller-Tidow
BACKGROUND: Some hematological malignancies arise in persons with a hereditary predisposition. The hereditary nature of these diseases often goes unrecognized, particularly when symptoms begin in adulthood. METHODS: This review is based on pertinent publications retrieved by a selective search in PubMed. RESULTS: Many rare germline mutations have been identified that lead to acute leukemia and myelodysplastic syndromes. They differ from one another with respect to their penetrance, the age of onset of disease, and the clinical manifestations...
December 14, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30722839/mechanical-ventilation-and-extracorporeal-membrane-oxygena-tion-in-acute-respiratory-insufficiency
#2
Falk Fichtner, Onnen Moerer, Sven Laudi, Steffen Weber-Carstens, Monika Nothacker, Udo Kaisers
BACKGROUND: Mechanical ventilation is life-saving for patients with acute respiratory insufficiency. In a German prevalence study, 13.6% of patients in intensive care units received mechanical ventilation for more than 12 hours; 20% of these patients received mechanical ventilation as treatment for acute respiratory distress syndrome (ARDS). The new S3 guideline is the first to contain recommendations for the entire process of treatment in these groups of patients (indications, ventilation modes/parameters, ac- companying measures, treatments for refractory impairment of gas exchange, weaning, and follow-up care)...
December 14, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30722838/tuberculous-pleural-effusion
#3
Hilte Friederike Geerdes-Fenge, Emil Christian Reisinger, Juliane Becker
No abstract text is available yet for this article.
December 14, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30722837/yoga-in-arterial-hypertension
#4
Holger Cramer, Charlotte Sellin, Dania Schumann, Gustav Dobos
BACKGROUND: Yoga seems to exert its effect against arterial hypertension mainly through the associated breathing and meditation techniques, and less so through yoga postures. The goal of this trial was to compare the blood pressure-lowering effect of yoga interventions with and without yoga postures in patients with arterial hypertension. METHODS: 75 patients taking medications for arterial hypertension (72% women, mean age 58.7 ± 9.5 years) were randomized into three groups: a yoga intervention group with yoga postures (25 patients, of whom 5 dropped out of the trial before its end), a yoga intervention group without yoga postures (25 patients, 3 dropouts), and a wait list control group (25 patients, one dropout)...
December 14, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30678752/new-microbiological-techniques-in-the-diagnosis-of-bloodstream-infections
#5
Evgeny A Idelevich, Udo Reischl, Karsten Becker
BACKGROUND: When a bloodstream infection is suspected, the preliminary and definitive results of culture-based microbiological testing arrive too late to have any influence on the initial choice of empirical antibiotic treatment. METHODS: This review is based on pertinent publications retrieved by a selective search of the literature and on the authors' clinical and scientific experience. RESULTS: A number of technical advances now enable more rapid microbiological diagnosis of bloodstream infections...
December 7, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30678751/naturopathic-treatment-and-complementary-medicine-in-surgical-practice
#6
Ann-Kathrin Lederer, Christine Schmucker, Lampros Kousoulas, Stefan Fichtner-Feigl, Roman Huber
BACKGROUND: Many patients in Germany use naturopathic treatments and complementary medicine. Surveys have shown that many also use them as a concomitant treatment to surgery. METHODS: Multiple databases were systematically searched for systematic reviews, controlled trials, and experimental studies concerning the use of naturopathic treatments and complementary medicine in the management of typical post-operative problems (PROSPERO CRD42018095330). RESULTS: Of the 387 publications identified by the search, 76 fulfilled the inclusion criteria...
December 7, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30642429/medicine-in-the-penal-system
#7
Annette Opitz-Welke, Marc Lehmann, Peter Seidel, Norbert Konrad
BACKGROUND: Infectious diseases, substance dependencies, and dental diseases are the most important health problems affecting incarcerated persons. In Germany, for example, prisoners are 48 to 69 times more likely to be infected with the hepatitis C virus (HCV) than the general population, and 7 to 12 times more likely to be infected with the human immunodeficiency virus (HIV). The prevalence of mental illnesses is also markedly higher in the incarcerated than in the general population...
November 30, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30642428/the-investigation-of-hematuria
#8
Christian Bolenz, Bernd Schröppel, Andreas Eisenhardt, Bernd J Schmitz-Dräger, Marc-Oliver Grimm
BACKGROUND: Hematuria can be either grossly visible (macrohematuria) or only detectable under a microscope (microhematuria). Microhematuria is often asymptomatic and has a prevalence of 4-5% in routine clinical practice. It may be due to an underlying disease of the kidneys or the urogenital tract. In this article, we provide an overview of the causes of hematuria and of the recommendations of current guidelines for its diagnostic evaluation. A risk-adapted diagnostic strategy for the evaluation of asymptomatic microhematuria (aMH) is presented...
