Nanna Julie Olsen, Sofus Christian Larsen, Berit Lilienthal Heitmann
INTRODUCTION: Primary prevention is a public health strategy that hitherto has not been widely applied in obesity prevention research. The objectives were to examine the long-term effects of the Healthy Start primary obesity prevention study, an intervention conducted among healthy weight children susceptible to develop obesity. METHODS: At baseline, children (2-6 years) were randomized allocated to the intervention group (n=271), the control group (n=272), or the shadow control group (n=383)...
June 26, 2024: Obesity Facts
Èlia Navarro-Masip, Nuria Mestres Petit, Blanca Salinas-Roca, Fernando Herrerías, Felip Vilardell, Mari Cruz de la Fuente, Judit Pallares, Maite Santamaría, Marta Zorzano-Martínez, Enric Sánchez, Xavier Matías-Guiu, Carolina López-Cano, Ana Gloria Soler, Josep León-Mengíbar, Marta Bueno, Albert Lecube
INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD), now termed metabolic dysfunction-associated steatotic liver disease (MASLD), is an escalating health concern linked to obesity and type 2 diabetes. Despite liver biopsy being the gold standard, its invasiveness underscores the need for non-invasive diagnostic methods. METHODS: A cross-sectional study was performed to assess MASLD using the non-invasive OWLiver® serum lipidomics test in a cohort of 117 patients with severe obesity undergoing bariatric surgery, comparing outcomes with liver biopsy...
June 26, 2024: Obesity Facts
Jördis Böhme, Claudia Hübner, Thomas Mansfeld, Johannes Sander, Florian Seyfried, Stefan Kaiser, Arne Dietrich, Anja Hilbert
INTRODUCTION: Weight bias internalization (WBI) is associated with reduced psychological well-being in individuals with obesity. The aim of this study was to investigate the application of Cohen's stress buffering model of social support for WBI on well-being in patients presenting for bariatric surgery. METHODS: In N = 804 adult prebariatric patients, WBI, social support, depression severity, health-related quality of life (HRQOL), and self-esteem were assessed by self-report questionnaires...
June 19, 2024: Obesity Facts
(no author information available yet)
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-alcoholic fatty liver disease (NAFLD), is defined as steatotic liver disease (SLD) in the presence of one or more cardiometabolic risk factor(s) and the absence of harmful alcohol intake. The spectrum of MASLD includes steatosis, metabolic dysfunction-associated steatohepatitis (MASH, previously NASH), fibrosis, cirrhosis and MASH-related hepatocellular carcinoma (HCC). This joint EASL-EASD-EASO guideline provides an update on definitions, prevention, screening, diagnosis and treatment for MASLD...
June 7, 2024: Obesity Facts
Ana Marta Pereira, Diogo Moura, Sofia S Pereira, Sara Andrade, Rui Ferreira de Almeida, Mário Nora, Mariana P Monteiro, Marta Guimarães
INTRODUCTION: Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy (SADI-S) is a restrictive/hypoabsorptive procedure recommended for patients with obesity class 3. For safety reasons, SADI-S can be splited into a two-step procedure by performing a sleeve gastrectomy (SG) first. This stepwise approach also provides an unprecedented opportunity to disentangle the weight loss mechanisms triggered by each component. The objective was to compare weight trajectories and postprandial endocrine and metabolic responses of patients with obesity class 3 submitted to SADI-S or sleeve gastrectomy (SG) as the first step of SADI-S...
May 27, 2024: Obesity Facts
Shaopeng Ming, Chunrong Zeng, Haiming Wen, Zhaoyu Li, Ke Qin, Hongtao Liu
Introduction The relationship between BMI and early renal function recovery after kidney transplantation is important due to the rising global obesity rates. Methods A retrospective study on 320 patients who received allograft kidney transplantation at Guangxi Medical University Hospital explored the BMI-kidney function relationship using various statistical methods. Mendelian randomization(MR) was also employed to investigate causality. Results Based on the univariate analysis, multivariate linear regression models, and trend analysis, it was found that there were significant positive correlations between BMI and creatinine, urea, and cystatin C on the 7th day after kidney transplantation (P<0...
May 15, 2024: Obesity Facts
Brendan Jen-Wei Tan, Ling-Ling Chan, Eng-King Tan, Zhi-Dong Zhou
No abstract text is available yet for this article.
May 15, 2024: Obesity Facts
Kelly G H van de Pas, Anita C E Vreugdenhil, Loes Janssen, Wouter K G Leclercq, Meeike Kusters, Malika Chegary, Ines von Rosenstiel, Eric J Hazebroek, Edgar G A H van Mil, Renske Wassenberg, Linda M W Hover, Wim G van Gemert, François M H van Dielen
Introduction In the Netherlands, bariatric surgery in adolescents is currently only allowed in the context of scientific research. Besides this, there was no clinical pathway for bariatric surgery in adolescents. In this paper, the development of a comprehensive clinical pathway for bariatric surgery in adolescents with severe obesity in the is described. Methods The clinical pathway for bariatric surgery in adolescents consists of an eligibility assessment as well as comprehensive peri- and postoperative care...
