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Clinical and Experimental Otorhinolaryngology

Young-Hoon Joo, Jae-Keun Cho, Bon Seok Koo, Minsu Kwon, Seong Keun Kwon, Soon Young Kwon, Min-Su Kim, Jeong Kyu Kim, Heejin Kim, Innchul Nam, Jong-Lyel Roh, Young Min Park, Il-Seok Park, Jung Je Park, Sung-Chan Shin, Soon-Hyun Ahn, Seongjun Won, Chang Hwan Ryu, Tae Mi Yoon, Giljoon Lee, Doh Young Lee, Myung-Chul Lee, Joon Kyoo Lee, Jin Choon Lee, Jae-Yol Lim, Jae Won Chang, Jeon Yeob Jang, Man Ki Chung, Yuh-Seok Jung, Jae-Gu Cho, Yoon Seok Choi, Jeong-Seok Choi, Guk Haeng Lee, Phil-Sang Chung
Korean Society of Thyroid-Head and Neck Surgery appointed a Task Force to provide guidance on the implementation of a surgical treatment of oral cancer. MEDLINE databases were searched for articles on subjects related to "surgical management of oral cancer" published in English. Results were restricted to systematic reviews, randomized control trials/controlled clinical trials, and observational studies. The quality of evidence was rated with use RoBANS (Risk of Bias Assessment Tool for Nonrandomized Studies) and AMSTAR (A Measurement Tool to Assess the Methodological Quality of Systematic Reviews)...
February 2, 2019: Clinical and Experimental Otorhinolaryngology
Bo Gyung Kim, Hyo Jun Kim, Seung Jae Lee, Eunsang Lee, Se A Lee, Jong Dae Lee
Objectives.: The traditional canal wall down mastoidectomy (CWDM) procedure commonly has potential problems of altering the anatomy and physiology of the middle ear and mastoid. This study evaluated outcomes in patients who underwent modified canal wall down mastoidectomy (mCWDM) and mastoid obliteration using autologous materials. Methods.: Our study included 76 patients with chronic otitis media, cholesteatoma, and adhesive otitis who underwent mCWDM and mastoid obliteration using autologous materials between 2010 and 2015...
February 1, 2019: Clinical and Experimental Otorhinolaryngology
Valentin Favier, Patrice Gallet, Gérard Subsol, Guillaume Captier
No abstract text is available yet for this article.
February 1, 2019: Clinical and Experimental Otorhinolaryngology
Sang-Yeon Lee, Doh Young Lee, Yuju Seo, Young Ho Kim
Although efficacies and proportions of tympanoplasty performed via endoscopic ear surgery (EES) have gradually introduced, it remains unclear whether total EES is a good alternative to microscopic ear surgery (MES). Herein, we aimed to compare therapeutic effects of EES and MES in patients receiving tympanoplasty or myringoplasty. A search of MEDLINE, PubMed, and Embase databases was conducted to compare the efficacies of EES and MES. Two investigators independently reviewed all studies and extracted data with a standardized form...
January 25, 2019: Clinical and Experimental Otorhinolaryngology
Hisami Fujio, Go Inokuchi, Shun Tatehara, Shunsuke Kuroki, Yuriko Fukuda, Hisamoto Kowa, Ken-Ichi Nibu
Objectives: Parkinson disease (PD) is frequently associated with olfactory disorder at early stage, which is caused by deposition of Lewy bodies emerging from the olfactory bulb to higher olfactory centers. Early detection of olfactory disorder in the patients with PD may lead to the early diagnosis and treatment for this refractory disease. Methods: Visual analog scale (VAS), Jet Stream Olfactometry, and Japanese smell identification test, Open Essence (OE), were carried out on 39 patients with PD...
December 27, 2018: Clinical and Experimental Otorhinolaryngology
Hyung-Sik Kim, Junyang Jung, Sung Hwa Dong, Sang Hoon Kim, Su Young Jung, Seung Geun Yeo
Objectives: Factors predictive of the severity of and recovery from Bell's palsy remain unclear. This study evaluated the association between neutrophil to lymphocyte ratio (NLR) and the severity of and recovery from Bell's palsy. Methods: This retrospective study included 51 patients who were hospitalized with Bell's palsy from 2015 to 2017. Degree of paralysis was assessed by House-Brackmann (H-B) grade. Patients with H-B grades 2-4 were classified as having mild to moderate palsy and patients with H-B grade 5 or 6 were classified as having severe palsy...
December 15, 2018: Clinical and Experimental Otorhinolaryngology
Seulki Song, Hyojin Kim, Soon-Hyun Ahn
Objectives: Immunohistochemistry (IHC) has been used for the diagnosis of indeterminate results in fine needle aspiration (FNA) of thyroid nodules. However, the role of IHC in core needle biopsy (CNB) is not clear and the efficacy of testing for molecular markers following CNB has not been evaluated. The aim of this study is to compare the role of IHC staining in CNB with that in FNA when examining thyroid nodules and to compare the sensitivity and usefulness of different molecular markers...
