Dental Research Journal

BACKGROUND: This study aimed to assess the effect of local administration of injectable platelet-rich fibrin (i-PRF) on root resorption during orthodontic tooth movement in dogs. MATERIALS AND METHODS: This animal study was conducted on 4 adult male mongrel dogs. The right and left maxillary first premolars of the dogs were extracted, and a Nickel-Titanium closed coil spring was used to connect the canine to the second premolar with 150 g load. Next, 0.5 cc of i-PRF was injected in one quadrant of the maxilla around the second premolar into the periodontal ligament...

BACKGROUND: This study aimed to assess the effect of hydroalcoholic extract of the whole pomegranate fruit on Streptococcus mutans ( S. mutans ) and Lactobacillus acidophilus ( L. acidophilus ) and its clinical effect on dental plaque formation in 8-10-year-old children. MATERIALS AND METHODS: This study was conducted in two phases of in vitro and clinical trial. In the in vitro phase, the antibacterial effect of 50%-50% hydroalcoholic extract of whole pomegranate fruit on S...

BACKGROUND: This study aimed to assess the effect of local injection of injectable platelet-rich fibrin (i-PRF) on bone remodeling during orthodontic tooth movement in dogs. MATERIALS AND METHODS: In this animal study, the maxillary first premolars of four adult male mixed-breed dogs were bilaterally extracted, and a nickel-titanium closed coil spring with 150 g force was placed between the canine and second premolar teeth. One quadrant of the maxilla was randomly selected as the test quadrant, and 0...

BACKGROUND: Dentists begin the diagnosis by identifying and enumerating teeth. Panoramic radiographs are widely used for tooth identification due to their large field of view and low exposure dose. The automatic numbering of teeth in panoramic radiographs can assist clinicians in avoiding errors. Deep learning has emerged as a promising tool for automating tasks. Our goal is to evaluate the accuracy of a two-step deep learning method for tooth identification and enumeration in panoramic radiographs...

BACKGROUND: Few studies assessed the effect of coping material (particularly milled metal copings) on the retentive strength of cements and reported contradictory results. Thus, this study aims to assess the marginal leakage and retentive strength of implant-supported milled zirconia and cobalt-chromium (Co-Cr) copings cemented with different temporary cements. MATERIALS AND METHODS: In this in vitro study, Zirconia and Co-Cr copings were fabricated on 100 straight titanium abutments...

BACKGROUND: A successful endodontic treatment requires a comprehensive knowledge of the root canal morphology. This study compared the diagnostic accuracy of cone-beam computed tomography (CBCT) and the sectioning technique for the assessment of mandibular first molar (MFM) root canal morphology. MATERIALS AND METHODS: In this in vitro , experimental study, 48 eligible MFMs were mounted in 12 blocks (groups of 4) made of acrylic resin and sheep bone powder and underwent CBCT...

BACKGROUND: Charcoal in the composition of some kinds of toothpaste has created concerns regarding abrasiveness and subsequent complications. Considering the popularity of charcoal toothpaste, and the manufacturers' claims that no porosity is caused by activated carbon, this study aimed to compare the effects of two charcoal kinds of toothpaste and three conventional tubes of toothpaste on enamel surface roughness of permanent primary teeth. MATERIALS AND METHODS: This in vitro experimental study evaluated 75 teeth mounted in acrylic resin...

BACKGROUND: The healing process after dental extraction is influenced by various factors, and finding effective strategies for promoting wound healing and reducing postoperative discomfort remains a challenge. This study aimed to evaluate the effectiveness of topical Curcuma longa gel in reducing pain and promoting wound healing after dental extraction, with the secondary objective of assessing the occurrence of dry sockets. The study was a split-mouth randomized controlled trial conducted at the oral and maxillofacial surgery department over 3 months...

BACKGROUND: Horizontal condylar guidance (HCG) is registered by protrusive interocclusal records but in nonarcon articulators, these records can affect the accuracy. The present study aimed to evaluate the effect of a novel rotation coordinating device (RCD) on condylar guidance setting with protrusive interocclusal records. MATERIALS AND METHODS: The study was designed as a comparative in-vitro investigation. Stone maxillary and mandibular casts were mounted on a fully adjustable instrument as the patient...

BACKGROUND: Diode lasers can be used in the treatment of periodontal diseases as they have an anti-bactericidal effect, and regulate oral tissue inflammatory responses. This study aimed to evaluate the adjunctive effects of Diode 940 nm laser on mechanical periodontal debridement. MATERIALS AND METHODS: In this split-mouth single-blind randomized clinical trial, 12 patients were selected. Forty-four oral segments were enrolled in the scaling and root planing (SRP) group and SRP + Laser group with a 1:1 allocation ratio following a simple randomization procedure (coin flip)...

