journal
Journals Circulation. Arrhythmia and El...

Circulation. Arrhythmia and Electrophysiology

https://read.qxmd.com/read/38497210/comparative-evaluation-of-activity-sensing-rate-responses-of-a-leadless-pacemaker-using-intracardiac-accelerometer-versus-traditional-activity-sensing-pacemaker
#21
LETTER
Jo-Jo Hai, Chu-Pak Lau, Hung-Fat Tse
No abstract text is available yet for this article.
March 18, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38690657/characteristics-of-right-sided-accessory-pathways-associated-with-right-cardiac-veins
#22
JOURNAL ARTICLE
Yiwei Lai, Mingyang Gao, Qifan Li, Mengmeng Li, Jianghua Zhang, Xuexun Li, Qi Guo, Lihong Huang, Chenxi Jiang, Songnan Li, Xueyuan Guo, Song Zuo, Nian Liu, Wei Wang, Xin Zhao, Caihua Sang, Ribo Tang, Deyong Long, Jianzeng Dong, Changsheng Ma
BACKGROUND: The anatomy of myocardial fibers around the right cardiac veins (RCVs) and their roles in accessory pathways (APs) are rarely reported. METHODS: Six RCV-APs were identified from 566 patients with right-sided APs. Mapping of retrograde atrial activation was performed using CARTO 3 system under orthodromic tachycardia or right ventricular pacing. Venography of RCVs was acquired at the earliest retrograde atrial activation. RESULTS: Patients enrolled had a median age of 30 (11-51) years, 5 of them were male...
May 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38426305/genetic-testing-in-brugada-syndrome-a-30-year-experience
#23
JOURNAL ARTICLE
Luigi Pannone, Antonio Bisignani, Randy Osei, Anaïs Gauthey, Antonio Sorgente, Cinzia Monaco, Domenico Giovanni Della Rocca, Alvise Del Monte, Antanas Strazdas, Joerelle Mojica, Maysam Al Housari, Vincenzo Miraglia, Sahar Mouram, Giampaolo Vetta, Gaetano Paparella, Robbert Ramak, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Ströker, Gudrun Pappaert, Juan Sieira, Thomy de Ravel, Mark La Meir, Andrea Sarkozy, Pedro Brugada, Gian Battista Chierchia, Sonia Van Dooren, Carlo de Asmundis
BACKGROUND: A pathogenic/likely pathogenic variant can be found in 20% to 25% of patients with Brugada syndrome (BrS) and a pathogenic/likely pathogenic variant in SCN5A is associated with a worse prognosis. The aim of this study is to define the diagnostic yield of a large gene panel with American College of Medical Genetics and Genomics variant classification and to assess prognosis of SCN5A and non-SCN5A variants. METHODS: All patients with BrS, were prospectively enrolled in the Universitair Ziekenhuis Brussel registry between 1992 and 2022...
April 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38415356/-hras-mutant-cardiomyocyte-model-of-multifocal-atrial-tachycardia
#24
JOURNAL ARTICLE
Nelson A Rodríguez, Nihir Patel, Rafael Dariolli, Simon Ng, Angelika G Aleman, Jingqi Q X Gong, Hung-Mo Lin, Matthew Rodríguez, Rebecca Josowitz, Katia Sol-Church, Karen W Gripp, Xianming Lin, Soomin C Song, Glenn I Fishman, Eric A Sobie, Bruce D Gelb
BACKGROUND: Germline HRAS gain-of-function pathogenic variants cause Costello syndrome (CS). During early childhood, 50% of patients develop multifocal atrial tachycardia, a treatment-resistant tachyarrhythmia of unknown pathogenesis. This study investigated how overactive HRAS activity triggers arrhythmogenesis in atrial-like cardiomyocytes (ACMs) derived from human-induced pluripotent stem cells bearing CS-associated HRAS variants. METHODS: HRAS Gly12 mutations were introduced into a human-induced pluripotent stem cells-ACM reporter line...