December 11, 2018: Clinical and Experimental Otorhinolaryngology
Eui-Suk Sung, Jin-Choon Lee, Sung-Chan Shin, Hyun-Geun Kwon, Min-Sik Kim, Dong-Jo Kim, Jung-Hoon Ro, Byung-Joo Lee
Objectives: False-negative or false-positive responses in intraoperative neuromonitoring (IONM) using electromyography (EMG) in thyroid surgery pose a challenge. Therefore, we developed a novel IONM system that uses a surface pressure sensor instead of EMG to detect muscle twitching. This study aimed to investigate the feasibility and safety of a new IONM system using a piezo-electric surface pressure sensor in an experimental animal model. Methods: We developed the surface pressure sensor by modifying a commercial piezo-electric sensor...
December 11, 2018: Clinical and Experimental Otorhinolaryngology
Ji Hoon Kim, Sung Su Kim, Young Il Kim, Su Young Jung, Sang Hoon Kim, Seung Geun Yeo
Objectives: Aquaporins (AQPs) are integral membrane proteins engaged in the modulation of water homeostasis, but the roles they play in chronic otitis media (COM) have not been well investigated. Accordingly, we undertook document relations between the mRNA expressions of AQPs and COM, and explored the relation between these expressions and otorrhea, which is one of the most common symptoms of COM. Methods: Levels of the mRNAs of AQP 1, 2, 3, 4, 5, 6, 8, and 10 were assayed by real-time polymerase chain reaction in inflammatory tissue samples from 81 patients with COM with or without otorrhea...
December 7, 2018: Clinical and Experimental Otorhinolaryngology
Chang-Hee Kim, Jung Eun Shin, Myung Hoon Yoo, Hong Ju Park
Objectives: Direction-changing positional nystagmus (PN) was considered to indicate the presence of benign paroxysmal positional vertigo involving lateral semicircular canal in most cases. We investigated the incidence of PN on the supine head-roll test and compared the characteristics of nystagmus in patients with vestibular neuritis (VN) and Meniere disease (MD). Methods: A retrospective review of patients, who were diagnosed with unilateral VN or unilateral definite MD between September 2005 and November 2011, was conducted...
December 5, 2018: Clinical and Experimental Otorhinolaryngology
Jung Joo Lee, Al-Magribi Ahmad Z, Donghyeok Kim, Gwanghui Ryu, Hyo Yeol Kim, Hun-Jong Dhong, Seung-Kyu Chung, Sang Duk Hong
Objectives: Endoscopic prelacrimal medial maxillectomy (EPMM) was previously reported to treat maxillary inverted papilloma. This study aimed to compare prelacrimal recess approach with the conventional Caldwell-Luc approach (CLA) to remove benign maxillary sinus tumors and to evaluate the usefulness of this approach based on our experience. Methods: Ten patients who underwent EPMM at our hospital from January 2013 to December 2017 were reviewed. We also reviewed 30 patients who underwent benign maxillary sinus tumor resection via CLA during the same period...
November 22, 2018: Clinical and Experimental Otorhinolaryngology
Emine Demir, Nazife Nur Afacan, Metin Celiker, Fatma Beyazal Celiker, Mehmet Fatih İnecikli, Suat Terzi, Engin Dursun
Objectives: We explored whether wideband tympanometry (WBT) could be used as a screening test for superior semicircular canal dehiscence (SSCD), and obtained new WBT data (given that the test is not yet in common clinical use) on patients with SSCD. Methods: We compared the WBT data of patients clinically and radiologically diagnosed with SSCD in our hospital between 2013 and 2018 to those of healthy volunteers. We compared the resonance frequency (RF), maximum absorbance frequency (MAF), and maximum absorbance ratio (MAR)...
November 22, 2018: Clinical and Experimental Otorhinolaryngology
Byoung-San Moon, Aswathy Ammothumkandy, Naibo Zhang, Lei Peng, Albina Ibrayeva, Maxwell Bay, Athira Pratap, Hong Ju Park, Michael Anthony Bonaguidi, Wange Lu
OBJECTIVES: Spiral ganglion neurons (SGNs) include potential endogenous progenitor populations for the regeneration of the peripheral auditory system. However, whether these populations are present in adult mice is largely unknown. We examined the presence and characteristics of SGN-neural stem cells (NSCs) in mice as a function of age. METHODS: The expression of Nestin and Ki67 was examined in sequentially dissected cochlear modiolar tissues from mice of different ages (from postnatal day to 24 weeks) and the sphere-forming populations from the SGNs were isolated and differentiated into different cell types...
