journal
Journals Gastroenterology Research and ...

Gastroenterology Research and Practice

https://read.qxmd.com/read/36644482/risk-factors-associated-with-acute-pancreatitis-after-percutaneous-biliary-intervention-we-do-not-know-nearly-enough
#41
REVIEW
Jing Song, Jun Deng, Feng Wen
Percutaneous transhepatic cholangiodrainage (PTCD) and percutaneous transhepatic biliary stenting (PTBS) may be used as a palliative treatment for inoperable patients with malignant biliary obstruction (MBO) to improve the prognosis and their quality of life. However, acute pancreatitis is a common and severe complication that cannot be ignored after PTCD and PTBS in patients with MBO. A few cases may develop severe pancreatitis with a higher mortality rate. In this study, we summarize the known risk factors for acute pancreatitis after percutaneous biliary interventional procedures and investigate possible risk factors to reduce its occurrence by early identifying high-risk patients and taking appropriate measures...
2023: Gastroenterology Research and Practice
https://read.qxmd.com/read/36388633/early-post-operative-endoscopy-is-associated-with-lower-surgical-recurrence-of-crohn-s-disease-a-retrospective-study-of-three-successive-cohorts
#42
JOURNAL ARTICLE
Caroline Amicone, Carla Coimbra Marques, Catherine Reenaers, Catherine Van Kemseke, Laurence Seidel, Edouard Louis
BACKGROUND: The severity of endoscopic recurrence during the first year after intestinal resection for Crohn's disease is predictive of clinical recurrence. The aim of our study was to assess the impact of the implementation of an ileocolonoscopy during the first year after surgery on surgical recurrence. METHODS: All patients who underwent a first intestinal resection for Crohn's disease between 1992 and 2018 at the University Hospital of Liège were retrospectively included...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36329782/serum-lactate-dehydrogenase-is-a-sensitive-predictor-of-systemic-complications-of-acute-pancreatitis
#43
JOURNAL ARTICLE
Dong-Ni Huang, Hao-Jie Zhong, Ying-Li Cai, Wen-Rui Xie, Xing-Xiang He
BACKGROUND: Acute pancreatitis (AP) is a common and potentially life-threatening inflammatory disease that can cause various complications, including systemic inflammatory response syndrome (SIRS), pleural effusion, ascitic fluid, myocardial infarction, and acute kidney injury (AKI). However, there is still a lack of rapid and effective indicators to assess the disease. The aim of this study was to investigate the associations of high serum lactate dehydrogenase (LDH) levels with AP severity and systemic complications...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36317106/detection-and-treatment-of-helicobacter-pylori-problems-and-advances
#44
REVIEW
Hang Yang, Liwen Guan, Bing Hu
Helicobacter pylori ( H. pylori ) infection is chronic and etiologically linked to gastric cancer (GC) derived from gastric epithelium. The potential mechanism is complex, covering chronic inflammation, epithelial senescence, NF- κ B activation, the cytotoxin-associated gene A protein translocation, and related abnormal signaling pathways. In clinical practice, the test-and-treat strategy, endoscopy-based strategy, and (family-based) screen-and-treat strategy are recommended to detect H. pylori and prevent GC...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36311294/znf521-is-correlated-with-tumor-immune-cell-infiltration-and-act-as-a-valuable-prognostic-biomarker-in-gastric-cancer
#45
JOURNAL ARTICLE
Li Li, Zheng-Hui Liu, Hui-Ju Wang, Lei Wang, Guo-Qing Ru, Yuan-Yu Wang
Aim: To explore the correlations between the expression of zinc finger protein 521 (ZNF521) with immune invasion and prognosis of gastric cancer. Methods: Expression of ZNF521 was examined by immunohistochemistry in gastric cancer cases. Kaplan-Meier plotter was used to determine the relationships between ZNF521 and prognosis. TIMER and GEPIA were used to analyze the correlation between ZNF521 expression and gene markers of immune cell infiltration. Results: The expression of ZNF521 was up-regulated in gastric cancer samples...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36304789/feasibility-of-novel-magnetically-controlled-cable-capsule-endoscopy-system-in-vitro-experiments-for-gastric-examination