April 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38390713/predicting-major-adverse-events-in-patients-undergoing-transcatheter-left-atrial-appendage-occlusion
#25
JOURNAL ARTICLE
Kamil F Faridi, Emily L Ong, Sarah Zimmerman, Paul D Varosy, Daniel J Friedman, Jonathan C Hsu, Fred Kusumoto, Bobak J Mortazavi, Karl E Minges, Lucy Pereira, Dhanunjaya Lakkireddy, Christina Koutras, Beth Denton, Julie Mobayed, Jeptha P Curtis, James V Freeman
BACKGROUND: The National Cardiovascular Data Registry Left Atrial Appendage Occlusion Registry (LAAO) includes the vast majority of transcatheter LAAO procedures performed in the United States. The objective of this study was to develop a model predicting adverse events among patients undergoing LAAO with Watchman FLX. METHODS: Data from 41 001 LAAO procedures with Watchman FLX from July 2020 to September 2021 were used to develop and validate a model predicting in-hospital major adverse events...
April 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38440895/sweetened-beverages-genetic-susceptibility-and-incident-atrial-fibrillation-a-prospective-cohort-study
#26
JOURNAL ARTICLE
Ying Sun, Bowei Yu, Yuefeng Yu, Bin Wang, Xiao Tan, Yingli Lu, Yu Wang, Kun Zhang, Ningjian Wang
BACKGROUND: An association between sweetened beverages and several cardiometabolic diseases has been reported, but their association with atrial fibrillation (AF) is unclear. We aimed to investigate the associations between consumption of sugar-sweetened beverages (SSB), artificially sweetened beverages (ASB), and pure fruit juice (PJ) and risk of consumption with AF risk and further evaluate whether genetic susceptibility modifies these associations. METHODS: A total of 201 856 participants who were free of baseline AF, had genetic data available, and completed a 24-hour diet questionnaire were included...
March 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38440869/artificial-sweeteners-a-new-dietary-environmental-risk-factor-for-atrial-fibrillation
#27
EDITORIAL
Robert A Koeth, Jonathan D Smith, Mina K Chung
No abstract text is available yet for this article.
March 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38426304/is-seeing-believing-adding-another-tool-to-assess-pfa-durability
#28
EDITORIAL
Nishaki Kiran Mehta, David E Haines
No abstract text is available yet for this article.
March 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38318720/cardiac-pulsed-field-ablation-lesion-durability-assessed-by-polarization-sensitive-optical-coherence-reflectometry
#29
JOURNAL ARTICLE
Maria Terricabras, Raphael P Martins, Rafael Peinado, Paweł Derejko, Lluís Mont, Sabine Ernst, David Herranz, Christophe Bailleul, Atul Verma
BACKGROUND: Pulsed field ablation uses electrical fields to cause nonthermal cell death over several hours. Polarization-sensitive optical coherence reflectometry is an optical imaging technique that can detect changes in the tissue ultrastructure in real time, which occurs when muscular tissue is damaged. The objective of this study was to evaluate the ability of a polarization-sensitive optical coherence reflectometry system to predict the development of chronic lesions based on acute changes in tissue birefringence during pulsed field ablation...
March 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38390748/pulsed-field-ablation-index-guided-ablation-for-lesion-formation-impact-of-contact-force-and-number-of-applications-in-the-ventricular-model
#30
JOURNAL ARTICLE
Luigi Di Biase, Jacopo Marazzato, Assaf Govari, Andreas Altman, Christopher Beeckler, Joseph Keyes, Tushar Sharma, Vito Grupposo, Fengwei Zou, Masafumi Sugawara, Atsushi Ikeda, Farshad Raissi, Rahul Bhardwaj, Jonathan C Hsu, Mark Lee, Rajesh Banker, Sanghamitra Mohanty, Andrea Natale, Qi Chen, Paras Parikh, Xiao-Dong Zhang, Hiroshi Nakagawa
BACKGROUND: The effect of contact force (CF) on lesion formation is not clear during pulsed field ablation (PFA). The aim of this study was to evaluate the impact of CF, PFA, and their interplay through the PFA index (PF index) formula on the ventricular lesion size in swine. METHODS: PFA was delivered through the CF-sensing OMNYPULSE catheter. Predefined PFA applications (×3, ×6, ×9, and ×12) were delivered maintaining low (5-25 g), high (26-50 g), and very high (51-80 g) CFs...