December 2018: Clinical and Experimental Otorhinolaryngology
Filiz Uzumcugil, Emre Can Celebioglu, Demet Basak Ozkaragoz, Aysun Ankay Yilbas, Basak Akca, Nazgol Lotfinagsh, Bilge Celebioglu
OBJECTIVES: The age-based Cole formula has been employed for the estimation of endotracheal tube (ETT) size due to its ease of use, but may not appropriately consider growth rates among children. Child growth is assessed by calculating the body surface area (BSA). The association between the outer diameter of an appropriate uncuffed-endotrachealtube (ETT-OD) and the BSA values of patients at 24-96 months of age was our primary outcome. METHODS: Cole formula, BSA, age, height, weight and ultrasound measurement of subglottic-transverse-diameter were evaluated for correlations with correct uncuffed ETT-OD...
December 2018: Clinical and Experimental Otorhinolaryngology
Hong Ryul Jin, Dae Woo Kim, Hahn Jin Jung
OBJECTIVES: To investigate the common causes of persistent septal deviation in revision septoplasty and to report the surgical techniques and results to correct them. METHODS: A total of 100 consecutive patients (86 males) who had revision septoplasty due to persistent septal deviation from 2008 and 2014 were included in the study. Their mean age was 35.6 years and the mean follow-up duration was 9.1 months. Presenting symptoms, sites of persistent septal deviation, techniques used to correct the deviation, and surgical results were reviewed...
December 2018: Clinical and Experimental Otorhinolaryngology
Marn Joon Park, Ji Won Kim, Yonghan Kim, Yoon Se Lee, Jong-Lyel Roh, Seung-Ho Choi, Sang Yoon Kim, Soon Yuhl Nam
OBJECTIVES: The current study aims to determine the correlation between nutritional status upon presentation and disease severity, as well as treatment and survival outcomes. METHODS: Patients who were diagnosed with deep neck infection, underwent at least one surgical drainage/debridement, and had more than 1 week of hospitalization at a tertiary medical center from 2007 to 2015 were retrospectively included. Thereafter, initial serum albumin, C-reactive protein (CRP), and body mass index (BMI) were reviewed...
December 2018: Clinical and Experimental Otorhinolaryngology
Nerina Denaro, Marco Carlo Merlano
Prognosis in relapsed metastatic head and neck squamous cell cancer (RM-HNSCC) is dismal. Platinum based chemotherapy in combination with Cetuximab is used in first-line setting, while no further validated options are available at progression. Immunotherapy has produced durable clinical benefit in some patients with RM-HNSCC although the premises are several patients are nonresponders. Studies are ongoing to determine predictive factors and the ideal setting/combination of novel immunotherapies. In this paper, we discuss the past and present of immunotherapy in head and neck cancer and provide an up-to-date information regarding the potential ways to improve immunotherapy outcomes in HNSCC...
December 2018: Clinical and Experimental Otorhinolaryngology
Joo Hyun Park, Jungmin Ahn, Il Joon Moon
OBJECTIVES: As endoscopic instrumentation, techniques and knowledges have significantly improved recently, endoscopic ear surgery has become increasingly popular. Transcanal endoscopic ear surgery (TEES) can provide better visualization of hidden areas in the middle ear cavity during congenital cholesteatoma removal. We aimed to describe outcomes for TEES for congenital cholesteatoma in a pediatric population. METHODS: Twenty-five children (age, 17 months to 9 years) with congenital cholesteatoma confined to the middle ear underwent TEES by an experienced surgeon; 13 children had been classified as Potsic stage I, seven as stage II, and five as stage III...
December 2018: Clinical and Experimental Otorhinolaryngology
Peyman Zamani, Zahra Soleymani, Vahid Rashedi, Farhad Farahani, Gohar Lotf, Mohammad Rezaei
OBJECTIVES: To compare narrative skills between fourth and fifth grades of Persian-speaking students with hearing impairments and typical hearing students of the same grade and also to evaluate the effects of group, sex, hearing age, and educational grade of the students on their spoken/written narrative performance. METHODS: The subjects were 174 students aged 10-13 years, 54 of whom wore cochlear implants, 60 suffered from moderate to severe hearing losses and wore hearing aids, with the remaining 60 students being typical hearing in terms of the sense of hearing...
December 2018: Clinical and Experimental Otorhinolaryngology
Roghayeh Ahmadi, Hamid Jalilvand, Mohammad Ebrahim Mahdavi, Fatemeh Ahmadi, Ali Reza Akbarzade Baghban
OBJECTIVES: Two main digital signal processing technologies inside the modern hearing aid to provide the best conditions for hearing aid users are directionality (DIR) and digital noise reduction (DNR) algorithms. There are various possible settings for these algorithms. The present study evaluates the effects of various DIR and DNR conditions (both separately and in combination) on listening comfort among hearing aid users. METHODS: In 18 participants who received hearing aid fitting services from the Rehabilitation School of Shahid Beheshti University of Medical Sciences regularly, we applied acceptable noise level (ANL) as our subjective measure of listening comfort...
December 2018: Clinical and Experimental Otorhinolaryngology
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