International Journal of Clinical and Experimental Medicine

[This retracts the article on p. 13127 in vol. 8, PMID: 26550235.].

Alzheimer's disease (AD) is a progressive, and often fatal, brain disease that causes neurodegeneration, resulting in memory loss as well as other cognitive and behavioral problems. Here, we propose a novel multimodal method combining independent components from MRI measures and clinical assessments to distinguish Alzheimer's patients or mild cognitive impairment (MCI) subjects from healthy elderly controls. 70 AD subjects (mean age: 77.15 ± 6.2 years), 98 MCI subjects (mean age: 76.91 ± 5.7 years), and 150 HC subjects (mean age: 75...

[This retracts the article on p. 7569 in vol. 8, PMID: 26221301.].

[This retracts the article on p. 4809 in vol. 7, PMID: 25663977.].

[This retracts the article on p. 13235 in vol. 8, PMID: 26550248.].

[This retracts the article on p. 5470 in vol. 8, PMID: 26131125.].

[This retracts the article on p. 17634 in vol. 8, PMID: 26770353.].

The cellular environment of the mammalian heart constantly is challenged with environmental and intrinsic pathological insults, which affect the proper folding of proteins in heart failure. The effects of damaged or misfolded proteins on the cell can be profound and result in a process termed "proteotoxicity". While proteotoxicity is best known for its role in mediating the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, its role in human heart failure also has been recognized. The UPR involves three branches, including PERK, ATF6, and IRE1...

The oncological outcomes of upper tract urothelial carcinoma (UTUC) and bladder cancer (BC) in patients treated with radical surgeries remains controversial. A retrospective analysis of the clinicopathologicla data of 228 consecutive UTUC patients and 174 BC patients treated with radical surgeries from 2000 to 2012 at a high-volume center in China was conducted. Kaplan-Meier method and Cox regression were used to compare overall survival (OS) and cancer-specific survival (CSS) and to find prognostic factors...

[This retracts the article on p. 3338 in vol. 8, PMID: 26064224.].

[This retracts the article on p. 10603 in vol. 8, PMID: 26379850.].

[This retracts the article on p. 12113 in vol. 8, PMID: 26550123.].

[This retracts the article on p. 14944 in vol. 8, PMID: 26628976.].

[This retracts the article on p. 2334 in vol. 8, PMID: 25932170.].

[This retracts the article on p. 16969 in vol. 8, PMID: 26629252.].

[This retracts the article on p. 4131 in vol. 7, PMID: 25550923.].

[This retracts the article on p. 2662 in vol. 8, PMID: 25932216.].

PSMD10, also known as gankyrin, is associated with the proteasome and has been shown to be an oncoprotein in the liver. Here, we report that PSMD10 expression is stimulated by the histone demethylase JMJD2A/KDM4A and its interaction partner, the ETV1 transcription factor, in LNCaP prostate cancer cells. Global analysis of expression patterns revealed that PSMD10 mRNA levels are positively correlated with those of both JMJD2A and ETV1. In human prostate tumors, PSMD10 is highly overexpressed at the protein level and correlates with JMJD2A overexpression; further, PSMD10 expression is enhanced in the prostates of transgenic JMJD2A mice...

[This retracts the article on p. 11428 in vol. 8, PMID: 26379959.].

OBJECTIVE: To explore the feasibility of the Chinese version of Kidney Transplant Questionnaire (KTQ) by evaluating the health-related quality of life (HRQoL) in Chinese recipients of living donor kidney transplantation. METHODS: The English version of KTQ was translated into Chinese and underwent cultural adaptation to obtain the Chinese version of KTQ. HRQoL of 136 Chinese recipients of living donor kidney transplantation that met the inclusion criteria were evaluated to assess the validity and reliability of the questionnaire...