#46
JOURNAL ARTICLE
Yaoping Zhang, Lina Qu, Yani Gou, Jinyong Hao, Xiaojun Huang
Background: Magnetically controlled capsule endoscopy has been shown to be feasible for the examination of gastric diseases. However, there may be problems, such as low image quality, incomplete esophageal observation, and capsule retention. We developed a novel magnetically controlled cable capsule endoscopy (MCCCE) system and evaluated its feasibility through in vitro experiments. Methods: Three experienced endoscopists performed MCCCE on the plastic stomach model and the excised porcine stomach model 5 times, respectively...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36304788/jaundice-on-presentation-is-associated-with-higher-in-patient-mortality-and-complications-in-patients-admitted-for-acute-pancreatitis-a-retrospective-study-based-on-national-inpatient-sample-database
#47
JOURNAL ARTICLE
Nishit Patel, Krishna Bodrya, Kirten Patel, Nishi Patel, Dhruvanshu Patel, Ronak Modi, Ayaz Matin
Pancreatitis usually presents with characteristic abdominal pain, radiological findings, and elevated lipase. The presence of jaundice may hint at a biliary etiology; however, it is not always present. We hypothesized that the presence of jaundice is associated with worse outcomes in patients admitted with pancreatitis. We conducted a retrospective analysis using the National Inpatient Sample, inquiring about patients admitted with pancreatitis with and without jaundice between October 2015 and December 2017...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36275426/international-normalized-ratio-to-albumin-ratio-as-a-novel-marker-of-upper-gastrointestinal-bleeding-severity
#48
JOURNAL ARTICLE
Jeongwoo Choi, Je Seop Lee, Solmoon Lee, Yong Won Kim, Yoonsuk Lee, Tae Youn Kim
INTRODUCTION: Upper gastrointestinal bleeding (UGIB) is a potentially life-threatening gastrointestinal emergency, and effective management depends on early risk stratification. The Glasgow-Blatchford and Rockall scores are commonly used prognostic measures for UGIB, although these scoring systems are relatively difficult to apply in early emergency settings. AIMS65 with five items, albumin, international normalized ratio, mental status, systolic blood pressure, and age (>65 years), showed efficacy in predicting long-term hospitalization and mortality...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36275425/the-impact-of-ascitic-paracentesis-on-symptomatic-outcomes-in-palliative-patients-3-year-experience-of-a-melbourne-inpatient-palliative-care-unit-using-palliative-care-outcomes-collaboration-assessments
#49
JOURNAL ARTICLE
Kiran Iyer, Lucy Kernick
Background: Ascites formation is a common occurrence in patients receiving palliative care. This is associated with symptoms that may respond to drainage. Aim: To review and quantify ascites-related symptoms pre- and post-paracentesis to evaluate its benefit in an inpatient palliative care setting. Methods: A retrospective audit of patients admitted to an inpatient palliative care unit who underwent paracentesis between November 2016 to June 2020 was performed...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36275424/high-serum-squamous-cell-carcinoma-antigen-level-associated-with-remission-of-mild-moderate-dysplasia-of-the-esophagus-a-nested-case-control-study
#50
JOURNAL ARTICLE
Hui Su, Kuiliang Liu, Yanjie Zhao, Feng Shi, Yuchen Li, Jiangping Wu, Qingkun Song
Background: The esophageal epithelial dysplasia is the precancerous lesion. This study aimed to investigate the association between the serum squamous cell carcinoma antigen (SCCA) and the remission of esophageal squamous mild or moderate dysplasia. Methods: We performed a nested case-control study. Patients with mild/moderate dysplasia of the esophageal squamous epithelium were enrolled in this study during the years of 2013-2015 and received a follow-up endoscopy during 2017-2018...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36275423/pre-antibiotic-treatment-followed-by-prolonged-repeated-faecal-microbiota-transplantation-improves-symptoms-and-quality-of-life-in-patients-with-irritable-bowel-syndrome-an-observational-australian-clinical-experience
#51
JOURNAL ARTICLE