February 23, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38390725/differential-pacing-maneuver-from-the-vein-of-marshall
#31
JOURNAL ARTICLE
Naohiko Kawaguchi, Yasuaki Tanaka, Kenji Okubo, Shinichi Tachibana, Emiko Nakashima, Katsumasa Takagi, Hiroyuki Hikita, Tetsuo Sasano, Atsushi Takahashi
BACKGROUND: Bidirectional mitral isthmus (MI) block is conventionally verified by differential pacing from the coronary sinus (CS) and its sequence change. This study aimed to evaluating the ability of differential pacing from the vein of Marshall (VOM) to detect epicardial MI connections. METHODS: Radiofrequency and VOM ethanol MI ablation were performed with a VOM electrode catheter inserted to the septal side of the ablation line. MI block was verified using conventional CS pacing...
February 23, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38390710/development-of-the-nocsae-standard-to-reduce-the-risk-of-commotio-cordis
#32
JOURNAL ARTICLE
Nathan Dau, Cynthia Bir, Elizabeth McCalley, David Halstead, Mark S Link
BACKGROUND: Commotio cordis, sudden cardiac death (SCD) caused by relatively innocent impact to the chest, is one of the leading causes of SCD in sports. Commercial chest protectors have not been demonstrated to mitigate the risk of these SCDs. METHODS: To develop a standard to assess chest protectors, 4 phases occurred. A physiological commotio cordis model was utilized to assess variables that predicted for SCD. Next, a surrogate model was developed based on data from the physiological model, and the attenuation in risk was assessed...
February 23, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38348685/spatially-conserved-spiral-wave-activity-during-human-atrial-fibrillation
#33
JOURNAL ARTICLE
Wouter-Jan Rappel, Tina Baykaner, Junaid Zaman, Prasanth Ganesan, Albert J Rogers, Sanjiv M Narayan
BACKGROUND: Atrial fibrillation is the most common cardiac arrhythmia in the world and increases the risk for stroke and morbidity. During atrial fibrillation, the electric activation fronts are no longer coherently propagating through the tissue and, instead, show rotational activity, consistent with spiral wave activation, focal activity, collision, or partial versions of these spatial patterns. An unexplained phenomenon is that although simulations of cardiac models abundantly demonstrate spiral waves, clinical recordings often show only intermittent spiral wave activity...
February 13, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38344845/utilizing-human-induced-pluripotent-stem-cells-to-study-cardiac-electroporation-pulsed-field-ablation
#34
JOURNAL ARTICLE
Leonid Maizels, Eyal Heller, Michal Landesberg, Shany Glatstein, Irit Huber, Gil Arbel, Amira Gepstein, Doron Aronson, Shirley Sharabi, Roy Beinart, Amit Segev, Elad Maor, Lior Gepstein
BACKGROUND: Electroporation is a promising nonthermal ablation method for cardiac arrhythmia treatment. Although initial clinical studies found electroporation pulsed-field ablation (PFA) both safe and efficacious, there are significant knowledge gaps concerning the mechanistic nature and electrophysiological consequences of cardiomyocyte electroporation, contributed by the paucity of suitable human in vitro models. Here, we aimed to establish and characterize a functional in vitro model based on human-induced pluripotent stem cells (hiPSCs)-derived cardiac tissue, and to study the fundamentals of cardiac PFA...
February 12, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38344811/long-term-outcomes-of-cardiac-resynchronization-therapy-in-patients-with-repaired-tetralogy-of-fallot-a-multicenter-study
#35
JOURNAL ARTICLE
Nawin L Ramdat Misier, Jeremy Moore, Hoang H Nguyen, Michael S Lloyd, Anne M Dubin, Douglas Y Mah, Richard J Czosek, Paul Khairy, Philip M Chang, Jens C Nielsen, Alper Aydin, Thomas A Pilcher, Edward T O'Leary, Kalyanam Shivkumar, Natasja M S de Groot
BACKGROUND: A growing number of patients with tetralogy of Fallot develop left ventricular systolic dysfunction and heart failure, in addition to right ventricular dysfunction. Although cardiac resynchronization therapy (CRT) is an established treatment option, the effect of CRT in this population is still not well defined. This study aimed to investigate the early and late efficacy, survival, and safety of CRT in patients with tetralogy of Fallot. METHODS: Data were analyzed from an observational, retrospective, multicenter cohort, initiated jointly by the Pediatric and Congenital Electrophysiology Society and the International Society of Adult Congenital Heart Disease...