BACKGROUND: The purpose of this study was to conduct a randomized controlled clinical trial to compare and evaluate the effect of provisional restorations fabricated by two techniques, namely, conventional and three-dimensional (3D) printing processes on the peri-implant hard and soft tissues over early nonfunctional loaded implants in the mandibular posterior region. MATERIALS AND METHODS: A randomized controlled clinical trial was conducted across 24 subjects broadly divided into two groups with 12 dental implants each, i...

BACKGROUND: The aim of the present study was to compare dental indexes of pediatric Down syndrome (DS) patients to those who are healthy. MATERIALS AND METHODS: This study was carried out based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement guidelines. The researchers searched title and abstract of major databases, including ProQuest (ProQuest Dissertations and Theses Full Text: Health and Medicine, ProQuest Nursing and Allie Health Source), PubMed, Google Scholar, clinical key, up to date, springer, Cochrane, Scopus, Embase, and Web of Science (ISI), up to September 2020 with restriction to English and Persian language This meta-analysis study had three outcomes: decay/miss/filled index, plaque index, and gingival index...

BACKGROUND: Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer with heterogeneous molecular pathogenesis. Oral lichen planus (OLP) is demonstrated potentially can transfer to OSCC malignant lesions. Unfortunately, there are no definitive prognostic and predictive biomarkers for the clinical management of OSCC patients. The present research is the first study that compared an oral premalignant lesion such as OLP to malignant lesions like OSCC for NOTCH1 expression levels to better understand its oncogenic or tumor suppressive role...

BACKGROUND: Although most of the metabolism of local anesthetics (LAs) takes place in the liver, no study has investigated the effect of these anesthetics on the kidney function of single-kidney humans or animals. The present study was conducted to examine the effect of LAs on renal function in single-kidney rats. MATERIALS AND METHODS: The present experimental animal study with two control groups was done in an animal laboratory. Forty-two rats were randomly assigned to seven groups of six rats, including two control groups and five experimental groups...

BACKGROUND: The retention of cement-retained implant-supported restorations can be affected by surface treatments such as anodizing. This study aimed to assess the effect of the anodization of titanium abutments on their tensile bond strength to implant-supported lithium disilicate (LDS) all-ceramic crowns. MATERIALS AND METHODS: This in vitro , experimental study was conducted on 26 straight abutments in two groups of anodization and control. In the anodization group, seven flat 9 V batteries connected in series were used to generate 64 V energy...

BACKGROUND: This study compared the effect of various grafting materials on the area and volume of minerals attached to dental implants. MATERIALS AND METHODS: In this animal study, 13 dogs were divided into three groups according to the time of sacrificing (2 months, 4 months, or 6 months). The implants were placed in oversized osteotomies, and the residual defects were filled with autograft, bovine bone graft (Cerabone), or a synthetic substitute (Osteon II). At the designated intervals, the dogs were sacrificed and the segmented implants underwent micro-computed tomography analysis...

BACKGROUND: The aim of the present study is to determine the possibility of isolation and characterization of the human periodontal ligament stem cells (hPDLSCs) using limited harvested periodontal ligament (PDL) tissue of only one patient's wisdom teeth (2-4 teeth) under the more compatible terms of use in clinical application without using the fetal bovine serum (FBS). MATERIALS AND METHODS: In this pilot study, hPDLSCs were isolated from the impacted third molar, and tissue was scraped from the roots of the impacted third molar of 10 volunteers to enzymatically digest using collagenase...

BACKGROUND: Previous systematic reviews indicate that there is an increased prevalence of caries in cleft patients in comparison to their healthy control group. To date, the prevalence of caries between unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP) has not been quantitatively evaluated. This review aims to include published studies that examined caries prevalence in patients with UCLP and BCLP to find out whether a quantitative difference exists in caries experience among them...

BACKGROUND: Facial asymmetry is one reason orthodontic patients seek treatment. This study assessed the effect of mandibular asymmetry on facial esthetics and treatment needs perceived by laypersons, orthodontists, and maxillofacial surgeons. MATERIALS AND METHOD: In this descriptive cross-sectional study, the frontal image of a model was captured and symmetrized from the facial midline using Adobe Photoshop software. The mandible was rotated 0°-8° with 1° intervals...

BACKGROUND: Similarity in the appearance of a monolithic restoration with the adjacent teeth is necessary. This study aims to influence the foundation material type and ceramic thickness on the final color of zirconia-reinforced lithium silicate (ZLS) ceramic. MATERIALS AND METHODS: In this experimental study, the A2 translucent blocks of ZLS were sectioned into rectangular specimens with thicknesses 1, 1.5, and 2 mm ( n = 15). Substructure materials include resin composite (B1, D2, A2, A3, and C3), nickel chrome alloy, amalgam, and white and black substrate...