Harrison Hamblin, Anoja W Gunaratne, Annabel Clancy, Denise Pilarinos, Antoinette LeBusque, Marie Vic M Dawson, Thomas J Borody
Background: The use of faecal microbiota transplantation (FMT) in irritable bowel syndrome (IBS) has frequently failed to induce long-term symptomatic improvement. The use of multiple FMT infusions is one proposed mechanism through which the efficacy of FMT can be amplified. Aims: To evaluate the safety and efficacy of a novel six-month FMT treatment protocol in IBS. Methods: Patients diagnosed with IBS confirmed by Rome IV Criteria were recruited for single-centre, single-arm, prospective clinical observational study...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36246456/safety-and-efficacy-of-the-supine-position-with-the-right-shoulder-raised-versus-the-left-lateral-position-in-peroral-endoscopic-myotomy-for-achalasia-a-large-sample-retrospective-study
#52
JOURNAL ARTICLE
Nanjun Wang, Ningli Chai, Longsong Li, Yawei Bi, Shengzhen Liu, Wengang Zhang, Shasha Wang, Enqiang Linghu
Background: The correct surgical position is very important in the treatment of peroral endoscopic myotomy (POEM) for achalasia, which can make the procedure safer and more efficient. Currently, there are two commonly used positions: the supine position with the right shoulder raised and the left lateral position. This study aims to evaluate the differences in the safety and efficacy of these two positions. Methods: We conducted a retrospective study of 702 patients with achalasia undergoing POEM from December 2010 to December 2020...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36226130/alterations-of-serum-bile-acid-profile-in-patients-with-crohn-s-disease
#53
JOURNAL ARTICLE
Rui Sun, Jingjing Jiang, Ling Yang, Lu Chen, Hong Chen
Background: Bile acid (BA) metabolism may be influenced by gut dysbiosis and alterations of intestinal epithelium in patients with Crohn's disease (CD). Here, we aimed at investigating the alterations of serum BA profile in CD patients and analyzing the correlation between BAs and CD disease activity. Methods: A total of 62 CD patients (29 active and 33 remission) and 33 healthy volunteers (HVs) were enrolled in this retrospective study. Serum BA profiles were measured by liquid chromatography-tandem mass spectrometry...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36134174/bile-reflux-gastritis-insights-into-pathogenesis-relevant-factors-carcinomatous-risk-diagnosis-and-management
#54
REVIEW
Xiaolan Shi, Zijiao Chen, Yi Yang, Su Yan
Bile reflux gastritis (BRG), a kind of gastrointestinal disorder in clinical practice, is characterized by regurgitation and inflammation. However, lack of guidelines leads to simple cognition and even ignorance of this disease for clinicians. Primarily, making the pathogenesis of BRG clear contributes to a correct and general understanding of this disease for physicians. Next, although recently there has been an increasing awareness among researchers in terms of the relevant factors for BRG, further studies involving large samples are still required to certify the relationship between them explicitly...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36089982/outcomes-of-pediatric-patients-with-crohn-s-disease-received-infliximab-or-exclusive-enteral-nutrition-during-induction-remission
#55
JOURNAL ARTICLE
Yao Lv, Yue Lou, Gan Yang, Youyou Luo, Jingan Lou, Qi Cheng, Jindan Yu, Youhong Fang, Hong Zhao, Kerong Peng, Jie Chen
Background: Both exclusive enteral nutrition (EEN) and infliximab (IFX) are recommended as induction therapy for pediatric Crohn's disease (CD). Our aim was to compare long-term disease outcomes of patients initially received with either IFX or EEN. Methods: Medical records of newly diagnosed, therapy naïve pediatric patients with CD received with IFX or EEN as induction therapy were retrospectively enrolled. Pediatric Crohn's disease activity index (PCDAI), Crohn's disease endoscopic index of severity (CDEIS), and other clinical data were compared pre- and postinduction therapy in two groups...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36052377/feasibility-and-safety-of-ercp-in-the-treatment-of-biliary-strictures-after-liver-transplantation-with-a-report-of-37-cases