February 12, 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38318697/pulseless-electric-activity-or-electromechanical-dissociation
#36
EDITORIAL
Larisa G Tereshchenko
No abstract text is available yet for this article.
February 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38288627/incidence-and-outcomes-of-new-onset-right-bundle-branch-block-following-transcatheter-aortic-valve-replacement
#37
JOURNAL ARTICLE
Nicholas Y Tan, Demilade Adedinsewo, Abdallah El Sabbagh, Ahmed F Sayed Ahmed, Andrea Carolina Morales-Lara, Mikolaj Wieczorek, Malini Madhavan, Siva K Mulpuru, Abhishek J Deshmukh, Samuel J Asirvatham, Mackram F Eleid, Paul A Friedman, Yong-Mei Cha, Ammar M Killu
BACKGROUND: The incidence and prognosis of right bundle branch block (RBBB) following transcatheter aortic valve replacement (TAVR) are unknown. Hence, we sought to characterize the incidence of post-TAVR RBBB and determine associated risks of permanent pacemaker (PPM) implantation and mortality. METHODS: All patients 18 years and above without preexisting RBBB or PPM who underwent TAVR at US Mayo Clinic sites and Mayo Clinic Health Systems from June 2010 to May 2021 were evaluated...
February 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38284289/artificial-intelligence-model-predicts-sudden-cardiac-arrest-manifesting-with-pulseless-electric-activity-versus-ventricular-fibrillation
#38
JOURNAL ARTICLE
Lauri Holmstrom, Bryan Bednarski, Harpriya Chugh, Habiba Aziz, Hoang Nhat Pham, Arayik Sargsyan, Audrey Uy-Evanado, Damini Dey, Angelo Salvucci, Jonathan Jui, Kyndaron Reinier, Piotr J Slomka, Sumeet S Chugh
BACKGROUND: There is no specific treatment for sudden cardiac arrest (SCA) manifesting as pulseless electric activity (PEA) and survival rates are low; unlike ventricular fibrillation (VF), which is treatable by defibrillation. Development of novel treatments requires fundamental clinical studies, but access to the true initial rhythm has been a limiting factor. METHODS: Using demographics and detailed clinical variables, we trained and tested an AI model (extreme gradient boosting) to differentiate PEA-SCA versus VF-SCA in a novel setting that provided the true initial rhythm...
February 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38284286/long-term-durability-of-high-and-very-high-power-short-duration-pvi-by-invasive-remapping-the-hpsd-remap-study
#39
RANDOMIZED CONTROLLED TRIAL
Nándor Szegedi, Zoltán Salló, Vivien Klaudia Nagy, István Osztheimer, István Hizoh, Bálint Lakatos, Melinda Boussoussou, Gábor Orbán, Márton Boga, Arnold Béla Ferencz, Ferenc Komlósi, Patrik Tóth, Péter Perge, Attila Kovács, Béla Merkely, László Gellér
BACKGROUND: High-power short-duration ablation has shown impressive efficacy and safety for pulmonary vein isolation (PVI); however, initial efficacy results with very high power short-duration ablation were discouraging. This study compared the long-term durability of PVI performed with a 90- versus 50-W power setting. METHODS: Patients were randomized 1:1 to undergo PVI with the QDOT catheter using a power setting of 90 or 50 W. Three months after the index procedure, patients underwent a repeat electrophysiology study to identify pulmonary vein reconnections...
February 2024: Circulation. Arrhythmia and Electrophysiology
https://read.qxmd.com/read/38284238/conduction-system-stimulation-to-avoid-left-ventricle-dysfunction
#40
RANDOMIZED CONTROLLED TRIAL
Carlos E González-Matos, Oriol Rodríguez-Queralto, Fátima Záraket, Jesús Jiménez, Benjamín Casteigt, Ermengol Vallès
BACKGROUND: Right ventricular apical pacing (RVAP) can produce left ventricle dysfunction. Conduction system pacing (CSP) has been used successfully to reverse left ventricle dysfunction in patients with left bundle branch block. To date, data about CSP prevention of left ventricle dysfunction in patients with preserved left ventricular ejection fraction (LVEF) are scarce and limited mostly to nonrandomized studies. Our aim is to demonstrate that CSP can preserve normal ventricular function compared with RVAP in the setting of a high burden of ventricular pacing...
February 2024: Circulation. Arrhythmia and Electrophysiology
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