Ruta Inciuraite, Rolandas Gedgaudas, Rokas Lukosevicius, Deimante Tilinde, Rima Ramonaite, Alexander Link, Neringa Kasetiene, Mindaugas Malakauskas, Gediminas Kiudelis, Laimas Virginijus Jonaitis, Juozas Kupcinskas, Simonas Juzenas, Jurgita Skieceviciene
BACKGROUND: Despite extensive research on microbiome alterations in ulcerative colitis (UC), the role of the constituent stable microbiota remains unclear. RESULTS: This study, employing 16S rRNA-gene sequencing, uncovers a persistent microbial imbalance in both active and quiescent UC patients compared to healthy controls. Using co-occurrence and differential abundance analysis, the study highlights microbial constituents, featuring Phocaeicola, Collinsella, Roseburia, Holdemanella, and Bacteroides, that are not affected during the course of UC...
March 23, 2024: Gut Pathogens