Afrah Alkazemi, Mary Kovacevic, Kevin Dube, Julie C Lauffenburger, Adam Smith, Stephen Malinowski, Gerald L Weinhouse
Introduction: The management of severe hemoptysis mainly consists of invasive interventional procedures, including angiographic bronchial artery embolization, various endobronchial interventions, and sometimes surgery. However, there are limited effective noninvasive medical therapies available. The objective of this analysis was to evaluate the effectiveness and safety of nebulized tranexamic acid (TXA) administration compared with conventional management in patients with hemoptysis. Methods: This Institutional Review Board-approved, single-center, retrospective matched cohort study was performed from January 1, 2018 to March 31, 2021...
December 2023: Journal of Aerosol Medicine and Pulmonary Drug Delivery