May 13, 2024: Obesity Facts
Diba Behtaj, Arman Ghorbani, Ghazaleh Eslamian, Nasser Malekpour Alamdari, Maryam Abbasi, Hamid Zand, Azam Shakery, Ghazaleh Shimi, Mohammad Hasan Sohouli, Sepideh Fazeli Taherian
INTRODUCTION: Excessive visceral adiposity is known to drive the onset of metabolic derangements, mostly involving oxidative stress, prolonged inflammation and cellular senescence. N-acetyl cysteine (NAC) is a synthetic form of L-cysteine with potential antioxidant, anti-inflammatory, and anti-senescence properties. This ex-vivo study aimed to determine the effect of NAC on some markers of senescence including β-galactosidase activity and p16, p53, p21, IL-6 and TNF-α gene expressions in visceral adipose tissue in obese adults...
May 8, 2024: Obesity Facts
Manfred J Müller, Anja Bosy-Westphal, Jonathan C K Wells
No abstract text is available yet for this article.
May 3, 2024: Obesity Facts
Jun Lai, Xinqing Li, Zongyan Liu, Yuanyue Liao, Zuomiao Xiao, Yufeng Wei, Yongxiao Cao
INTRODUCTION: Obesity has previously been correlated with an elevated risk of reproductive system diseases in women. The waist-hip ratio (WHR) has been shown to be correlated with visceral fat, making it one of the most commonly used indicators of abdominal obesity. However, little is known about the relationship between WHR and infertility. Therefore, the aim of this study was to evaluate the effect of the WHR on infertility in women of childbearing age. METHODS: The study used cross-sectional data from women aged 20-45 who participated in the National Health and Nutrition Examination Survey (NHANES), which was conducted between 2017 and 2020...
May 2, 2024: Obesity Facts
Seyed Amin Setarehdan, Somayeh Mokhber, Ali Sheidaei, Mohammad Reza Abdolhosseini, Abdolreza Pazouki, Masoud Solaymani-Dodaran
INTRODUCTION: Mortality decrease following bariatric surgery. We explored the extent of the reduction and whether or not it reaches the general population level in a large cohort of patients with obesity. Compare all-cause mortality between patients with obesity who undergo bariatric surgery and those who do not, with the general Iranian population during the same period. METHOD: Data from Iran's National Obesity Surgery Database was used to establish a large cohort of patients registered between 2009 and 2019...
April 24, 2024: Obesity Facts
Guillem Cuatrecasas, Marta Calbo, Olga Rossell, Laia Dachs, Gerardo Aguilar-Soler, Maria-José Coves, Ioana Patrascioiu, Camila Eugenia Benito, Sonia March, Mariona Balfegó, Gabriel Cuatrecasas, Silvana Di Gregorio, Inaki Marina, Pilar Garcia-Lorda, Elena Munoz-Marron, Francisco De Cabo
INTRODUCTION: Ultrasonography in patients with Obesity allows us to measure different layers of abdominal fat (Superficial subcutaneous, Deep subcutaneous, Preperitoneal, Omental and Perirenal), not assessable by DEXA or CT scan. Omental and Perirenal fat depots are considered predictors of metabolic complications. Liraglutide is particularly effective in reducing weight in patients with insulin-resistance, but its direct impact on each abdominal fat layer is unknown. METHODS: We measured, at the L4 level, all 5 abdominal fat depots in 860 patients with obesity (72...
April 20, 2024: Obesity Facts
Adam Abu-Abeid, Anat Bendayan, Jonathan B Yuval, Shai Meron Eldar, Guy Lahat, Yonatan Lessing
BACKGROUND: One anastomosis gastric bypass (OAGB) prevalence is increasing worldwide and shows good mid- to long-term results. Data on long-term outcomes of revisional OAGB (rOAGB) is limited. This study objective is to evaluate the long-term outcomes of patients undergoing primary OAGB (pOAGB) and rOAGB. METHODS: A retrospective analysis of a prospectively maintained patient registry at a single-tertiary center. Patients undergoing OAGB from January 2015 to May 2016 were included and grouped to pOAGB and rOAGB...