November 30, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30636674/hospital-volume-in-hospital-mortality-and-failure-to-rescue-in-esophageal-surgery
#9
Ulrike Nimptsch, Thomas Haist, Christian Krautz, Robert Grützmann, Thomas Mansky, Dietmar Lorenz
BACKGROUND: In Germany, complex esophageal surgery is often performed in hospitals with low case numbers. For these procedures, an association exists between hospital case numbers and treatment outcomes, possibly because of differences in complication management. This aspect of the association between volume and outcome in esophageal surgery has not yet been studied in Germany. METHODS: On the basis of nationwide hospital discharge data (DRG statistics) from the years 2010 to 2015, the association between volume and outcome was analyzed in relation to in-hospital mortality, the frequency of complications, and the mortality of patients who had complications...
November 23, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30636673/diagnosis-splenosis
#10
Christoph Erxleben, Roland Scherer, Thomas Elgeti
No abstract text is available yet for this article.
November 23, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30636672/the-effectiveness-of-leech-therapy-in-chronic-low-back-pain
#11
Christoph-Daniel Hohmann, Rainer Stange, Nico Steckhan, Sibylle Robens, Thomas Ostermann, Arion Paetow, Andreas Michalsen
BACKGROUND: Leech therapy has been found to be effective in the treatment of a number of chronic musculoskeletal pain syndromes. Leeches are also often used empirically to treat chronic low back pain, but data from clinical trials have been lacking to date. We therefore conducted the first randomized trial of leech therapy for chronic low back pain. METHODS: Patients with chronic low back pain were randomized to receive either a single session of local treatment with 4-7 leeches or four weekly sessions of exercise therapy (1 hour each) led by a physical therapist...
November 23, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30602412/drop-metastasis-of-type-b-thymoma-5-years-after-resection
#12
Matthias B Heldwein, Fabian Doerr, Khosro Hekmat
No abstract text is available yet for this article.
November 16, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30602411/sepsis-associated-purpura-fulminans-due-to-klebsiella-oxytoca
#13
Sigrid C Disse, Sascha Meyer, Ali Baghai-Arassi
No abstract text is available yet for this article.
November 16, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30602410/oral-anticoagulation
#14
Ertunc Altiok, Nikolaus Marx
BACKGROUND: Much new evidence on oral anticoagulation has come to light in recent years. Non-vitamin-K-dependent oral anti- coagulants (NOAC) have been developed and have been introduced into clinical practice. In this review, we present the current state of the evidence on anticoagulation for various indications with vitamin K antagonists (VKA) and with NOAC. METHODS: This review is based on pertinent articles retrieved by a selective search in PubMed (search terms: anticoagulation, atrial fibrillation, prosthetic valve, thrombosis, pulmonary embolism) and on specialty society recommendations and relevant guidelines from the years 2000-2018...
November 16, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30602409/abuse-as-a-cause-of-childhood-fractures
#15
Oliver Berthold, Bernd Frericks, Thilo John, Vera Clemens, Jörg M Fegert, Arpad von Moers
BACKGROUND: It is well known that physical abuse of children all too often escapes detection. Fractures are among the potential consequences of physical abuse but are also com- mon in childhood because of accidents. A question frequently addressed to the Medical Child Protection Hotline (Medizini- sche Kinderschutzhotline) is how fractures due to abuse can be distinguished from accidental fractures. METHODS: This review is based on pertinent publications retrieved by a search in PubMed and in the Cochrane Data- base, as well as on the authors' experience in a pediatric emergency department with ca...
November 16, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30573009/the-nomenclature-definition-and-distinction-of-types-of-shock
#16
Thomas Standl, Thorsten Annecke, Ingolf Cascorbi, Axel R Heller, Anton Sabashnikov, Wolfram Teske
BACKGROUND: A severe mismatch between the supply and demand of oxygen is the common feature of all types of shock. We present a newly developed, clinically oriented classification of the various types of shock and their therapeutic implications. METHODS: This review is based on pertinent publications (1990-2018) retrieved by a selective search in PubMed, and on the relevant guidelines and meta-analyses. RESULTS: There are only four major categories of shock, each of which is mainly related to one of four organ systems...
November 9, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30573008/lyme-neuroborreliosis
#17
Sebastian Rauer, Stefan Kastenbauer, Volker Fingerle, Klaus-Peter Hunfeld, Hans-Iko Huppertz, Rick Dersch
BACKGROUND: The new German S3 guideline on Lyme neuroborreliosis is intended to provide physicians with scientifically based information and recommendations on the diagnosis and treatment of this disease. METHODS: The scientific literature was systematically searched and the retrieved publications were assessed at the German Cochrane Center (Deutsches Cochrane Zentrum) in Freiburg in the 12 months beginning in March 2014. In addition to the main search terms "Lyme disease," "neuroborreliosis," "Borrelia," and "Bannwarth," 28 further terms relating to neurological manifestations of the disease were used for the search in the Medline and Embase databases and in the Cochrane Central Register of Controlled Trials...
November 9, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30381135/in-reply
#18
Roland Goldbrunner
No abstract text is available yet for this article.
November 5, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30381134/the-study-was-subject-to-considerable-bias
#19
Malte Haupt
No abstract text is available yet for this article.
November 5, 2018: Deutsches Ärzteblatt International
https://read.qxmd.com/read/30381133/a-slowly-receding-hairline
#20
Bijan Koushk Jalali, Christian Tigges, Alexander Kreuter
No abstract text is available yet for this article.
November 5, 2018: Deutsches Ärzteblatt International
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