#56
JOURNAL ARTICLE
Fanfan Tang, Jingtao Song, Tanxing Cai, Zhao Lei, Feizhou Huang, Yina Hu, Gang Deng
Background: Liver transplantation (LT) is an effective treatment option for patients with end-stage liver disease; biliary complications are important cause of death in posttransplant patients. Endoscopic retrograde cholangiopancreatography (ERCP) has an irreplaceable role in the diagnosis and treatment of patients with biliary tract disease. Methods: The clinical data of patients with biliary strictures (BS) after LT treated with ERCP admitted to the Third Xiangya Hospital of Central South University from September 2016 to October 2021 were reviewed; the changes in temperature, bilirubin, and albumin before and after treatment and postoperative complications were analyzed...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/36032271/predictors-of-long-time-survivors-in-nonmetastatic-colorectal-signet-ring-cell-carcinoma-a-large-population-based-study
#57
JOURNAL ARTICLE
Wuguang Zhang, Wenqian Gong, Changhai Wu, Mengting Li, Xiaolong Tu
BACKGROUND: Colorectal signet ring cell carcinoma (SRCC) is a rare and distinct subtype of colorectal cancer (CRC), with extremely poor prognosis and aggressive tumor biological behavior. In this study, we aimed to analyze the clinicopathological characteristics and to identify the independent predictors of long-time survivors (LTSs) of nonmetastatic colorectal SRCC. METHODS: Patients diagnosed with nonmetastatic colorectal SRCC were extracted from the Surveillance, Epidemiology, and End Results (SEER) database...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/35991581/performance-of-deep-learning-based-algorithm-for-detection-of-pediatric-intussusception-on-abdominal-ultrasound-images
#58
JOURNAL ARTICLE
Zheming Li, Chunze Song, Jian Huang, Jing Li, Shoujiang Huang, Baoxin Qian, Xing Chen, Shasha Hu, Ting Shu, Gang Yu
Background and Aims: Diagnosing pediatric intussusception from ultrasound images can be a difficult task in many primary care hospitals that lack experienced radiologists. To address this challenge, this study developed an artificial intelligence- (AI-) based system for automatic detection of "concentric circles" signs on ultrasound images, thereby improving the efficiency and accuracy of pediatric intussusception diagnosis. Methods: A total of 440 cases (373 pediatric intussusception and 67 normal cases) were retrospectively collected from Children's Hospital affiliated to Zhejiang University School of Medicine from January 2020 to December 2020...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/35958524/helicobacter-pylori-thioredoxin1-may-play-a-highly-pathogenic-role-via-the-il6-stat3-pathway
#59
JOURNAL ARTICLE
Yanlei Guo, Shigang Ding
Background: Recent studies have shown that CagA is considered highly pathogenic to helicobacter pylori (HP) in Western populations. However, in East Asia, CagA positive HP can be up to 90%, but not all patients will lead to gastric cancer. Our research group has found that HP thioredoxin1 (Trx1) may be a marker of high pathogenicity. Here, we investigate whether HP Trx1 exerts high pathogenicity and its internal molecular mechanism. Materials and Methods: We constructed the coculture system of high-Trx1 HP and low-Trx1 HP strains with gastric epithelial cell lines separately and detected the influence of HP strains...
2022: Gastroenterology Research and Practice
https://read.qxmd.com/read/35935715/efficacy-and-safety-of-exploring-deeper-sections-of-the-infrapapillary-area-of-the-duodenum-by-using-sedative-esophagogastroduodenoscopy
#60
JOURNAL ARTICLE
Ming-Tse Hsu, Chi-Yi Chen, Kai-Sheng Liao, Wei-Sheng Chung
Background: Using conventional esophagogastroduodenoscopy (EGD) to evaluate the infrapapillary area is not feasible. The use of sedative EGD may enable endoscopists to investigate the infrapapillary condition of the duodenum. In this study, we aimed to evaluate lesions in the infrapapillary regions by using sedative EGD. Methods: In this retrospective observational study, we used the data of patients who underwent sedative EGD examinations at a tertiary hospital in southern Taiwan...
2022: Gastroenterology Research and Practice
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