April 9, 2024: Obesity Facts
Huanxian Liu, Hongru Zhao, Kaiming Liu, Zhihua Jia, Ming Dong, Yingying Cheng, Yudan Lv, Kang Qu, Wei Gui, Jianjun Chen, Dan Zhang, Zhiliang Fan, Xiaosu Yang, Dongmei Hu, Hongyan Xie, Mingxin Li, Bing Wen, Sufen Chen, Peng Xu, Qingqing Rong, Qiu He, Zhanxiu Ren, Fanhong Yan, Heling Zhao, Min Chen, Tingmin Yu, Hongli Qu, Xingkai An, Huailian Guo, Xinhua Zhang, Xiaoping Pan, Xiaojuan Wang, Shi Qiu, Lvming Zhang, Hongling Zhao, Xin Pan, Qi Wan, Lanyun Yan, Jing Liu, Zhe Yu, Mingjie Zhang, Ye Ran, Xun Han, Zhao Dong, Shengyuan Yu
INTRODUCTION: Medication-overuse headache (MOH) is a secondary chronic headache disorder that occurs in individuals with a pre-existing primary headache disorder, particularly migraine disorder. Obesity is often combined with chronic daily headaches and is considered a risk factor for the transformation of episodic headaches into chronic headaches. However, the association between obesity and MOH among individuals with migraine has rarely been studied. The present study explored the association between body mass index (BMI) and MOH in people living with migraine...
April 3, 2024: Obesity Facts
Renée Stark, Anna Renz, Michael Hanselmann, Christina Haas, Anne Neumann, Oliver Martini, Florian Seyfried, Michael Laxy, Christine Stier, Bettina Zippel-Schultz, Martin Fassnacht, Ann-Cathrin Koschker
INTRODUCTION: Almost 25% of German adults have obesity and numbers are rising, making it an important health issue. Bariatric-metabolic surgery reduces body weight and complications for persons with obesity, but therapeutic success requires long-term post-operative care. Since, no German standards for follow-up by family physicians exist, follow-up is provided by surgical obesity centers, but they are reaching their limits. The ACHT study, funded by the German Innovation Fund, is designed to establish and evaluate the follow-up program, with local physicians following patients supported remotely by obesity centers...
March 27, 2024: Obesity Facts
Nuria Vilarrasa, Javier Salvador, Francisco Poyato, Miguel Ángel Rubio-Herrera
INTRODUCTION: The differences in the prevalence of obesity between the various regions of Spain, partly attributed to socioeconomic differences, may influence the approach to this disease. The aim of this study was to compare differences in attitudes, perception and barriers to the treatment of obesity between people with obesity (PwO) and health care professionals (HCPs), between the different regions of Spain. METHODS: Sub-analysis of the ACTION-IO Spain study, which included 1,500 PwO and 306 HCP belonging to regions with high prevalence of obesity (>16% n=9 regions, HPO group) and low prevalence of obesity (<16% n=8 regions, LPO group) (self-reported data), according to the 2017 National Health Survey of Spain...
March 15, 2024: Obesity Facts
Hazem A Sayed Ahmed, Sohila G Abo El-Ela, Anwar I Joudeh, Sally M Moawd, Samer El Hayek, Jaffer Shah, Nahed A El-Dahshan
INTRODUCTION: Management of obesity is challenging for both patients and healthcare workers. Considering the low success rate of current interventions, this study aimed to explore the prevalence and associated factors of night eating syndrome (NES), insomnia, and psychological distress among individuals with obesity in order to plan comprehensive obesity management interventions. METHODS: A cross-sectional study on a convenient sample from five primary healthcare centers in Port Said, Egypt, was conducted from November 2020 to March 2021...
March 14, 2024: Obesity Facts
Yunhui Wang, Junwu Li, Yulian Zhang, Shiyu Chen, Fang Zheng, Wei Deng
BACKGROUND: The 'obesity paradox' in elderly patients suffering from percutaneous coronary intervention (PCI) remains a source of controversy. The present meta-analysis focused on exploring the real existence of 'obesity paradox' in these patients. METHODS: As of November 2022, PubMed, Cochrane and Embase databases were comprehensively searched to identify articles reporting all-cause mortality according to diverse body mass index (BMI) categories after PCI among the old cases developing coronary artery disease (CAD)...
February 14, 2024: Obesity Facts
Simon Schraven, Claudia Hübner, Janina Eichler, Thomas Mansfeld, Johannes Sander, Florian Seyfried, Stefan Kaiser, Arne Dietrich, Ricarda Schmidt, Anja Hilbert
Introduction The Weight Bias Internalization Scale and the Modified Weight Bias Internalization Scale are well-established self-report questionnaires for assessing weight bias internalization, which is widespread among bariatric patients. However, among this group, psychometric properties of the Weight Bias Internalization Scale have only been examined in small samples showing unsatisfactory model fit and have not been explored for the modified questionnaire. Methods This study psychometrically evaluated and compared the Weight Bias Internalization Scale and Modified Weight Bias Internalization Scale in a large sample of prebariatric patients (N=825, mean age=46...
February 13, 2024: Obesity Facts
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